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128 Companies |
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121 Products |
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121 Products |
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104 Mechanisms of Action |
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7 Trials |
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1812 News |
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- sirolimus / Generic mfg.
Enrollment change: Vaccine Therapy With or Without Sirolimus in Treating Patients With NY-ESO-1 Expressing Solid Tumors (clinicaltrials.gov) - Oct 10, 2013
P1, N=30, Recruiting, Sponsor: Roswell Park Cancer Institute
N=20 --> 30
- Enrollment open, HEOR: Dysphagia Handicap Index: A Structured Translation From English to German (clinicaltrials.gov) - Oct 7, 2013
P=N/A, N=130, Recruiting, Sponsor: University of Zurich
N=20 --> 30 Not yet recruiting --> Recruiting
- | New P4 trial: Hypoallergenic Infant Formula Containing Starch and the Probiotic: Effect on Gastric Emptying (clinicaltrials.gov) - Oct 6, 2013
P4, N=132, Not yet recruiting, Sponsor: University of Bari
- New P2 trial: Botulinum Toxin Injection in Hypercontractile Esophagus (clinicaltrials.gov) - Oct 4, 2013
P2, N=28, Recruiting, Sponsor: Hospices Civils de Lyon
- MK-2206 / Merck (MSD), Herceptin (trastuzumab) / Roche
Trial termination, Combination therapy, Surgery, Metastases: Akt Inhibitor MK2206, Lapatinib Ditosylate, and Trastuzumab in Treating Patients With Locally Advanced or Metastatic HER2-Positive Breast , Gastric, or Gastroesophageal Cancer That Cannot Be Removed By Surgery (clinicaltrials.gov) - Sep 26, 2013
P1, N=60, Terminated, Sponsor: National Cancer Institute (NCI)
Not yet recruiting --> Recruiting Recruiting --> Terminated
- | Enrollment open: Gastroesophageal Reflux Treatment in Scleroderma (clinicaltrials.gov) - Sep 23, 2013
P3, N=250, Recruiting, Sponsor: Khon Kaen University
Recruiting --> Terminated Active, not recruiting --> Recruiting
- lansoprazole / Generic mfg.
New P1/2 trial: Lansoprazole in Preterm Infants With Gastroesophageal Reflux (GER) (clinicaltrials.gov) - Sep 18, 2013
P1/2, N=12, Active, not recruiting, Sponsor: Seoul National University Hospital
- | 5-fluorouracil / Generic mfg., cisplatin / Generic mfg.
Trial completion, Surgery: Surgery With or Without Chemotherapy in Treating Patients With Stage II or Stage III Cancer of the Esophagus (clinicaltrials.gov) - Sep 18, 2013
P3, N=240, Completed, Sponsor: European Institute of Oncology
Active, not recruiting --> Recruiting Active, not recruiting --> Completed
- Trial initiation date, HEOR: Quality of Life After Esophagectomy for Cancer - Step 2 (clinicaltrials.gov) - Sep 17, 2013
P=N/A, N=128, Recruiting, Sponsor: University of Padova
Active, not recruiting --> Completed Initiation date: Oct 2012 --> Jan 2013
- Trial initiation date, HEOR: Quality of Life After Esophagectomy for Cancer - Step 1 (clinicaltrials.gov) - Sep 17, 2013
P=N/A, N=128, Recruiting, Sponsor: University of Padova
Initiation date: Oct 2012 --> Jan 2013 Initiation date: Oct 2012 --> Jan 2013
- | Enrollment open: NewBreez Safety and Efficacy Evaluation (clinicaltrials.gov) - Sep 15, 2013
P2/3, N=20, Recruiting, Sponsor: ProTiP Medical
Initiation date: Oct 2012 --> Jan 2013 Not yet recruiting --> Recruiting
- esomeprazole / Generic mfg.
Enrollment open: PHARO: Benefit of Pharyngeal and Oesophageal pH-impedance of Patients With High Suspicion of Laryngopharyngeal Reflux (clinicaltrials.gov) - Sep 12, 2013
P=N/A, N=30, Recruiting, Sponsor: University Hospital, Bordeaux
Not yet recruiting --> Recruiting Not yet recruiting --> Recruiting
- lansoprazole / Generic mfg.
