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- | Journal: Occurrences and antibiotic susceptibility patterns of Listeria monocytogenes in raw meat samples from abattoir and butcher shops in Jimma Town, Southwest Ethiopia. (Pubmed Central) - Mar 10, 2025
Tetracycline, penicillin, nalidixic acid, and cloxacillin, however, are resistant to them...Therefore, training is needed on hygienic meat handling practices for meat handlers to minimize the risk of foodborne diseases. Lowering the level of antibiotic resistance also requires controlling the optimal use of antibiotics in animals bred for food.
- | nalidixic acid / Generic mfg.
Journal: Investigation of Intestinal Health in Broiler Chickens Following Salmonella Typhimurium and Coccidiosis Vaccination and Challenge with Salmonella Typhimurium. (Pubmed Central) - Mar 10, 2025
On day 28, all groups were challenged with a ST marker strain resistant to nalidixic acid...Gene expression of claudin 1, claudin 4, E-cadherin, ?-catenin, and zonula occludens 2 in the cecal wall differed between the groups on days 28 and 42. These findings indicated the significant influence of ST and coccidiosis vaccines on the intestinal health of broilers; however, further studies are required to clarify the implications for health and performance.
- | ampicillin / Generic mfg., nalidixic acid / Generic mfg., trimethoprim/sulfamethoxazole / Generic mfg.
Journal: Unveiling the Hidden Mechanism: How LuxS/AI-2 quorum sensing system drives antimicrobial resistance in Salmonella pullorum through activation of the efflux pump AcrAB-TolC. (Pubmed Central) - Mar 9, 2025
In summary, AMR in SP isolates was enhanced by AI-2 through the promotion of the the expression of the soxS gene and the SoxS protein, activating the efflux pump. Exploring the AMR mechanism of the SP strain provides important baseline information for controlling outbreaks of yellow chicken salmonellosis.
- | nalidixic acid / Generic mfg.
Journal: An MDR Salmonella Enteritidis sublineage associated with gastroenteritis outbreaks and invasive disease in China. (Pubmed Central) - Mar 6, 2025
These clades have induced extensive outbreaks of gastroenteritis and serious cases of iNTS in China, underscoring the pressing nature and severity of this public health crisis. Implementing the One-Health strategy, longstanding routine surveillance and further genomic epidemiological studies are urgently required to capture epidemics, monitor changes in bacterial populations and determine the consequent risk to global public health.
- || nalidixic acid / Generic mfg., tetracycline / Generic mfg.
Retrospective data, Review, Journal: Pooled prevalence of Escherichia coli phenotypic and genotypic antimicrobial resistance profiles in poultry: systematic review and meta-analysis. (Pubmed Central) - Mar 6, 2025
Tetracycline resistance genes had the highest prevalence, with 29.78% of isolates (498/1076) positive for at least one of the three genes (tetA, tetB and/or tetC). The levels of phenotypic and genotypic prevalence of E. coli in poultry can provide a scientific basis for the control of antibiotic-resistant strains and contribute to the competent authorities to guide the management interventions that best suit the different geographical regions.
- | Journal: Fecal carriage and molecular characterization of carbapenem-resistant Enterobacteriaceae from hospitalized children in a tertiary hospital of Shandong, China. (Pubmed Central) - Mar 5, 2025
CRE isolates showed low resistance to amikacin (20%), and none of the isolates were resistant to tigecycline...MLST analysis revealed diverse sequence types (STs) among CRE isolates, with ST167 being a common ST among E. coli isolates. This study revealed bla NDM E. coli were the dominant isolates in fecal samples of hospitalized children in Shandong Province, with a broad multidrug resistance to antibiotics, emphasizing that infection control measures need to be taken to limit the spread of these strains.
- | Journal: Drug resistance and genotyping studies of Salmonella Enteritidis isolated from broiler chickens in Iran. (Pubmed Central) - Mar 5, 2025
However, all isolates were sensitive to meropenem, ceftazidime and aztreonam...These data highlight the great potential risks of the presence and transmission of highly pathogenic MDR Salmonella to humans from chicken meat sources, as well as the need for more effective surveillance for antimicrobial use in the poultry industry. Reducing/optimizing the use of antimicrobials, improving poultry management procedures, using probiotics and biosecurity or vaccines are essential to deal with this issue.
