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35 Companies |
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34 Products |
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34 Products |
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43 Mechanisms of Action |
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0 Trials |
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224 News |
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- | Trial completion date: Efficacy of MUCIPLIQ on the Incidence of Radio-chemotherapy-induced Mucositis in Patients Suffering From Oral Cancer (clinicaltrials.gov) - May 14, 2014
P=N/A, N=105, Recruiting, Sponsor: Organ, Tissue, Regeneration, Repair and Replacement
Trial completion date: Jun 2014 --> Jun 2015
- | doxepin / Generic mfg.
Enrollment closed: Doxepin Hydrochloride in Treating Oral Mucositis Pain in Patients With Head and Neck Cancer Undergoing Radiation Therapy With or Without Chemotherapy (clinicaltrials.gov) - May 13, 2014
P3, N=162, Active, not recruiting, Sponsor: Alliance for Clinical Trials in Oncology
Trial completion date: Jun 2014 --> Jun 2015 Recruiting --> Active, not recruiting
- melphalan / Generic mfg.
Enrollment closed: Randomized Trial of Cryotherapy Duration Prior to High Dose Melphalan in Myeloma Patients (clinicaltrials.gov) - May 11, 2014
P2, N=140, Active, not recruiting, Sponsor: Ohio State University Comprehensive Cancer Center
Recruiting --> Active, not recruiting Recruiting --> Active, not recruiting
- | celecoxib oral / Generic mfg.
Trial completion: Cox-2 Inhibition in Radiation-induced Oral Mucositis (clinicaltrials.gov) - May 6, 2014
P2, N=43, Completed, Sponsor: University of Connecticut Health Center
Recruiting --> Active, not recruiting Active, not recruiting --> Completed
- acetylcysteine solution / Generic mfg.
Enrollment open: Acetylcysteine Rinse in Reducing Saliva Thickness and Mucositis in Patients With Head and Neck Cancer Undergoing Radiation Therapy (clinicaltrials.gov) - Apr 30, 2014
P=N/A, N=36, Recruiting, Sponsor: Mayo Clinic
Active, not recruiting --> Completed Not yet recruiting --> Recruiting
- |||| Trial completion, HEOR, Cost effectiveness: Pharmaco-economic Study of a New Medical Device Performed From the Perspective of the Hospital (clinicaltrials.gov) - Apr 28, 2014
P2, N=92, Completed, Sponsor: Nantes University Hospital
Not yet recruiting --> Recruiting Recruiting --> Completed
- Trial initiation date: Feasibility Study of Low Level Light Therapy for Prevention of Oropharyngeal Mucositis in Pediatric Transplants Patients (clinicaltrials.gov) - Apr 27, 2014
P=N/A, N=12, Recruiting, Sponsor: Dana-Farber Cancer Institute
Recruiting --> Completed Initiation date: May 2014 --> Apr 2014
- Enrollment open: Feasibility Study of Low Level Light Therapy for Prevention of Oropharyngeal Mucositis in Pediatric Transplants Patients (clinicaltrials.gov) - Apr 27, 2014
P=N/A, N=12, Recruiting, Sponsor: Dana-Farber Cancer Institute
Initiation date: May 2014 --> Apr 2014 Not yet recruiting --> Recruiting
- Clinical: Acetylcysteine Rinse in Reducing Saliva Thickness and Mucositis in Patients With Head and Neck Cancer Undergoing Radiation Therapy (clinicaltrials.gov) - Apr 23, 2014
P=N/A, N=36, Recruiting, Sponsor: Mayo Clinic
- Enrollment open: The FOCCUS Study: "Focusing on Cancers Chemotherapys' Untreated Symptoms" (clinicaltrials.gov) - Apr 21, 2014
P=N/A, N=500, Recruiting, Sponsor: Royal Marsden NHS Foundation Trust
Not yet recruiting --> Recruiting Not yet recruiting --> Recruiting
- Clinical: Feasibility Study of Low Level Light Therapy for Prevention of Oropharyngeal Mucositis in Pediatric Transplants Patients (clinicaltrials.gov) - Apr 20, 2014
P=N/A, N=12, Recruiting, Sponsor: Dana-Farber Cancer Institute
- Kepivance (palifermin) / SOBI, Amgen
Trial termination, Surgery, Metastases: Palifermin in Lessening Oral Mucositis in Patients Undergoing Radiation Therapy and Chemotherapy for Locally Advanced Head and Neck Cancer (clinicaltrials.gov) - Apr 15, 2014
P3, N=21, Terminated, Sponsor: Radiation Therapy Oncology Group
Not yet recruiting --> Recruiting Completed --> Terminated; Due to positive preliminary results from other palifermin studies.
