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128 Companies |
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121 Products |
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121 Products |
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104 Mechanisms of Action |
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7 Trials |
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1812 News |
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- esomeprazole / Generic mfg.
Trial primary completion date: The Gastrointestinal Microbiome of Infants With GERD and PPI Therapy: a Pilot Study (clinicaltrials.gov) - Oct 23, 2015
P=N/A, N=20, Recruiting, Sponsor: Medical University of Graz
Trial primary completion date: May 2015 --> May 2016
- Trial termination: Impact of Weight Loss on Gastroesophageal Reflux Disease in Overweight and Obese Subjects: a Prospective Study (clinicaltrials.gov) - Oct 23, 2015
P1/2, N=100, Terminated, Sponsor: Midwest Biomedical Research Foundation
Trial primary completion date: May 2015 --> May 2016 Recruiting --> Terminated; Closed due to lack of recruitment
- | New P2 trial: HX4 SD: Tumor Hypoxia With HX4 PET in Several Diseases (clinicaltrials.gov) - Oct 23, 2015
P2, N=120, Not yet recruiting, Sponsor: Maastricht Radiation Oncology
- Trial completion: Transient Receptor Potential Vanilloid One (TRPV1) Receptor Expression in Children With Retrosternal Pain (clinicaltrials.gov) - Oct 23, 2015
P=N/A, N=77, Completed, Sponsor: Medical College of Wisconsin
Recruiting --> Terminated; Closed due to lack of recruitment Active, not recruiting --> Completed
- 5-fluorouracil / Generic mfg., cisplatin / Generic mfg., epirubicin / Generic mfg.
Trial primary completion date, HEOR, Surgery: QUINTETT: Quality of Life in Neoadjuvant Versus Adjuvant Therapy of Esophageal Cancer Treatment Trial (clinicaltrials.gov) - Oct 22, 2015
P3, N=96, Recruiting, Sponsor: Richard Malthaner
Active, not recruiting --> Completed Trial primary completion date: Apr 2012 --> Apr 2017
- | Trial termination: Endoscopic Resection or Ablation for Patients With Dysplasia or Cancer Requiring Treatment of Barrett's Esophagus (clinicaltrials.gov) - Oct 22, 2015
P3, N=82, Terminated, Sponsor: Midwest Biomedical Research Foundation
Trial primary completion date: Apr 2012 --> Apr 2017 Recruiting --> Terminated; Recruitment goals not being met
- Trial termination, HEOR: Quality of Life in Barrett's Esophagus and Gastro-Esophageal Reflux Disease (clinicaltrials.gov) - Oct 22, 2015
P=N/A, N=384, Terminated, Sponsor: Midwest Biomedical Research Foundation
Recruiting --> Terminated; Recruitment goals not being met Recruiting --> Terminated; Lack of recruitment
- | Trial suspension: BEST: The Study of Barrett's Esophagus: What Are the Factors of Progression (clinicaltrials.gov) - Oct 22, 2015
P=N/A, N=2500, Suspended, Sponsor: Midwest Biomedical Research Foundation
Recruiting --> Terminated; Lack of recruitment Recruiting --> Suspended
- New P1/2 trial: The Effects of Whole Food Intervention on Mucositis in Patients Treated for Thoracic Cancer (clinicaltrials.gov) - Oct 22, 2015
P1/2, N=7, Terminated, Sponsor: Providence Health & Services
- Enrollment closed: Prospective Study to Compare the Efficacy of E.G.Scan to Detect Barrett's Esophagus Compared With Standard Endoscopy (clinicaltrials.gov) - Oct 22, 2015
P=N/A, N=100, Active, not recruiting, Sponsor: Mayo Clinic
Recruiting --> Suspended Recruiting --> Active, not recruiting
- Enrollment closed: Stroke Swallowing Screening Tool Validation (clinicaltrials.gov) - Oct 22, 2015
P=N/A, N=305, Active, not recruiting, Sponsor: VA Office of Research and Development
Recruiting --> Active, not recruiting Recruiting --> Active, not recruiting
- | Trial completion: Early Oral Feeding Following Thoracolaparoscopic Oesophagectomy in Patients With Esophageal Cancer (clinicaltrials.gov) - Oct 16, 2015
P3, N=280, Completed, Sponsor: Yin Li
