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128 Companies |
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121 Products |
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121 Products |
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104 Mechanisms of Action |
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7 Trials |
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1812 News |
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- Trial primary completion date: NNS-GER-SO: Effects of Non-Nutritive Sucking on Gastroesophageal Reflux and Related Apneas in Symptomatic Preterm Infants (clinicaltrials.gov) - Jan 15, 2015
P=N/A, N=30, Enrolling by invitation, Sponsor: Azienda Ospedaliera Universitaria di Bologna Policlinico S. Orsola Malpighi
Trial primary completion date: May 2015 --> Dec 2015
- Trial primary completion date: Eosinophilic Gastrointestinal Disorders Patient Registry (clinicaltrials.gov) - Jan 15, 2015
P=N/A, N=1000, Enrolling by invitation, Sponsor: Arkansas Children's Hospital Research Institute
Trial primary completion date: May 2015 --> Dec 2015 Trial primary completion date: May 2015 --> May 2016
- Trial completion, Preclinical, Enrollment change: In Vivo Assessment of Hypoxia in Gastro-intestinal Cancer Using 18F-HX4-PET: an Optimization and Reproducibility Study (clinicaltrials.gov) - Jan 15, 2015
P=N/A, N=32, Completed, Sponsor: Academisch Medisch Centrum - Universiteit van Amsterdam (AMC-UvA)
Trial primary completion date: May 2015 --> May 2016 Recruiting --> Completed | N=60 --> 32
- modafinil / Generic mfg.
Trial primary completion date: Identifying and Treating Arousal Related Deficits in Neglect and Dysphagia (clinicaltrials.gov) - Jan 15, 2015
P2, N=124, Recruiting, Sponsor: University of Arkansas
Recruiting --> Completed | N=60 --> 32 Trial primary completion date: May 2016 --> May 2017
- || Avastin (bevacizumab) / Roche
Trial primary completion date, Metastases: Pre-operative Chemotherapy Plus Bevacizumab With Early Salvage Therapy Based on PET Assessment of Response in Patients With Locally Advanced But Resectable Gastric and GEJ Adenocarcinoma (clinicaltrials.gov) - Jan 15, 2015
P2, N=60, Active, not recruiting, Sponsor: Memorial Sloan-Kettering Cancer Center
Trial primary completion date: May 2016 --> May 2017 Trial primary completion date: Aug 2014 --> Aug 2015
- |||||| Enrollment open: EndoMAXX Endoluminal Valve Technology (EVT) Compared to EndoMAXX (clinicaltrials.gov) - Jan 12, 2015
P3, N=60, Recruiting, Sponsor: Merit Medical Systems, Inc.
Trial primary completion date: Aug 2014 --> Aug 2015 Not yet recruiting --> Recruiting
- Avastin (bevacizumab) / Roche
Trial termination, Trial primary completion date, Surgery: Phase II Trial for Patients With Loco-Regional Esophageal Carcinoma (clinicaltrials.gov) - Jan 12, 2015
P2, N=6, Terminated, Sponsor: University of Michigan Cancer Center
Not yet recruiting --> Recruiting Active, not recruiting --> Terminated | Trial primary completion date: Jun 2013 --> Oct 2010; The study was unable the accrue the required number of patients within a reasonable time.