- | Journal: Investigation of antimicrobial susceptibility and resistance gene prevalence in Capnocytophaga spp. isolated from dogs and cats and characterization of novel class A ?-lactamase CST-1. (Pubmed Central) - Mar 4, 2025
in animal oral cavities. The findings have clinical implications, especially in antimicrobial treatment.
- || ciprofloxacin oral / Generic mfg., nalidixic acid / Generic mfg., tetracycline / Generic mfg.
Retrospective data, Review, Journal: Prevalence, antibiotic resistance, resistance and virulence determinants of Campylobacter jejuni in China: A systematic review and meta-analysis. (Pubmed Central) - Mar 3, 2025
In summary, C. jejuni has a high prevalence with regional characteristics, and antibiotic resistance of this bacterium especially animal sources remains a serious problem in China. Comprehensive monitoring and control measures for this pathogen are urgently needed to ensure food safety and public health.
- | Journal: Epidemiology of antimicrobial resistant diarrheagenic Escherichia coli pathotypes from children, livestock and food in Dagoretti South, Nairobi Kenya. (Pubmed Central) - Feb 27, 2025
Logistic regression analysis revealed that on-site disposal of animal manure and garbage, along with a recent history of diarrhea, were significantly associated with AMR carriage in children (p < 0.05). These findings emphasize the need for One Health interventions to curb emergence and spread of AMR in these close contact populations.
- | ampicillin / Generic mfg., nalidixic acid / Generic mfg., tetracycline / Generic mfg.
Journal: Recent Occurrence and Rapid Spread of Multidrug-Resistant Salmonella Infantis in Broiler Flocks in Korea. (Pubmed Central) - Feb 27, 2025
To mitigate the risks associated with the rapid spread of MDR Salmonella Infantis in poultry production and its potential impact on human health, this study provides valuable insights into implementing effective control measures to reduce Salmonella in broiler production in Korea. Further highlighting the critical importance of enhanced biosecurity and continuous surveillance.
- | Journal: Antibiotic resistance and virulence profile of Klebsiella pneumoniae isolated from wild Sumatran Orangutans (Pongo abelii). (Pubmed Central) - Feb 27, 2025
Furthermore, antibiotic resistance genes were detected in the isolates with the following prevalence: bla TEM gene (six isolates; 100%), bla SHV (six isolates; 100%), bla CTX-M gene (four isolates; 66.67%), and tetA gene (four isolates; 66.67%). This study revealed the virulence and resistance profile of K. pneumoniae bacterium isolated from wild Sumatran orangutans, which is essential for formulating effective conservation and healthcare strategies.
- | ampicillin / Generic mfg., nalidixic acid / Generic mfg., rifampicin / Generic mfg.
Journal: What Is the Impact of Antibiotic Resistance Determinants on the Bacterial Death Rate? (Pubmed Central) - Feb 26, 2025
Moreover, epistasis may occur when different resistance determinants occur in the same cell, impacting the bactericidal potential of the antibiotic of choice. These results have significant implications for optimizing bacterial eradication protocols in clinical settings, as well as in animal health and industrial food safety management.
- | Journal: Antibiotic-Resistant Salmonella Circulation in the Human Population in Campania Region (2010-2023). (Pubmed Central) - Feb 26, 2025
Serovar-specific resistance varied: S. monophasic Typhimurium was resistant to azithromycin (100.0%), tetracycline (93.0%), and ampicillin (92.4%); S. Enteritidis showed 100.0% resistance to azithromycin; S. Typhimurium had high resistance to azithromycin, streptomycin, and ampicillin; and S. Infantis was resistant to erythromycin, sulfonamides, and azithromycin. The study highlights a troubling prevalence of Salmonella-resistant strains, emphasizing the need for infection prevention, proper antibiotic use in humans and animals, and the development of new antibiotics.
