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- | lithium carbonate ER / Generic mfg.
Enrollment open: Lithium Effects on the Brain's Functional and Structural Connectome in the Treatment of Bipolar Disorder (clinicaltrials.gov) - Dec 13, 2017
P=N/A, N=120, Recruiting, Sponsor: The Cleveland Clinic
Not yet recruiting --> Recruiting
- | lithium carbonate ER / Generic mfg.
Trial completion, Enrollment change, Trial primary completion date: The Neurotrophic Effects of Lithium Carbonate Following Stroke: A Feasibility Study (clinicaltrials.gov) - Oct 26, 2017
P3, N=12, Completed, Sponsor: Sunnybrook Health Sciences Centre
Not yet recruiting --> Recruiting Recruiting --> Completed | N=35 --> 12 | Trial primary completion date: Mar 2018 --> Jul 2017
- | lithium carbonate ER / Generic mfg., ketamine / Generic mfg.
Trial initiation date: Effect of Lithium Versus Placebo in Adults With Treatment-Resistant Depression Who Are Receiving Ketamine (clinicaltrials.gov) - Oct 21, 2017
P2, N=40, Enrolling by invitation, Sponsor: William V. Bobo, M.D.
Recruiting --> Completed | N=35 --> 12 | Trial primary completion date: Mar 2018 --> Jul 2017 Initiation date: Sep 2017 --> Mar 2018
- | lithium carbonate ER / Generic mfg.
Enrollment open, Enrollment change, HEOR: Longitudinal Comparative Effectiveness of Bipolar Disorder Therapies (clinicaltrials.gov) - Oct 13, 2017
P=N/A, N=1300000, Enrolling by invitation, Sponsor: University of New Mexico
Initiation date: Sep 2017 --> Mar 2018 Not yet recruiting --> Enrolling by invitation | N=1000000 --> 1300000
- | lithium carbonate ER / Generic mfg., ketamine / Generic mfg.
Enrollment open: Effect of Lithium Versus Placebo in Adults With Treatment-Resistant Depression Who Are Receiving Ketamine (clinicaltrials.gov) - Sep 26, 2017
P2, N=40, Enrolling by invitation, Sponsor: William V. Bobo, M.D.
Not yet recruiting --> Enrolling by invitation | N=1000000 --> 1300000 Not yet recruiting --> Enrolling by invitation
- | lithium carbonate ER / Generic mfg., ketamine / Generic mfg.
New P2 trial: Effect of Lithium Versus Placebo in Adults With Treatment-Resistant Depression Who Are Receiving Ketamine (clinicaltrials.gov) - Sep 25, 2017
P2, N=40, Not yet recruiting, Sponsor: William V. Bobo, M.D.
- | lithium carbonate ER / Generic mfg.
Enrollment open: LATTICE: Lithium As a Treatment to Prevent Impairment of Cognition in Elders (clinicaltrials.gov) - Sep 11, 2017
P4, N=80, Recruiting, Sponsor: Ariel Gildengers
Not yet recruiting --> Enrolling by invitation Not yet recruiting --> Recruiting
- | lithium carbonate ER / Generic mfg.
Enrollment change, Trial primary completion date: Wake Therapy in the Treatment of Depression (clinicaltrials.gov) - Aug 17, 2017
P=N/A, N=25, Recruiting, Sponsor: New York State Psychiatric Institute
Not yet recruiting --> Recruiting N=10 --> 25 | Trial primary completion date: Jul 2012 --> Aug 2019
- | lithium carbonate ER / Generic mfg.
Trial completion: Prevention of Relapse & Recurrence of Bipolar Depression (clinicaltrials.gov) - Aug 10, 2017
P4, N=184, Completed, Sponsor: University of Pennsylvania
N=10 --> 25 | Trial primary completion date: Jul 2012 --> Aug 2019 Active, not recruiting --> Completed
- | lithium carbonate ER / Generic mfg., olanzapine / Generic mfg.
