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- | AUTO6NG / Autolus, University College London
Journal, CAR T-Cell Therapy: Detection and quantification of integrated vector copy number by multiplex droplet digital PCR in dual-transduced CAR T (Pubmed Central) - Aug 25, 2023
AUTO6NG is a dual-transduced GD2-targeting CAR that encodes distinct modules designed to enhance T
- AUTO6NG / Autolus
AUTO6NG overcomes immune suppressive mechanisms in the TME and demonstrate preclinical anti-tumor activity in GD2-expressing solid tumors (Virtual Meeting II: E-Posters) - May 16, 2020 - Abstract #AACRII2020AACR-II_1650;
These CAR-T cells also demonstrated enhanced tumor infiltration and anti-tumor activity in vivo in xenografts mouse models. Our findings suggest that GD2 targeted CAR-T cell therapy is a viable novel approach for the treatment of multiple solid tumors indications.