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35 Companies |
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34 Products |
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34 Products |
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43 Mechanisms of Action |
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0 Trials |
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224 News |
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- | Phase classification: Use of Chamomilla Recutita in Mucositis (clinicaltrials.gov) - May 15, 2023
P=N/A, N=40, Completed, Sponsor: University of Sao Paulo
Phase classification: P2 --> P=N/A
- | acetylcysteine solution / Generic mfg.
Trial completion, Trial completion date: Acetylcysteine Rinse in Reducing Saliva Thickness and Mucositis in Patients With Head and Neck Cancer Undergoing Radiation Therapy (clinicaltrials.gov) - Apr 30, 2019
P2, N=34, Completed, Sponsor: Mayo Clinic
Phase classification: P2 --> P=N/A Active, not recruiting --> Completed | Trial completion date: May 2019 --> Jul 2018
- | acetylcysteine solution / Generic mfg.
Enrollment change, Trial completion date: Acetylcysteine Rinse in Reducing Saliva Thickness and Mucositis in Patients With Head and Neck Cancer Undergoing Radiation Therapy (clinicaltrials.gov) - Apr 19, 2019
P2, N=34, Active, not recruiting, Sponsor: Mayo Clinic
Active, not recruiting --> Completed | Trial completion date: May 2019 --> Jul 2018 N=18 --> 34 | Trial completion date: Dec 2018 --> May 2019
- | acetylcysteine solution / Generic mfg.
Phase classification: Acetylcysteine Rinse in Reducing Saliva Thickness and Mucositis in Patients With Head and Neck Cancer Undergoing Radiation Therapy (clinicaltrials.gov) - Oct 31, 2018
P2, N=18, Active, not recruiting, Sponsor: Mayo Clinic
N=18 --> 34 | Trial completion date: Dec 2018 --> May 2019 Phase classification: P=N/A --> P2
- | Trial completion, Trial completion date, Trial primary completion date: Analgesic Effects of Topical Ketamine Mouthwash in Patients Receiving Chemoradiation or Radiotherapy for Head & Neck Cancer (clinicaltrials.gov) - Sep 28, 2018
P2, N=11, Completed, Sponsor: Dartmouth-Hitchcock Medical Center
Phase classification: P=N/A --> P2 Recruiting --> Completed | Trial completion date: Jan 2017 --> Aug 2016 | Trial primary completion date: Jan 2017 --> Aug 2016
- | NN1213 / Novo Nordisk
Trial completion, Trial completion date: ROSAM: Role of SAMITAL (clinicaltrials.gov) - Jul 20, 2018
P2, N=120, Completed, Sponsor: Istituto Oncologico Veneto IRCCS
Recruiting --> Completed | Trial completion date: Jan 2017 --> Aug 2016 | Trial primary completion date: Jan 2017 --> Aug 2016 Active, not recruiting --> Completed | Trial completion date: Dec 2016 --> Jan 2018
- | NN1213 / Novo Nordisk
Trial completion, Phase classification: Early Use of Opioid in Radiation Mucositis (clinicaltrials.gov) - Jul 17, 2018
P2, N=200, Completed, Sponsor: Affiliated Cancer Hospital & Institute of Guangzhou Medical University
Active, not recruiting --> Completed | Trial completion date: Dec 2016 --> Jan 2018 Not yet recruiting --> Completed | Phase classification: PN/A --> P2
- | melphalan / Generic mfg.
Enrollment change, Trial completion date, Trial termination, Trial primary completion date: Cryotherapy in the Prevention of Chemotherapy-Induced Mucositis in Stem Cell Transplant (clinicaltrials.gov) - Apr 23, 2018
P=N/A, N=29, Terminated, Sponsor: University of Florida
Not yet recruiting --> Completed | Phase classification: PN/A --> P2 N=60 --> 29 | Trial completion date: Mar 2019 --> Dec 2017 | Recruiting --> Terminated | Trial primary completion date: Mar 2018 --> Dec 2017; Interim analysis: results of the analysis showed no significant difference between the two study groups
- | acetylcysteine solution / Generic mfg.