Enrollment open, Trial primary completion date: Olanzapine Versus Lithium in the Treatment of Acute Depression in Patients With Bipolar II or Bipolar Not Otherwise Specified(OL Study) (clinicaltrials.gov) - Jul 21, 2017
P4, N=236, Recruiting, Sponsor: Tadashi Hasegawa
Active, not recruiting --> Completed Not yet recruiting --> Recruiting | Trial primary completion date: Aug 2016 --> Oct 2019
- ||||| New P4 trial: SALT Study (Switching to the Administration of Lithium Slow -Release Treatment) (clinicaltrials.gov) - Jul 7, 2017
P4, N=138, Recruiting, Sponsor: Aziende Chimiche Riunite Angelini Francesco S.p.A
- | lithium carbonate ER / Generic mfg.
New P1/2 trial: Study of Lithium Carbonate to Treat Niemann-Pick Type C1 Disease (clinicaltrials.gov) - Jun 27, 2017
P1/2, N=7, Recruiting, Sponsor: Xinhua Hospital, Shanghai Jiao Tong University School of Medicine
- | lithium carbonate ER / Generic mfg.
New P4 trial: LATTICE: Lithium As a Treatment to Prevent Impairment of Cognition in Elders (clinicaltrials.gov) - Jun 14, 2017
P4, N=80, Not yet recruiting, Sponsor: Ariel Gildengers
- | lithium carbonate ER / Generic mfg.
Trial completion: Neuroprotective Effects of Lithium in Patients With Small Cell Lung Cancer Undergoing Radiation Therapy to the Brain (clinicaltrials.gov) - Jun 9, 2017
P1/2, N=19, Completed, Sponsor: Washington University School of Medicine
Not yet recruiting --> Recruiting | Trial primary completion date: Aug 2016 --> Oct 2019 Active, not recruiting --> Completed
- | lithium carbonate ER / Generic mfg.
Enrollment closed, Enrollment change, Trial primary completion date: Neuroprotective Effects of Lithium in Patients With Small Cell Lung Cancer Undergoing Radiation Therapy to the Brain (clinicaltrials.gov) - May 19, 2017
P1/2, N=19, Active, not recruiting, Sponsor: Washington University School of Medicine
Active, not recruiting --> Completed Recruiting --> Active, not recruiting | N=26 --> 19 | Trial primary completion date: Oct 2017 --> Aug 2016
- | lithium carbonate ER / Generic mfg.
New P4 trial: Guidance Model of Standardized Treatment of Antidepressants in Bipolar Disorder (clinicaltrials.gov) - May 10, 2017
P4, N=100, Recruiting, Sponsor: Peking University
- | lithium carbonate ER / Generic mfg.
Trial primary completion date: The Neurotrophic Effects of Lithium Carbonate Following Stroke: A Feasibility Study (clinicaltrials.gov) - Apr 27, 2017
P3, N=35, Recruiting, Sponsor: Sunnybrook Health Sciences Centre
Recruiting --> Active, not recruiting | N=26 --> 19 | Trial primary completion date: Oct 2017 --> Aug 2016 Trial primary completion date: Mar 2017 --> Mar 2018
- | lithium carbonate ER / Generic mfg.
Trial completion, Enrollment change: Lithium Carbonate and Tretinoin in Treating Patients With Relapsed or Refractory Acute Myeloid Leukemia (clinicaltrials.gov) - Apr 27, 2017
P1, N=12, Completed, Sponsor: Paolo Caimi, MD
Trial primary completion date: Mar 2017 --> Mar 2018 Active, not recruiting --> Completed | N=24 --> 12
- | lithium carbonate ER / Generic mfg.
Enrollment open: Low-Dose Lithium for the Treatment of Behavioral Symptoms in Frontotemporal Dementia (clinicaltrials.gov) - Apr 19, 2017
P2, N=60, Recruiting, Sponsor: Columbia University
Active, not recruiting --> Completed | N=24 --> 12 Not yet recruiting --> Recruiting
- | lithium carbonate ER / Generic mfg.