- | Journal: Plasmid-borne mcr-1 and replicative transposition of episomal and chromosomal blaNDM-1, blaOXA-69, and blaOXA-23 carbapenemases in a clinical Acinetobacter baumannii isolate. (Pubmed Central) - Feb 24, 2025
There was phenotypic resistance to 22 of the 25 antibiotics tested, intermediate resistance to levofloxacin and nalidixic acid, and susceptibility to tigecycline, which corresponded to the 27 resistance genes found in the genome, most of which occurred in multiple copies through replicative transposition...The varied mechanisms available to this strain to overcome antibiotic resistance and spread to other areas and/or transfer its resistance determinants are worrying. This is ultimately a risk to public health, evincing the need for antibiotic stewardship.
- | Journal: Monitoring antimicrobial resistance in Salmonella enterica serovar Infantis isolates of poultry, livestock, and humans across the United States, 2013-2020. (Pubmed Central) - Feb 23, 2025
High resistance to tetracycline, nalidixic acid, and sulfisoxazole and low resistance to cefoxitin and amoxicillin-clavulanic acid were detected among livestock, poultry, and human isolates. Reduced susceptibility to ciprofloxacin was observed in 52.46
- | ampicillin / Generic mfg., nalidixic acid / Generic mfg., tetracycline / Generic mfg.
Journal: Houseflies (Musca domestica) as vectors of multidrug-resistant, ESBL-producing Escherichia coli in broiler poultry farms of North India: implications for antibiotic resistance transmission. (Pubmed Central) - Feb 18, 2025
Farm-derived flies harboured a significantly higher number of MDR E. coli (unpaired t-test, p?<?0.05) than the ones isolated from flies housing a distant non-farm environment. Conclusively, this study illustrates the role of houseflies as vectors for AR transmission from AR hotspots to human communities.
- | Journal: Molecular identification of plasmid-mediated quinolone resistance genes among klebsiella pneumoniae clinical isolates from southwest Iran. (Pubmed Central) - Feb 15, 2025
This study was the first to report a high-frequency rate of PMQR genes in K. pneumoniae isolates from the clinical setting of Ahvaz, southwest Iran. As a result, antibiotic prescribing policies should be amended to hinder the further spread of PMQR genes in the studied region.
- | nalidixic acid / Generic mfg.
Journal: Impact of fresh-cut onion types and flavonoid profiles on the survival kinetics of foodborne pathogen during refrigerated storage. (Pubmed Central) - Feb 13, 2025
Fresh-cut white, yellow, red, and sweet onions were inoculated with separate four-strain cocktail(s) of nalidixic acid-adapted Salmonella spp., Escherichia coli O157:H7, and Listeria monocytogenes achieving a 4 to 5 log CFU g-1...Notably, despite having similar flavonoid levels, sweet onions showed greatest reduction of tested pathogens than red onions, suggesting that factors beyond flavonoid content may contribute to pathogen reduction. These findings provide new insights into the behavior of foodborne pathogens in fresh-cut onions and highlight the potential for flavonoids to influence pathogen survival during refrigerated storage.
- | Journal: Occurrence and cross contamination of Escherichia albertii in retail chicken outlets in Bangladesh. (Pubmed Central) - Feb 13, 2025
These findings provide new insights into the behavior of foodborne pathogens in fresh-cut onions and highlight the potential for flavonoids to influence pathogen survival during refrigerated storage. Almost all the E. albertii isolates (94.4
- | Journal: Characterization of Aeromonas Strains Isolated from Adult Patients with Diarrhea and Aquatic Environments - Beijing Municipality, China, 2016-2022. (Pubmed Central) - Feb 11, 2025
This study provides valuable insights into the prevalence and characteristics of Aeromonas. The intertwined distribution of patient- and water-derived isolates in the phylogenetic tree deserves attention.
- | ampicillin / Generic mfg., nalidixic acid / Generic mfg., tetracycline / Generic mfg.
Journal: Phenotypic and WGS-derived antibiotic resistance patterns of Salmonella Enteritidis isolates from retail meat and environment during 2014 to 2019 in China. (Pubmed Central) - Feb 11, 2025
The intertwined distribution of patient- and water-derived isolates in the phylogenetic tree deserves attention. Most MDR strains (81.43%) had NAL-AMP-FIS-STR?
