Esophageal Diseases
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  • ||||||||||  Trial completion date, Trial primary completion date:  Narrow Band Imaging Project on Barrett's Esophagus (clinicaltrials.gov) -  Mar 16, 2023   
    P=N/A,  N=50, Suspended, 
    Trial completion date: Jan 2028 --> Jan 2030 | Trial primary completion date: Jan 2025 --> Jan 2030 Trial completion date: Dec 2019 --> Dec 2025 | Trial primary completion date: Dec 2019 --> Dec 2024
  • ||||||||||  Enrollment change, Trial termination, Trial primary completion date:  TECR & ECM Placement for Esophageal High Grade Dysplasia (clinicaltrials.gov) -  Mar 19, 2019   
    P=N/A,  N=1, Terminated, 
    Recruiting --> Completed | N=30 --> 51 N=10 --> 1 | Recruiting --> Terminated | Trial primary completion date: Mar 2017 --> Mar 2018; Serious Adverse Event of Patient who completed study and follow-up.
  • ||||||||||  Trial completion, Trial completion date:  Validation of the French Version of the Sydney Swallow Questionnaire in Patients With Neuromuscular Diseases (clinicaltrials.gov) -  Mar 19, 2019   
    P=N/A,  N=250, Completed, 
    N=10 --> 1 | Recruiting --> Terminated | Trial primary completion date: Mar 2017 --> Mar 2018; Serious Adverse Event of Patient who completed study and follow-up. Recruiting --> Completed | Trial completion date: Jul 2018 --> Oct 2018
  • ||||||||||  Enrollment change, Trial withdrawal, Trial primary completion date:  Head and Neck Cancer Treatment Related Dysphagia (clinicaltrials.gov) -  Mar 18, 2019   
    P=N/A,  N=0, Withdrawn, 
    Recruiting --> Completed | N=51 --> 81 N=250 --> 0 | Not yet recruiting --> Withdrawn | Trial primary completion date: Mar 2019 --> Jun 2017
  • ||||||||||  Enrollment change, Trial completion date, Trial termination, Trial primary completion date:  Early Integration of Palliative Care in Esophageal Cancer Patients (clinicaltrials.gov) -  Mar 14, 2019   
    P=N/A,  N=12, Terminated, 
    Active, not recruiting --> Completed | Trial completion date: May 2020 --> Feb 2019 N=120 --> 12 | Trial completion date: Dec 2019 --> Mar 2019 | Recruiting --> Terminated | Trial primary completion date: Dec 2019 --> Mar 2019; Study futility with regards to recruitment
  • ||||||||||  Enrollment change, Trial completion date, Trial termination, Trial primary completion date:  HX4 SD: Tumor Hypoxia With HX4 PET in Several Diseases (clinicaltrials.gov) -  Mar 8, 2019   
    P2,  N=1, Terminated, 
    N=120 --> 20 | Recruiting --> Completed N=120 --> 1 | Trial completion date: Jun 2020 --> May 2017 | Recruiting --> Terminated | Trial primary completion date: Dec 2019 --> May 2017; patients did not want to participate
  • ||||||||||  Trial completion, Trial completion date, Trial primary completion date:  Human (Autologous) Oral Mucosal Cell Sheet Transplantation After ESD in Patients With Superficial Esophageal Cancer (clinicaltrials.gov) -  Mar 7, 2019   
    P3,  N=10, Completed, 
    N=120 --> 1 | Trial completion date: Jun 2020 --> May 2017 | Recruiting --> Terminated | Trial primary completion date: Dec 2019 --> May 2017; patients did not want to participate Recruiting --> Completed | Trial completion date: Mar 2018 --> Feb 2019 | Trial primary completion date: Mar 2018 --> Feb 2019
  • ||||||||||  Preclinical, Enrollment change, Trial completion date, Trial termination:  In Vivo Anatomy, Physiology, Mechanics and Function of the Lower Esophageal Sphincter (clinicaltrials.gov) -  Feb 22, 2019   
    P=N/A,  N=4, Terminated, 
    Recruiting --> Completed N=100 --> 4 | Trial completion date: Dec 2018 --> Feb 2017 | Recruiting --> Terminated; Was not able to recruit the total anticipated number of subjects
  • ||||||||||  Trial completion, Trial primary completion date:  a4b7 Integrin in Eosinophilic Esophagitis (clinicaltrials.gov) -  Feb 21, 2019   
    P=N/A,  N=16, Completed, 
    N=100 --> 4 | Trial completion date: Dec 2018 --> Feb 2017 | Recruiting --> Terminated; Was not able to recruit the total anticipated number of subjects Active, not recruiting --> Completed | Trial primary completion date: Jul 2018 --> Dec 2018
  • ||||||||||  Trial completion:  Recurrent Respiratory Papillomatosis and Extraesophageal Reflux (clinicaltrials.gov) -  Feb 20, 2019   
    P=N/A,  N=60, Completed, 
    Active, not recruiting --> Completed | Trial primary completion date: Jul 2018 --> Dec 2018 Recruiting --> Completed
  • ||||||||||  Gastrocrom (cromolyn) / Viatris
    Trial termination:  Cromolyn Detection of Silent Aspiration (clinicaltrials.gov) -  Feb 16, 2019   
    P1,  N=16, Terminated, 
    Recruiting --> Completed Recruiting --> Terminated; Difficulty recruiting; Funding ended; interim analysis provided sufficient data for interpretation.