Enrollment open, Trial initiation date: Lithium for Fracture Treatment: a Double Blind Randomized Controlled Trial (LiFT) (clinicaltrials.gov) - Apr 17, 2017
P2, N=160, Recruiting, Sponsor: Sunnybrook Health Sciences Centre
Not yet recruiting --> Recruiting Not yet recruiting --> Recruiting | Initiation date: Jan 2017 --> Apr 2017
- | lithium carbonate ER / Generic mfg.
Enrollment open: OPTIMUM: Optimizing Outcomes of Treatment-Resistant Depression in Older Adults (clinicaltrials.gov) - Apr 11, 2017
P4, N=1500, Recruiting, Sponsor: Washington University School of Medicine
Not yet recruiting --> Recruiting | Initiation date: Jan 2017 --> Apr 2017 Not yet recruiting --> Recruiting
- |||| Caplyta (lumateperone) - Intra / Cellular Therapies
Trial primary completion date: Clinical Trial Evaluating ITI-007 as an Adjunctive Therapy to Lithium or Valproate for the Treatment of Bipolar Depression (clinicaltrials.gov) - Mar 17, 2017
P3, N=550, Recruiting, Sponsor: Intra-Cellular Therapies, Inc.
Not yet recruiting --> Recruiting Trial primary completion date: Oct 2017 --> Feb 2019
- | lithium carbonate ER / Generic mfg.
New P4 trial, Surgery: LSCAKI: Lithium in Acute Kidney Injury (clinicaltrials.gov) - Feb 16, 2017
P4, N=50, Not yet recruiting, Sponsor: Lifespan
- lithium carbonate ER / Generic mfg.
Trial primary completion date: Neuroprotective Effects of Lithium in Patients With Small Cell Lung Cancer Undergoing Radiation Therapy to the Brain (clinicaltrials.gov) - Jan 30, 2017
P1/2, N=26, Recruiting, Sponsor: Washington University School of Medicine
Trial primary completion date: Oct 2017 --> Feb 2019 Trial primary completion date: Jul 2017 --> Oct 2017
- lithium carbonate ER / Generic mfg.
Enrollment change: SMART: Sequential Multiple Assignment Treatment for Bipolar Disorder (clinicaltrials.gov) - Jan 30, 2017
P4, N=110, Completed, Sponsor: The University of Texas Health Science Center at San Antonio
Trial primary completion date: Jul 2017 --> Oct 2017 N=200 --> 110
- lithium carbonate ER / Generic mfg.
Trial completion: SMART: Sequential Multiple Assignment Treatment for Bipolar Disorder (clinicaltrials.gov) - Jan 26, 2017
P4, N=200, Completed, Sponsor: The University of Texas Health Science Center at San Antonio
N=200 --> 110 Active, not recruiting --> Completed
- lithium carbonate ER / Generic mfg.
Trial completion, Enrollment change, Trial primary completion date: Evaluation of Lithium and It's Effect on Clinically Localized Prostate Cancer (clinicaltrials.gov) - Jan 9, 2017
P1, N=11, Completed, Sponsor: University of Kansas Medical Center
Active, not recruiting --> Completed Recruiting --> Completed | N=18 --> 11 | Trial primary completion date: Apr 2016 --> Aug 2016
- lithium carbonate ER / Generic mfg.
Trial initiation date: Low-Dose Lithium for the Treatment of Behavioral Symptoms in Frontotemporal Dementia (clinicaltrials.gov) - Jan 6, 2017
P2, N=60, Not yet recruiting, Sponsor: Columbia University
Recruiting --> Completed | N=18 --> 11 | Trial primary completion date: Apr 2016 --> Aug 2016 Initiation date: Sep 2016 --> Dec 2016
- lithium carbonate ER / Generic mfg., ketamine / Generic mfg.
Trial completion: Ketamine Plus Lithium in Treatment-Resistant Depression (clinicaltrials.gov) - Nov 30, 2016
P2, N=46, Completed, Sponsor: Icahn School of Medicine at Mount Sinai
Initiation date: Sep 2016 --> Dec 2016 Recruiting --> Completed
- | lithium carbonate ER / Generic mfg.