- | Journal: Prevalence and characteristics of ST131-O16 and ST131-O25b clones among extended-spectrum ?-lactamase-producing Escherichia coli isolates causing bloodstream infection in Iran. (Pubmed Central) - Feb 5, 2025
Our results reinforce the surveillance of E. coli ST131 clone dissemination as a major drug-resistant pathogen and an important new public health threat in Iran. Accumulation of multiple virulence factors, ESBL carriage, and identified antimicrobial resistance patterns of ST131-O25b and ST131-O16 clones indicate a necessity to develop strategies to control the spread of these isolates in both community and hospital settings.
- | Journal: Biofilm Formation and Plasmid-Mediated Quinolone Resistance Genes at Varying Quinolone Inhibitory Concentrations in Quinolone-Resistant Bacteria Superinfecting COVID-19 Inpatients. (Pubmed Central) - Feb 5, 2025
Biofilms formed by F-GNB and NF-GNB were significantly associated with the aac(6')-Ib-cr and qnrS genes, respectively. Nearly one-third of the superinfecting bacteria in COVID-19 patients formed biofilms and had at least one PMQR gene, thus increasing the need for quinolones at higher inhibitory concentrations.
- | nalidixic acid / Generic mfg.
Journal: Examining the impact of probiotic Lactiplantibacillus pentosus 6MMI on inhibiting biofilm formation, adhesion, and virulence gene expression in Listeria monocytogenes ATCC 19115. (Pubmed Central) - Feb 5, 2025
Nearly one-third of the superinfecting bacteria in COVID-19 patients formed biofilms and had at least one PMQR gene, thus increasing the need for quinolones at higher inhibitory concentrations. The strain exhibited the highest resistance to nalidixic acid, with an inhibition zone measuring 15.20
- | Journal: Prevalence, antimicrobial resistance and phylogenetic analysis of Salmonella contamination and transmission in yellow-feathered broiler hatcheries in China. (Pubmed Central) - Feb 5, 2025
Resistance rates were highest for nalidixic acid (100.00 %), sulfamethoxazole (100.00 %), ciprofloxacin (95.69 %), and ampicillin (94.83 %)...This suggests that Salmonella in the environment may originate from chicks/eggs and spread to other stages. More attention should be paid to Salmonella contamination in yellow-feathered broiler hatcheries, and stringent measures should be taken to control the horizontal spread of Salmonella, in addition to blocking the pathway of vertical transmission.
- || ciprofloxacin oral / Generic mfg., nalidixic acid / Generic mfg.
Retrospective data, Review, Journal: Prevalence and antimicrobial resistance of Campylobacter jejuni and Campylobacter coli over time in Thailand under a One Health approach: A systematic review and meta-analysis. (Pubmed Central) - Feb 3, 2025
More attention should be paid to Salmonella contamination in yellow-feathered broiler hatcheries, and stringent measures should be taken to control the horizontal spread of Salmonella, in addition to blocking the pathway of vertical transmission. Notably, ciprofloxacin-resistant and nalidixic acid-resistant C. jejuni strains collected from chickens increased by 11.9
- | Journal: Antimicrobial Resistance Profiles of Campylobacter spp. Recovered from Chicken Farms in Two Districts of Bangladesh. (Pubmed Central) - Feb 3, 2025
AMR was more prevalent in chicken farms that used multiple antibiotics, engaged in prophylactic treatment of the birds, and improperly disposed of antibiotic packages. The high prevalence of MDR in chicken-derived Campylobacter isolates from the different regions of our study reinforces the need for more prudent use of antimicrobial compounds in Bangladeshi chicken farms.
- | Journal: Comparative Molecular Virulence Typing and Antibiotic Resistance of Campylobacter Species at the Human-Animal-Environment Interface. (Pubmed Central) - Feb 3, 2025
To effectively manage Campylobacter infections, a multifaceted strategy incorporating preventative interventions at different levels is required. This strategy should take into account practicability, effectiveness, and sustainability while strengthening surveillance systems and addressing the economics of disease prevention.
