Neoplastic Processes
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 150 Companies   247 Products   247 Products   139 Mechanisms of Action   7 Trials   1806 News 


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  • ||||||||||  Trial completion:  Radiofrequency Ablation in Resectable Colorectal Lung Metastasis (clinicaltrials.gov) -  Mar 7, 2019   
    P2,  N=70, Completed, 
    Recruiting --> Completed | Trial completion date: Apr 2019 --> Jan 2019 | Trial primary completion date: Apr 2018 --> Jan 2019 Active, not recruiting --> Completed
  • ||||||||||  Thymoglobulin (anti-thymocyte globulin (rabbit)) / Sanofi, Rituxan (rituximab) / Roche
    Enrollment change, Trial termination:  Rituximab in Preventing Acute Graft-Versus-Host Disease in a Donor Stem Cell Transplant for Hematologic Cancer (clinicaltrials.gov) -  Feb 26, 2019   
    P2,  N=20, Terminated, 
    Active, not recruiting --> Completed | Trial completion date: Jan 2019 --> Aug 2018 N=50 --> 20 | Active, not recruiting --> Terminated; Study was closed to accrual for safety related to the frequency of BK infections.
  • ||||||||||  Trial completion, Surgery:  Stereotactic Radiosurgery for Patients With Hepatic Metastases. (clinicaltrials.gov) -  Feb 16, 2019   
    P1,  N=27, Completed, 
    N=50 --> 20 | Active, not recruiting --> Terminated; Study was closed to accrual for safety related to the frequency of BK infections. Active, not recruiting --> Completed
  • ||||||||||  Avastin (bevacizumab) / Roche
    Trial completion, Metastases:  AXEPT: A Phase III Study of 2nd-line XELIRI  (clinicaltrials.gov) -  Jan 8, 2019   
    P3,  N=650, Completed, 
    The first chemotherapy become a standard for patients with NSCL with asymptomatic brain metastases. Active, not recruiting --> Completed
  • ||||||||||  Trial completion, Enrollment change, Trial completion date:  Stereotactic Radiation Therapy in Treating Patients With Liver Metastases (clinicaltrials.gov) -  Oct 10, 2018   
    P1,  N=9, Completed, 
    Trial completion date: Apr 2014 --> Feb 2017 Active, not recruiting --> Completed | N=18 --> 9 | Trial completion date: Sep 2018 --> Apr 2016
  • ||||||||||  Sutent (sunitinib) / Pfizer
    Trial completion, Trial completion date, Trial primary completion date, Metastases:  Perfusion CT as a Predictor for Response to Antiangiogenic Therapy in Patients With Metastasized Renal Cell Carcinoma (clinicaltrials.gov) -  Oct 2, 2018   
    P=N/A,  N=60, Completed, 
    Trial completion date: Sep 2018 --> Sep 2019 | Trial primary completion date: May 2018 --> May 2019 Recruiting --> Completed | Trial completion date: Jan 2018 --> Jul 2018 | Trial primary completion date: Jan 2016 --> Jul 2018
  • ||||||||||  lisinopril / Generic mfg.
    Trial completion, Enrollment change, Trial completion date, Trial primary completion date:  Dose Titration of Lisinopril in Children Aged 1 to 18 Years With Primary or Secondary Hypertension (clinicaltrials.gov) -  Sep 20, 2018   
    P4,  N=13, Completed, 
    Recruiting --> Completed | Trial completion date: Jan 2018 --> Jul 2018 | Trial primary completion date: Jan 2016 --> Jul 2018 Recruiting --> Completed | N=33 --> 13 | Trial completion date: Jan 2016 --> Sep 2018 | Trial primary completion date: Sep 2015 --> May 2017
  • ||||||||||  Trial completion, Trial completion date, Trial primary completion date, Metastases:  Dose Escalation of Hypofractionated Radiation Therapy in Patients With Metastatic Cancer (clinicaltrials.gov) -  Sep 12, 2018   
    P1,  N=63, Completed, 
    Trial primary completion date: Jul 2020 --> Apr 2016 Active, not recruiting --> Completed | Trial completion date: Jun 2018 --> Mar 2018 | Trial primary completion date: Jun 2018 --> Mar 2018
  • ||||||||||  Avastin (bevacizumab) / Roche
    Enrollment change, Trial termination:  Avastin and Doxorubicin Postoperatively for Patients With Anaplastic Thyroid Cancer (clinicaltrials.gov) -  Aug 28, 2018   
    P2,  N=15, Terminated, 
    Active, not recruiting --> Completed | Trial completion date: Jun 2018 --> Mar 2018 | Trial primary completion date: Jun 2018 --> Mar 2018 N=30 --> 15 | Active, not recruiting --> Terminated; lack of response
  • ||||||||||  Biomarker, Trial termination, Tumor cell, Metastases:  Cancer Stem Cell Markers and Prognostic Markers in Circulating Tumor Cells (clinicaltrials.gov) -  Aug 20, 2018   
    P=N/A,  N=33, Terminated, 
    N=30 --> 15 | Active, not recruiting --> Terminated; lack of response Completed --> Terminated; PI left Institution
  • ||||||||||  crenigacestat (LY3039478) / Eli Lilly, BMS
    Trial completion, Metastases:  A Study of LY3039478 in Participants With Advanced Cancer (clinicaltrials.gov) -  Aug 7, 2018   
    P1,  N=237, Completed, 
    Suspended --> Completed | N=88 --> 8 | Trial completion date: Mar 2019 --> Jun 2017 Active, not recruiting --> Completed
  • ||||||||||  Enrollment change, Trial completion date, Trial termination, Trial primary completion date:  ALPPS (Liver Partition and Portal Vein Ligation) for Two-stage Hepatectomy for Colorectal Liver Metastasis (clinicaltrials.gov) -  Aug 2, 2018   
    P3,  N=3, Terminated, 
    Active, not recruiting --> Completed | Trial completion date: Dec 2018 --> Aug 2018 | Trial primary completion date: Dec 2018 --> Aug 2018 N=44 --> 3 | Recruiting --> Terminated | Trial completion date: Dec 2017 --> Dec 2016 | Trial primary completion date: Dec 2017 --> Dec 2016; Main reason: negative echo in the literature after the first publications.
  • ||||||||||  crenigacestat (LY3039478) / Eli Lilly, BMS
    Trial completion date, Metastases:  A Study of LY3039478 in Participants With Advanced Cancer (clinicaltrials.gov) -  Apr 24, 2018   
    P1,  N=282, Active, not recruiting, 
    Active, not recruiting --> Completed Trial completion date: Mar 2018 --> Jun 2018