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- fluticasone / Generic mfg.
[VIRTUAL] Non-Localized, Multisegmental and Bilateral Bronchiectasis: Report of Complete Resection of 11 Segments by Bilateral Video-Assisted Thoracic Surgery (VATS) () - Mar 14, 2021 - Abstract #ATS2021ATS_512;
She regularly used fluticasone associated with salmeterol...However, patients with multisegmental and bilateral bronchiectasis, there is still fear of excessive loss of lung function after resection. In the report, the two-phase procedure, starting from the side of greater involvement and preservation of healthy segments, allowed the complete resection of the compromised segments, promoting remission of symptoms, minimal pulmonary loss and greater quality of life.
- hydroxychloroquine / Generic mfg., dexamethasone / Generic mfg.
[VIRTUAL] Effect of Therapeutics on the Modulation of ACE2 Expression in Airway Epithelium: Implications for COVID-19 () - Mar 14, 2021 - Abstract #ATS2021ATS_429;
This affect susceptibility for COVID19 infection and severity of illness in vulnerable populations. Hence basic understanding of mechanism of action for daily standard of care prophylactic therapies can reduce or prevent SAR-CoV-2 infection in at-risk individuals.
- fluticasone / Generic mfg.
[VIRTUAL] Violence-Related Chronic Stress and Asthma Outcomes in the Vitamin D Kids Asthma Study (VDKA) () - Mar 14, 2021 - Abstract #ATS2021ATS_304;
Before randomization, all participants completed a four-week run-in period in which they had to demonstrate ≥75% adherence with the prescribed low-dose ICS (Fluticasone MDI), which was continued throughout the trial... Our findings suggest potentially detrimental effects of ETV-related stress on lung function, asthma control, and asthma-related quality of life in children being treated with ICS in the course of a rigorous clinical trial.
- prednisone / Generic mfg., fluticasone / Generic mfg.
[VIRTUAL] A Continuous Cough After COVID-19 () - Mar 14, 2021 - Abstract #ATS2021ATS_295;
At the end of July, after two months of chronic cough, CT imaging of the chest was performed. CT imaging showed a pattern of lung disease consistent with organizing pneumonia
- | Breo Ellipta (fluticasone furoate / vilanterol) / GSK, Innoviva
New P4 trial: Effect of Fluticasone Furoate/Vilanterol on EIA in Adolescents (clinicaltrials.gov) - Feb 10, 2021
P4, N=92, Completed, Sponsor: Rambam Health Care Campus
- | Alvesco (ciclesonide) / Covis Pharma, Teijin, Korea University Medical Center
Trial completion date, Trial primary completion date: Periostin-guided Withdrawal of Inhaled Corticosteroids in Patients With Non-eosinophilic Asthma (clinicaltrials.gov) - Aug 8, 2020
P=N/A, N=110, Not yet recruiting, Sponsor: Hvidovre University Hospital
CT imaging showed a pattern of lung disease consistent with organizing pneumonia Trial completion date: Dec 2021 --> Dec 2023 | Trial primary completion date: Jun 2021 --> Jun 2023
- | vilanterol (GW642444H) / GSK, Breo Ellipta (fluticasone furoate / vilanterol) / GSK, Innoviva
Trial initiation date, Head-to-Head: Fluticasone-Vilanterol Once Daily Dose for the Treatment of Mild Asthma in Adults (clinicaltrials.gov) - Aug 7, 2020
P2/3, N=130, Not yet recruiting, Sponsor: Royal College of Surgeons in Ireland - Medical University of Bahrain
Trial completion date: Dec 2021 --> Dec 2023 | Trial primary completion date: Jun 2021 --> Jun 2023 Initiation date: Jun 2020 --> Sep 2020
- | Flutiform (fluticasone/formoterol) / Kyorin, Mundipharma, Vectura, Sanofi
Enrollment change, Trial withdrawal: Efficiency Control of Fluticasone/Formoterol K-haler (Medium Strength) vs ICS/LABA (High Strength) in Asthma Patients (clinicaltrials.gov) - Jul 7, 2020
P4, N=0, Withdrawn, Sponsor: Mundipharma Pharmaceuticals S.L.
