ivermectin oral / Generic mfg. 
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  • ||||||||||  metformin / Generic mfg., ivermectin oral / Generic mfg., fluvoxamine / Generic mfg.
    Enrollment closed, Trial primary completion date:  COVID-OUT: Early Outpatient Treatment for SARS-CoV-2 Infection (COVID-19) (clinicaltrials.gov) -  Mar 7, 2022   
    P3,  N=1350, Active, not recruiting, 
    Recruiting --> Active, not recruiting | Trial primary completion date: Feb 2022 --> Feb 2023
  • ||||||||||  ivermectin oral / Generic mfg.
    Journal:  Persisting itching? Consider scabies (Pubmed Central) -  Mar 4, 2022   
    Although resistance to these agents has been suggested, treatment failure is mainly caused by failure to properly implement the treatment recommendations by the patient and/or his or her contacts. We present three patients with scabies in which the diagnosis and treatment could have been performed better.
  • ||||||||||  ivermectin oral / Generic mfg., albendazole / Generic mfg.
    Clinical, Journal:  Case Report: Challenges for the Diagnosis and Treatment of Strongyloides stercoralis in Chronic Obstructive Pulmonary Disease Patients. (Pubmed Central) -  Mar 3, 2022   
    All the included patients were treated with albendazole, which is the second-line drug for S. stercoralis, and relapse of infection was observed in two patients by passing few months from the treatment...In COPD patients who are receiving steroids, screening and follow-up for strongyloidiasis should be considered as priorities. In addition, ivermectin, which is the first-line drug for strongyloidiasis, should be available in the region.
  • ||||||||||  ivermectin oral / Generic mfg.
    Journal:  Multi-drug Treatment for COVID-19-induced Acute Respiratory Distress Syndrome (Pubmed Central) -  Mar 3, 2022   
    Recently, the anti-SARS-CoV-2 activities of tetracyclines, macrolide antibiotics, and ivermectin (IVM), have attracted considerable attention for their potential as a single or multi-drug treatment regimen...COVID-19 is characterized by early exponential viral replication, cytokine storm-associated organ damage, including acute respiratory distress syndrome (ARDS) and thrombosis. Considering anti-inflammatory and immunomodulatory effects of the aforementioned drugs and corticosteroids, early treatment with doxycycline, azithromycin, IVM, and corticosteroids is thought to be the most promising option for combating COVID-19-induced ARDS.
  • ||||||||||  ivermectin oral / Generic mfg.
    Sorry, stromectol (Twitter) -  Mar 2, 2022   
  • ||||||||||  ivermectin oral / Generic mfg.
    Trial completion date, Trial primary completion date:  A Phase III Confirmatory Study of K-237 (clinicaltrials.gov) -  Mar 2, 2022   
    P3,  N=1000, Recruiting, 
    Considering anti-inflammatory and immunomodulatory effects of the aforementioned drugs and corticosteroids, early treatment with doxycycline, azithromycin, IVM, and corticosteroids is thought to be the most promising option for combating COVID-19-induced ARDS. Trial completion date: Mar 2022 --> Sep 2022 | Trial primary completion date: Mar 2022 --> Sep 2022
  • ||||||||||  ivermectin oral / Generic mfg., albendazole / Generic mfg.
    Clinical, Journal:  Effect of antihelminths with contrasting efficacy against gastrointestinal nematodes on the live-weight gain of young Nellore cattle. (Pubmed Central) -  Mar 1, 2022   
    In most of the samplings, the median EPGs were significantly lower (P < 0.05) in the group treated with albendazole...Because the main difference between the ivermectin and the control groups was the O. radiatum parasitism, most of the losses in the control group were possibly due to this nematode species. Nevertheless, the other nematodes species that occurred in relatively high intensities in control group could also have an additive effect in such losses.
  • ||||||||||  ivermectin oral / Generic mfg.
    Journal:  Prevalence of anthelmintic resistant cyathostomins in Prince Edward Island, Canada. (Pubmed Central) -  Mar 1, 2022   
    Once individual FEC were ≥ 200 EPG, horses were dewormed with 0.2 mg/kg of ivermectin orally (n = 80), and FEC were performed every 2-3 weeks for seven weeks...The prevalence of Strongylus vulgaris among individual horses in this study was 2.8% and was detected on 2/14 farms. These findings will allow us to educate owners and veterinarians on appropriate anthelmintic protocols in PEI and can be used as a baseline for continued monitoring of ERP and anthelmintic resistance in this region.
  • ||||||||||  ivermectin oral / Generic mfg.
    Journal:  Synthesis and antiplasmodial activity of regioisomers and epimers of second-generation dual acting ivermectin hybrids. (Pubmed Central) -  Mar 1, 2022   
    Successful isolation of regioisomers and epimers has been demonstrated, and the evaluation of their in vitro antiplasmodial activity against both the blood stages of P. falciparum and the hepatic stages of P. berghei have been undertaken. These compounds displayed structure-dependent antiplasmodial activity, in the nM range, which was more potent than that of IVM, its aglycon or primaquine, highlighting the superiority of this hybridization strategy in designing new antiplasmodial agents.
  • ||||||||||  Vistide (cidofovir) / Gilead
    Preclinical, Journal:  The in vitro Evaluation of the Activity of COVID-19 Antiviral Drugs Against Adenovirus. (Pubmed Central) -  Mar 1, 2022   
    The 50% effective concentrations (EC) of remdesivir (REM), hydroxychloroquine (HCQ), ivermectin (IVM), umifenovir (UMF) and cidofovir (CDV) (positive antiviral control) were determined for the human HAdV types HAdV3, HAdV4, HAdV5, HAdV7a, HAdV8, HAdV19/64 and HAdV37 using standard plaque-reduction assays in A549 cells...The anti-adenovirus activity of HCQ could not be determined due to cytotoxicity. Further investigation of REM, UMF, and IVR as antivirals for adenovirus is indicated.