| Triplixam (perindopril arginine/amlodipine/indapamide) / Servier |
| Recruiting | 4 | 2500 | Europe | Phase C: Eplerenone, Eplerenone, Phase C: Spironolactone, Spironolactone, Phase C: Torasemide, Torasemide, Phase B: Triplixam / Elestar HCT, Triple Single Pill Combination: Triplixam / Elestar HCT, Phase A: Confirmation of uncontrolled hypertension | National Institute of Cardiology, Warsaw, Poland | Hypertension | 12/25 | 12/25 | | |
| Completed | 4 | 1981 | RoW | Amlodipine + Perindopril, Perindopril + Indapamide, Amlodipine + Indapamide | Centre for Chronic Disease Control, India, All India Institute of Medical Sciences, New Delhi, Imperial College London | Primary Hypertension | 08/24 | 09/24 | | |
2020-004891-16: A comparison of a single-pill combination of perindopril/indapamide/amlodipine/bisoprolol with perindopril,indapamide and amlodipine in patients with essential hypertension whose blood pressure remains high on perindopril, indapamide and amlodipine treatment. |
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| Ongoing | 3 | 968 | Europe, RoW | S05179, S05179, Capsule, hard, Film-coated tablet, COVERSYL®, Norvasc®, FLUDEX® | Institut de Recherches Internationales Servier, Servier Portugal - Especialidades Farmaceuticas, Lda., INSTITUT DE RECHERCHES INTERNATIONALES SERVIER, ADIR, Servier Portugal - Especialidades Farmacêuticas, Lda., Servier Portugal - Especialidades Farmaceuticas, Lda. | Hypertension, High blood pressure, Diseases [C] - Cardiovascular Diseases [C14] | | | | |
NCT05820880: Efficacy and Safety of Perindopril 5 mg / Indapamide 1.25 mg / Amlodipine 5 mg Fixed Combination in Hypertension |
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| Completed | 3 | 532 | RoW | Fixed [Per/Ind/Aml], Free [Per/Ind + Aml] | Institut de Recherches Internationales Servier | Hypertension | 02/22 | 02/22 | | |
NCT05940909: Bioequivalence Study of Perindopril /Amlodipine/Indapamide 8 mg (10 mg)/2.5 mg/10 mg Tablets in Healthy Volunteers Under Fasting Conditions |
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| Recruiting | 1 | 50 | RoW | Perindopril/Indapamide/Amlodipine 8 mg/2.5 mg/10 mg tablet / Triplixam® 10 mg/2.5 mg/10 mg tablet, The test product / The reference product | Pharmtechnology LLC | Bioequivalence | 08/23 | 11/23 | | |
TRIPTYCH, NCT06259175: Evaluation of the Antihypertensive effectIveness, Tolerability, and Adherence With Amlodipine/ Indapamide/ Perindopril Triple Single-pill Combination in Hypertensive Patients Without Concomitant Antihypertensive Therapy |
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| Not yet recruiting | N/A | 375 | NA | Amlodipine 5 mg + indapamide 1.25 mg + perindopril 5 mg, Amlodipine 5 mg + indapamide 2.5 mg + perindopril 10 mg, Amlodipine 10 mg + indapamide 2.5 mg + perindopril 10 mg | Servier Russia | Arterial Hypertension, HTN | 12/24 | 02/25 | | |