Initiation date: Jun 2020 --> Sep 2020 N=208 --> 0 | Not yet recruiting --> Withdrawn
- | fluticasone / Generic mfg.
Enrollment change: Effects of Broccoli Sprout Extract on Allergy Rhinitis (clinicaltrials.gov) - Jun 19, 2020
P2, N=47, Completed, Sponsor: VA Office of Research and Development
N=208 --> 0 | Not yet recruiting --> Withdrawn N=75 --> 47
- ||||| Flutiform (fluticasone/formoterol) / Kyorin, Mundipharma, Vectura, Sanofi
New P4 trial: Efficiency Control of Fluticasone/Formoterol K-haler (Medium Strength) vs ICS/LABA (High Strength) in Asthma Patients (clinicaltrials.gov) - Feb 17, 2020
P4, N=208, Not yet recruiting, Sponsor: Mundipharma Pharmaceuticals S.L.
- | vilanterol (GW642444H) / GSK, Breo Ellipta (fluticasone furoate / vilanterol) / GSK, Innoviva
New P2/3 trial, Head-to-Head: Fluticasone-Vilanterol Once Daily Dose for the Treatment of Mild Asthma in Adults (clinicaltrials.gov) - Feb 10, 2020
P2/3, N=130, Not yet recruiting, Sponsor: Royal College of Surgeons in Ireland - Medical University of Bahrain
- | fluticasone / Generic mfg.
Phase classification, Enrollment change: InFLOWt: Inhaled Fluticasone Effects on Upper Airway Patency in Obstructive Lung Disease (clinicaltrials.gov) - Feb 5, 2020
P4, N=25, Terminated, Sponsor: VA Office of Research and Development
N=75 --> 47 Phase classification: P=N/A --> P4 | N=58 --> 25
- | fluticasone / Generic mfg.
Trial completion, Enrollment change: SPARK: Steroids for Pediatric Apnea Research in Kids (clinicaltrials.gov) - Feb 5, 2020
P3, N=211, Completed, Sponsor: Children's Hospital of Philadelphia
Phase classification: P=N/A --> P4 | N=58 --> 25 Recruiting --> Completed | N=318 --> 211
- ||| fluticasone / Generic mfg.
Preclinical, Enrollment change: Enhancement of in−Vitro GC Function in Patients With COPD (clinicaltrials.gov) - Dec 4, 2019
P2, N=49, Completed, Sponsor: Imperial College London
Recruiting --> Completed | N=318 --> 211 N=31 --> 49
- | fluticasone / Generic mfg.
Trial completion, Enrollment change, Trial completion date: Effects of Broccoli Sprout Extract on Allergy Rhinitis (clinicaltrials.gov) - Nov 12, 2019
P2, N=75, Completed, Sponsor: VA Office of Research and Development
N=31 --> 49 Active, not recruiting --> Completed | N=475 --> 75 | Trial completion date: Oct 2019 --> Mar 2019
- | montelukast / Generic mfg., fluticasone / Generic mfg.
Enrollment change, Trial withdrawal: Eosinophilic Esophagitis Treatment: Montelukast vs Fluticasone (clinicaltrials.gov) - Aug 28, 2019
P3, N=0, Withdrawn, Sponsor: Medical College of Wisconsin
Active, not recruiting --> Completed | N=475 --> 75 | Trial completion date: Oct 2019 --> Mar 2019 N=100 --> 0 | Active, not recruiting --> Withdrawn
- | fluticasone / Generic mfg.
Trial completion date, Trial primary completion date: SPARK: Steroids for Pediatric Apnea Research in Kids (clinicaltrials.gov) - Jul 8, 2019
P3, N=318, Recruiting, Sponsor: Children's Hospital of Philadelphia
N=100 --> 0 | Active, not recruiting --> Withdrawn Trial completion date: Jun 2019 --> Dec 2019 | Trial primary completion date: Jun 2019 --> Dec 2019
- | Flutiform (fluticasone/formoterol) / Kyorin, Mundipharma, Vectura, Sanofi
Biomarker, New P4 trial: An Open Label Oxygen Enhanced Imaging Biomarker Study in Moderate to Severe Asthma. (EUDRACT) - Jun 18, 2019
P4, N=17, Completed, Sponsor: The University of Leicester
- | fluticasone / Generic mfg.