Recruiting --> Active, not recruiting Recruiting --> Completed
- Trial completion, Trial primary completion date: NNS-GER-SO: Effects of Non-Nutritive Sucking on Gastroesophageal Reflux and Related Apneas in Symptomatic Preterm Infants (clinicaltrials.gov) - Oct 16, 2015
P=N/A, N=30, Completed, Sponsor: Azienda Ospedaliera Universitaria di Bologna Policlinico S. Orsola Malpighi
Recruiting --> Completed Enrolling by invitation --> Completed | Trial primary completion date: Dec 2015 --> Aug 2015
- Trial completion, Enrollment change, Trial initiation date, Trial primary completion date: Transcranial Direct Current Stimulation for Dysphagia Therapy in Acute Stroke Patients (clinicaltrials.gov) - Oct 14, 2015
P=N/A, N=60, Completed, Sponsor: University Hospital Muenster
Enrolling by invitation --> Completed | Trial primary completion date: Dec 2015 --> Aug 2015 Recruiting --> Completed | N=100 --> 60 | Initiation date: Jan 2012 --> Jun 2012 | Trial primary completion date: Dec 2015 --> Dec 2014
- | ONO-8539 / Ono Pharma
Trial completion, Enrollment change: A Study of the Effect of ONO-8539 on Oesophageal Pain Hypersensitivity in Patients With Non-erosive Reflux Disease (clinicaltrials.gov) - Oct 14, 2015
P1, N=14, Completed, Sponsor: Ono Pharmaceutical Co. Ltd
Recruiting --> Completed | N=100 --> 60 | Initiation date: Jan 2012 --> Jun 2012 | Trial primary completion date: Dec 2015 --> Dec 2014 Active, not recruiting --> Completed | N=30 --> 14
- | Trial completion, Enrollment change, Trial primary completion date: Study of Tongue Strengthening for Swallowing Problems (clinicaltrials.gov) - Oct 14, 2015
P=N/A, N=34, Completed, Sponsor: University of Wisconsin, Madison
Active, not recruiting --> Completed | N=30 --> 14 Not yet recruiting --> Completed | N=100 --> 34 | Trial primary completion date: Mar 2014 --> Sep 2015
- Trial completion: BE-CAST: To Learn How Bone Structure and Bone Mass Change After Long-term PPI Use (clinicaltrials.gov) - Oct 14, 2015
P=N/A, N=106, Completed, Sponsor: University of Pennsylvania
Not yet recruiting --> Completed | N=100 --> 34 | Trial primary completion date: Mar 2014 --> Sep 2015 Active, not recruiting --> Completed
- Trial primary completion date: 4-Dimensional CT Derived Ventilation Versus SPECT Aerosol Ventilation in Patients With Thoracic Malignancies (clinicaltrials.gov) - Oct 3, 2015
P2, N=36, Active, not recruiting, Sponsor: M.D. Anderson Cancer Center
Active, not recruiting --> Completed Trial primary completion date: Nov 2016 --> Nov 2017
- Trial completion, Enrollment change: Risk Factors for Barrett's Esophagus in Patients With BE, Gastroesophageal Reflux, or Gastrointestinal Bleeding (clinicaltrials.gov) - Oct 3, 2015
P=N/A, N=170, Completed, Sponsor: Massachusetts General Hospital
Trial primary completion date: Nov 2016 --> Nov 2017 Active, not recruiting --> Completed | N=350 --> 170
- Trial completion: Zinc Supplements in Lowering Cadmium Levels in Smokers (clinicaltrials.gov) - Oct 3, 2015
P2, N=61, Completed, Sponsor: Comprehensive Cancer Center of Wake Forest University
Active, not recruiting --> Completed | N=350 --> 170 Active, not recruiting --> Completed
- Trial primary completion date: CoFAR5: Eosinophilic Esophagitis Databank (clinicaltrials.gov) - Oct 2, 2015
P=N/A, N=715, Recruiting, Sponsor: National Institute of Allergy and Infectious Diseases (NIAID)
Active, not recruiting --> Completed Trial primary completion date: Jun 2015 --> Dec 2015
- Erbitux (cetuximab) / Eli Lilly, EMD Serono
Trial completion, Metastases: Erlotinib Hydrochloride and Cetuximab in Treating Patients With Advanced Gastrointestinal Cancer, Head and Neck Cancer, Non-Small Cell Lung Cancer, or Colorectal Cancer (clinicaltrials.gov) - Sep 30, 2015
P1, N=43, Completed, Sponsor: National Cancer Institute (NCI)
Trial primary completion date: Jun 2015 --> Dec 2015 Active, not recruiting --> Completed
- | montelukast / Generic mfg.