- Kepivance (palifermin) / SOBI, Amgen, peripheral blood stem cell transplantation / National Cancer Institute
Trial completion: Melphalan and Palifermin in Treating Patients Undergoing An Autologous Peripheral Stem Cell Transplant for Stage II or III Multiple Myeloma (clinicaltrials.gov) - Apr 13, 2014
P1, N=38, Completed, Sponsor: Barbara Ann Karmanos Cancer Institute
Completed --> Terminated; Due to positive preliminary results from other palifermin studies. Active, not recruiting --> Completed
- | triamcinolone acetonide / Generic mfg.
New P1/2 trial: Comparing Triamcinolone Acetonide Mucoadhesive Films With Licorice Mucoadhesive Films (clinicaltrials.gov) - Feb 27, 2014
P1/2, N=60, Completed, Sponsor: Isfahan University of Medical Sciences
- | melphalan / Generic mfg.
Trial completion: Ice Chips or Saline Mouth Rinse in Reducing or Preventing Mucositis in Patients Receiving Melphalan and Autologous Stem Cell Transplant for Multiple Myeloma (clinicaltrials.gov) - Feb 22, 2014
P=N/A, N=41, Completed, Sponsor: Fred Hutchinson Cancer Research Center
Active, not recruiting --> Completed No longer recruiting --> Completed
- | NN1213 / Novo Nordisk
Trial completion: Effect of an Anti-Inflammatory Drug on Gut Mucosa in HIV Infected Patients (clinicaltrials.gov) - Feb 22, 2014
P1, N=14, Completed, Sponsor: National Institute of Allergy and Infectious Diseases (NIAID)
No longer recruiting --> Completed No longer recruiting --> Completed
- | NN1213 / Novo Nordisk
Trial completion: Laser Therapy in Preventing Oral Mucositis in Patients Undergoing Bone Marrow Transplantation (clinicaltrials.gov) - Feb 22, 2014
P2/3, N=0, Completed, Sponsor: Fred Hutchinson Cancer Research Center
No longer recruiting --> Completed Active, not recruiting --> Completed
- | Leukine (sargramostim) / Partner Therap
Trial completion: Sargramostim in Decreasing Mucositis in Patients Receiving Radiation Therapy for Head and Neck Cancer (clinicaltrials.gov) - Feb 19, 2014
P3, N=0, Completed, Sponsor: Radiation Therapy Oncology Group
Active, not recruiting --> Completed No longer recruiting --> Completed
- morphine sulphate / Generic mfg.
Trial completion: Topical Morphine for Stomatitis-related Pain Induced by Chemotherapy (clinicaltrials.gov) - Feb 19, 2014
P4, N=72, Completed, Sponsor: Danish University of Pharmaceutical Sciences
No longer recruiting --> Completed Recruiting --> Completed
- Trial completion: Evaluation of the Role of Prostaglandins in Radiation-induced Mucositis (clinicaltrials.gov) - Feb 2, 2014
P=N/A, N=9, Completed, Sponsor: University of Vermont
Recruiting --> Completed Recruiting --> Completed
- Enrollment open: CP073: Intranasal Transmucosal Fentanyl Pectin for Breakthrough Cancer Pain in Radiation-induced Oropharyngeal Mucositis (clinicaltrials.gov) - Jan 28, 2014
P=N/A, N=31, Recruiting, Sponsor: Grupo de Investigaci
Recruiting --> Completed Not yet recruiting --> Recruiting
- Sativex (nabiximols) / Jazz
Enrollment open: A Pharmacokinetic Study of Single Doses of Sativex in Treatment-induced Mucositis (clinicaltrials.gov) - Jan 26, 2014
P1, N=24, Recruiting, Sponsor: GW Pharmaceuticals Ltd.
Not yet recruiting --> Recruiting Not yet recruiting --> Recruiting
- methotrexate IV / Generic mfg., leucovorin calcium / Generic mfg.
Enrollment change: CRUK-BRD/07/004: Methotrexate, Glucarpidase, and Leucovorin in Treating Patients With Newly Diagnosed Primary Central Nervous System Lymphoma (clinicaltrials.gov) - Jan 23, 2014
P1/2, N=4, Completed, Sponsor: University College, London
Not yet recruiting --> Recruiting N=20 --> 4
- methotrexate IV / Generic mfg., leucovorin calcium / Generic mfg.