Trial completion: Budesonide Versus Fluticasone for Treatment of Eosinophilic Esophagitis (clinicaltrials.gov) - May 15, 2019
P4, N=129, Completed, Sponsor: University of North Carolina, Chapel Hill
Trial completion date: Jun 2019 --> Dec 2019 | Trial primary completion date: Jun 2019 --> Dec 2019 Active, not recruiting --> Completed
- | fluticasone / Generic mfg.
Enrollment closed, Trial primary completion date: Effects of Broccoli Sprout Extract on Allergy Rhinitis (clinicaltrials.gov) - Mar 20, 2019
P2, N=475, Active, not recruiting, Sponsor: VA Office of Research and Development
Active, not recruiting --> Completed Recruiting --> Active, not recruiting | Trial primary completion date: Oct 2019 --> Mar 2019
- | Alvesco (ciclesonide) / Covis Pharma, Teijin, Korea University Medical Center
Trial completion date, Trial initiation date, Trial primary completion date: Periostin-guided Withdrawal of Inhaled Corticosteroids in Patients With Non-eosinophilic Asthma (clinicaltrials.gov) - Feb 25, 2019
P=N/A, N=110, Not yet recruiting, Sponsor: Hvidovre University Hospital
Recruiting --> Active, not recruiting | Trial primary completion date: Oct 2019 --> Mar 2019 Trial completion date: Dec 2020 --> Dec 2021 | Initiation date: Jan 2019 --> Sep 2019 | Trial primary completion date: Jun 2020 --> Jun 2021
- | omeprazole / Generic mfg., fluticasone / Generic mfg.
New P4 trial: EoE RCT Fluticasone and Omeprazole vs Fluticasone Alone (clinicaltrials.gov) - Dec 20, 2018
P4, N=100, Recruiting, Sponsor: Claire Daniels
- | Flutiform (fluticasone/formoterol) / Kyorin, Mundipharma, Vectura, Sanofi
Enrollment change, Trial completion date, Trial withdrawal, Trial primary completion date, Adherence: Flutiform in Treatment of Patients With Asthma in Daily Clinical Practice. (clinicaltrials.gov) - Nov 16, 2018
P=N/A, N=0, Withdrawn, Sponsor: Mundipharma Pharmaceuticals B.V.
Trial completion date: Dec 2020 --> Dec 2021 | Initiation date: Jan 2019 --> Sep 2019 | Trial primary completion date: Jun 2020 --> Jun 2021 N=250 --> 0 | Trial completion date: Nov 2018 --> Dec 2016 | Not yet recruiting --> Withdrawn | Trial primary completion date: Mar 2018 --> Dec 2016
- | azelastine intranasal / Generic mfg., fluticasone / Generic mfg.
Enrollment change, Trial completion date, Trial termination, Trial primary completion date: MAN06: Effects of Intranasal Fluticasone Plus Azelastine on Airway Inflammation in Patients With Asthma & Allergic Rhinitis (clinicaltrials.gov) - Oct 31, 2018
P4, N=7, Terminated, Sponsor: University of Dundee
N=250 --> 0 | Trial completion date: Nov 2018 --> Dec 2016 | Not yet recruiting --> Withdrawn | Trial primary completion date: Mar 2018 --> Dec 2016 N=20 --> 7 | Trial completion date: Jun 2019 --> Sep 2018 | Recruiting --> Terminated | Trial primary completion date: Jun 2019 --> Sep 2018; The company providing study IMP was unable to supply further batches of IMP.
- | fluticasone / Generic mfg.
