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Journal: Community Pharmacists' Services during the COVID-19 Pandemic: A Case Study of Lagos State, Nigeria. (Pubmed Central) - Oct 25, 2022 Zinc (98.3%), Vitamin C (97.5%), and ivermectin (95.0%) tablets were the most reported medications for the prevention and treatment of COVID-19 infection. Community pharmacists in Lagos state actively provide pharmacy services and practice various recommended infection prevention and control measures to mitigate the spread of COVID-19 infection in their communities.
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Review, Journal: A Guide to COVID-19 Antiviral Therapeutics: A Summary and Perspective of the Antiviral Weapons Against SARS-CoV-2 Infection. (Pubmed Central) - Oct 22, 2022 Drugs that prevent the virus from replicating include: Paxlovid, remdesivir, molnupiravir, favipiravir, ribavirin, and Kaletra...Lastly, drugs that target immune response regulation include interferons and the use of anti-inflammatory drugs such as dexamethasone...Learning more about these therapies helps raise awareness to the general population about the options available to them to aid in the reduction of the severity of COVID-19 infection. In this 'A Guide To' article, we provide an in-depth insight into the development of antiviral therapeutics against SARS-CoV-2 and their ability to help fight COVID-19.
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Preclinical, Journal: Ivermectin contributes to attenuating the severity of acute lung injury in mice. (Pubmed Central) - Oct 22, 2022 Male C57BL/6 mice were given ivermectin orally every day for the remainder of the experiment at doses of 1 or 2 mg/kg after 24 h of LPS or BLM treatment...These findings suggested that ivermectin may alleviate ALI caused by LPS or BLM in mice, partly via lowering the inflammatory response, which is mediated at least by the inhibition of MAPK and NF-κB signaling. Collectively, ivermectin might be used to treat acute lung injury/acute respiratory distress syndrome.
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