Trial completion, Enrollment change: Trial of Montelukast in Eosinophilic Esophagitis (clinicaltrials.gov) - Sep 25, 2015
P1, N=41, Completed, Sponsor: Mayo Clinic
Active, not recruiting --> Completed Recruiting --> Completed | N=60 --> 41
- Trial primary completion date, Bariatric surgery: A Prospective Blinded Randomized Study Comparing Laparoscopic Sleeve Gastrectomy and Laparoscopic Roux-en-y Gastric Bypass and Their Effect on Gastro-Esophageal Reflux Disease Using 24 Horus pH Monitoring (clinicaltrials.gov) - Sep 25, 2015
P=N/A, N=100, Recruiting, Sponsor: McMaster University
Recruiting --> Completed | N=60 --> 41 Trial primary completion date: Dec 2015 --> Dec 2016
- | Trial completion, Trial primary completion date: The Study to Evaluate Efficacy and Safety of Newrabell® Tab.(Rabeprazole Sodium) 10mg b.i.d in Refractory GERD (clinicaltrials.gov) - Sep 25, 2015
P4, N=39, Completed, Sponsor: Chong Kun Dang Pharmaceutical
Trial primary completion date: Dec 2015 --> Dec 2016 Recruiting --> Completed | Trial primary completion date: Oct 2014 --> May 2015
- Trial completion, Trial primary completion date: A Clinical Study of Per Oral Endoscopic Myotomy (POEM) in Patients Suffering From Achalasia (clinicaltrials.gov) - Sep 25, 2015
P=N/A, N=10, Completed, Sponsor: McMaster University
Recruiting --> Completed | Trial primary completion date: Oct 2014 --> May 2015 Not yet recruiting --> Completed | Trial primary completion date: Jan 2014 --> Dec 2014
- || AMG 337 / ImmunityBio, Amgen
Trial primary completion date: Phase 2 Study of AMG 337 in MET Amplified Gastric/Esophageal Adenocarcinoma or Other Solid Tumors (clinicaltrials.gov) - Sep 24, 2015
P2, N=60, Active, not recruiting, Sponsor: Amgen
Not yet recruiting --> Completed | Trial primary completion date: Jan 2014 --> Dec 2014 Trial primary completion date: Sep 2015 --> Apr 2016
- Biomarker, Trial completion: Stratifying Risk in Barrett's Esophagus: A Pilot Study for Biomarker-based Patient Management (clinicaltrials.gov) - Sep 24, 2015
P=N/A, N=111, Completed, Sponsor: University of North Carolina, Chapel Hill
Trial primary completion date: Sep 2015 --> Apr 2016 Enrolling by invitation --> Completed
- New trial: Should I Continue Taking My Acid Reflux Medication? Development and Pilot Testing of a Patient Decision Aid (clinicaltrials.gov) - Sep 23, 2015
P=N/A, N=54, Not yet recruiting, Sponsor: University of Ottawa
- Futaden (lafutidine) / Emcure
New trial: Proton Pump Inhibitors and Risk of Community-acquired Pneumonia (clinicaltrials.gov) - Sep 22, 2015
P=N/A, N=4238504, Completed, Sponsor: Canadian Network for Observational Drug Effect Studies, CNODES
- |||||||||| K-CAB Tab (tegoprazan) / RaQualia, Sebela
New P3 trial: Study to Evaluate the Safety and Efficacy of CJ-12420 in Patients With Non Erosive Reflux Disease (clinicaltrials.gov) - Sep 22, 2015
P3, N=324, Not yet recruiting, Sponsor: CJ HealthCare Corporation
- | Enrollment status, Enrollment change: Gastroesophageal Reflux Treatment in Scleroderma (clinicaltrials.gov) - Sep 21, 2015