Trial completion date: Acetylcysteine Rinse in Reducing Saliva Thickness and Mucositis in Patients With Head and Neck Cancer Undergoing Radiation Therapy (clinicaltrials.gov) - Apr 18, 2018
P=N/A, N=18, Active, not recruiting, Sponsor: Mayo Clinic
N=60 --> 29 | Trial completion date: Mar 2019 --> Dec 2017 | Recruiting --> Terminated | Trial primary completion date: Mar 2018 --> Dec 2017; Interim analysis: results of the analysis showed no significant difference between the two study groups Trial completion date: Apr 2018 --> Dec 2018
- |||| Trial completion: Safety and Efficacy of IZN-6N4 Oral Rinse for the Prevention of Oral Mucositis in Patients With Head and Neck Cancer (clinicaltrials.gov) - Mar 13, 2018
P2, N=110, Completed, Sponsor: Izun Pharma Ltd
Trial completion date: Apr 2018 --> Dec 2018 Active, not recruiting --> Completed
- | Phase classification, Trial termination, Trial primary completion date: Honey in Chronic Immune Thrombocytopenia (clinicaltrials.gov) - Jan 9, 2018
P=N/A, N=30, Terminated, Sponsor: mamdouh abdulmaksoud abdulrhman
Active, not recruiting --> Completed Phase classification: P2 --> P=N/A | Suspended --> Terminated | Trial primary completion date: Jan 2017 --> Dec 2017; problem with the candidate (investigator)
- | melphalan / Generic mfg.
Enrollment change: Cryotherapy in the Prevention of Chemotherapy-Induced Mucositis in Stem Cell Transplant (clinicaltrials.gov) - Dec 13, 2017
P=N/A, N=60, Recruiting, Sponsor: University of Florida
Phase classification: P2 --> P=N/A | Suspended --> Terminated | Trial primary completion date: Jan 2017 --> Dec 2017; problem with the candidate (investigator) N=48 --> 60
- |||| brilacidin (PMX-30063) / Innovation Pharma
Trial completion, Trial initiation date: Study of the Effects of Brilacidin Oral Rinse on Radiation-induced Oral Mucositis in Patients With Head and Neck Cancer (clinicaltrials.gov) - Nov 28, 2017
P2, N=61, Completed, Sponsor: Cellceutix Corporation
N=48 --> 60 Active, not recruiting --> Completed | Initiation date: May 2015 --> Aug 2014
- | Trial completion: The FOCCUS Study: "Focusing on Cancers Chemotherapys' Untreated Symptoms" (clinicaltrials.gov) - Nov 22, 2017
P=N/A, N=248, Completed, Sponsor: Royal Marsden NHS Foundation Trust
Active, not recruiting --> Completed | Initiation date: May 2015 --> Aug 2014 Active, not recruiting --> Completed
- ||| brilacidin (PMX-30063) / Innovation Pharma
Enrollment closed: Study of the Effects of Brilacidin Oral Rinse on Radiation-induced Oral Mucositis in Patients With Head and Neck Cancer (clinicaltrials.gov) - Aug 29, 2017
P2, N=61, Active, not recruiting, Sponsor: Cellceutix Corporation
Active, not recruiting --> Completed Recruiting --> Active, not recruiting
- | doxepin / Generic mfg.
Trial completion: Doxepin Hydrochloride in Treating Oral Mucositis Pain in Patients With Head and Neck Cancer Undergoing Radiation Therapy With or Without Chemotherapy (clinicaltrials.gov) - Aug 9, 2017
P3, N=155, Completed, Sponsor: Alliance for Clinical Trials in Oncology
Recruiting --> Active, not recruiting Active, not recruiting --> Completed
- | Enrollment change, Trial withdrawal: CD2 Lozenges in Preventing Acute Oral Mucositis in Patients With Head and Neck Cancer Receiving Radiotherapy and Chemotherapy (clinicaltrials.gov) - Aug 8, 2017
P3, N=0, Withdrawn, Sponsor: Alliance for Clinical Trials in Oncology
Active, not recruiting --> Completed N=148 --> 0 | Active, not recruiting --> Withdrawn
- |||| dusquetide (SGX942) / Soligenix
Trial completion, Enrollment change: A Dose Escalating Study of SGX942 for Oral Mucositis in Patients With Head and Neck Cancer (clinicaltrials.gov) - Jul 31, 2017
P2, N=111, Completed, Sponsor: Soligenix
N=148 --> 0 | Active, not recruiting --> Withdrawn Active, not recruiting --> Completed | N=78 --> 111
- | melphalan / Generic mfg.
Phase classification: Cryotherapy in the Prevention of Chemotherapy-Induced Mucositis in Stem Cell Transplant (clinicaltrials.gov) - Jul 6, 2017
P=N/A, N=48, Recruiting, Sponsor: University of Florida
Active, not recruiting --> Completed | N=78 --> 111 Phase classification: P1/2 --> P=N/A
- | melphalan / Generic mfg.