- | Journal: Prevalence and antimicrobial resistant Campylobacter spp. in broiler chicken carcasses and hygiene practises in informal urban markets in a low-income setting. (Pubmed Central) - Jan 30, 2025
More than half of the vendors had heard about food-borne illnesses, but none knew about Campylobacter spp., and the knowledge regarding hygienic practices was low. These data calls for urgent interventions to improve food safety, protect the public from foodborne illness, and prevent the spreading of AMR.
- | Journal: Prevalence and antimicrobial resistance of extended spectrum beta-lactamase (ESBL) producing Klebsiella spp. in poultry meat. (Pubmed Central) - Jan 27, 2025
These results highlighted significant carriage of multidrug-resistant (MDR) Klebsiella spp. in retail poultry meat, which insinuates that there is a need for a strategic plan in place to curb the dissemination of these multi drug resistant pathogens along the food chain.
- | Journal: Antimicrobial Resistance and Public Health Risks Associated with Staphylococci Isolated from Raw and Processed Meat Products. (Pubmed Central) - Jan 15, 2025
One hundred percent of the isolates were susceptible to ciprofloxacin, tetracycline, gemifloxacin, and cefotaxime/clavulanic acid...Current findings show widespread occurrence of MDR Staphylococcus strains in raw meat and street meat products, which is a potential risk to public health. Therefore, the study suggests strict monitoring of hygiene through the whole food chain and judicious use of antibiotics.
- | Journal: Antimicrobial resistance pattern of Escherichia coli isolated from imported frozen shrimp in Saudi Arabia. (Pubmed Central) - Dec 24, 2024
90.5%), piperacillin (156/180, 86.6%), ceftriaxone (123/180, 68.3%), nalidixic acid (95/180, 52.7%), trimethoprim sulphamethoxazole (90/180, 50%), and tetracycline (88/180, 48.8%)...A relatively high intermediate resistance of 60% (108/180) was exhibited for aztreonam...Furthermore, and interestingly, the segregation of antimicrobial resistance patterns based on the source of country origin of frozen shrimp revealed few inter-country resistant patterns found interconnecting and this influenced 44 (24.4%) isolates overlapping between isolates origin from frozen shrimp imported from China and Vietnam. This study documents the antimicrobial resistance in E. coli isolated from imported frozen shrimp and the presence of MDR E. coli in shrimp consuming communities, which may pose a risk to public health and the transfer of resistant bacteria to the food chain and environment.
- | ciprofloxacin oral / Generic mfg., nalidixic acid / Generic mfg., tetracycline / Generic mfg.
Journal: Molecular typing and antimicrobial susceptibility profiles of Campylobacter jejuni and Campylobacter coli Isolates from Patients and raw meat in Huzhou, China, 2021-2022. (Pubmed Central) - Dec 11, 2024
This study documents the antimicrobial resistance in E. coli isolated from imported frozen shrimp and the presence of MDR E. coli in shrimp consuming communities, which may pose a risk to public health and the transfer of resistant bacteria to the food chain and environment. Campylobacter is an important foodborne pathogen in both diarrheal patients and raw meat products in Huzhou City, exhibiting multiple antibiotic resistance and high level of genetic diversity.
- | Invanz (ertapenem) / Merck (MSD)
Journal: Emergence of Salmonella enterica Serovar Heidelberg Producing OXA 48 Carbapenemase in Eastern Algeria. (Pubmed Central) - Dec 6, 2024
Campylobacter is an important foodborne pathogen in both diarrheal patients and raw meat products in Huzhou City, exhibiting multiple antibiotic resistance and high level of genetic diversity. The strain was resistant to ertapenem (minimal inhibitory concentration [MIC] = 12
- | contragestazol (DL-111-IT) / Leadiant Biosci
Journal: Prevalence and Genomic Investigation of Salmonella Isolates Associated with Watermelons and Their Environmental Reservoirs in Bejaia, Algeria. (Pubmed Central) - Dec 3, 2024
Ten Salmonella isolates showed significant resistance to nalidixic acid, ofloxacin, and ciprofloxacin but were susceptible to all other antibiotics...Our study indicates a relatively high prevalence of Salmonella on watermelon samples before harvest. Although we cannot directly compare our results with previous studies, it is crucial to recognize that the absence of comprehensive comparative data underscores the need for further research and surveillance.
