ivermectin oral / Generic mfg. 
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  • ||||||||||  Daklinza (daclatasvir) / BMS
    Journal:  Molecular modelling studies unveil potential binding sites on human serum albumin for selected experimental and in silico COVID-19 drug candidate molecules. (Pubmed Central) -  Sep 23, 2021   
    The strong HSA binding drug candidates consist of fourteen molecules (Saquinavir, Ritonavir, Dihydroergotamine, Daclatasvir, Paritaprevir etc.) with binding energies ranging from -9.7 to -12.1 kcal/mol...Further, the stability of the HSA-ligand complexes was analyzed through 100 ns molecular dynamics simulations considering various geometric properties. The binding free energy between free HSA and compounds were calculated using Molecular mechanics Poisson-Boltzmann surface area (MM/PBSA) and molecular mechanics generalized Born surface area (MM/GBSA) approach. The findings of this study might be useful in understanding the mechanism of COVID-19 drug candidates binding to serum albumin protein, as well as their pharmacodynamics and pharmacokinetics.
  • ||||||||||  ivermectin oral / Generic mfg.
    STRONGYLOIDES STERCORALIS HYPERINFECTION SYNDROME IN A PATIENT UNDERGOING KIDNEY TRANSPLANT () -  Sep 23, 2021 - Abstract #ESOT2021ESOT_1823;    
    Patients from tropical and subtropical areas should be screened for S. Stercoralis as they are potential healthy carriers of the parasite. In the event of a diagnosis of post-transplant infection, it is essential to investigate the presence of systemic dissemination by adapting the therapy to the patient's immunosuppression picture.
  • ||||||||||  dexamethasone / Generic mfg., ivermectin oral / Generic mfg.
    Journal:  Variation in therapeutic strategies for the management of severe COVID-19 in India- A nationwide cross-sectional survey. (Pubmed Central) -  Sep 23, 2021   
    In the event of a diagnosis of post-transplant infection, it is essential to investigate the presence of systemic dissemination by adapting the therapy to the patient's immunosuppression picture. There is a considerable variation in the physicians' choice of therapeutic strategies for the management of severe COVID-19 in India, as compared with the available evidence.
  • ||||||||||  ivermectin oral / Generic mfg.
    Journal:  Helminth infections in Italian donkeys: Strongylus vulgaris more common than Dictyocaulus arnfieldi. (Pubmed Central) -  Sep 22, 2021   
    The mean number of anthelmintic treatments/year was 1.4; most of the donkeys (71.8%) were dewormed using an ivermectin drug. It is important to design parasite programs to specifically address both D. arnfieldi and S. vulgaris in donkeys, and this is especially important if donkeys co-graze with horses.
  • ||||||||||  camostat mesilate / Generic mfg., hydroxychloroquine / Generic mfg., ivermectin oral / Generic mfg.
    Journal:  Comprehensive Cardiotoxicity Assessment of COVID-19 Treatments Using Human Induced Pluripotent Stem Cell-derived Cardiomyocytes. (Pubmed Central) -  Sep 22, 2021   
    Hydroxychloroquine induced early after depolarization, while remdesivir, favipiravir, camostat, and ivermectin had little effect on field potentials...Our data suggest that hydroxychloroquine has proarrhythmic risk and other drugs have low proarrhythmic risk. Thus, hiPSC-CMs represent a useful tool for assessing the comprehensive cardiotoxicity caused by COVID-19 treatments in non-clinical settings.
  • ||||||||||  ivermectin oral / Generic mfg.
    PK/PD data, Journal:  Interactions of anti-COVID-19 drug candidates with hepatic transporters may cause liver toxicity and affect pharmacokinetics. (Pubmed Central) -  Sep 22, 2021   
    In the present work we have examined the in vitro interactions of some key repurposed drugs advocated to treat COVID-19 (lopinavir, ritonavir, ivermectin, remdesivir and favipiravir), with the key drug transporters of hepatocytes...Favipiravir had no significant effect on any of these transporters. Since both general drug metabolism and drug-induced liver toxicity are strongly dependent on the functioning of these transporters, the various interactions reported here may have important clinical relevance in the drug treatment of this viral disease and the existing co-morbidities.