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Journal: Nanovectorization of Ivermectin to avoid overdose of drugs. (Pubmed Central) - Apr 27, 2022 To answer this general question, we propose, using simulations, to show that the nanovectorization of Ivermectin on BN oxide nanosheets can increase the transfer of the drug to its target and thus decrease the quantity of drug necessary to cope with the disease. This first application could help science to develop such nanocargo to avoid adverse effects.Communicated by Ramaswamy H. Sarma.
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Journal: Grazier perceptions and management practices for liver fluke control in north eastern NSW, Australia. (Pubmed Central) - Apr 26, 2022 This current survey has revealed that graziers rely on anthelmintics as their primary choice for liver fluke control. Reluctance to adopt IPM strategies and a continued heavy reliance on TCBZ, whilst basing anthelmintic decisions on perception rather than measurement and testing, pose threats for the future control of liver fluke in livestock within this endemic area.
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Journal: Antiviral Activity of Repurposing Ivermectin against a Panel of 30 Clinical SARS-CoV-2 Strains Belonging to 14 Variants. (Pubmed Central) - Apr 24, 2022 Unlike chloroquine (EC from 4.3 ± 2.5 to 29.3 ± 5.2 µM) or remdesivir (EC from 0.4 ± 0.3 to 25.2 ± 9.4 µM), ivermectin showed a relatively homogeneous in vitro activity against SARS-CoV-2 regardless of the strains or variants (EC from 5.1 ± 0.5 to 6.7 ± 0.4 µM), except for one omicron strain (EC = 1.3 ± 0.5 µM)...EC = 201, mean EC = 11.9 ± 10.0 µM) (p = 1.6 × 10). These results should be interpreted with caution regarding the potential use of ivermectin in SARS-CoV-2-infected patients: it is difficult to translate in vitro study results into actual clinical treatment in patients.
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Review: Persistent Hiccups as an Atypical Presentation of SARS-CoV-2 Infection: A Systematic Review of Case Reports. (Pubmed Central) - Apr 22, 2022 Equally, 44% of patients (7/16) received dexamethasone followed by azithromycin (5/16), ivermectin (4/16), and ceftriaxone (4/16) for managing the infection from SARS-CoV-2...Persistent hiccups are possibly a rare symptom that clinicians may expect to encounter in patients infected with SARS-CoV-2. Although there is not ample proof to propose causation, increased awareness about the diversity of presentations of SARS-CoV-2 infection could be crucial in the early recognition of the disease.
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HEAD LICE INFESTATION - AN UNUSUAL CAUSE OF IRON DEFICIENCY ANEMIA IN A 13-YEAR-OLD FEMALE () - Apr 20, 2022 - Abstract #ASPHO2022ASPHO_200; Severe IDA secondary to Pediculosis capitis should be a diagnosis of exclusion. Having ruled out possible red blood cell production and consumption pathologies, we were left with blood loss secondary to lice infestation as the only potential cause of anemia in this child.
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Journal: Effects of ivermectin treatment of backyard chickens on mosquito dynamics and West Nile virus transmission. (Pubmed Central) - Apr 20, 2022 The measurement of changes in enzymatic activity and the in vitro TPI enzymatic activity assay consequently does not appear to be a reliable detection method for ML-resistance but may be useful for identifying fully susceptible isolates. Taken together, our results point to a reduction in WNV transmission due to the impact of IVM on Culex mosquito populations and support the ongoing investigation of oral administration of IVM to wild birds for local control of WNV transmission, although further work is needed to optimize dosing and understand effects on entomological endpoints.
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Observational data, Journal: Self medication practices and its determinants in health care professionals during the coronavirus disease-2019 pandemic: cross-sectional study. (Pubmed Central) - Apr 19, 2022 Results The mean age of the respondents was 35.6 ± 8.7 years. Two hundred and forty-three respondents (36.3%) reported having practiced COVID-19 related self-medication. The commonly used medications were ivermectin, azithromycin, vitamin C, chloroquine and zinc...Regular health education of the HCPs on implications of self-medications is highly recommended. There should also be formulation and effective implementation of policies that regulate purchase of medications.
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Journal: Unethical studies of ivermectin for covid-19. (Pubmed Central) - Apr 19, 2022 There should also be formulation and effective implementation of policies that regulate purchase of medications. No abstract available
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Journal: Farmers' perception on the control of gastrointestinal parasites in organic and conventional sheep production in Sweden. (Pubmed Central) - Apr 19, 2022 The use of anthelmintics was low (45%), among which a majority (76%) drenched ewes on a single occasion, mostly with ivermectin (59%) followed by albendazole (19%)...In conclusion, although some differences were observed between conventional and organic producers, the divergences were mainly due to herd size categories. Furthermore, despite a high veterinary involvement, we identified factors which can contribute to anthelmintic use, such as poor quarantine procedures, and deworming routines that can contribute to anthelmintic resistance in H. contortus.
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