- | nalidixic acid / Generic mfg., rifampicin / Generic mfg., tetracycline / Generic mfg.
Journal: Identification of efflux pump inhibitors for Pseudomonas aeruginosa MexAB-OprM via ligand-based pharmacophores, 2D-QSAR, molecular docking, and molecular dynamics approaches. (Pubmed Central) - Dec 2, 2024
The predicted pharmacokinetic properties and toxicity of these compounds indicated their potential oral drugs. Multistep virtual screening of EPIs for MexAB-OprM, efflux pump multidrug resistant of P. aeruginosa.
- | nalidixic acid / Generic mfg., colistin sulphate / Generic mfg.
Journal: Description of two novel Corynebacterium species isolated from human nasal passages and skin. (Pubmed Central) - Nov 28, 2024
nov. MSK185 (GCF_030229765.1), C. yonathiae KPL2619 (GCF_037908465.1), and C. yonathiae MSK136 (GCF_022288805.2).
- | ciprofloxacin oral / Generic mfg., nalidixic acid / Generic mfg.
Journal: Antibiotic resistance and serotype distribution of Shigella strains in Bangladesh over the period of 2014-2022: evidence from a nationwide hospital-based surveillance for cholera and other diarrheal diseases. (Pubmed Central) - Nov 16, 2024
This emphasizes the urgency of prudent antibiotic use and improved hygiene. The findings provide crucial antimicrobial resistance patterns of Shigella species, highlighting the need for ongoing resistance monitoring and potentially informing future vaccine trials.
- | ampicillin / Generic mfg., nalidixic acid / Generic mfg., tetracycline / Generic mfg.
Journal: Trends in antimicrobial susceptibility patterns in Salmonella from human and nonhuman sources in Sao Paulo State, Brazil, 2016-2023. (Pubmed Central) - Nov 16, 2024
Extended-spectrum ?-lactamase production occurred in 4.4% of the isolates, of which Heidelberg configured the most prevalent extended-spectrum ?-lactamase-positive serotype. These findings underscore the importance of surveillance and effective monitoring to control this pathogen, highlighting the necessity of prioritizing public health efforts.
- | nalidixic acid / Generic mfg., tetracycline / Generic mfg.
Journal: Antibiotic contaminants and their impact in Gingee River, Puducherry: insights from SPE-UPLC-MS/MS and zebrafish study. (Pubmed Central) - Nov 14, 2024
These findings underscore the importance of surveillance and effective monitoring to control this pathogen, highlighting the necessity of prioritizing public health efforts. The concentrations of nalidixic acid, sulfamethoxazole, and tetracycline were determined to be 8.5, 6.9, and 4.8
- | Preclinical, Journal: Aldose reductase with quinolone antibiotics interaction: In vitro and in silico approach of its relationship with diabetic complications. (Pubmed Central) - Nov 13, 2024
The concentrations of nalidixic acid, sulfamethoxazole, and tetracycline were determined to be 8.5, 6.9, and 4.8 In this study, we evaluated the inhibitory potential of five quinolone antibiotics-gatifloxacin, lomefloxacin, nalidixic acid, norfloxacin, and sparfloxacin-as ARIs relevant to various physiological and pathological conditions...Our findings reveal that these quinolones moderately inhibit AR at micromolar concentrations, with inhibition constants (KIs) ranging from 1.03
- | Journal: Occurrence of antibiotic-resistant bacteria in the sea surface microlayer of coastal waters in the southern North Sea. (Pubmed Central) - Oct 29, 2024
A broth microdilution assay showed high minimum inhibitory concentrations (MICs) for most isolates for amikacin, aztreonam, ceftazidime, cefepime, minocycline, and tobramycin...Over 50?% of these genes are multidrug efflux pumps. Our study shows that the SML in anthropogenic-influenced coastal regions harbors a wide diversity of antibiotic-resistant bacteria equipped with a broad range of multidrug efflux pumps.
