lerapolturev (PVS-RIPO) / Istari Oncology 
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8 Trials

   

 
Trial + Data / EventsStatusPhNRegionInterventionsSponsorConditionsPrimary complStudy compl
lerapolturev (PVS-RIPO) / Istari Oncology
LUMINOS-102, NCT04577807: Lerapolturev With or Without Immune Checkpoint Blockade in Advanced PD-1 Refractory Melanoma

Active, not recruiting
2
56
US
Lerapolturev, Anti-PD-1 Checkpoint Inhibitor
Istari Oncology, Inc.
Melanoma
10/24
12/24
NCT02986178: PVSRIPO in Recurrent Malignant Glioma

Active, not recruiting
2
122
US
PVSRIPO
Istari Oncology, Inc., Duke University
Malignant Glioma
03/24
03/24
LUMINOS-101, NCT04479241: Lerapolturev (PVSRIPO) and Pembrolizumab in Patients with Recurrent Glioblastoma

Completed
2
25
US
lerapolturev, pembrolizumab
Istari Oncology, Inc.
Glioblastoma, Recurrent Glioblastoma, Supratentorial Glioblastoma, Brain Tumor
06/24
06/24
NCT06177964: Lerapolturev (PVSRIPO) in GBM

Recruiting
2
92
US
Lerapolturev, Lomustine Pill
Darell Bigner, Istari Oncology, Inc.
Recurrent Supratentorial Glioblastoma
02/29
02/29
LUMINOS-103, NCT04690699: A Basket Trial of Safety & Efficacy of Lerapolturev With or Without Checkpoint Inhibitors

Terminated
1/2
4
US
Lerapolturev, 5% DDM
Istari Oncology, Inc.
Solid Tumor, Bladder Cancer, Non-muscle-invasive Bladder Cancer
04/24
06/24
NCT03043391: Phase 1b Study PVSRIPO for Recurrent Malignant Glioma in Children

Completed
1
8
US
Polio/Rhinovirus Recombinant (PVSRIPO)
Istari Oncology, Inc., Solving Kids' Cancer, The Andrew McDonough B+ Foundation, Duke University
Malignant Glioma, Anaplastic Astrocytoma, Anaplastic Oligoastrocytoma, Anaplastic Oligodendroglioma, Glioblastoma, Gliosarcoma, Atypical Teratoid/Rhabdoid Tumor of Brain, Medulloblastoma, Ependymoma, Pleomorphic Xanthoastrocytoma of Brain, Embryonal Tumor of Brain
03/22
03/22
NCT03564782: Examining Bioactivity of PVSRIPO in Invasive Breast Cancer

Completed
1
5
US
PVSRIPO
Istari Oncology, Inc., Duke University, United States Department of Defense
Invasive Breast Cancer
04/22
04/22
NCT04599647: EAP for the Treatment of Glioblastoma With PVSRIPO

No Longer Available
N/A
US
PVSRIPO
Istari Oncology, Inc.
Glioblastoma
 
 

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