- ||| Enrollment open: The Difference of Reflux Pattern Between the Patients Who Have Postprandial Reflux Symptoms (clinicaltrials.gov) - Jan 9, 2015
P=N/A, N=51, Recruiting, Sponsor: Yonsei University
Active, not recruiting --> Terminated | Trial primary completion date: Jun 2013 --> Oct 2010; The study was unable the accrue the required number of patients within a reasonable time. Not yet recruiting --> Recruiting
- Enrollment open, Trial initiation date, Trial primary completion date, Bariatric surgery: A Prospective Blinded Randomized Study Comparing Laparoscopic Sleeve Gastrectomy and Laparoscopic Roux-en-y Gastric Bypass and Their Effect on Gastro-Esophageal Reflux Disease Using 24 Horus pH Monitoring (clinicaltrials.gov) - Jan 9, 2015
P=N/A, N=100, Recruiting, Sponsor: McMaster University
Not yet recruiting --> Recruiting Not yet recruiting --> Recruiting | Initiation date: Jun 2014 --> Oct 2014 | Trial primary completion date: Jun 2015 --> Dec 2015
- Clinical: DYnAMICS: DYsphAgia In Mechanically Ventilated ICU patientS (clinicaltrials.gov) - Jan 7, 2015
P=N/A, N=2000, Not yet recruiting, Sponsor: University Hospital Inselspital, Berne
- ||| Trial completion, Trial primary completion date: Per-Oral Endoscopic Esophagomyotomy (POEM) (clinicaltrials.gov) - Jan 6, 2015
P=N/A, N=400, Completed, Sponsor: Northwestern University
Not yet recruiting --> Recruiting | Initiation date: Jun 2014 --> Oct 2014 | Trial primary completion date: Jun 2015 --> Dec 2015 Recruiting --> Completed | Trial primary completion date: Jul 2015 --> May 2012
- Sutent (sunitinib) / Pfizer
Enrollment change, Metastases: Sunitinib, Irinotecan, Fluorouracil, and Leucovorin In Treating Patients With Advanced Stomach Cancer or Gastroesophageal Cancer (clinicaltrials.gov) - Jan 6, 2015
P1, N=23, Active, not recruiting, Sponsor: Roswell Park Cancer Institute
Recruiting --> Completed | Trial primary completion date: Jul 2015 --> May 2012 N=30 --> 23
- |||| Kepivance (palifermin) / SOBI, Amgen
Trial completion, Metastases: Study to Evaluate Palifermin in the Reduction of Dysphagia in Patients With Locally Advanced Non-Small Cell Lung Cancer (NSCLC) (clinicaltrials.gov) - Jan 5, 2015
P2, N=100, Completed, Sponsor: Swedish Orphan Biovitrum
N=30 --> 23 Active, not recruiting --> Completed
- Trial completion, Enrollment change: SWAMECO: Swallowing Difficulties With Medication Intake and Coping Strategies in Patients With Systemic Sclerosis (clinicaltrials.gov) - Dec 29, 2014
P=N/A, N=64, Completed, Sponsor: Kurt Hersberger
Active, not recruiting --> Completed Recruiting --> Completed | N=50 --> 64
- Metastases: Pain Management Smartphone Application for Patients With Stage III-IV Head and Neck Cancer Undergoing Radiation Therapy (clinicaltrials.gov) - Dec 25, 2014
P=N/A, N=30, Recruiting, Sponsor: Vanderbilt-Ingram Cancer Center
- | Trial completion, Enrollment change: Pilot Study of Efficacy of Mechanical Insufflation Exsufflation in Stroke (clinicaltrials.gov) - Dec 24, 2014
P=N/A, N=12, Completed, Sponsor: The Catholic University of Korea
Recruiting --> Completed | N=50 --> 64 Recruiting --> Completed | N=10 --> 12
- | ursodeoxycholic acid / Generic mfg.
Trial completion: Ursodiol in Treating Patients With Barrett Esophagus and Low-Grade Dysplasia (clinicaltrials.gov) - Dec 24, 2014
P2, N=36, Completed, Sponsor: National Cancer Institute (NCI)
Recruiting --> Completed | N=10 --> 12 Active, not recruiting --> Completed
- Clinical: Defining the Radiotherapy Dose and Volume Parameters Affecting Postoperative Complications in Esophageal Cancer Patients (clinicaltrials.gov) - Dec 23, 2014
P=N/A, N=150, Enrolling by invitation, Sponsor: Maastricht Radiation Oncology
- Clinical: Sleep Position May Reduce Acid Reflux Symptoms at Night (clinicaltrials.gov) - Dec 19, 2014
P=N/A, N=20, Active, not recruiting, Sponsor: Vanderbilt University
- Clinical: Mucosal Impedance in Pediatric Population (clinicaltrials.gov) - Dec 19, 2014
P=N/A, N=198, Recruiting, Sponsor: Vanderbilt University
- lapatinib / Generic mfg., carboplatin / Generic mfg., paclitaxel / Generic mfg.
Trial termination, Trial primary completion date, Combination therapy, Metastases: Lapatinib With Carboplatin and Paclitaxel in Esophagus and Gastroesophageal Junction (GEJ) (clinicaltrials.gov) - Dec 19, 2014
P1/2, N=13, Terminated, Sponsor: Case Comprehensive Cancer Center
Active, not recruiting --> Completed Active, not recruiting --> Terminated | Trial primary completion date: May 2016 --> Dec 2014; Research Cancelled
- || rabeprazole / Generic mfg.