Phase classification: Randomized Trial of Cryotherapy Duration Prior to High Dose Melphalan in Myeloma Patients (clinicaltrials.gov) - Jun 27, 2017
P=N/A, N=148, Completed, Sponsor: Ohio State University Comprehensive Cancer Center
Phase classification: P1/2 --> P=N/A Phase classification: P2 --> P=N/A
- | Trial completion, Enrollment change: Experimental Peri-implant Mucositis in Humans (clinicaltrials.gov) - Apr 26, 2017
P=N/A, N=18, Completed, Sponsor: UConn Health
Phase classification: P2 --> P=N/A Active, not recruiting --> Completed | N=15 --> 18
- ||||||| Torisel (temsirolimus) / Pfizer
Trial completion, Trial primary completion date, Stroma: COMTT: Caphosol in Oral Mucositis Due to Targeted Therapy (clinicaltrials.gov) - Feb 11, 2017
P3, N=64, Completed, Sponsor: Christine B Boers-Doets
Active, not recruiting --> Completed | N=15 --> 18 Recruiting --> Completed | Trial primary completion date: Feb 2014 --> Aug 2015
- |||| carboplatin / Generic mfg., amifostine / Generic mfg., paclitaxel / Generic mfg.
Trial completion, Enrollment change, Trial primary completion date, Metastases: Randomized Amifostine For SCCHN (clinicaltrials.gov) - Jan 4, 2017
P2, N=58, Completed, Sponsor: Dana-Farber Cancer Institute
Recruiting --> Completed | Trial primary completion date: Feb 2014 --> Aug 2015 Active, not recruiting --> Completed | N=90 --> 58 | Trial primary completion date: Jun 2009 --> Jun 2007
- | fluconazole oral / Generic mfg.
Trial completion: Fluconazole in Preventing Mucositis in Patients Undergoing Radiation Therapy for Head and Neck Cancer (clinicaltrials.gov) - Dec 14, 2016
P2/3, N=0, Completed, Sponsor: University of Miami
Active, not recruiting --> Completed | N=90 --> 58 | Trial primary completion date: Jun 2009 --> Jun 2007 Not yet recruiting --> Completed
- Trial completion, Trial primary completion date: Feasibility Study of Low Level Light Therapy for Prevention of Oropharyngeal Mucositis in Pediatric Transplants Patients (clinicaltrials.gov) - Nov 23, 2016
P=N/A, N=13, Completed, Sponsor: Dana-Farber Cancer Institute
Not yet recruiting --> Completed Active, not recruiting --> Completed | Trial primary completion date: Sep 2017 --> Nov 2015
- ||| Enrollment closed, Trial primary completion date: Safety and Efficacy of IZN-6N4 Oral Rinse for the Prevention of Oral Mucositis in Patients With Head and Neck Cancer (clinicaltrials.gov) - Nov 15, 2016
P2, N=110, Active, not recruiting, Sponsor: Izun Pharma Ltd
Active, not recruiting --> Completed | Trial primary completion date: Sep 2017 --> Nov 2015 Recruiting --> Active, not recruiting | Trial primary completion date: Jun 2016 --> Jan 2017
- Enrollment change, Trial withdrawal: A Phase III Study of Efficacy of Lactobacillus CD2 Lozenges in Preventing High-Dose Chemotherapy Induced Oral Mucositis in Patients Undergoing Myeloablative Hematopoietic Stem Cell Transplantation (clinicaltrials.gov) - Nov 9, 2016
P3, N=0, Withdrawn, Sponsor: All India Institute of Medical Sciences, New Delhi
Recruiting --> Active, not recruiting | Trial primary completion date: Jun 2016 --> Jan 2017 N=108 --> 0 | Not yet recruiting --> Withdrawn
- || brilacidin (PMX-30063) / Innovation Pharma
Trial primary completion date: Study of the Effects of Brilacidin Oral Rinse on Radiation-induced Oral Mucositis in Patients With Head and Neck Cancer (clinicaltrials.gov) - Oct 31, 2016
P2, N=60, Recruiting, Sponsor: Cellceutix Corporation
N=108 --> 0 | Not yet recruiting --> Withdrawn Trial primary completion date: Jun 2016 --> Dec 2017
- Trial completion, Trial primary completion date: Cryotherapy for Prevention of Oral Mucositis in Children Undergoing Hematopoietic Stem Cell Transplantation (clinicaltrials.gov) - Oct 27, 2016
P=N/A, N=53, Completed, Sponsor: Uppsala University
Trial primary completion date: Jun 2016 --> Dec 2017 Trial primary completion date: Jun 2017 --> Jun 2016 | Recruiting --> Completed
- Enrollment closed, Enrollment change: The FOCCUS Study: "Focusing on Cancers Chemotherapys' Untreated Symptoms" (clinicaltrials.gov) - Oct 20, 2016
P=N/A, N=248, Active, not recruiting, Sponsor: Royal Marsden NHS Foundation Trust
Trial primary completion date: Jun 2017 --> Jun 2016 | Recruiting --> Completed Recruiting --> Active, not recruiting | N=500 --> 248
- | avasopasem manganese (GC4419) / Galera Therap
Trial completion, Combination therapy: A Phase 1 Dose Escalation Study of GC4419 in Combination With Chemoradiation for Squamous Cell Cancer of the Head & Neck (clinicaltrials.gov) - Sep 22, 2016
P1, N=30, Completed, Sponsor: Galera Therapeutics, Inc.
