- |||||||||| topotecan episcleral / 3T Ophthalmics
Enrollment closed, Trial completion date, Trial primary completion date: Topotecan Episcleral Plaque for Treatment of Retinoblastoma (clinicaltrials.gov) - Oct 31, 2023
P1, N=42, Active, not recruiting,
Recruiting --> Active, not recruiting | Trial completion date: Oct 2023 --> Oct 2024 | Trial primary completion date: Oct 2023 --> Oct 2024
- |||||||||| topotecan episcleral / 3T Ophthalmics
Enrollment change: Topotecan Episcleral Plaque for Treatment of Retinoblastoma (clinicaltrials.gov) - Apr 21, 2023
P1, N=42, Recruiting,
Recruiting --> Active, not recruiting | Trial completion date: Oct 2023 --> Oct 2024 | Trial primary completion date: Oct 2023 --> Oct 2024 N=30 --> 42
- |||||||||| topotecan episcleral / 3T Ophthalmics
Journal: Atypical anterior retinoblastoma: diagnosis by aqueous humor cell-free DNA analysis. (Pubmed Central) - Nov 4, 2022
Stable regression was achieved to 28-month follow-up, with no detectable aqueous cell-free DNA. RB1 sequencing analysis of tumor-derived cell-free DNA from aqueous humor can confirm the diagnosis of retinoblastoma in cases of diagnostic uncertainty.
- |||||||||| topotecan episcleral / 3T Ophthalmics
Enrollment open, Enrollment change, Trial completion date, Trial primary completion date: Topotecan Episcleral Plaque for Treatment of Retinoblastoma (clinicaltrials.gov) - Jul 7, 2021
P1, N=30, Recruiting,
The results from the pilot experiment constitute the proof of principle for the use of the proposed implants as a drug delivery system for the local treatment of intraocular diseases. Not yet recruiting --> Recruiting | N=12 --> 30 | Trial completion date: Oct 2021 --> Oct 2023 | Trial primary completion date: Oct 2021 --> Oct 2023
- |||||||||| topotecan episcleral / 3T Ophthalmics
Enrollment open: STEP-RB: Topotecan Episcleral Plaque for Treatment of Retinoblastoma (clinicaltrials.gov) - Jun 25, 2020
P1, N=30, Recruiting,
Not yet recruiting --> Recruiting | N=12 --> 30 | Trial completion date: Oct 2021 --> Oct 2023 | Trial primary completion date: Oct 2021 --> Oct 2023 Not yet recruiting --> Recruiting
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