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128 Companies |
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121 Products |
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121 Products |
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104 Mechanisms of Action |
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7 Trials |
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1812 News |
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- | simvastatin / Generic mfg., carvedilol / Generic mfg.
Trial completion, Trial primary completion date: To Compare the Efficacy and Safety of Carvedilol With or Without Simvastatin in Patients With Portal Hypertension and Esophageal Varices. (clinicaltrials.gov) - Nov 21, 2017
P=N/A, N=220, Completed, Sponsor: Institute of Liver and Biliary Sciences, India
Recruiting --> Completed | Trial primary completion date: Oct 2017 --> Jan 2017
- | Trial completion: Value of Patch Testing in Direct Diet Therapy for Eosinophilic Esophagitis (clinicaltrials.gov) - Nov 20, 2017
P=N/A, N=8, Completed, Sponsor: Mayo Clinic
Recruiting --> Completed | Trial primary completion date: Oct 2017 --> Jan 2017 Active, not recruiting --> Completed
- | famotidine / Generic mfg., ranitidine hydrochloride / Generic mfg.
Enrollment change, Trial withdrawal: In Infants With Laryngomalacia, Does Acid-Blocking Medication Improve Respiratory Symptoms? (clinicaltrials.gov) - Nov 18, 2017
P=N/A, N=0, Withdrawn, Sponsor: Stanford University
Active, not recruiting --> Completed N=106 --> 0 | Recruiting --> Withdrawn
- | Trial withdrawal: Tethered Capsule Endoscope in Screening Patients With Barrett Esophagus (clinicaltrials.gov) - Nov 18, 2017
P=N/A, N=0, Withdrawn, Sponsor: University of Washington
N=106 --> 0 | Recruiting --> Withdrawn Recruiting --> Withdrawn
- | dexlansoprazole / Generic mfg.
Trial termination, Trial primary completion date: Efficacy and Safety of Dexlansoprazole in Healing and Maintaining Healing of Erosive Esophagitis (clinicaltrials.gov) - Nov 17, 2017
P3, N=61, Terminated, Sponsor: Takeda
Recruiting --> Withdrawn Active, not recruiting --> Terminated | Trial primary completion date: Jun 2018 --> Oct 2017; Compound is not expected to change the current treatment practice or fill significant clinical need for patients in China over currently available EE agents.
- ||| Trial completion: SWAN: Study on the Tolerance and Efficacy of a New Anti-regurgitation Formula (PC-2016-01) (clinicaltrials.gov) - Nov 14, 2017
P=N/A, N=100, Completed, Sponsor: United Pharmaceuticals
Active, not recruiting --> Terminated | Trial primary completion date: Jun 2018 --> Oct 2017; Compound is not expected to change the current treatment practice or fill significant clinical need for patients in China over currently available EE agents. Active, not recruiting --> Completed
- | Trial completion, Trial primary completion date: Influence of Intrapulmonary Percussive Ventilation (IPV) on Gastro-oesophageal Reflux (GOR). (clinicaltrials.gov) - Nov 8, 2017
P=N/A, N=50, Completed, Sponsor: Vrije Universiteit Brussel
Active, not recruiting --> Completed Recruiting --> Completed | Trial primary completion date: Oct 2018 --> Oct 2017
- | davamotecan pegadexamer (EP0057) / Ellipses Pharma
Phase classification, Surgery, Metastases: Pilot Trial of CRLX101 in Treatment of Patients With Advanced or Metastatic Stomach, Gastroesophageal, or Esophageal Cancer That Cannot be Removed by Surgery (clinicaltrials.gov) - Nov 8, 2017
P2, N=10, Completed, Sponsor: City of Hope Medical Center
Recruiting --> Completed | Trial primary completion date: Oct 2018 --> Oct 2017 Phase classification: P=N/A --> P2
- | Trial completion, Enrollment change: Efficacy of Natural Ingredient to Improve the Swallowing Response of Patients With Oropharyngeal Dysphagia (clinicaltrials.gov) - Oct 26, 2017
P=N/A, N=104, Completed, Sponsor: Nestl
Phase classification: P=N/A --> P2 Recruiting --> Completed | N=84 --> 104
- | Trial completion, Enrollment change: Cardiaplication: A Novel Antireflux Operation (clinicaltrials.gov) - Oct 24, 2017
P=N/A, N=8, Completed, Sponsor: Emory University
Recruiting --> Completed | N=84 --> 104 Active, not recruiting --> Completed | N=20 --> 8
- | cisplatin / Generic mfg., paclitaxel / Generic mfg.