Trial completion, Heterogeneity: EXPAND: Effect of Extra- Fine Versus Coarse-Particle Inhaled Corticosteroids (ICS) on Ventilation Heterogeneity in Children With Poorly Controlled Asthma (clinicaltrials.gov) - Oct 25, 2018
P4, N=31, Completed, Sponsor: University of Virginia
N=20 --> 7 | Trial completion date: Jun 2019 --> Sep 2018 | Recruiting --> Terminated | Trial primary completion date: Jun 2019 --> Sep 2018; The company providing study IMP was unable to supply further batches of IMP. Enrolling by invitation --> Completed
- | fluticasone / Generic mfg.
Trial completion date, Trial primary completion date: SPARK: Steroids for Pediatric Apnea Research in Kids (clinicaltrials.gov) - Sep 14, 2018
P3, N=318, Recruiting, Sponsor: Children's Hospital of Philadelphia
Enrolling by invitation --> Completed Trial completion date: Jun 2018 --> Jun 2019 | Trial primary completion date: Jun 2018 --> Jun 2019
- | Alvesco (ciclesonide) / Covis Pharma, Teijin, Korea University Medical Center
Trial completion date, Trial initiation date, Trial primary completion date: Periostin-guided Withdrawal of Inhaled Corticosteroids in Patients With Non-eosinophilic Asthma (clinicaltrials.gov) - Aug 21, 2018
P=N/A, N=110, Not yet recruiting, Sponsor: Hvidovre University Hospital
Trial completion date: Jun 2018 --> Jun 2019 | Trial primary completion date: Jun 2018 --> Jun 2019 Trial completion date: Dec 2019 --> Dec 2020 | Trial primary completion date: Dec 2019 --> Jun 2020 | Initiation date: Jun 2018 --> Jan 2019
- | fluticasone / Generic mfg.
Trial termination: Inhaled Steroids at Discharge After Emergency Department Visits for Children With Uncontrolled Asthma (clinicaltrials.gov) - Apr 11, 2018
P=N/A, N=118, Terminated, Sponsor: Rhode Island Hospital
Trial completion date: Dec 2019 --> Dec 2020 | Trial primary completion date: Dec 2019 --> Jun 2020 | Initiation date: Jun 2018 --> Jan 2019 Recruiting --> Terminated; Funding complete
- | fluticasone / Generic mfg.
Enrollment closed, Trial completion date: Budesonide Versus Fluticasone for Treatment of Eosinophilic Esophagitis (clinicaltrials.gov) - Mar 22, 2018
P4, N=173, Active, not recruiting, Sponsor: University of North Carolina, Chapel Hill
Recruiting --> Terminated; Funding complete Recruiting --> Active, not recruiting | Trial completion date: Jul 2018 --> May 2019
- | azelastine intranasal / Generic mfg., fluticasone / Generic mfg.
Enrollment open, Trial completion date, Trial primary completion date: MAN06: Effects of Intranasal Fluticasone Plus Azelastine on Airway Inflammation in Patients With Asthma & Allergic Rhinitis (clinicaltrials.gov) - Mar 20, 2018
P4, N=20, Recruiting, Sponsor: University of Dundee
Recruiting --> Active, not recruiting | Trial completion date: Jul 2018 --> May 2019 Not yet recruiting --> Recruiting | Trial completion date: Dec 2018 --> Jun 2019 | Trial primary completion date: Dec 2018 --> Jun 2019
- | Alvesco (ciclesonide) / Covis Pharma, Teijin, Korea University Medical Center
Trial completion date, Trial initiation date, Trial primary completion date: Periostin-guided Withdrawal of Inhaled Corticosteroids in Patients With Non-eosinophilic Asthma (clinicaltrials.gov) - Mar 5, 2018
P=N/A, N=110, Not yet recruiting, Sponsor: Hvidovre University Hospital
Not yet recruiting --> Recruiting | Trial completion date: Dec 2018 --> Jun 2019 | Trial primary completion date: Dec 2018 --> Jun 2019 Trial completion date: Sep 2019 --> Dec 2019 | Initiation date: Sep 2017 --> Jun 2018 | Trial primary completion date: Sep 2019 --> Dec 2019
- | fluticasone / Generic mfg.