Phase classification, Trial primary completion date, HEOR: Quality of Life in New Treatable Therapy as Rabeprazole Option for Refractory Reflux Esophagitis (clinicaltrials.gov) - Dec 19, 2014
P=N/A, N=3750, Active, not recruiting, Sponsor: Eisai Co., Ltd.
Active, not recruiting --> Terminated | Trial primary completion date: May 2016 --> Dec 2014; Research Cancelled Phase classification: P4 --> P=N/A | Trial primary completion date: Mar 2013 --> Mar 2015
- ||||| rocuronium / Generic mfg.
New P4 trial: DEPTH: Deep Neuromuscular Relaxation in Patients for Thoraco-laparoscopic Esophagectomy (clinicaltrials.gov) - Dec 19, 2014
P4, N=66, Not yet recruiting, Sponsor: Academisch Medisch Centrum - Universiteit van Amsterdam (AMC-UvA)
- |||||| Teysuno (gimeracil/oteracil/tegafur) / Nordic Group, Otsuka
Enrollment open, Metastases: S-1+Oxaliplatin vs.S-1+Cisplatin First-line Treatment of Advanced or Recurrent Non-intestinal Type Gastric Adenocarcinoma Patients (clinicaltrials.gov) - Dec 19, 2014
P3, N=446, Recruiting, Sponsor: Sun Yat-sen University
Phase classification: P4 --> P=N/A | Trial primary completion date: Mar 2013 --> Mar 2015 Not yet recruiting --> Recruiting
- Enrollment closed, Trial primary completion date, HEOR: Quality of Life and Dysphagia Following Palliative Stenting in Esophageal Cancer (clinicaltrials.gov) - Dec 19, 2014
P=N/A, N=100, Active, not recruiting, Sponsor: Centre hospitalier de l'Université de Montréal (CHUM)
Not yet recruiting --> Recruiting Recruiting --> Active, not recruiting | Trial primary completion date: Jun 2015 --> Jun 2016
- Biomarker, Trial primary completion date, FDG PET: FDG-PET-CT and Biomarkers in Esophageal Cancer (clinicaltrials.gov) - Dec 17, 2014
P=N/A, N=95, Active, not recruiting, Sponsor: M.D. Anderson Cancer Center
Recruiting --> Active, not recruiting | Trial primary completion date: Jun 2015 --> Jun 2016 Trial primary completion date: Mar 2015 --> Mar 2016
- Enrollment open, Trial initiation date, Trial primary completion date: The Effects of Cold Liquids on the Swallowing Mechanism in Preterm Infants (clinicaltrials.gov) - Dec 13, 2014
P=N/A, N=10, Recruiting, Sponsor: Winthrop University Hospital
Trial primary completion date: Mar 2015 --> Mar 2016 Not yet recruiting --> Recruiting | Initiation date: May 2013 --> Dec 2013 | Trial primary completion date: May 2014 --> Aug 2015
- Trial completion, Enrollment change, Trial primary completion date, Surgery: The Role of Anti-Reflux Surgery for Gastroesophageal Reflux Disease in Premature Infants With Bronchopulmonary Dysplasia (clinicaltrials.gov) - Dec 12, 2014
P4, N=2, Completed, Sponsor: The University of Texas Health Science Center, Houston
Not yet recruiting --> Recruiting | Initiation date: May 2013 --> Dec 2013 | Trial primary completion date: May 2014 --> Aug 2015 Recruiting --> Completed | N=80 --> 2 | Trial primary completion date: Jun 2012 --> May 2013
- |||| Dexilant (dexlansoprazole) / Takeda
Trial completion, IO biomarker: Does Intensive Acid Suppression Reduce Esophageal Inflammation and Recurrent Barrett's Esophagus Following Ablation? (clinicaltrials.gov) - Dec 12, 2014
P4, N=60, Completed, Sponsor: Mayo Clinic
Recruiting --> Completed | N=80 --> 2 | Trial primary completion date: Jun 2012 --> May 2013 Active, not recruiting --> Completed
- Clinical: Peroral Endoscopic Myotomy (POEM) for Esophageal Motility (clinicaltrials.gov) - Dec 11, 2014
P=N/A, N=10, Enrolling by invitation, Sponsor: University of Pennsylvania
- Xpovio (selinexor) / Karyopharm, Menarini, FORUS Therap
Enrollment open, Combination therapy: Selinexor in Combination With Irinotecan in Adenocarcinoma of Stomach and Distal Esophagus (clinicaltrials.gov) - Dec 9, 2014
P1, N=35, Recruiting, Sponsor: H. Lee Moffitt Cancer Center and Research Institute
Active, not recruiting --> Completed Not yet recruiting --> Recruiting
- Clinical data, Trial completion, Trial initiation date, Trial primary completion date: PET-CT Based Radiotherapy in Esophageal Cancer Patients (clinicaltrials.gov) - Dec 9, 2014
P=N/A, N=115, Completed, Sponsor: Maastricht Radiation Oncology
Not yet recruiting --> Recruiting Recruiting --> Completed | Initiation date: Nov 2004 --> Nov 2007 | Trial primary completion date: Dec 2011 --> May 2011
- metformin / Generic mfg., omeprazole / Generic mfg.
