lemzoparlimab (ABBV-IMAB-TJC4) / I-Mab 
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5 Trials

   

Trial + Data / EventsStatusPhNRegionInterventionsSponsorConditionsPrimary complStudy compl
lemzoparlimab (ABBV-IMAB-TJC4) / I-Mab
NCT05709093: A Phase 3 Clinical Study to Evaluate Lemzoparlimab for Injection in Combination With Azacitidine (AZA) Versus AZA Monotherapy in Treatment-naïve Patients With Higher-risk Myelodysplastic Syndrome (MDS)

Recruiting
3
552
RoW
Lemzoparlimab+Azacitidine (AZA), Azacitidine (AZA)
TJ Biopharma Co., Ltd.
Myelodysplastic Syndromes(MDS)
03/27
03/27
NCT05148533: A Study of Single Drug TJ011133 and Toripalimab Combine Treatment for Advanced Solid Tumor

Terminated
1/2
7
RoW
TJ1133 Injection
TJ Biopharma Co., Ltd.
Advanced Solid Tumor
02/23
02/23
NCT04202003: A Study to Evaluate the Safety and Tolerability, Pharmacokinetics, Pharmacodynamics and Preliminary Efficacy of TJ011133 as Monotherapy and in Combination With Azacitidine (AZA) in Patients With Acute Myeloid Leukemia (AML) or Myelodysplastic Syndrome (MDS)

Checkmark Efficacy data from trial in combination with azacitidine for MDS
Sep 2022 - Sep 2022: Efficacy data from trial in combination with azacitidine for MDS
Checkmark Data from a study in combination with azacitidine for MDS at ESMO 2022
Sep 2022 - Sep 2022: Data from a study in combination with azacitidine for MDS at ESMO 2022
Completed
1/2
105
RoW
TJ011133
TJ Biopharma Co., Ltd.
Acute Myeloid Leukemia (AML), Myelodysplastic Syndromes(MDS)
12/23
12/23
KEYNOTE-A21, NCT03934814: Study of TJ011133 in Participants With Relapsed/Refractory Advanced Solid Tumors and Lymphoma

Completed
1
98
US, RoW
TJ011133, Pembrolizumab, KEYTRUDA®, Rituximab, Rituxan, MabThera
I-Mab Biopharma US Limited, Merck Sharp & Dohme LLC
Solid Tumor, Lymphoma
01/23
01/23
NCT04912063: Study to Evaluate Adverse Events and Movement of Lemzoparlimab in Body When Used Intravenously (IV) With Azacitidine Subcutaneously or IV and Venetoclax Orally in Participants With Acute Myeloid Leukemia and With Azacitidine With or Without Venetoclax in Participants With Myelodysplastic Syndrome

Terminated
1
40
Europe, Japan, US, RoW
Lemzoparlimab, TJ011133, ABBV-IMAB-TJC4, Azacitidine, Venetoclax, Venclexta, Venclyxto, ABT-199, GDC-0199
AbbVie
Acute Myeloid Leukemia (AML), Myelodysplastic Syndrome (MDS)
05/23
05/23

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