P3, N=80, Recruiting, Sponsor: Khon Kaen University
Enrolling by invitation --> Completed Enrolling by invitation --> Recruiting | N=250 --> 80
- ||| cendakimab (CC-93538) / AbbVie, BMS
Enrollment closed: HEROES: Dose Ranging Study of RPC4046 in Eosinophilic Esophagitis (clinicaltrials.gov) - Sep 17, 2015
P2, N=90, Active, not recruiting, Sponsor: Receptos, Inc.
Enrolling by invitation --> Recruiting | N=250 --> 80 Recruiting --> Active, not recruiting
- New trial: Prevalence of Human Papillomavirus in Barrett Esophagus Compared With Controls (clinicaltrials.gov) - Sep 14, 2015
P=N/A, N=219, Completed, Sponsor: University Hospital, Angers
- New trial: Early Integration of Palliative Care in Esophageal Cancer Patients (clinicaltrials.gov) - Sep 14, 2015
P=N/A, N=120, Not yet recruiting, Sponsor: McMaster University
- New trial: a4b7 Integrin in Eosinophilic Esophagitis (clinicaltrials.gov) - Sep 10, 2015
P=N/A, N=16, Not yet recruiting, Sponsor: Massachusetts General Hospital
- Enrollment closed: Gene Methylation in the Diagnosis of Barrett's Esophagus: Identification of Candidate Diagnostic Markers (clinicaltrials.gov) - Sep 8, 2015
P=N/A, N=253, Active, not recruiting, Sponsor: Mayo Clinic
Recruiting --> Active, not recruiting Enrolling by invitation --> Active, not recruiting
- ||| Enrollment closed, Trial primary completion date: Transoral Incisionless Fundoplication (TIF) Versus Sham for Treatment of Gastroesophageal Reflux Disease (GERD) (clinicaltrials.gov) - Sep 3, 2015
P4, N=60, Active, not recruiting, Sponsor: EndoGastric Solutions
Enrolling by invitation --> Active, not recruiting Recruiting --> Active, not recruiting | Trial primary completion date: May 2015 --> Sep 2015
- Trial completion: StentMig: Treatment of Malignant Strictures in Esophagus and Gastroesophageal Junction With Covered or Partially Covered Stent. (clinicaltrials.gov) - Sep 2, 2015
P2, N=80, Completed, Sponsor: Karolinska University Hospital
Recruiting --> Active, not recruiting | Trial primary completion date: May 2015 --> Sep 2015 Recruiting --> Completed
- ceftriaxone / Generic mfg.
Trial completion, Enrollment change, Trial primary completion date: Comparison of 3 Days and 7 Days Intravenous Ceftriaxone Prophylaxis for Variceal Bleeding (clinicaltrials.gov) - Sep 1, 2015
P4, N=79, Completed, Sponsor: Far Eastern Memorial Hospital
Recruiting --> Completed Recruiting --> Completed | N=100 --> 79 | Trial primary completion date: Jun 2011 --> Mar 2013
- Enrollment open, Trial initiation date, Trial primary completion date: Swallowing and Breathing Exercises for Dysphagia in Parkinson Disease (clinicaltrials.gov) - Aug 29, 2015
P=N/A, N=100, Recruiting, Sponsor: Federal University of Bahia
Recruiting --> Completed | N=100 --> 79 | Trial primary completion date: Jun 2011 --> Mar 2013 Not yet recruiting --> Recruiting | Initiation date: Apr 2014 --> Nov 2013 | Trial primary completion date: Sep 2014 --> Apr 2016
- bupropion / Generic mfg.