New P3 trial: Effects of the Direct Interaction Between Streptococcus Salivarius 24SMBc and Streptococcus Oralis 89a and the Respiratory Epithelium in Children (clinicaltrials.gov) - Mar 1, 2018
P3, N=60, Not yet recruiting, Sponsor: Federico II University
- | prednisolone / Generic mfg., fluticasone / Generic mfg.
Trial termination: Management of Recurrent Croup (clinicaltrials.gov) - Nov 13, 2017
P3, N=10, Terminated, Sponsor: University of Michigan
Trial completion date: Sep 2019 --> Dec 2019 | Initiation date: Sep 2017 --> Jun 2018 | Trial primary completion date: Sep 2019 --> Dec 2019 Completed --> Terminated
- |||||||||| triamcinolone acetonide / Generic mfg., fluticasone / Generic mfg.
New P3 trial, Head-to-Head: NASANIF: A Study to Assess Efficacy and Safety of Nasacort® Nasal Spray in Comparison With Flixonase® Nasal Spray in Adults Suffering From Perennial Allergic Rhinitis (PAR) (clinicaltrials.gov) - Oct 23, 2017
P3, N=260, Completed, Sponsor: Sanofi
- | fluticasone / Generic mfg.
Phase classification: Budesonide Versus Fluticasone for Treatment of Eosinophilic Esophagitis (clinicaltrials.gov) - Oct 19, 2017
P4, N=200, Recruiting, Sponsor: University of North Carolina, Chapel Hill
Completed --> Terminated Phase classification: P=N/A --> P4
- ||||||| Flutiform (fluticasone/formoterol) / Kyorin, Mundipharma, Vectura, Sanofi
Trial completion, Heterogeneity: A Study to Evaluate the Effect of Fluticasone/Formoterol Breath Actuated Inhaler (BAI) or Relvar (clinicaltrials.gov) - Aug 22, 2017
P3, N=105, Completed, Sponsor: Mundipharma Research Limited
Phase classification: P=N/A --> P4 Active, not recruiting --> Completed
- | fluticasone / Generic mfg.
Trial completion: STICS: Step-up Yellow Zone Inhaled Corticosteroids to Prevent Exacerbations (clinicaltrials.gov) - Jul 27, 2017
P3, N=254, Completed, Sponsor: Milton S. Hershey Medical Center
Active, not recruiting --> Completed Active, not recruiting --> Completed
- ||||| Flutiform (fluticasone/formoterol) / Kyorin, Mundipharma, Vectura, Sanofi
Enrollment closed, Heterogeneity: A Study to Evaluate the Effect of Fluticasone/Formoterol Breath Actuated Inhaler (BAI) or Relvar (clinicaltrials.gov) - Jul 19, 2017
P3, N=105, Active, not recruiting, Sponsor: Mundipharma Research Limited
Active, not recruiting --> Completed Recruiting --> Active, not recruiting
- | fluticasone / Generic mfg.
New trial: Radiologic Scoring of Patients With Chronic Sinusitis and Nasal Polyps (clinicaltrials.gov) - Jun 2, 2017
P=N/A, N=60, Recruiting, Sponsor: Assiut University
- | fluticasone / Generic mfg.
Enrollment change: Budesonide Versus Fluticasone for Treatment of Eosinophilic Esophagitis (clinicaltrials.gov) - May 17, 2017
P=N/A, N=200, Recruiting, Sponsor: University of North Carolina, Chapel Hill
Recruiting --> Active, not recruiting N=122 --> 200
- | fluticasone / Generic mfg.
Enrollment change, Trial withdrawal: ReHICS: Repeated High-dose Inhaled Corticosteroids for Asthma (clinicaltrials.gov) - May 16, 2017
P2, N=0, Withdrawn, Sponsor: Johns Hopkins University
N=122 --> 200 N=20 --> 0 | Completed --> Withdrawn
- | fluticasone / Generic mfg.