Recruiting --> Active, not recruiting | N=500 --> 248 Active, not recruiting --> Completed
- ||| Enrollment closed: ROSAM: Role of SAMITAL (clinicaltrials.gov) - Sep 19, 2016
P2, N=120, Active, not recruiting, Sponsor: Istituto Oncologico Veneto IRCCS
Active, not recruiting --> Completed Recruiting --> Active, not recruiting
- Trial completion: Non Surgical Treatment of Periimplantitis (clinicaltrials.gov) - Sep 2, 2016
P4, N=20, Completed, Sponsor: Proed
Recruiting --> Active, not recruiting Recruiting --> Completed
- Trial completion, Enrollment change, Trial primary completion date: Local Anesthetic Treatment of Oral Pain in Patients With Mucositis (clinicaltrials.gov) - Aug 16, 2016
P2, N=70, Completed, Sponsor: Hvidovre University Hospital
Recruiting --> Completed Recruiting --> Completed | N=40 --> 70 | Trial primary completion date: Aug 2015 --> Dec 2015
- Enrollment change: Therapies for Salivary Flux Stimulation in Patients Transplanted With Hematopoietic Stem Cells (clinicaltrials.gov) - Aug 10, 2016
P1, N=0, Withdrawn, Sponsor: Federal University of Minas Gerais
Recruiting --> Completed | N=40 --> 70 | Trial primary completion date: Aug 2015 --> Dec 2015 N=60 --> 0
- Trial primary completion date: Honey in Chronic Immune Thrombocytopenia (clinicaltrials.gov) - Jul 19, 2016
P2, N=30, Suspended, Sponsor: mamdouh abdulmaksoud abdulrhman
N=60 --> 0 Trial primary completion date: Jan 2016 --> Jan 2017
- ||||||| Kepivance (palifermin) / SOBI, Amgen
Trial completion, Metastases: A Study of Palifermin for the Reduction of Oral Mucositis in Subjects With Advanced Head and Neck Cancer (clinicaltrials.gov) - Jul 18, 2016
P3, N=241, Completed, Sponsor: Amgen
Trial primary completion date: Jan 2016 --> Jan 2017 Active, not recruiting --> Completed
- | Trial completion: Capsaicin Lozenges in Treating Patients With Mucositis Caused by Radiation Therapy (clinicaltrials.gov) - Jul 11, 2016
P3, N=18, Completed, Sponsor: Alliance for Clinical Trials in Oncology
Active, not recruiting --> Completed No longer recruiting --> Completed
- ||| Trial completion, Enrollment change, Trial primary completion date: Efficacy of MUCIPLIQ on the Incidence of Radio-chemotherapy-induced Mucositis in Patients Suffering From Oral Cancer (clinicaltrials.gov) - May 5, 2016
P=N/A, N=136, Completed, Sponsor: Organ, Tissue, Regeneration, Repair and Replacement
No longer recruiting --> Completed Recruiting --> Completed | N=105 --> 136 | Trial primary completion date: May 2015 --> Jan 2015
- NN1213 / Novo Nordisk
Trial completion: Safety and Efficacy of CG53135-05 in the Prevention of Oral Mucositis in Patients Receiving Bone Marrow Transplant (clinicaltrials.gov) - Mar 13, 2016
P2, N=0, Completed, Sponsor: CuraGen Corporation
Recruiting --> Completed | N=105 --> 136 | Trial primary completion date: May 2015 --> Jan 2015 No longer recruiting --> Completed
- | Kepivance (palifermin) / SOBI, Amgen
Trial completion: Pharmacokinetic Study of Palifermin in Subjects Receiving Radiation Therapy and Chemotherapy Followed by Blood Stem Cell Support (clinicaltrials.gov) - Feb 27, 2016
P1, N=25, Completed, Sponsor: Swedish Orphan Biovitrum
No longer recruiting --> Completed Recruiting --> Completed
- ||||||| NN1213 / Novo Nordisk
Trial completion: Safety & Efficacy Study of Benzydamine Oral Rinse for the Treatment of Oral Mucositis (Mouth Sores) Resulting From Radiation Therapy for Cancer of the Oral Cavity, Oropharynx, or Nasopharynx (clinicaltrials.gov) - Feb 27, 2016
P3, N=605, Completed, Sponsor: McNeil Consumer & Specialty Pharmaceuticals, a Division of McNeil-PPC, Inc.