Trial completion: CRUK-BRD/07/004: Methotrexate, Glucarpidase, and Leucovorin in Treating Patients With Newly Diagnosed Primary Central Nervous System Lymphoma (clinicaltrials.gov) - Jan 23, 2014
P1/2, N=4, Completed, Sponsor: University College, London
N=20 --> 4 Recruiting --> Completed
- |||| dusquetide (SGX942) / Soligenix
Enrollment open: A Dose Escalating Study of SGX942 for Oral Mucositis in Patients With Head and Neck Cancer (clinicaltrials.gov) - Jan 6, 2014
P2, N=78, Recruiting, Sponsor: Soligenix
Recruiting --> Completed Active, not recruiting --> Recruiting
- New P4 trial: Non Surgical Treatment of Periimplantitis (clinicaltrials.gov) - Dec 26, 2013
P4, N=20, Recruiting, Sponsor: Proed
- methotrexate IV / Generic mfg.
New P2 trial, Adverse events: Will Glucarpidase After Methotrexate Treatment for Bone Sarcoma Lead to Fewer Side Effects and Reduce Chemotherapy Delays? (clinicaltrials.gov) - Dec 25, 2013
P2, N=38, Recruiting, Sponsor: University College, London
- TXA-127 / Constant Therap
Trial withdrawal: Efficacy Study of a TXA127 to Reduce Graft-vs-Host Disease in Subjects Undergoing Allogeneic Peripheral Blood Stem Cell Transplantation (clinicaltrials.gov) - Dec 17, 2013
P2, N=0, Withdrawn, Sponsor: US Biotest, Inc.
Active, not recruiting --> Recruiting Not yet recruiting --> Withdrawn
- TXA-127 / Constant Therap
Trial withdrawal: Efficacy Study of a TXA127 to Reduce Acute Graft-vs-Host Disease in Subjects Undergoing Double Umbilical Cord Blood Transplantation (clinicaltrials.gov) - Dec 17, 2013
P2, N=0, Withdrawn, Sponsor: US Biotest, Inc.
Not yet recruiting --> Withdrawn Not yet recruiting --> Withdrawn
- TXA-127 / Constant Therap
Trial withdrawal: Evaluation of the Safety and Efficacy of TXA127 (Angiotensin 1-7) to Enhance Engraftment in Pediatric Patients Undergoing Single or Double Umbilical Cord Blood Transplantation (clinicaltrials.gov) - Dec 17, 2013
P2, N=0, Withdrawn, Sponsor: US Biotest, Inc.
Not yet recruiting --> Withdrawn Recruiting --> Withdrawn
- TXA-127 / Constant Therap
Enrollment change: Efficacy Study of a TXA127 to Reduce Graft-vs-Host Disease in Subjects Undergoing Allogeneic Peripheral Blood Stem Cell Transplantation (clinicaltrials.gov) - Dec 17, 2013
P2, N=0, Withdrawn, Sponsor: US Biotest, Inc.
Recruiting --> Withdrawn N=40 --> 0
- TXA-127 / Constant Therap
Enrollment change: Efficacy Study of a TXA127 to Reduce Acute Graft-vs-Host Disease in Subjects Undergoing Double Umbilical Cord Blood Transplantation (clinicaltrials.gov) - Dec 17, 2013
P2, N=0, Withdrawn, Sponsor: US Biotest, Inc.
N=40 --> 0 N=20 --> 0
- TXA-127 / Constant Therap
Enrollment change: Evaluation of the Safety and Efficacy of TXA127 (Angiotensin 1-7) to Enhance Engraftment in Pediatric Patients Undergoing Single or Double Umbilical Cord Blood Transplantation (clinicaltrials.gov) - Dec 17, 2013
P2, N=0, Withdrawn, Sponsor: US Biotest, Inc.
N=20 --> 0 N=15 --> 0
- ||||| dusquetide (SGX942) / Soligenix
New P2 trial: A Dose Escalating Study of SGX942 for Oral Mucositis in Patients With Head and Neck Cancer (clinicaltrials.gov) - Dec 15, 2013
P2, N=78, Recruiting, Sponsor: Soligenix
- Zyclara (imiquimod) / Mochida, Viatris, Bausch Health
Biomarker, Enrollment change: Identification of Novel Biomarkers of Cervicovaginal Mucosal Inflammation (clinicaltrials.gov) - Dec 10, 2013
P2, N=39, Completed, Sponsor: CONRAD
N=15 --> 0 N=30 --> 39
- Zyclara (imiquimod) / Mochida, Viatris, Bausch Health
Biomarker, Trial completion: Identification of Novel Biomarkers of Cervicovaginal Mucosal Inflammation (clinicaltrials.gov) - Dec 10, 2013
P2, N=39, Completed, Sponsor: CONRAD
N=30 --> 39 Active, not recruiting --> Completed
- | pilocarpine / Generic mfg.
