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Clinical, Journal: When Characteristics of Clinical Trials Require Per-Protocol as Well as Intention-to-Treat Outcomes to Draw Reliable Conclusions: Three Examples. (Pubmed Central) - Jun 10, 2023 Inconsistencies and irregularities in the reporting of protocol compliance for this study required consideration of PP outcomes for deaths and hospitalizations, yet the study coauthors refused to disclose them, instead directing inquiring scientists to a data repository which never held the study's data. These three RCTs illustrate conditions under which PP outcomes may differ significantly from ITT outcomes and the need for data transparency when these reported or indicated discrepancies arise.
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Journal: Strongyloides and Eimeria Infection and Its Treatment Way in Sheep. (Pubmed Central) - Jun 9, 2023 and treated with antiparasitic compounds in two forms of tablets (Albendazole, Pyrantel, Ivermectin, Phenasal) and mineral-salt cube (Albenvet, Trimeratinvet)...in sheep (92.18%) (P?0.05). Ant antiparasitic drugs in livestock diet are essential in reducing contamination and its effects on the herd.
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Journal: Against Authority: The Bioethics of Ivermectin Use for COVID-19 Infection. (Pubmed Central) - Jun 8, 2023 N=1000 --> 320 The failures or rather lack of success in decision making during the pandemic showed that alongside scientific knowledge and the development of health policies, it is necessary to constantly evaluate the measures and decisions from an ethical point of view, and the prevention of slippages and abuses is not only necessary but even mandatory.
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Journal: Reply to "oral ivermectin to treat scabies: a comparison of two different regimens". (Pubmed Central) - Jun 8, 2023 The failures or rather lack of success in decision making during the pandemic showed that alongside scientific knowledge and the development of health policies, it is necessary to constantly evaluate the measures and decisions from an ethical point of view, and the prevention of slippages and abuses is not only necessary but even mandatory. No abstract available
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Journal: Ivermectin drug induced liver injury. (Pubmed Central) - Jun 6, 2023 She was managed with low dose corticosteroids, later tapered and withdrawn. She remains well a year after presenting.
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Journal: Can Ivermectin kill Sarcoptes scabiei during the molting process? (Pubmed Central) - Jun 1, 2023 As a consequence, mites may survive after two doses of ivermectin given 7 days apart due not only to hatching eggs but also to the resistance of mites during their molting process. Our results provide insight into the optimal therapeutic regimens for scabies and highlight the need for further research on the molting process of Sarcoptes mites.
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Journal: COVID-19 update: Metformin to prevent long COVID? (Pubmed Central) - May 26, 2023 Thus, this study validates the use of these plants by traditional healers in the management of onchocerciasis and suggests a new source of isolation of the potential plant compounds against Onchocerca. No abstract available
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Preclinical, Journal: Prophylactic administration of ivermectin attenuates SARS-CoV-2 induced disease in a Syrian Hamster Model. (Pubmed Central) - May 15, 2023 Zinc concentrations leading to immune quiescence were also significantly higher in the lungs of ivermectin-treated hamsters compared to controls. These results indicate that ivermectin may have efficacy in reducing the development and severity of COVID-19 by affecting host immunity in a hamster model of SARS-CoV-2 infection.
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