||||||||||RB-HBV008 / Suzhou Ribo Journal: Ionizable liposomal siRNA therapeutics enables potent and persistent treatment of Hepatitis B. (Pubmed Central) - Mar 25, 2022 Moreover, the toxicity profiles suggested satisfactory safety outcomes with ten times the therapeutic window. Therefore, this study provides an effective nucleic acid delivery system and a promising RNAi agent for the treatment of hepatitis B.