Trial completion: Bupropion in Helping Adults Stop Smoking (clinicaltrials.gov) - Aug 28, 2015
P2, N=97, Completed, Sponsor: Roswell Park Cancer Institute
Not yet recruiting --> Recruiting | Initiation date: Apr 2014 --> Nov 2013 | Trial primary completion date: Sep 2014 --> Apr 2016 Active, not recruiting --> Completed
- Trial primary completion date: Esophageal Absorption in EoE (clinicaltrials.gov) - Aug 22, 2015
P=N/A, N=40, Recruiting, Sponsor: Mayo Clinic
Active, not recruiting --> Completed Trial primary completion date: Sep 2015 --> Dec 2015
- |||| Trial primary completion date: EndoMAXX Endoluminal Valve Technology (EVT) Compared to EndoMAXX (clinicaltrials.gov) - Aug 22, 2015
P3, N=60, Recruiting, Sponsor: Merit Medical Systems, Inc.
Trial primary completion date: Sep 2015 --> Dec 2015 Trial primary completion date: Aug 2015 --> Jan 2016
- | lansoprazole / Generic mfg., omeprazole / Generic mfg., esomeprazole / Generic mfg.
New P4 trial, Reflex: Comparison of Voice Therapy and Antireflex Therapy in LPR (clinicaltrials.gov) - Aug 21, 2015
P4, N=180, Not yet recruiting, Sponsor: Temple University
- || esomeprazole / Generic mfg.
Enrollment change, Trial primary completion date: Efficacy of Proton Pump Inhibitor for Chronic Cough Caused by Gastroesophageal Reflux; Double-blind, Placebo-controlled, Randomized Clinical Trial (clinicaltrials.gov) - Aug 21, 2015
P=N/A, N=60, Recruiting, Sponsor: Yonsei University
Trial primary completion date: Aug 2015 --> Jan 2016 N=132 --> 60 | Trial primary completion date: Apr 2014 --> Feb 2016
- Clinical data, New trial: Evaluating the Impact of Automated Evaluation of Gastrointestinal Symptoms (AEGIS) on Clinical Outcomes (clinicaltrials.gov) - Aug 20, 2015
P=N/A, N=448, Not yet recruiting, Sponsor: Cedars-Sinai Medical Center
- omeprazole / Generic mfg.
Enrollment closed, Trial primary completion date: CYP2C19 Genotype Predictor of Gastric Acid Suppression (clinicaltrials.gov) - Aug 19, 2015
P0, N=100, Active, not recruiting, Sponsor: Mayo Clinic
N=132 --> 60 | Trial primary completion date: Apr 2014 --> Feb 2016 Recruiting --> Active, not recruiting | Trial primary completion date: Jul 2015 --> Dec 2016
- TheraCIM (nimotuzumab) / Daiichi Sankyo, Oncoscience, Biocon
Trial completion, Combination therapy, Metastases: Nimotuzumab in Combination With Chemoradiation for Esophageal Cancer (clinicaltrials.gov) - Aug 19, 2015
P1, N=11, Completed, Sponsor: Biotech Pharmaceutical Co., Ltd.
Recruiting --> Active, not recruiting | Trial primary completion date: Jul 2015 --> Dec 2016 Recruiting --> Completed
- New P2 trial: FIDUCOR: Placing Trust in Endoscopic Ultrasonography: Impact on Planning Conformal Radiotherapy of Cancer of the Esophagus and Rectum (clinicaltrials.gov) - Aug 18, 2015
P2, N=29, Recruiting, Sponsor: Institut Paoli-Calmettes