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Trial + Data / Events	Status	Ph	N	Region	Interventions	Sponsor	Conditions	Primary compl	Study compl
MK-8527 / Merck (MSD)
NCT06045507: Safety and Pharmacokinetic Study of Oral MK-8527 QM in Participants at Low-Risk for HIV-1 Infection (MK-8527-007)	Active, not recruiting	2	350	US, RoW	MK-8527, Placebo to MK-8527	Merck Sharp & Dohme LLC	HIV, HIV Pre-exposure Prophylaxis	12/24	12/24
MK-8527-004, NCT05494736: MK-8527 Single-Dose Trial in HIV-1 Infected Participants	Completed	1	20	Europe, RoW	MK-8527	Merck Sharp & Dohme LLC	Human Immunodeficiency Virus	01/24	01/24
MK-8527-008, NCT06295796: A Study of MK-8527 in Participants With Moderate and Severe Renal Impairment	Recruiting	1	18	US	MK-8527	Merck Sharp & Dohme LLC	Renal Impairment	04/25	04/25