Trial completion: Postoperative Chemoradiation in Patients With Node-positive Esophageal Squamous Cell Carcinoma (clinicaltrials.gov) - Oct 24, 2017
P1/2, N=33, Completed, Sponsor: Chinese Academy of Medical Sciences
Active, not recruiting --> Completed | N=20 --> 8 Recruiting --> Completed
- | Trial primary completion date: POETRI: POsitioning for Esophageal Cancer Resection (clinicaltrials.gov) - Oct 20, 2017
P=N/A, N=47, Terminated, Sponsor: Technische Universit
Recruiting --> Completed Trial primary completion date: Jun 2017 --> Feb 2017
- | Enrollment change: Application of a Novel Allergen-Specific Immune Signature Directed Approach to Dietary Elimination Therapy in Patients With Eosinophilic Esophagitis (IDiET) (clinicaltrials.gov) - Oct 19, 2017
P=N/A, N=30, Enrolling by invitation, Sponsor: University of North Carolina, Chapel Hill
Trial primary completion date: Jun 2017 --> Feb 2017 N=16 --> 30
- | AMG 337 / ImmunityBio, Amgen
Phase classification, Enrollment change, Trial withdrawal, Trial primary completion date, Metastases: C-Met Inhibitor AMG 337, Oxaliplatin, Leucovorin Calcium, and Fluorouracil in Treating Patients With Advanced Stomach or Esophageal Cancer (clinicaltrials.gov) - Oct 19, 2017
P2, N=0, Withdrawn, Sponsor: Eastern Cooperative Oncology Group
N=16 --> 30 Phase classification: P1/2 --> P2 | N=308 --> 0 | Not yet recruiting --> Withdrawn | Trial primary completion date: Jun 2016 --> Mar 2018
- Zykadia (ceritinib) / Novartis
Trial primary completion date: Study of Oral Ceritinib in Patients With ALK and ROS1 Activated Gastrointestinal Malignancies (clinicaltrials.gov) - Oct 18, 2017
P2, N=30, Recruiting, Sponsor: Criterium, Inc.
Phase classification: P1/2 --> P2 | N=308 --> 0 | Not yet recruiting --> Withdrawn | Trial primary completion date: Jun 2016 --> Mar 2018 Trial primary completion date: Aug 2017 --> Dec 2017
- Trial primary completion date: RELIEF Europe Study (clinicaltrials.gov) - Oct 16, 2017
P=N/A, N=7, Terminated, Sponsor: Torax Medical Incorporated
Trial primary completion date: Aug 2017 --> Dec 2017 Trial primary completion date: Aug 2017 --> Feb 2017
- | Trial primary completion date: [Impedance Measurement for Non-Erosive Reflux Disease (clinicaltrials.gov) - Oct 11, 2017
P=N/A, N=40, Enrolling by invitation, Sponsor: Mayo Clinic
Trial primary completion date: Aug 2017 --> Feb 2017 Trial primary completion date: Aug 2017 --> Aug 2018
- | omeprazole / Generic mfg.
Enrollment change, Trial withdrawal: CYP2C19 Genotype Predictor of Gastric Acid Suppression (clinicaltrials.gov) - Oct 11, 2017
P, N=0, Withdrawn, Sponsor: Mayo Clinic
Trial primary completion date: Aug 2017 --> Aug 2018 N=100 --> 0 | Active, not recruiting --> Withdrawn
- | Carafate (sucralfate) / AbbVie
Trial completion: EoE: The Effect of Sucralfate Slurry in Patients With Eosinophilic Esophagitis (clinicaltrials.gov) - Oct 11, 2017
P, N=3, Completed, Sponsor: Mayo Clinic
N=100 --> 0 | Active, not recruiting --> Withdrawn Active, not recruiting --> Completed
- Enrollment change, Trial termination, Trial primary completion date: Compound Sodium Alginate Oral Suspension Sachet 4-hour Esophageal pH Study in GERD Patients (clinicaltrials.gov) - Oct 6, 2017
P3, N=16, Terminated, Sponsor: Reckitt Benckiser Healthcare (UK) Limited
Active, not recruiting --> Completed N=88 --> 16 | Recruiting --> Terminated | Trial primary completion date: Sep 2017 --> Mar 2017; Problems with recruitment
- | Trial primary completion date: 4-Dimensional CT Derived Ventilation Versus SPECT Aerosol Ventilation in Patients With Thoracic Malignancies (clinicaltrials.gov) - Oct 5, 2017
