Neoplastic Processes MOAs - LARVOL Sigma

Neoplastic Processes

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139 Mechanisms of Action


Phase N/A 1 2 3 4 Products		0	5										10										15										20										25										30										35										40										45										50



VEGFR inhib




Purinergic receptor P1 agon




CD20 inhib




CDK inhib




DNA inhib




EGFR inhib




VEGF-A inhib




Tubulin inhib




CD3 agon




HDAC2 inhib




c-KIT inhib




PDGFR α antag




GnRH stim




pan-HER inhib




AKT inhib




IFNα stim




IGF-1R inhib




GCR agon




PIGF inhib




TIE-2 inhib




BRAF V600E inhib




Bcl2 inhib




Bcl2 inhib




CCR5 receptor antag




GnRH stim




IL-6 inhib




JAK1 inhib




TNFα inhib




mTOR inhib




µ-opioid agon




CD20 inhib




CDK inhib




Endothelin A receptor antag




GM-CSF agon




Histamine receptor agon




Immunosuppressant




PARP1 inhib




PI3K inhib




TLR8 agon




pan-HER inhib




Apoptosis inducer




Beta radiation emitter




CTLA4 inhib




Calcineurin inhib




Estrogen receptor mod




FGFR3 inhib




HIF-1 inhib




HSP90 inhib




IL-12 inhib




IL-2 stim