New P4 trial: OPTIMUM: Optimizing Outcomes of Treatment-Resistant Depression in Older Adults (clinicaltrials.gov) - Nov 9, 2016
P4, N=1500, Not yet recruiting, Sponsor: Washington University School of Medicine
- lithium carbonate ER / Generic mfg.
Trial primary completion date: The Neurotrophic Effects of Lithium Carbonate Following Stroke: A Feasibility Study (clinicaltrials.gov) - Oct 25, 2016
P3, N=35, Recruiting, Sponsor: Sunnybrook Health Sciences Centre
Recruiting --> Completed Trial primary completion date: Jul 2016 --> Mar 2017
- | lithium carbonate ER / Generic mfg.
New P4 trial, HEOR, Cost effectiveness: Cost- Effectiveness and Quality of Life Assessment in Bipolar Disorder Depressive Episode (clinicaltrials.gov) - Sep 28, 2016
P4, N=78, Completed, Sponsor: Federal University of Rio Grande do Sul
- Biomarker, New P4 trial: Gao NARASD Lithium Study (clinicaltrials.gov) - Sep 21, 2016
P4, N=50, Recruiting, Sponsor: Keming Gao
- | lithium carbonate ER / Generic mfg.
New P4 trial, HEOR, Cost effectiveness: Cost- Effectiveness and Quality of Life Assessment in Major Depression Disorder (clinicaltrials.gov) - Sep 15, 2016
P4, N=68, Completed, Sponsor: Federal University of Rio Grande do Sul
- lithium carbonate ER / Generic mfg.
New trial, HEOR: Longitudinal Comparative Effectiveness of Bipolar Disorder Therapies (clinicaltrials.gov) - Sep 8, 2016
P=N/A, N=1000000, Not yet recruiting, Sponsor: University of New Mexico
- lithium carbonate ER / Generic mfg.
Trial primary completion date: Neuroprotective Effects of Lithium in Patients With Small Cell Lung Cancer Undergoing Radiation Therapy to the Brain (clinicaltrials.gov) - Sep 1, 2016
P1/2, N=26, Recruiting, Sponsor: Washington University School of Medicine
Trial primary completion date: Jul 2016 --> Mar 2017 Trial primary completion date: Jul 2016 --> Jul 2017
- lithium carbonate ER / Generic mfg.
Trial primary completion date: Prevention of Relapse & Recurrence of Bipolar Depression (clinicaltrials.gov) - Aug 31, 2016
P4, N=200, Active, not recruiting, Sponsor: University of Pennsylvania
Trial primary completion date: Jul 2016 --> Jul 2017 Trial primary completion date: Jun 2015 --> Sep 2016
- lithium carbonate ER / Generic mfg., ketamine / Generic mfg.
Trial primary completion date: Ketamine Plus Lithium in Treatment-Resistant Depression (clinicaltrials.gov) - Aug 11, 2016
P2, N=45, Recruiting, Sponsor: Icahn School of Medicine at Mount Sinai
Trial primary completion date: Jun 2015 --> Sep 2016 Trial primary completion date: Jun 2016 --> Oct 2016
- | lithium carbonate ER / Generic mfg.
New P2 trial: Low-Dose Lithium for the Treatment of Behavioral Symptoms in Frontotemporal Dementia (clinicaltrials.gov) - Aug 10, 2016
P2, N=60, Not yet recruiting, Sponsor: Johns Hopkins University
- Trial completion: Genetic Predictors of Lithium Response in Bipolar Disorder (clinicaltrials.gov) - Jul 28, 2016
P=N/A, N=130, Completed, Sponsor: VA Office of Research and Development
Trial primary completion date: Jun 2016 --> Oct 2016 Recruiting --> Completed
- lithium carbonate ER / Generic mfg.
Trial primary completion date: PET and MRI Brain Imaging of Bipolar Disorder (clinicaltrials.gov) - Jul 19, 2016
P=N/A, N=76, Recruiting, Sponsor: Stony Brook University
Recruiting --> Completed Trial primary completion date: May 2016 --> May 2017
- lithium carbonate ER / Generic mfg.