Trial primary completion date, IO biomarker: Vitamin D Supplementation on 15-Prostaglandin Dehydrogenase Expression in Barrett's Esophagus (clinicaltrials.gov) - Dec 7, 2014
P0, N=66, Recruiting, Sponsor: Case Comprehensive Cancer Center
Recruiting --> Completed | Initiation date: Nov 2004 --> Nov 2007 | Trial primary completion date: Dec 2011 --> May 2011 Trial primary completion date: Nov 2014 --> Jun 2015
- Enrollment closed, Trial primary completion date: BE-CAST: To Learn How Bone Structure and Bone Mass Change After Long-term PPI Use (clinicaltrials.gov) - Dec 6, 2014
P=N/A, N=116, Active, not recruiting, Sponsor: University of Pennsylvania
Trial primary completion date: Nov 2014 --> Jun 2015 Recruiting --> Active, not recruiting | Trial primary completion date: Jan 2013 --> Apr 2015
- Trial primary completion date: Cologne Esophageal Response Prediction Study (CERP-Study) (clinicaltrials.gov) - Dec 6, 2014
P=N/A, N=80, Recruiting, Sponsor: Elfriede Bollschweiler
Recruiting --> Active, not recruiting | Trial primary completion date: Jan 2013 --> Apr 2015 Trial primary completion date: Dec 2010 --> Dec 2014
- Biomarker: VARIANZ: Identification of Biomarkers for Prediction of Response or Resistance Against Target Therapy in Gastric Cancer (clinicaltrials.gov) - Dec 6, 2014
P=N/A, N=500, Recruiting, Sponsor: University of Leipzig
- ||||| Trial initiation date: EndoMAXX Endoluminal Valve Technology (EVT) Compared to EndoMAXX (clinicaltrials.gov) - Dec 5, 2014
P3, N=60, Not yet recruiting, Sponsor: Merit Medical Systems, Inc.
Trial primary completion date: Dec 2010 --> Dec 2014 Initiation date: Sep 2014 --> Dec 2014
- Enrollment change, Trial withdrawal, Trial primary completion date: Voice Analysis Using the LPC (Linear Predictive Coding)Method for the Prediction of Aspiration (clinicaltrials.gov) - Dec 5, 2014
P=N/A, N=0, Withdrawn, Sponsor: Ulsan University Hospital
Initiation date: Sep 2014 --> Dec 2014 N=34 --> 0 | Recruiting --> Withdrawn | Trial primary completion date: Jun 2014 --> Dec 2014
- ||| Enrollment closed, Trial primary completion date: Time Interval for Endoscopic Variceal Ligation (clinicaltrials.gov) - Dec 5, 2014
P4, N=90, Active, not recruiting, Sponsor: University of Southern California
N=34 --> 0 | Recruiting --> Withdrawn | Trial primary completion date: Jun 2014 --> Dec 2014 Recruiting --> Active, not recruiting | Trial primary completion date: Aug 2013 --> Sep 2015
- Trial completion, Enrollment change, Trial primary completion date: Bethanechol for Eosinophilic Esophagitis (clinicaltrials.gov) - Dec 5, 2014
P2, N=2, Completed, Sponsor: University of Iowa
Recruiting --> Active, not recruiting | Trial primary completion date: Aug 2013 --> Sep 2015 Recruiting --> Completed | N=40 --> 2 | Trial primary completion date: Dec 2015 --> Jul 2014
- Omegaven (omega-3 long-chain polyunsaturated fatty acids) / Fresenius Kabi
Trial suspension, Trial primary completion date: Study of Additive Omega-3 Fish Oil to Palliative Chemotherapy to Treat Oesophagogastric Cancer (clinicaltrials.gov) - Dec 5, 2014
P2, N=45, Suspended, Sponsor: University Hospitals, Leicester