Recruiting --> Completed Terminated --> Completed
- Enrollment change: Nutritional Risk and Mucositis in Patients With Head and Neck Carcinoma Receiving Chemoradiation (clinicaltrials.gov) - Feb 9, 2016
P=N/A, N=37, Completed, Sponsor: University of Arkansas
Terminated --> Completed N=60 --> 37
- acetylcysteine solution / Generic mfg.
Enrollment closed, Enrollment change: Acetylcysteine Rinse in Reducing Saliva Thickness and Mucositis in Patients With Head and Neck Cancer Undergoing Radiation Therapy (clinicaltrials.gov) - Feb 5, 2016
P=N/A, N=18, Active, not recruiting, Sponsor: Mayo Clinic
N=60 --> 37 Recruiting --> Active, not recruiting | N=36 --> 18
- ||||||| Trial completion: RadioHum: Radiotherapy With Humidification in Head And Neck Cancer (clinicaltrials.gov) - Jan 20, 2016
P3, N=210, Completed, Sponsor: Trans-Tasman Radiation Oncology Group (TROG)
Recruiting --> Active, not recruiting | N=36 --> 18 Active, not recruiting --> Completed
- everolimus / Generic mfg.
Enrollment change, Trial termination, Trial primary completion date: Pharmacokinetically Guided Everolimus in Patients With Breast Cancer, Pancreatic Neuroendocrine Tumors, or Kidney Cancer (clinicaltrials.gov) - Jan 15, 2016
P2, N=2, Terminated, Sponsor: Emory University
Active, not recruiting --> Completed N=26 --> 2 | Recruiting --> Terminated | Trial primary completion date: Oct 2016 --> Dec 2015; Slow accrual
- | NN1213 / Novo Nordisk
Trial completion: Traumeel (clinicaltrials.gov) - Jan 5, 2016
P=N/A, N=195, Completed, Sponsor: Children's Oncology Group
N=26 --> 2 | Recruiting --> Terminated | Trial primary completion date: Oct 2016 --> Dec 2015; Slow accrual Active, not recruiting --> Completed
- Trial primary completion date: Honey in Chronic Immune Thrombocytopenia (clinicaltrials.gov) - Dec 29, 2015
P2, N=30, Suspended, Sponsor: mamdouh abdulmaksoud abdulrhman
Active, not recruiting --> Completed Trial primary completion date: Nov 2014 --> Jan 2016
- Trial primary completion date: Cryotherapy for Prevention of Oral Mucositis in Children Undergoing Hematopoietic Stem Cell Transplantation (clinicaltrials.gov) - Dec 6, 2015
P=N/A, N=50, Recruiting, Sponsor: Uppsala University
Trial primary completion date: Nov 2014 --> Jan 2016 Trial primary completion date: Jun 2015 --> Jun 2017
- Trial primary completion date: Analgesic Effects of Topical Ketamine Mouthwash in Patients Receiving Chemoradiation or Radiotherapy for Head & Neck Cancer (clinicaltrials.gov) - Nov 15, 2015
P2, N=10, Recruiting, Sponsor: Dartmouth-Hitchcock Medical Center
Trial primary completion date: Jun 2015 --> Jun 2017 Trial primary completion date: Jan 2016 --> Jan 2017