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Trial + Data / Events	Status	Ph	N	Region	Interventions	Sponsor	Conditions	Primary compl	Study compl
UB-421 IV / United BioPharma
NCT03149211: To Investigate the Efficacy and Safety of UB-421 Monotherapy in HIV-1 Infected Adults	Withdrawn	3	520	RoW	UB-421, dB4C7 mAb, current standard HAART treatment	United BioPharma	HIV-1 Infection	12/25	12/25
NCT04406727: UB-421 in Combination With Optimized Background Regimen in Patients With Multi-drug Resistant HIV-1 Infection	Not yet recruiting	3	50	NA	UB-421, Antiretroviral (ARV)	United BioPharma	HIV-1 Infection	06/26	06/26
NCT05056974: A Proof-of-concept Trial to Evaluate the Safety and Efficacy of UB-421 Plus Chidamide in Changing HIV Reservoirs	Completed	2	11	RoW	UB-421, chidamide	United BioPharma	HIV-1 Infection	02/23	02/23
NCT03164447: UB-421 Combine With Optimized Background Therapy Regimen in Multi-Drug Resistant HIV-1 Infection Patients	Not yet recruiting	2	10	NA	UB-421, Optimized background therapy (OBT)	United BioPharma	HIV-1 Infection	03/24	05/24
NCT04404049: The HIV Functional Cure Potential of UB-421 in ART Stabilized HIV-1 Patients	Not yet recruiting	2	39	NA	UB-421(25 mg/kg) Q2W, UB-421(25 mg/kg) Q4W	UBP Greater China (Shanghai) Co., Ltd	HIV-1-infection	06/24	06/25
NCT05582694: A Trial of Anti-CD4 Antibody UB-421 in Combination With Optimized Background Antiretroviral Therapy in Patients With Multi-Drug Resistant HIV-1 Infection	Recruiting	2	25	US	UB-421	National Institute of Allergy and Infectious Diseases (NIAID)	Multi-Drug Resistant Hiv-1 Infection, HIV-1 Infection	12/25	12/25
NCT04985890: A Proof of Concept Study to Evaluate the Effect of UB-421 in Combination With Chidamide on HIV Viral Reservoir	Not yet recruiting	2	20	NA	UB-421, UB-421+chidamide	UBP Greater China (Shanghai) Co., Ltd	HIV-1-infection	12/26	12/27