Immunoproliferative Disorders MOAs

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Phase N/A 1 2 3 4 Products	0	12	24	36	48	60	72	84	96	108	120



CD20 inhib




FGFR1 inhib




CD19 inhib




Bifunctional alkylating agent




BRAF inhib




DNA PK inhib




VEGFR inhib




KIR receptor antag




HDAC inhib




IL-11 stim




Microtubule inhib




c-KIT inhib




CD20 inhib




PDGFR α-β inhib




PI3K inhib




mTOR inhib




Aurora kinase A inhib




CDK inhib




CD22-targeted antibody-drug conjugate




FGFR2 inhib




AKT inhib




EGFR inhib




IGF-1R inhib




TIE-2 inhib




Bcl2 inhib




Bcl2 inhib




IFNα stim




Apoptosis stim




GCR agon




IL-2 stim




PD-L1 inhib




Estrogen receptor mod




HSP90 inhib




Hedgehog cell-signalling pathway inhib




IL-1β inhib




IL-6 inhib




JAK2 inhib




Proteasome inhib




TNFα inhib




µ-opioid agon




DNA PK inhib




IL-8 inhib




Immunosuppressant




PIGF inhib




PPAR γ agon




Survivin inhib




TRAIL R1 agon




BRAF inhib




HIF-1α inhib




Insulin receptor agon



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