- | Journal: Antimicrobial Resistance Profiles of E. coli Isolated From Pooled Samples of Sick, Farm, and Market Chickens in Nairobi County, Kenya. (Pubmed Central) - Oct 28, 2024
Very few isolates were resistant to Amoxicillin and Gentamicin (each at 3.7%), Ampicillin (11.1%), and Nalidixic acid (24.1%)...This information will augment current data on the AMR status of bacteria harbored by chickens in Kenya. It will also inform policymakers in their fight against AMR.
- | ampicillin / Generic mfg., nalidixic acid / Generic mfg., trimethoprim/sulfamethoxazole / Generic mfg.
Journal: Multidrug-resistant Salmonella Typhi among symptomatic and asymptomatic children in informal settlements in Nairobi, Kenya. (Pubmed Central) - Oct 26, 2024
The carriage of MDR S. Typhi among the asymptomatic children is concerning as they can act as potential transmitters of the typhoid disease to unsuspecting children. These study findings highlight the need for continued surveillance of antimicrobial resistance and mass immunization of children living in these urban informal areas.
- | Journal: Serotype Distribution and Antimicrobial Resistance of Salmonella Isolates from Poultry Sources in China. (Pubmed Central) - Oct 25, 2024
These study findings highlight the need for continued surveillance of antimicrobial resistance and mass immunization of children living in these urban informal areas. This study revealed a high percentage of multidrug-resistant Salmonella from poultry sources, stressing the importance of continuous monitoring of Salmonella serotypes and antimicrobial resistance in the poultry chain, and emergency strategies should be implemented to address this problem.
- | Journal: Investigating the resistome of haemolytic bacteria in Arctic soils. (Pubmed Central) - Oct 23, 2024
belong to 33% non-wild type (NWT) for erythromycin and penicillin and 22% NWT for tetracycline...belong to 43% NWT for nalidixic acid and streptomycin and 29% NWT for colistin...Our research demonstrates the presence of antimicrobial resistance in bacteria from Arctic habitats and highlights the importance of conservation efforts in these environments, where anthropogenic influence is becoming more evident. Furthermore, our data suggest the possible presence of novel resistance mechanisms, which could pose a threat if the responsible genes are transferable between species or become widespread due to environmental stress and alterations brought about by climate change.
- || Retrospective data, Review, Journal: Antimicrobial Resistance of Environmental V. cholerae Non-O1/O139 Isolates: Systematic Review and Meta-analysis. (Pubmed Central) - Oct 23, 2024
Furthermore, our data suggest the possible presence of novel resistance mechanisms, which could pose a threat if the responsible genes are transferable between species or become widespread due to environmental stress and alterations brought about by climate change. The meta-analysis showed significant variability in antibiotic resistance patterns among environmental NOVC isolates across time and regions, emphasizing the need for tar-geted, time-specific, and country-specific approaches to address antibiotic resistance globally.
- | Journal, Gram negative: Prevalence of Resistance Genes Among Multidrug-Resistant Gram-Negative Bacteria Isolated from Waters of Rivers Swat and Kabul, Pakistan. (Pubmed Central) - Oct 22, 2024
The prevalence of bla-TEM gene was 72% (n = 36), aadA gene 34% (n = 17), sul gene 32% (n = 16), bla-CTXM gene 12% (n = 6), int gene 66% (n = 33), and int1 gene 6% (n = 3). This information highlights the need for controlling and monitoring the release of domestic wastes to rivers.
- | Journal: Antimicrobial resistance of Salmonella isolates from cattle and horses with salmonellosis in Hokkaido, Japan. (Pubmed Central) - Oct 17, 2024
Among 16 equine isolates, no resistance was observed to cefazolin, cefotaxime, gentamicin, nalidixic acid, ciprofloxacin, colistin, or chloramphenicol. Gentamicin and kanamycin are recommended as the first-line treatment for salmonellosis in cattle, with fluoroquinolones as the second choice.