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[VIRTUAL] SCABIES MANAGEMENT IN CHILDREN IN SWITZERLAND () - Jun 2, 2021 - Abstract #ESPID2021ESPID_1526; Management is heterogeneous as non-dermatologists use Ivermectin reluctantly. Research priorities include convenient diagnostic tools, a child-appropriate, oral Ivermectin formulation and optimized dosing and treatment protocols.
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[VIRTUAL] Meta-analysis of randomized trials of ivermectin to treat SARS-CoV-2 infection () - May 27, 2021 - Abstract #IASHIV2021IAS_HIV_1221; This meta-analysis showed a 73% improvement in survival, faster time to clinical recovery and signs of a dose-dependent effect of viral clearance for patients given ivermectin versus control. Although preliminary findings are encouraging, further evidence from larger and higher-quality studies are warranted before ivermectin can be justified for approval.
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Enrollment closed: RIMDAMAL II: Repeat Ivermectin Mass Drug Administrations for MALaria Control II (clinicaltrials.gov) - May 26, 2021 P3, N=4088, Active, not recruiting, Although preliminary findings are encouraging, further evidence from larger and higher-quality studies are warranted before ivermectin can be justified for approval. Recruiting --> Active, not recruiting
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Trial completion date, Trial primary completion date: ISSC: Ivermectin Safety in Small Children (clinicaltrials.gov) - May 25, 2021 P2, N=400, Not yet recruiting, Recruiting --> Active, not recruiting Trial completion date: Oct 2021 --> Dec 2022 | Trial primary completion date: Oct 2021 --> Oct 2022
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Journal: Ivermectin in the management of a scabies outbreak in a long-term care facility. (Pubmed Central) - May 20, 2021 Bernigaud et al. reported on the COVID-19 related outcomes in the 69 residents (median age 90 years) of an LTCF who had received two doses of oral ivermectin 200 μg kg between 6 March 2020 and the 20 March 2020 to control an outbreak of scabies.
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Trial completion date, Trial primary completion date: COVID-OUT: Early Outpatient Treatment for SARS-CoV-2 Infection (COVID-19) (clinicaltrials.gov) - May 19, 2021 P2/3, N=1160, Recruiting, reported on the COVID-19 related outcomes in the 69 residents (median age 90 years) of an LTCF who had received two doses of oral ivermectin 200 μg kg between 6 March 2020 and the 20 March 2020 to control an outbreak of scabies. Trial completion date: Aug 2021 --> Dec 2021 | Trial primary completion date: Jun 2021 --> Oct 2021
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Trial completion date, Trial primary completion date: COVidIVERmectin: Ivermectin for Treatment of Covid-19 (clinicaltrials.gov) - May 17, 2021 P2, N=102, Recruiting, Trial completion date: Aug 2021 --> Dec 2021 | Trial primary completion date: Jun 2021 --> Oct 2021 Trial completion date: May 2021 --> Sep 2021 | Trial primary completion date: Feb 2021 --> Jun 2021
- |||||||||| Clinical, Journal: Use of Permethrin in the Treatment of Rosacea Fulminans During Pregnancy: One Case Report. (Pubmed Central) - May 15, 2021
We consider that 5% permethrin cream could be an effective, cheap and safe treatment not only in regular patients with rosacea but also in pregnant women, representing an important alternative in the context of pregnancy when therapeutic options are limited. To our knowledge this is the first case of rosacea treated with 5% permethrin cream in monotherapy during pregnancy.
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Trial completion date, Trial primary completion date, Combination therapy: Trial of Combination Therapy to Treat COVID-19 Infection (clinicaltrials.gov) - May 13, 2021 P2, N=30, Recruiting, • The profile of mycobiota provides essential data that were previously absent. Trial completion date: Jul 2021 --> Jul 2022 | Trial primary completion date: May 2021 --> May 2022
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New P2/3 trial: Ivermectina Colombia (IVERCOL) (clinicaltrials.gov) - May 13, 2021 P2/3, N=966, Not yet recruiting,
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Clinical, Journal: Demodex blepharokeratoconjunctivitis affecting young patients: A case series. (Pubmed Central) - May 11, 2021 All patients were treated with 50% tea tree oil lid scrubs and two doses of oral ivermectin (200 mcg/kg)...Viral keratitis and allergic conjunctivitis are common misdiagnoses and demodicosis can be confirmed by simple epilation. Early diagnosis and treatment can prevent long-term steroid use and its related complications.
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Clinical, Journal: Acute inflammatory Demodex-induced pustulosis in an immunocompetent patient related to topical steroid use. (Pubmed Central) - Apr 28, 2021 Though usually clinically insignificant, demodicosis may be associated with a wide spectrum of skin diseases in immunocompetent hosts, such as erythematotelangiectatic and papulopustular rosacea, Demodex folliculorum, and blepharitis. We present a case of a healthy 9-year-old boy with an exuberant, inflammatory, Demodex-associated pustular eruption of the face, induced by the use of a high-potency topical steroid and successfully treated with oral ivermectin.
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[VIRTUAL] Good night, sleep tight, don’t let the Cimex bite. () - Apr 10, 2021 - Abstract #AADVMX2021AAD_VMX_539; He was given oral ivermectin 200mg twice...We believe this may be the first documented case of bed bugs colonizing organic human tissue. We also described a proposed treatment option for similar patients.
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