Trial completion: Pilocarpine in Preventing Mucositis and Dry Mouth in Patients Receiving Radiation Therapy for Head and Neck Cancer (clinicaltrials.gov) - Dec 10, 2013
P3, N=249, Completed, Sponsor: Radiation Therapy Oncology Group
Active, not recruiting --> Completed Active, not recruiting --> Completed
- entolimod (STAT-600) / Coeptis
Trial withdrawal, Metastases: Entolimod in Treating Patients With Stage III-IV Squamous Cell Head and Neck Cancer Receiving Cisplatin and Radiation Therapy (clinicaltrials.gov) - Dec 9, 2013
P1, N=0, Withdrawn, Sponsor: Roswell Park Cancer Institute
Active, not recruiting --> Completed Not yet recruiting --> Withdrawn
- entolimod (STAT-600) / Coeptis
Enrollment change, Metastases: Entolimod in Treating Patients With Stage III-IV Squamous Cell Head and Neck Cancer Receiving Cisplatin and Radiation Therapy (clinicaltrials.gov) - Dec 9, 2013
P1, N=0, Withdrawn, Sponsor: Roswell Park Cancer Institute
Not yet recruiting --> Withdrawn N=36 --> 0
- | Humira (adalimumab) / AbbVie
Trial initiation date: ADACAL: Assessment of Mucosal Activity to Improve the Prognosis of Patients With Crohn's Disease Treated With Immunosuppressants (clinicaltrials.gov) - Nov 14, 2013
P3, N=160, Recruiting, Sponsor: Grupo Espanol de Trabajo en Enfermedad de Crohn y Colitis Ulcerosa
N=36 --> 0 Initiation date: Mar 2012 --> Oct 2012
- | Humira (adalimumab) / AbbVie
Enrollment open: ADACAL: Assessment of Mucosal Activity to Improve the Prognosis of Patients With Crohn's Disease Treated With Immunosuppressants (clinicaltrials.gov) - Nov 14, 2013
P3, N=160, Recruiting, Sponsor: Grupo Espanol de Trabajo en Enfermedad de Crohn y Colitis Ulcerosa
Initiation date: Mar 2012 --> Oct 2012 Not yet recruiting --> Recruiting
- ||| Trial completion: A Comparative Investigation of Standard Of Care (SOC) and Episil (clinicaltrials.gov) - Nov 5, 2013
P=N/A, N=116, Completed, Sponsor: Camurus AB
Not yet recruiting --> Recruiting Recruiting --> Completed
- | Sativex (nabiximols) / Jazz
New P1 trial: A Pharmacokinetic Study of Single Doses of Sativex in Treatment-induced Mucositis (clinicaltrials.gov) - Nov 3, 2013
P1, N=24, Recruiting, Sponsor: GW Pharmaceuticals Ltd.
- Leukine (sargramostim) / Partner Therap
Trial completion: Sargramostim to Prevent Mucositis in Patients Receiving Radiation Therapy for Laryngeal Cancer (clinicaltrials.gov) - Oct 31, 2013
P2, N=0, Completed, Sponsor: Royal Marsden NHS Foundation Trust
Recruiting --> Completed Active, not recruiting --> Completed
- New P2 trial: Use of Probiotics in Oral Health of Patients With Dental Implants (clinicaltrials.gov) - Oct 30, 2013
P2, N=34, Completed, Sponsor: University of Valencia
- Trial completion: Use of Probiotics in Oral Health of Patients With Dental Implants (clinicaltrials.gov) - Oct 26, 2013
P2, N=34, Completed, Sponsor: University of Valencia
Active, not recruiting --> Completed Not yet recruiting --> Completed
- Enrollment open: Experimental Peri-implant Mucositis in Humans (clinicaltrials.gov) - Sep 11, 2013
P=N/A, N=15, Recruiting, Sponsor: University of Connecticut Health Center
Not yet recruiting --> Completed Not yet recruiting --> Recruiting
- Enrollment open: ROSAM: Role of SAMITAL (clinicaltrials.gov) - Sep 9, 2013
P2, N=120, Recruiting, Sponsor: Istituto Oncologico Veneto IRCCS
Not yet recruiting --> Recruiting Not yet recruiting --> Recruiting
- |||| Trial completion: A Study to Evaluate the Efficacy of MuGard for the Amelioration of Oral Mucositis in Head and Neck Cancer Patients (clinicaltrials.gov) - Sep 9, 2013
P4, N=120, Completed, Sponsor: Access Pharmaceuticals, Inc.
Not yet recruiting --> Recruiting Recruiting --> Completed
- Biomarker, New P2 trial, HEOR: Study of Personalized Sterile Humidification Device for Mucositis in Head and Neck Cancer Patients (clinicaltrials.gov) - Aug 27, 2013
P2, N=20, Recruiting, Sponsor: University of California, San Francisco