Trial primary completion date: SMART: Sequential Multiple Assignment Treatment for Bipolar Disorder (clinicaltrials.gov) - Jun 23, 2016
P4, N=200, Active, not recruiting, Sponsor: The University of Texas Health Science Center at San Antonio
Trial primary completion date: May 2016 --> May 2017 Trial primary completion date: Apr 2016 --> Dec 2016
- lithium carbonate ER / Generic mfg.
Trial initiation date, Trial primary completion date: Evaluation of Lithium as a Glycogen-Synthase-Kinase-3 (GSK-3) Inhibitor in Mild Cognitive Impairment (clinicaltrials.gov) - May 19, 2016
P=N/A, N=20, Not yet recruiting, Sponsor: University of Dundee
Trial primary completion date: Apr 2016 --> Dec 2016 Initiation date: Nov 2015 --> Jun 2016 | Trial primary completion date: May 2016 --> Sep 2016
- lithium carbonate ER / Generic mfg.
Trial completion: A Pilot Study of Lithium in Progressive Multiple Sclerosis (clinicaltrials.gov) - Mar 31, 2016
P1/2, N=20, Completed, Sponsor: VA Office of Research and Development
Initiation date: Nov 2015 --> Jun 2016 | Trial primary completion date: May 2016 --> Sep 2016 Active, not recruiting --> Completed
- | lithium carbonate ER / Generic mfg.
Trial completion: Maintenance Therapies in Bipolar Disorders (clinicaltrials.gov) - Feb 27, 2016
P3, N=0, Completed, Sponsor: University of Pittsburgh
Active, not recruiting --> Completed No longer recruiting --> Completed
- lithium carbonate ER / Generic mfg.
Trial primary completion date: In Vivo Lithium Treatment Effects on Gene Expression Levels in Lymphoblastoid Cell Lines From Human Healthy Subjects (clinicaltrials.gov) - Feb 12, 2016
P1, N=20, Recruiting, Sponsor: Nova Scotia Health Authority
No longer recruiting --> Completed Trial primary completion date: May 2013 --> Jul 2017
- lithium carbonate ER / Generic mfg.
Trial completion, Trial primary completion date: Study to Evaluate the Efficacy of Lithium Carbonate in Spinal Cord Injury Patients With Neuropathic Pain (clinicaltrials.gov) - Jan 28, 2016
P2, N=60, Completed, Sponsor: China Spinal Cord Injury Network
Trial primary completion date: May 2013 --> Jul 2017 Active, not recruiting --> Completed | Trial primary completion date: Dec 2015 --> Jun 2015
- lithium carbonate ER / Generic mfg.
Enrollment change, Trial withdrawal: Lithium Augmentation for Hyperarousal Symptoms of Post Traumatic Stress Disorder: Pilot Study (clinicaltrials.gov) - Jan 7, 2016
P1, N=0, Withdrawn, Sponsor: VA Eastern Colorado Health Care System
Active, not recruiting --> Completed | Trial primary completion date: Dec 2015 --> Jun 2015 N=50 --> 0 | Recruiting --> Withdrawn
- |||||| Caplyta (lumateperone) - Intra / Cellular Therapies
Enrollment open: Clinical Trial Evaluating ITI-007 as an Adjunctive Therapy to Lithium or Valproate for the Treatment of Bipolar Depression (clinicaltrials.gov) - Dec 24, 2015
P3, N=550, Recruiting, Sponsor: Intra-Cellular Therapies, Inc.
N=50 --> 0 | Recruiting --> Withdrawn Not yet recruiting --> Recruiting
- New P2 trial, Combination therapy: ARIQUELI-ME: Efficacy of Memantine add-on in the Treatment of Bipolar Disorder (Type I) Nonresponders or Partial Responders Patients (clinicaltrials.gov) - Dec 15, 2015
P2, N=44, Recruiting, Sponsor: University of Sao Paulo