Trial completion: Lansoprazole in Preterm Infants With Reflux (clinicaltrials.gov) - Sep 10, 2013
P2, N=5, Completed, Sponsor: Seoul National University Hospital
Not yet recruiting --> Recruiting Recruiting --> Completed
- Biomarker, Enrollment closed: PMRR-NO: Pulmonary Metabolic Radiation Response Versus Exhaled Nitric Oxide (clinicaltrials.gov) - Sep 9, 2013
P2, N=150, Active, not recruiting, Sponsor: M.D. Anderson Cancer Center
Recruiting --> Completed Recruiting --> Active, not recruiting
- || Enrollment closed: Treatment of Extraesophageal Reflux With the Reza Band UES Assist Device (clinicaltrials.gov) - Sep 4, 2013
P=N/A, N=100, Active, not recruiting, Sponsor: Somna Therapeutics, L.L.C.
Recruiting --> Active, not recruiting Recruiting --> Active, not recruiting
- ||| Herceptin (trastuzumab) / Roche
Enrollment closed, Combination therapy, Metastases: HerFLOT: Explorative Phase II Study of Perioperative Treatment in Patients With Adenocarcinoma of the Gastroesophageal Junction or Stomach (clinicaltrials.gov) - Sep 4, 2013
P2, N=53, Active, not recruiting, Sponsor: AIO-Studien-gGmbH
Recruiting --> Active, not recruiting Recruiting --> Active, not recruiting
- Trial termination, Surgery: Perioperative Nutrition in Upper Gastrointestinal (GI) Cancer Surgery (clinicaltrials.gov) - Sep 3, 2013
P=N/A, N=43, Terminated, Sponsor: Dan Azagury
Recruiting --> Active, not recruiting Recruiting --> Terminated; Insufficient recruitment over time.
- Enrollment change, Surgery: Perioperative Nutrition in Upper Gastrointestinal (GI) Cancer Surgery (clinicaltrials.gov) - Sep 3, 2013
P=N/A, N=43, Terminated, Sponsor: Dan Azagury
Recruiting --> Terminated; Insufficient recruitment over time. N=95 --> 43
- Enrollment open: Cognitive-Behavioral Intervention for Worry, Uncertainty, and Insomnia for Cancer Survivors (clinicaltrials.gov) - Aug 27, 2013
P=N/A, N=75, Recruiting, Sponsor: Ohio State University Comprehensive Cancer Center
N=95 --> 43 Not yet recruiting --> Recruiting
- 5-fluorouracil / Generic mfg., oxaliplatin / Generic mfg., docetaxel / Generic mfg.
Enrollment open: Pilot Study of Perioperative Docetaxel, Oxaliplatin, and 5-Fluorouracil (FLOT) in Gastroesophageal Adenocarcinoma (clinicaltrials.gov) - Aug 26, 2013
P2, N=10, Recruiting, Sponsor: McGill University
Not yet recruiting --> Recruiting Not yet recruiting --> Recruiting
- 5-fluorouracil / Generic mfg., oxaliplatin / Generic mfg., docetaxel / Generic mfg.
New P2 trial: Pilot Study of Perioperative Docetaxel, Oxaliplatin, and 5-Fluorouracil (FLOT) in Gastroesophageal Adenocarcinoma (clinicaltrials.gov) - Aug 22, 2013
P2, N=10, Recruiting, Sponsor: McGill University
- ||||||| Takecab (vonoprazan) / Takeda, Phathom Pharma
Trial completion: Efficacy of TAK-438 Compared to AG-1749 (Lansoprazole) in the Maintenance Treatment of Healed Erosive Esophagitis (clinicaltrials.gov) - Aug 21, 2013
P3, N=607, Completed, Sponsor: Takeda
Not yet recruiting --> Recruiting Recruiting --> Completed
- Enrollment closed, Metastases: A Pilot C11-Choline PET-CT Imaging Study in Patients With Locally Advanced Esophageal Cancer (clinicaltrials.gov) - Aug 20, 2013
P1, N=22, Active, not recruiting, Sponsor: Comprehensive Cancer Center of Wake Forest University
Recruiting --> Completed Suspended --> Active, not recruiting
- ||| pantoprazole / Generic mfg.
Trial completion: Risk of Cancer Among Pantoprazole Users (clinicaltrials.gov) - Aug 20, 2013
P=N/A, N=61864, Completed, Sponsor: Pfizer
Suspended --> Active, not recruiting Enrolling by invitation --> Completed
- Surgery: FREGAT I: Outcomes After Esophageal Cancer Surgery (clinicaltrials.gov) - Aug 19, 2013
P=N/A, N=2944, Completed, Sponsor: University Hospital, Lille
- sorafenib / Generic mfg.