P2, N=36, Active, not recruiting, Sponsor: M.D. Anderson Cancer Center
N=88 --> 16 | Recruiting --> Terminated | Trial primary completion date: Sep 2017 --> Mar 2017; Problems with recruitment Trial primary completion date: Nov 2018 --> Aug 2019
- | Trial completion, Enrollment change: Reduction of Aspiration Through Cohesive Thin Liquids (CTL) in Patients With Mild Oropharyngeal Dysphagia (clinicaltrials.gov) - Oct 5, 2017
P=N/A, N=35, Completed, Sponsor: Nestl
Trial primary completion date: Nov 2018 --> Aug 2019 Recruiting --> Completed | N=47 --> 35
- | Trial completion, Enrollment change, Trial primary completion date, FDG PET: 4D FDG PET in Esophageal Cancer (clinicaltrials.gov) - Sep 28, 2017
P=N/A, N=54, Completed, Sponsor: The Netherlands Cancer Institute
Recruiting --> Completed | N=47 --> 35 Recruiting --> Completed | N=30 --> 54 | Trial primary completion date: Dec 2017 --> May 2017
- | Enrollment change, Trial termination, Trial primary completion date: Early Prediction of Pathology Response of Chemoradiotherapy With FLT PET (clinicaltrials.gov) - Sep 26, 2017
P=N/A, N=6, Terminated, Sponsor: Columbia University
Recruiting --> Completed | N=30 --> 54 | Trial primary completion date: Dec 2017 --> May 2017 N=100 --> 6 | Recruiting --> Terminated | Trial primary completion date: Aug 2012 --> Feb 2013; Lack of funding
- | Trial initiation date: Effect of Different Viscous Foods and Liquids on Swallowing Sounds (clinicaltrials.gov) - Sep 25, 2017
P=N/A, N=38, Not yet recruiting, Sponsor: University of Nebraska
N=100 --> 6 | Recruiting --> Terminated | Trial primary completion date: Aug 2012 --> Feb 2013; Lack of funding Initiation date: Jun 2017 --> Sep 2018
- | Preclinical, Trial primary completion date: In Vivo Anatomy, Physiology, Mechanics and Function of the Lower Esophageal Sphincter (clinicaltrials.gov) - Sep 21, 2017
P=N/A, N=100, Recruiting, Sponsor: Northwell Health
Initiation date: Jun 2017 --> Sep 2018 Trial primary completion date: Jun 2017 --> Jun 2018
- | cisplatin / Generic mfg., irinotecan / Generic mfg., celecoxib oral / Generic mfg.
Trial completion, Trial primary completion date, Surgery: Cisplatin, CPT-11 and Celecoxib With Radiation Therapy and Surgery for Operable Esophageal Cancer (clinicaltrials.gov) - Sep 20, 2017
P2, N=35, Completed, Sponsor: Dana-Farber Cancer Institute
Trial primary completion date: Jun 2017 --> Jun 2018 Active, not recruiting --> Completed | Trial primary completion date: Nov 2003 --> Aug 2004
- | Trial primary completion date: Pediatric Dysphagia Outcomes After Injection Laryngoplasty for Type I Laryngeal Cleft (clinicaltrials.gov) - Sep 20, 2017
P4, N=50, Completed, Sponsor: Oregon Health and Science University
Active, not recruiting --> Completed | Trial primary completion date: Nov 2003 --> Aug 2004 Trial primary completion date: May 2013 --> May 2015
- | Varithena (polidocanol injectable foam) / Boston Scientific
Enrollment change, Trial withdrawal, Trial primary completion date: Effect of PEM Treatment of Superficial Axial and Tributary Vein Reflux on Improvement of Wound Healing in VLUs (clinicaltrials.gov) - Sep 15, 2017
P4, N=0, Withdrawn, Sponsor: OhioHealth
Trial primary completion date: May 2013 --> May 2015 N=60 --> 0 | Recruiting --> Withdrawn | Trial primary completion date: Apr 2018 --> Sep 2017
- |||| Teysuno (gimeracil/oteracil/tegafur) / Nordic Group, Otsuka
Trial primary completion date, Metastases: S-1+Oxaliplatin vs.S-1+Cisplatin First-line Treatment of Advanced or Recurrent Non-intestinal Type Gastric Adenocarcinoma Patients (clinicaltrials.gov) - Sep 13, 2017
P3, N=446, Recruiting, Sponsor: Sun Yat-sen University