  • ||||||||||  Teysuno (gimeracil/oteracil/tegafur) / Nordic Group, Otsuka
    Trial completion, Combination therapy:  Study of S-1 in Combination With Radiotherapy in Esophageal Cancer (clinicaltrials.gov) -  Feb 16, 2019   
    P2,  N=105, Completed, 
    Recruiting --> Terminated; Difficulty recruiting; Funding ended; interim analysis provided sufficient data for interpretation. Active, not recruiting --> Completed
  • ||||||||||  Trial completion, Enrollment change, Trial completion date, Trial primary completion date:  Non-invasive Prediction of Esophageal Varices in Liver Cirrhosis: A Multicenter Observational Study (clinicaltrials.gov) -  Feb 4, 2019   
    P=N/A,  N=363, Completed, 
    Recruiting --> Completed Recruiting --> Completed | N=1000 --> 363 | Trial completion date: Jun 2019 --> Dec 2018 | Trial primary completion date: Jun 2019 --> Dec 2018
  • ||||||||||  esomeprazole / Generic mfg.
    Trial completion, Trial completion date:  BRAVO Study for Functional Dyspepsia (clinicaltrials.gov) -  Jan 31, 2019   
    P4,  N=130, Completed, 
    Recruiting --> Completed | N=1000 --> 363 | Trial completion date: Jun 2019 --> Dec 2018 | Trial primary completion date: Jun 2019 --> Dec 2018 Recruiting --> Completed | Trial completion date: Dec 2017 --> Jul 2018
  • ||||||||||  Trial completion:  NUTRIENTII: Nutritional Route In Esophageal Resection Trial II (clinicaltrials.gov) -  Jan 31, 2019   
    P=N/A,  N=148, Completed, 
    Recruiting --> Completed | Trial completion date: Dec 2017 --> Jul 2018 Active, not recruiting --> Completed
  • ||||||||||  Biomarker, Trial completion, Enrollment change, Trial completion date, Trial primary completion date:  Eosinophil β1 Integrin Activation as a Biomarker for Eosinophilic Esophagitis (clinicaltrials.gov) -  Jan 30, 2019   
    P=N/A,  N=28, Completed, 
    Active, not recruiting --> Completed Recruiting --> Completed | N=50 --> 28 | Trial completion date: May 2018 --> Dec 2018 | Trial primary completion date: May 2018 --> Dec 2018
  • ||||||||||  Trial completion, Trial completion date:  SIRUP: Stretta In Reflux Uncontrolled by IPP (clinicaltrials.gov) -  Jan 29, 2019   
    P=N/A,  N=62, Completed, 
    Recruiting --> Completed | N=50 --> 28 | Trial completion date: May 2018 --> Dec 2018 | Trial primary completion date: May 2018 --> Dec 2018 Recruiting --> Completed | Trial completion date: May 2019 --> Nov 2018
  • ||||||||||  cisplatin / Generic mfg.