Biomarker, Trial termination: The Effects of Sorafenib on Molecular Barrett's Esophagus Cancer (clinicaltrials.gov) - Aug 13, 2013
P=N/A, N=3, Terminated, Sponsor: University of Chicago
Enrolling by invitation --> Completed Recruiting --> Terminated; Low accrual
- sorafenib / Generic mfg.
Biomarker, Enrollment change: The Effects of Sorafenib on Molecular Barrett's Esophagus Cancer (clinicaltrials.gov) - Aug 13, 2013
P=N/A, N=3, Terminated, Sponsor: University of Chicago
Recruiting --> Terminated; Low accrual N=15 --> 3
- Trial initiation date, Bariatric surgery: Effect of RING on Gastroesophageal Reflux (GERD) After RYGBP (clinicaltrials.gov) - Aug 12, 2013
P=N/A, N=114, Active, not recruiting, Sponsor: Clinica Gastrobese
N=15 --> 3 Initiation date: Mar 2010 --> Oct 2010
- Enrollment open: Injection of Cyanoacrylate+Lipiodol vs Cyanoacrylate+Lauromacrogol in Gastric Varices (clinicaltrials.gov) - Aug 12, 2013
P=N/A, N=96, Recruiting, Sponsor: Shanghai Zhongshan Hospital
Initiation date: Mar 2010 --> Oct 2010 Not yet recruiting --> Recruiting
- Enrollment closed, Bariatric surgery: Effect of RING on Gastroesophageal Reflux (GERD) After RYGBP (clinicaltrials.gov) - Aug 12, 2013
P=N/A, N=114, Active, not recruiting, Sponsor: Clinica Gastrobese
Not yet recruiting --> Recruiting Recruiting --> Active, not recruiting
- Enrollment change: IMRT Tomotherapy for Esophagus Cancer (clinicaltrials.gov) - Aug 8, 2013
P1, N=26, Active, not recruiting, Sponsor: Washington University School of Medicine
Recruiting --> Active, not recruiting N=40 --> 26
- Enrollment closed: IMRT Tomotherapy for Esophagus Cancer (clinicaltrials.gov) - Aug 8, 2013
P1, N=26, Active, not recruiting, Sponsor: Washington University School of Medicine
N=40 --> 26 Recruiting --> Active, not recruiting
- Enrollment open: NIR-Guided Sentinel Lymph-Node Mapping for Esophageal Cancer (clinicaltrials.gov) - Aug 6, 2013
P0, N=10, Recruiting, Sponsor: Dana-Farber Cancer Institute
Recruiting --> Active, not recruiting Active, not recruiting --> Recruiting
- | docetaxel / Generic mfg.
Trial completion: CRUK/07/013: Symptom Control With or Without Docetaxel in Treating Patients With Relapsed Esophageal Cancer or Stomach Cancer (clinicaltrials.gov) - Aug 5, 2013
P3, N=320, Completed, Sponsor: Cambridge University Hospitals NHS Foundation Trust
Active, not recruiting --> Recruiting Recruiting --> Completed
- 5-fluorouracil / Generic mfg., cisplatin / Generic mfg.
Trial completion: Endoscopic Ultrasound in Diagnosing Cancer in Patients With Localized Stomach Cancer or Esophageal Cancer (clinicaltrials.gov) - Aug 5, 2013
P=N/A, N=700, Completed, Sponsor: North Wales Organisation for Randomised Trials in Health
Recruiting --> Completed Active, not recruiting --> Completed
- Chantix (varenicline) / Pfizer
Enrollment change: Varenicline or Nicotine Patch and Nicotine Gum in Helping Smokers in a Methadone Treatment Program Stop Smoking (clinicaltrials.gov) - Aug 4, 2013
P=N/A, N=315, Completed, Sponsor: Butler Hospital
Active, not recruiting --> Completed N=602 --> 315
- Chantix (varenicline) / Pfizer
Trial completion: Varenicline or Nicotine Patch and Nicotine Gum in Helping Smokers in a Methadone Treatment Program Stop Smoking (clinicaltrials.gov) - Aug 4, 2013
P=N/A, N=315, Completed, Sponsor: Butler Hospital
N=602 --> 315 Active, not recruiting --> Completed
- Clinical: Response to Supplement and Placebo in GERD (clinicaltrials.gov) - Jul 31, 2013
P=N/A, N=24, Recruiting, Sponsor: Beth Israel Deaconess Medical Center
- Enrollment change, Metastases: E-DIS: Benefit of Chemotherapy Over Best Supportive Care in Metastatic and Squamous Cell-type Esophageal Cancer. (clinicaltrials.gov) - Jul 29, 2013
P2, N=106, Recruiting, Sponsor: Centre Oscar Lambret
Active, not recruiting --> Completed N=88 --> 106
- |||| rilotumumab (AMG 102) / Amgen
Trial completion, Metastases: AMG 102 Plus ECX for Unresectable Locally Advanced or Metastatic Gastric or Esophagogastric Junction Cancer (clinicaltrials.gov) - Jul 29, 2013
P1/2, N=130, Completed, Sponsor: Amgen
N=88 --> 106 Active, not recruiting --> Completed
- | pantoprazole / Generic mfg.