N=60 --> 0 | Recruiting --> Withdrawn | Trial primary completion date: Apr 2018 --> Sep 2017 Trial primary completion date: Mar 2017 --> Mar 2018
- ||||||| K-CAB Tab (tegoprazan) / RaQualia, Sebela
Trial completion: Study to Confirm the Safety and Efficacy of CJ-12420 in Patients With Erosive Esophagitis (clinicaltrials.gov) - Sep 12, 2017
P3, N=302, Completed, Sponsor: CJ HealthCare Corporation
Trial primary completion date: Mar 2017 --> Mar 2018 Recruiting --> Completed
- | Trial suspension, Trial primary completion date, HEOR: Quality of Life and Dysphagia Following Palliative Stenting in Esophageal Cancer (clinicaltrials.gov) - Sep 1, 2017
P=N/A, N=100, Suspended, Sponsor: Centre hospitalier de l'Université de Montréal (CHUM)
Recruiting --> Completed Recruiting --> Suspended | Trial primary completion date: Jun 2017 --> Jun 2019
- | Trial completion, Trial primary completion date: CT0046 Study: Balloon Dilation to Permit Complete Endoscopic Ultrasound Staging in Esophageal Cancer (clinicaltrials.gov) - Sep 1, 2017
P=N/A, N=41, Completed, Sponsor: Centre hospitalier de l'Université de Montréal (CHUM)
Recruiting --> Suspended | Trial primary completion date: Jun 2017 --> Jun 2019 Recruiting --> Completed | Trial primary completion date: Jan 2017 --> Jun 2017
- | Enrollment change, Trial termination, Trial primary completion date, Metastases: mEGA: Molecularly Tailored Therapy for Patients With Metastatic Cancer of the Esophagus and Stomach (clinicaltrials.gov) - Sep 1, 2017
P=N/A, N=13, Terminated, Sponsor: Georgetown University
Recruiting --> Completed | Trial primary completion date: Jan 2017 --> Jun 2017 N=20 --> 13 | Recruiting --> Terminated | Trial primary completion date: Dec 2017 --> Nov 2016; Issues with recruitment.
- | Trial primary completion date: Manuka Honey in Preventing Esophagitis-Related Pain in Patients Receiving Chemotherapy and Radiation Therapy For Lung Cancer (clinicaltrials.gov) - Aug 31, 2017
P2, N=163, Completed, Sponsor: Radiation Therapy Oncology Group
N=20 --> 13 | Recruiting --> Terminated | Trial primary completion date: Dec 2017 --> Nov 2016; Issues with recruitment. Trial primary completion date: Nov 2014 --> Feb 2014
- | Trial termination: ESOPRESSO: Role of Esophagectomy in Complete Responders to CCRT (clinicaltrials.gov) - Aug 29, 2017
P3, N=486, Terminated, Sponsor: Asan Medical Center
Trial primary completion date: Nov 2014 --> Feb 2014 Recruiting --> Terminated; slow recruitment
- ||||| dexlansoprazole / Generic mfg.
Enrollment closed, Enrollment change: Efficacy and Safety of Dexlansoprazole in Healing and Maintaining Healing of Erosive Esophagitis (clinicaltrials.gov) - Aug 29, 2017
P3, N=61, Active, not recruiting, Sponsor: Takeda
Recruiting --> Terminated; slow recruitment Recruiting --> Active, not recruiting | N=450 --> 61
- | Trial primary completion date: Tethered Capsule Endoscope in Screening Patients With Barrett Esophagus (clinicaltrials.gov) - Aug 28, 2017
P=N/A, N=5, Recruiting, Sponsor: University of Washington
Recruiting --> Active, not recruiting | N=450 --> 61 Trial primary completion date: Sep 2017 --> Jul 2018
- | Trial completion, Trial primary completion date, Surgery: Reducing Dysphagia Associated With Anterior Cervical Spine Surgery by Maintaining Low Endotracheal Tube Cuff Pressure (clinicaltrials.gov) - Aug 28, 2017
P=N/A, N=40, Completed, Sponsor: Lawson Health Research Institute
Trial primary completion date: Sep 2017 --> Jul 2018 Recruiting --> Completed | Trial primary completion date: Aug 2011 --> Jul 2013
- | 5-fluorouracil / Generic mfg., cisplatin / Generic mfg., epirubicin / Generic mfg.