    Trial termination, Biopsy:  CHFR Methylation Status Esophageal Cancer Study (clinicaltrials.gov) -  Jan 25, 2019   
    P2,  N=31, Terminated, 
    Recruiting --> Completed | N=120 --> 35 Active, not recruiting --> Terminated; Study stopped due to early stopping rule
  • ||||||||||  Trial completion date, Trial suspension, Trial primary completion date:  Narrow Band Imaging Project on Barrett's Esophagus (clinicaltrials.gov) -  Jan 25, 2019   
    P=N/A,  N=50, Suspended, 
    Active, not recruiting --> Terminated; Study stopped due to early stopping rule Trial completion date: Dec 2018 --> Dec 2019 | Recruiting --> Suspended | Trial primary completion date: Dec 2018 --> Dec 2019
  • ||||||||||  5-fluorouracil / Generic mfg., cisplatin / Generic mfg., docetaxel / Generic mfg.
    Biomarker, Trial completion, Enrollment change, Trial completion date, Metastases:  Phase II Study Using CHFR Methylation Status in Patients With Metastatic Esophageal, Gastroesophageal, Gastric Cancer. (clinicaltrials.gov) -  Jan 25, 2019   
    P2,  N=21, Completed, 
    Trial completion date: Dec 2018 --> Dec 2019 | Recruiting --> Suspended | Trial primary completion date: Dec 2018 --> Dec 2019 Recruiting --> Completed | N=127 --> 21 | Trial completion date: Nov 2019 --> Apr 2017
  • ||||||||||  Trial completion, Trial completion date, Trial primary completion date:  Tethered Capsule Endoscope in Screening Patients With Barrett Esophagus (clinicaltrials.gov) -  Jan 23, 2019   
    P=N/A,  N=1, Completed, 
    Recruiting --> Completed | N=127 --> 21 | Trial completion date: Nov 2019 --> Apr 2017 Withdrawn --> Completed | Trial completion date: Jul 2018 --> Aug 2017 | Trial primary completion date: Jul 2018 --> Aug 2017
  • ||||||||||  Trial completion, Enrollment change, Trial completion date, Trial primary completion date:  A Validation Study of the Dx-pH Probe in Children for the Detection of Extra-oesophageal Reflux (clinicaltrials.gov) -  Jan 19, 2019   
    P=N/A,  N=16, Completed, 
    Recruiting --> Completed | Trial completion date: Sep 2018 --> Dec 2018 | Trial primary completion date: Aug 2018 --> Dec 2018 Active, not recruiting --> Completed | N=30 --> 16 | Trial completion date: Jan 2016 --> Apr 2017 | Trial primary completion date: Jan 2016 --> Apr 2017
  • ||||||||||  Trial completion, Trial completion date, Trial primary completion date:  Secondary Prophylaxis of Gastric Variceal Bleed (clinicaltrials.gov) -  Jan 8, 2019   
    P=N/A,  N=64, Completed, 
    N=50 --> 24 | Trial completion date: Jan 2021 --> Nov 2018 | Recruiting --> Terminated; Study terminated due to low accrual. Recruiting --> Completed | Trial completion date: Jun 2018 --> Jan 2019 | Trial primary completion date: Jun 2018 --> Feb 2018
  • ||||||||||  Movantik (naloxegol) / AstraZeneca, RedHill, Kyowa Kirin
    Enrollment change, Trial completion date, Trial termination, Trial primary completion date:  Movantik for Opioid-Related Esophageal Disorders (clinicaltrials.gov) -  Dec 24, 2018   
    P2,  N=2, Terminated, 
    Recruiting --> Completed | Trial completion date: Jun 2018 --> Jan 2019 | Trial primary completion date: Jun 2018 --> Feb 2018 N=50 --> 2 | Trial completion date: Jan 2020 --> Oct 2018 | Recruiting --> Terminated | Trial primary completion date: Jan 2019 --> Oct 2018; Investigator left Institution
  • ||||||||||  Trial completion, Phase classification, Trial completion date:  Study to Image the Esophagus Using the OFDI Capsule (clinicaltrials.gov) -  Dec 5, 2018   
    P=N/A,  N=54, Completed, 
    N=36 --> 19 Recruiting --> Completed | Phase classification: P1 --> PN/A | Trial completion date: Oct 2018 --> Jul 2016
  • ||||||||||  lansoprazole / Generic mfg., omeprazole / Generic mfg., esomeprazole / Generic mfg.
    Biomarker, Trial completion:  Implementation of PPI Medication PGX Testing (clinicaltrials.gov) -  Nov 21, 2018   
    P4,  N=28, Completed, 
    Trial completion date: Jan 2020 --> Jan 2024 | Trial primary completion date: Oct 2019 --> Oct 2023 Active, not recruiting --> Completed