Recruiting --> Completed | N=40 --> 2 | Trial primary completion date: Dec 2015 --> Jul 2014 Recruiting --> Suspended | Trial primary completion date: May 2014 --> Dec 2015
- Enrollment change: RSPT: Respiratory-Swallow Training in Veterans With Oropharyngeal Cancer (clinicaltrials.gov) - Dec 5, 2014
P2, N=30, Completed, Sponsor: Department of Veterans Affairs
Recruiting --> Suspended | Trial primary completion date: May 2014 --> Dec 2015 N=58 --> 30
- Enrollment closed: Barrett&Apos;s Intervention for Dysplasia by Endoscopy (clinicaltrials.gov) - Dec 5, 2014
P=N/A, N=100, Active, not recruiting, Sponsor: University Hospitals, Leicester
N=58 --> 30 Not yet recruiting --> Active, not recruiting
- Trial completion, Trial primary completion date, HEOR: Home Jejunostomy Feeding Following Esophagectomy/Gastrectomy (clinicaltrials.gov) - Dec 5, 2014
P=N/A, N=54, Completed, Sponsor: University Hospitals, Leicester
Not yet recruiting --> Active, not recruiting Recruiting --> Completed | Trial primary completion date: May 2014 --> Aug 2014
- | Trial completion: Study To Determine The Maximum Range of Light Doses At Two HPPH Doses With Acceptable Normal Tissue Toxicity For PDT Treatment Of High Grade Dysplasia,CIS or Early Adenocarcinoma In Barrett's Esophagus (clinicaltrials.gov) - Dec 5, 2014
P1, N=18, Completed, Sponsor: Roswell Park Cancer Institute
Recruiting --> Completed | Trial primary completion date: May 2014 --> Aug 2014 Active, not recruiting --> Completed
- docetaxel / Generic mfg.
Trial completion: Safety and Efficacy of Neoadjuvant Radiochemotherapy in Adenocarcinoma of the Gastric-oesophageal Junction (clinicaltrials.gov) - Dec 5, 2014
P1/2, N=25, Completed, Sponsor: Johannes Gutenberg University Mainz
Active, not recruiting --> Completed Recruiting --> Completed
- cisplatin / Generic mfg., paclitaxel / Generic mfg., epirubicin / Generic mfg.
Enrollment closed, Enrollment change: Preoperative Dose-dense Chemotherapy With Weekly Cisplatin, Epirubicin and Paclitaxel to Treat Patients With Locally Gastric Cancer (clinicaltrials.gov) - Nov 28, 2014
P2, N=30, Active, not recruiting, Sponsor: Centre Hospitalier Universitaire de Besancon
Recruiting --> Completed Recruiting --> Active, not recruiting | N=61 --> 30
- Trial primary completion date, HEOR: Quality of Life After Esophagectomy for Cancer - Step 2 (clinicaltrials.gov) - Nov 25, 2014
P=N/A, N=128, Recruiting, Sponsor: University of Padova
Recruiting --> Active, not recruiting | N=61 --> 30 Trial primary completion date: Dec 2014 --> Jun 2015
- Trial primary completion date, HEOR: Quality of Life After Esophagectomy for Cancer - Step 1 (clinicaltrials.gov) - Nov 25, 2014
P=N/A, N=128, Recruiting, Sponsor: University of Padova
Trial primary completion date: Dec 2014 --> Jun 2015 Trial primary completion date: Dec 2014 --> Jun 2015
- sirolimus / Generic mfg.
Trial primary completion date: Sirolimus for Eosinophil-Associated Gastrointestinal Disorders (clinicaltrials.gov) - Nov 24, 2014
P1, N=75, Recruiting, Sponsor: National Institute of Allergy and Infectious Diseases (NIAID)
Trial primary completion date: Dec 2014 --> Jun 2015 Trial primary completion date: Jun 2015 --> Sep 2016