Trial completion: Intravenous (IV) Pantoprazole in Erosive Esophagitis (clinicaltrials.gov) - Jul 28, 2013
P4, N=20, Completed, Sponsor: Emory University
Active, not recruiting --> Completed Recruiting --> Completed
- Trial completion, Adverse events: CSA Depth 3: Study of CryoSpray Ablation(TM)to Determine Treatment Effect, Depth of Injury, and Side Effects in the Esophagus. (clinicaltrials.gov) - Jul 25, 2013
P4, N=10, Completed, Sponsor: CSA Medical, Inc.
Recruiting --> Completed Active, not recruiting --> Completed
- Enrollment change: Esophageal High Resolution Manometry and Dysphagia (clinicaltrials.gov) - Jul 24, 2013
P=N/A, N=247, Completed, Sponsor: Hospices Civils de Lyon
Active, not recruiting --> Completed N=368 --> 247
- oxaliplatin / Generic mfg., leucovorin calcium / Generic mfg., everolimus / Generic mfg.
Enrollment change, Metastases: Everolimus and Combination Chemotherapy in Treating Patients With Metastatic Stomach or Esophageal Cancer (clinicaltrials.gov) - Jul 23, 2013
P1/2, N=44, Active, not recruiting, Sponsor: City of Hope Medical Center
N=368 --> 247 N=26 --> 44
- ||| Revanex (revaprazan) / Yuhan
Enrollment closed, P2 data: Phase 2 Clinical Trial to Investigate the Safety, Tolerability and Efficacy of YH1885L in Patients With Non-erosive Reflux Disease(NERD) (clinicaltrials.gov) - Jul 14, 2013
P2, N=150, Active, not recruiting, Sponsor: Yuhan Corporation
N=26 --> 44 Recruiting --> Active, not recruiting
- ||| esomeprazole / Generic mfg.
Enrollment closed: Study to Investigate the Safety, Tolerability and Efficacy of YH4808 in Patients With Reflux Esophagitis (clinicaltrials.gov) - Jul 11, 2013
P2, N=150, Active, not recruiting, Sponsor: Yuhan Corporation
Recruiting --> Active, not recruiting Recruiting --> Active, not recruiting
- | fluorouracil topical / Generic mfg., cisplatin / Generic mfg.
Trial completion, HEOR, Metastases: Advanced Oesophageal Cancer Study to Compare Quality of Life and Palliation of Dysphagia. (clinicaltrials.gov) - Jul 10, 2013
P3, N=220, Completed, Sponsor: Trans-Tasman Radiation Oncology Group (TROG)
Recruiting --> Active, not recruiting Recruiting --> Completed
- ||| New P1 trial: Prospective Comparison of Large vs. Small Diameter Esophageal Stents for Palliation of Malignant Dysphagia (clinicaltrials.gov) - Jul 8, 2013
P1, N=100, Completed, Sponsor: Mayo Clinic
- || esomeprazole / Generic mfg.
Enrollment closed: Nexium Capsules RE Maintenance Specific Clinical Experience Investigation (clinicaltrials.gov) - Jul 7, 2013
P=N/A, N=647, Active, not recruiting, Sponsor: AstraZeneca
Recruiting --> Completed Recruiting --> Active, not recruiting
- | propranolol / Generic mfg.
New P4 trial: PROPRANOLOL PLUS LIGATION REDUCES RECURRENCE OF ESOPHAGEAL VARICES? (clinicaltrials.gov) - Jul 7, 2013
P4, N=100, Completed, Sponsor: Federal University of S