 |
Diseases |  |
Trials |
|
Trials |  |
News |  |
- | PRG-A-01 / PRG S&Tech
Preclinical, Journal: Novel chemical inhibitor against SOD1 misfolding and aggregation protects neuron-loss and ameliorates disease symptoms in ALS mouse model. (Pubmed Central) - Jan 11, 2022
Administration of PRG-A01 into the ALS model mouse resulted in significant improvement of muscle strength, motor neuron viability and mobility with extended lifespan. These results suggest that SOD1 misfolding/aggregation is a potent therapeutic target for SOD1 related ALS.