Enrollment status, Trial initiation date, Trial primary completion date, Heterogeneity: EXPAND: Effect of Extra- Fine Versus Coarse-Particle Inhaled Corticosteroids (ICS) on Ventilation Heterogeneity in Children With Poorly Controlled Asthma (clinicaltrials.gov) - May 10, 2017
P4, N=30, Enrolling by invitation, Sponsor: University of Virginia
N=20 --> 0 | Completed --> Withdrawn Recruiting --> Enrolling by invitation | Initiation date: Mar 2016 --> Jun 2016 | Trial primary completion date: Nov 2017 --> Jun 2018
- | Alvesco (ciclesonide) / Covis Pharma, Teijin, Korea University Medical Center
New trial: Periostin-guided Withdrawal of Inhaled Corticosteroids in Patients With Non-eosinophilic Asthma (clinicaltrials.gov) - May 5, 2017
P=N/A, N=110, Not yet recruiting, Sponsor: Hvidovre University Hospital
- | montelukast / Generic mfg., azithromycin / Generic mfg., fluticasone / Generic mfg.
New trial: Early Detection and Management of Bronchiolitis Obliterans Syndrome Following Pediatric Hematopoietic Stem Cell Transplantation (clinicaltrials.gov) - Mar 7, 2017
P=N/A, N=40, Recruiting, Sponsor: Ann & Robert H Lurie Children's Hospital of Chicago
- fluticasone / Generic mfg.
Enrollment open: Effects of Broccoli Sprout Extract on Allergy Rhinitis (clinicaltrials.gov) - Feb 9, 2017
P2, N=475, Recruiting, Sponsor: VA Office of Research and Development
Recruiting --> Enrolling by invitation | Initiation date: Mar 2016 --> Jun 2016 | Trial primary completion date: Nov 2017 --> Jun 2018 Not yet recruiting --> Recruiting
- Flutiform (fluticasone/formoterol) / Kyorin, Mundipharma, Vectura, Sanofi
Enrollment change, Trial termination, Trial primary completion date: A Study to Compare Fluticasone /Formoterol Breath Actuated Inhaler (BAI) and Ultibro in Subjects With Fixed Airflow Obstruction and Elevated Eosinophils (clinicaltrials.gov) - Dec 12, 2016
P2/3, N=2, Terminated, Sponsor: Mundipharma Research Limited
Not yet recruiting --> Recruiting N=130 --> 2 | Recruiting --> Terminated | Trial primary completion date: Sep 2017 --> Oct 2016; Recruitment issues
- | azelastine intranasal / Generic mfg., fluticasone / Generic mfg.
New P4 trial: MAN06: Effects of Intranasal Fluticasone Plus Azelastine on Airway Inflammation in Patients With Asthma & Allergic Rhinitis (clinicaltrials.gov) - Nov 2, 2016
P4, N=20, Not yet recruiting, Sponsor: University of Dundee
- fluticasone / Generic mfg.
Trial primary completion date: Inhaled Steroids at Discharge After Emergency Department Visits for Children With Uncontrolled Asthma (clinicaltrials.gov) - Oct 11, 2016
P=N/A, N=143, Recruiting, Sponsor: Rhode Island Hospital
N=130 --> 2 | Recruiting --> Terminated | Trial primary completion date: Sep 2017 --> Oct 2016; Recruitment issues Trial primary completion date: Jul 2016 --> Dec 2017
- fluticasone / Generic mfg.
Trial termination: Does Inhaled Busedonide or Fluticasone Impair Adrenal Function? (clinicaltrials.gov) - Sep 8, 2016
P=N/A, N=50, Terminated, Sponsor: HaEmek Medical Center, Israel
Trial primary completion date: Jul 2016 --> Dec 2017 Recruiting --> Terminated; recruiting subjects did not start.
- | fluticasone / Generic mfg.
New P2 trial: Effects of Broccoli Sprout Extract on Allergy Rhinitis (clinicaltrials.gov) - Aug 31, 2016
P2, N=475, Not yet recruiting, Sponsor: VA Office of Research and Development