- |||||||||| INXN-4001 / Precigen
Enrollment closed: Novel INXN-4001 Triple Effector Plasmid in Heart Failure (clinicaltrials.gov) - Nov 18, 2019
P1, N=12, Active, not recruiting,
Active, not recruiting --> Completed | Trial completion date: Nov 2020 --> Aug 2020 Recruiting --> Active, not recruiting
- |||||||||| INXN-4001 / Intrexon
Safety of First in Human Triple-Gene Therapy Candidate for Heart Failure Patients (Zone 4, Science and Technology Hall) - Oct 17, 2019 - Abstract #AHA2019AHA_8664;
The INXN-4001 investigational new drug is a non-viral, multigenic, triple effector plasmid designed with a self-cleaving linker to constitutively express human SDF-1α, S100A1, and VEGF-165 to affect progenitor cell recruitment, calcium metabolism, and angiogenesis... This is the first in-human experience with a triple gene construct.
- |||||||||| INXN-4001 / Precigen
Trial completion date, Trial primary completion date: Novel INXN-4001 Triple Effector Plasmid in Heart Failure (clinicaltrials.gov) - Aug 30, 2019
P1, N=12, Recruiting,
This is the first in-human experience with a triple gene construct. Trial completion date: Jun 2020 --> Sep 2020 | Trial primary completion date: Dec 2019 --> Mar 2020
- |||||||||| INXN-4001 / Precigen
Trial completion date, Trial primary completion date: Novel INXN-4001 Triple Effector Plasmid in Heart Failure (clinicaltrials.gov) - May 21, 2019
P1, N=12, Recruiting,
Trial completion date: Jun 2020 --> Sep 2020 | Trial primary completion date: Dec 2019 --> Mar 2020 Trial completion date: Dec 2019 --> Jun 2020 | Trial primary completion date: Apr 2019 --> Dec 2019
- |||||||||| INXN-4001 / Precigen
Enrollment open: Novel INXN-4001 Triple Effector Plasmid in Heart Failure (clinicaltrials.gov) - Apr 11, 2018
P1, N=12, Recruiting,
Trial completion date: Dec 2019 --> Jun 2020 | Trial primary completion date: Apr 2019 --> Dec 2019 Not yet recruiting --> Recruiting
- |||||||||| INXN-4001 / Precigen
Trial initiation date, Trial primary completion date: Novel INXN-4001 Triple Effector Plasmid in Heart Failure (clinicaltrials.gov) - Apr 2, 2018
P1, N=12, Not yet recruiting,
Not yet recruiting --> Recruiting Initiation date: Jan 2018 --> Apr 2018 | Trial primary completion date: Dec 2019 --> Apr 2019
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