Trial primary completion date, HEOR, Surgery: QUINTETT: Quality of Life in Neoadjuvant Versus Adjuvant Therapy of Esophageal Cancer Treatment Trial (clinicaltrials.gov) - Aug 25, 2017
P3, N=96, Recruiting, Sponsor: Richard Malthaner
Recruiting --> Completed | Trial primary completion date: Aug 2011 --> Jul 2013 Trial primary completion date: Apr 2017 --> Nov 2018
- | Derazol DDR (dexrabeprazole) / Neutec
Trial completion: The Effect of Dexrabeprazole on Intragastric and Intraesophageal Acidity (clinicaltrials.gov) - Aug 24, 2017
P4, N=12, Completed, Sponsor: Neutec Ar-Ge San ve Tic A.Ş
Trial primary completion date: Apr 2017 --> Nov 2018 Recruiting --> Completed
- | Enrollment closed: Comparison of the Effect of Rabeprazole 50 mg DDR Capsules and 20 mg Enteric-coated Tablets (clinicaltrials.gov) - Aug 24, 2017
P4, N=48, Active, not recruiting, Sponsor: Neutec Ar-Ge San ve Tic A.Ş
Recruiting --> Completed Not yet recruiting --> Active, not recruiting
- | carvedilol / Generic mfg., propranolol / Generic mfg.
Trial completion, Trial initiation date, Trial primary completion date: PREDESCI: Study on B-blockers to Prevent Decompensation of Cirrhosis With HTPortal (clinicaltrials.gov) - Aug 22, 2017
P4, N=201, Completed, Sponsor: Fundació Institut de Recerca de l'Hospital de la Santa Creu i Sant Pau
Not yet recruiting --> Active, not recruiting Recruiting --> Completed | Initiation date: Sep 2009 --> Jan 2010 | Trial primary completion date: Sep 2011 --> Jul 2015
- | Victoza (liraglutide) / Novo Nordisk, Lyxumia (lixisenatide) / Zealand Pharma, Sanofi
Trial primary completion date: Effects of Victoza (clinicaltrials.gov) - Aug 22, 2017
P1, N=72, Active, not recruiting, Sponsor: Profil Institut f
Recruiting --> Completed | Initiation date: Sep 2009 --> Jan 2010 | Trial primary completion date: Sep 2011 --> Jul 2015 Trial primary completion date: Jul 2017 --> Oct 2017
- | Trial completion, Trial primary completion date: PET/MRI-EC: PET-CT vs DWI-MRI in Response Evaluation in Esophageal Cancer (clinicaltrials.gov) - Aug 22, 2017
P=N/A, N=26, Completed, Sponsor: University Medical Center Groningen
Trial primary completion date: Jul 2017 --> Oct 2017 Recruiting --> Completed | Trial primary completion date: Jan 2018 --> Aug 2017
- | Trial completion: PETANC: Comparison of Tumor Glucose Metabolism Before and After Artificial Nutrition (clinicaltrials.gov) - Aug 21, 2017
P=N/A, N=20, Completed, Sponsor: Institut du Cancer de Montpellier - Val d'Aurelle
Recruiting --> Completed | Trial primary completion date: Jan 2018 --> Aug 2017 Recruiting --> Completed
- | Xifaxan (rifaximin) / Alfa Wassermann, Bausch Health
Enrollment change, Trial primary completion date: Rifaximin in Patients With Gastroesophageal Variceal Bleeding (clinicaltrials.gov) - Aug 21, 2017
P=N/A, N=60, Recruiting, Sponsor: Shanghai Zhongshan Hospital
Recruiting --> Completed N=50 --> 60 | Trial primary completion date: Jun 2017 --> Oct 2017
- | indomethacin / Generic mfg.
Trial completion, Enrollment change, Trial primary completion date, Combination therapy: PIFA: Phase I Platinum Based Chemotherapy Plus Indomethacin (clinicaltrials.gov) - Aug 18, 2017
P1, N=13, Completed, Sponsor: UMC Utrecht
N=50 --> 60 | Trial primary completion date: Jun 2017 --> Oct 2017 Recruiting --> Completed | N=18 --> 13 | Trial primary completion date: Dec 2018 --> Aug 2017
- | Trial completion, Enrollment change, Trial primary completion date: The Turkish Feeding/Swallowing Impact Survey (clinicaltrials.gov) - Aug 17, 2017
P=N/A, N=117, Completed, Sponsor: Hacettepe University
Recruiting --> Completed | N=18 --> 13 | Trial primary completion date: Dec 2018 --> Aug 2017 Recruiting --> Completed | N=150 --> 117 | Trial primary completion date: Nov 2017 --> May 2017
- | Trial completion, Enrollment change: Buspirone for Functional Dysphagia (clinicaltrials.gov) - Aug 11, 2017
P=N/A, N=10, Completed, Sponsor: The Cleveland Clinic
Recruiting --> Completed | N=150 --> 117 | Trial primary completion date: Nov 2017 --> May 2017 Enrolling by invitation --> Completed | N=20 --> 10