LAI287/semaglutide (NN1535) / Novo Nordisk 
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8 Trials

   

 
Trial + Data / EventsStatusPhNRegionInterventionsSponsorConditionsPrimary complStudy compl
LAI287/semaglutide (NN1535) / Novo Nordisk
2020-005309-18: A research study to see how well the new weekly medicine IcoSema, which is a combination of insulin icodec and semaglutide, controls blood sugar level in people with type 2 diabetes compared to insulin glargine taken daily with insulin aspart (COMBINE 3) Klinikai vizsgálat annak tanulmányozására, hogy az IcoSema, az ikodek inzulin és a szemaglutid kombinációjából álló, hetente alkalmazott új gyógyszer mennyire kontrollálja jól a 2-es típusú cukorbetegek vércukorszintjét a naponta, aszpart inzulinnal együtt alkalmazott glargin inzulinnal összehasonlítva (COMBINE 3)

Ongoing
3
680
Europe
IcoSema 700 U/mL + 2 mg/mL PDS290, Solution for injection in pre-filled pen, Solution for injection, Lantus SoloStar, NovoRapid FlexPen
Novo Nordisk A/S, Novo Nordisk A/S
Diabetes Mellitus, Type 2 2-es típusú diabétesz mellitus, Type 2 diabetes, Diseases [C] - Nutritional and Metabolic Diseases [C18]
 
 
2020-005281-34: A research study to see how well the new weekly medicine IcoSema, which is a combination of insulin icodec and semaglutide, controls blood sugar level in people with type 2 diabetes compared to weekly insulin icodec (COMBINE 1)

Ongoing
3
1290
Europe, RoW
IcoSema 700 U/ml + 2 mg/mL PDS290, insulin icodec 700 U/mL PDS290, Solution for injection in pre-filled pen, Solution for injection
Novo Nordisk A/S, Novo Nordisk A/S
Diabetes Mellitus, Type 2, Type 2 diabetes, Diseases [C] - Nutritional and Metabolic Diseases [C18]
 
 
2020-005308-21: A research study to see how well the new weekly medicine IcoSema, which is a combination of insulin icodec and semaglutide, controls blood sugar level in people with type 2 diabetes compared to weekly semaglutide (COMBINE 2) COMBINE 2 – Klinické skúšanie, ktoré skúma ako dobre nový liek IcoSema, ktorý je kombináciou inzulínu icodec a semaglutidu, kontroluje hladinu cukru v krvi u ľudí s cukrovkou 2. typu, a porovnáva ho s liekom semaglutid, oba podávané raz týždenne

Ongoing
3
680
Europe
IcoSema 700 U/ml + 2 mg/mL PDS290, Solution for injection, Solution for injection in pre-filled pen, Ozempic
Novo Nordisk A/S, Novo Nordisk A/S
Diabetes Mellitus, Type 2, Type 2 diabetes, Diseases [C] - Nutritional and Metabolic Diseases [C18]
 
 
COMBINE 3, NCT05013229 / 2020-005309-18: A Research Study to See How Well the New Weekly Medicine IcoSema, Which is a Combination of Insulin Icodec and Semaglutide, Controls Blood Sugar Level in People With Type 2 Diabetes Compared to Insulin Glargine Taken Daily With Insulin Aspart

Completed
3
679
Europe, Japan, US, RoW
IcoSema, Insulin glargine, insulin aspart
Novo Nordisk A/S, Novo Nordisk A/S
Diabetes Mellitus, Type 2
11/23
11/23
COMBINE 2, NCT05259033 / 2020-005308-21: A Research Study to See How Well the New Weekly Medicine IcoSema, Which is a Combination of Insulin Icodec and Semaglutide, Controls Blood Sugar Level in People With Type 2 Diabetes Compared to Weekly Semaglutide

Completed
3
683
Europe, Canada, Japan, US, RoW
IcoSema, Semaglutide 1 mg
Novo Nordisk A/S, Novo Nordisk A/S
Diabetes Mellitus, Type 2
12/23
01/24
COMBINE 4, NCT06269107: A Research Study to See How Well New Weekly Medicine IcoSema, Which is a Combination of Insulin Icodec and Semaglutide, Controls Blood Sugar Levels in People With Type 2 Diabetes (T2D), Compared to Daily Insulin Glargine

Active, not recruiting
3
474
Europe, Japan, US, RoW
IcoSema, Insulin glargine
Novo Nordisk A/S
Type 2 Diabetes
05/25
06/25
COMBINE 1, NCT05352815 / 2020-005281-34: A Research Study to See How Well the New Weekly Medicine IcoSema, Which is a Combination of Insulin Icodec and Semaglutide, Controls Blood Sugar Level in People With Type 2 Diabetes Compared to Weekly Insulin Icodec

Completed
3
1291
Europe, Japan, US, RoW
IcoSema, Insulin icodec
Novo Nordisk A/S, Novo Nordisk A/S
Diabetes Mellitus, Type 2
03/24
04/24
NCT05435677: A Research Study to Look at How Insulin Icodec and Semaglutide Work in the Body of People From China With Type 2 Diabetes When Given Alone or Together

Completed
1
20
RoW
IcoSema, insulin icodec, semaglutide
Novo Nordisk A/S
Diabetes Mellitus, Type 2
04/23
04/23

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