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[VIRTUAL] Ivermectin-Induced ANCA Vasculitis () - Oct 17, 2021 - Abstract #KIDNEYWEEK2021KIDNEY_WEEK_2619; He received prednisone 1mg/kg,3 biweekly doses of intravenous cyclophosphamide, 10 doses of plasmapheresis, and was initiated on dialysis...Commonly implicated drugs are hydralazine, levamisole-contaminated cocaine, propylthiouracil, allopurinol. Although no case of Ivermectin-induced AAV has been reported, we recommend a high index of suspicion as prompt cessation of the offending drug can significantly improve prognosis in drug-associated AAV.
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[VIRTUAL] SEVERE COVID-19 PNEUMONIA IN A FULLY VACCINATED IMMUNOCOMPROMISED PATIENT () - Oct 13, 2021 - Abstract #CHEST2021CHEST_1431; Though widespread immunization against COVID-19 is underway, patients with hematological malignancies still remain a vulnerable population. The decision to halt immunomodulatory therapy to improve efficacy of the vaccine needs further investigation.
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[VIRTUAL] PULMONARY STRONGYLOIDIASIS IN TREATED MULTIPLE SCLEROSIS () - Oct 13, 2021 - Abstract #CHEST2021CHEST_1270; We add to the literature a case of disseminated Strongyloides infection in a patient on Ocrelizumab likely even precipitated by a short course of steroids. Severe eosinophilic acute disease with acute pulmonary findings should highly raise the suspicion for disseminated parasitic disease in patients treated with new monoclonal agents and receiving steroid therapy.
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[VIRTUAL] A CASE OF DISSEMINATED STRONGYLOIDIASIS DURING TREATMENT FOR COVID-19 () - Oct 13, 2021 - Abstract #CHEST2021CHEST_1246; Disseminated strongyloidiasis can be detrimental in patients with COVID-19. In the setting of a global pandemic during which one of the mainstays of treatment is high dose glucocorticoids, it is important to be cognizant of dormant infections like Strongyloides that may become unmasked during treatment.
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[VIRTUAL] OLD MEDICINE FOR NEW PROBLEMS: POTENTIAL ROLE OF A NOVEL TREATMENT USING NEBULIZED HEPARIN IN COVID-19 ARDS () - Oct 13, 2021 - Abstract #CHEST2021CHEST_714; Treatment was started with oxygen, dexamethasone, convalescent plasma, ivermectin, remdesivir, and nebulized heparin...Patient 3 72 year old female (BMI 46) with a history of COPD, obstructive sleep apnea, atrial fibrillation treated with Apixaban, DVT, aortic stenosis, and congestive heart failure presented with shortness of breath and cough...Historically nebulized heparin was used in inhalation injury. As seen in this case can be a novel and effective treatment option for COVD-19 pneumonia.
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Clinical, Journal: Recording drug responses from adult Dirofilaria immitis pharyngeal and somatic muscle cells. (Pubmed Central) - Oct 13, 2021 We also demonstrate that the somatic muscle cells have robust responses to 30 μM acetylcholine, levamisole, pyrantel and nicotine. This is important preliminary data, demonstrating the feasibility of electrophysiological studies in this important parasite.
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Journal: Comparison of electrophysiological and motility assays to study anthelmintic effects in Caenorhabditis elegans. (Pubmed Central) - Oct 13, 2021 As references, we used three macrocyclic lactones (ivermectin, moxidectin, and milbemycin oxime), and levamisole, which act on different ion channels...Drug effects on pump timing and EPG waveforms were also investigated. These experiments confirmed drug-class specific effects of the tested anthelmintics and illustrated the relative strengths and limitations of the different assays for anthelmintic research.
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Retrospective data, Journal: Bias Possibility in a Retrospective Study of Ivermectin for COVID-19 (Pubmed Central) - Oct 12, 2021 These experiments confirmed drug-class specific effects of the tested anthelmintics and illustrated the relative strengths and limitations of the different assays for anthelmintic research. No abstract available
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