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Trial + Data / Events	Status	Ph	N	Region	Interventions	Sponsor	Conditions	Primary compl	Study compl
KB105 / Krystal Biotech
NCT05735158: Topical KB105 for the Treatment of TGM1-deficient Autosomal Recessive Congenital Ichthyosis (ARCI)	Not yet recruiting	2	15	US	KB105, Placebo	Krystal Biotech, Inc.	Autosomal Recessive Ichthyosis	03/24	04/24
NCT04047732: Topical KB105 Gene Therapy for the Treatment of TGM1-deficient Autosomal Recessive Congenital Ichthyosis (ARCI)	Active, not recruiting	1/2	6	US	KB105, HSV1-TGM1	Krystal Biotech, Inc.	TGM-1 Related Autosomal Recessive Congenital Ichthyosis	10/22	03/25