lidocaine topical / Generic mfg. 
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  • ||||||||||  lidocaine topical / Generic mfg.
    Intractable Headache Relieved With Intravenous Lidocaine (Hall C) -  Aug 15, 2022 - Abstract #ASA2022ASA_5082;    
    We then performed a topical SPG block with some improvement. Patient was then offered a trial of 24hr IV lidocaine infusion which led to complete resolution of her pain.
  • ||||||||||  sevoflurane / Generic mfg., lidocaine topical / Generic mfg., dexmedetomidine / Generic mfg.
    Induction Of General Anesthesia In A Patient With A Large Anterior Mediastinal Mass With Mass Effect On The Right Heart (Hall C) -  Aug 15, 2022 - Abstract #ASA2022ASA_4868;    
    However, given the tumor's mass effect on the heart, ECMO support was requested to be on standby during induction. After arterial line placement, inhalational induction with maintenance of spontaneous ventilation was performed using a combination of sevoflurane, dexmedetomidine, midazolam, ketamine, and airway topicalization with 4% lidocaine.
  • ||||||||||  Three Hour Awake Vocal Cord Visualization During Type 1 Thyroplasty (Hall C) -  Aug 15, 2022 - Abstract #ASA2022ASA_3932;    
    The surgeon requested that precedex be avoided due to previous inconsistent results. Given the patient’s medical history, we opted for small doses of midazolam and a remifentanil infusion after adequate topicalization of vocal cords with lidocaine.
  • ||||||||||  lidocaine topical / Generic mfg.
    Awake Tracheostomy With Vocal Cord Dysfunction Due To Cancer (Hall C) -  Aug 15, 2022 - Abstract #ASA2022ASA_2510;    
    Patient brought to OR with Bipap, no sedation was administered and ENT proceeded with tracheostomy while offering continuous reassurance. We will discuss evidence-based strategies for difficult airway and medication management.
  • ||||||||||  lidocaine topical / Generic mfg.
    Acute Respiratory Decompensation With Substantial Anterior Mediastinal Mass (Hall C) -  Aug 15, 2022 - Abstract #ASA2022ASA_1783;    
    ECMO team unable to attempt femoral cannulation prior to airway due to inability to tolerate supine positioning (patient sitting >90 degree angle, tripoding) and also unable to perform neck cannulation given SVC syndrome. Awake fiberoptic attempted and successfully managed with topicalization (nebulized lidocaine) and reinforced endotracheal tube.
  • ||||||||||  lidocaine topical / Generic mfg.
    Crossbow Vs Fiberoptic (Hall C) -  Aug 15, 2022 - Abstract #ASA2022ASA_954;    
    2% lidocaine was atomized over the cords and endotracheal tube was placed. Surgery removed the arrow without complication.The following day, he was extubated in the ICU without difficulty.
  • ||||||||||  lidocaine topical / Generic mfg., tramadol hydrochloride / Generic mfg.
    New P4 trial:  Lidocaine Spray for Pain Control in Rib Fractures (clinicaltrials.gov) -  Aug 15, 2022   
    P4,  N=48, Completed, 
  • ||||||||||  lidocaine topical / Generic mfg.
    Journal:  The use of lidocaine spray (Xylocaine) as a topical anaesthetic for minor ear procedures. (Pubmed Central) -  Aug 6, 2022   
    In the meantime, special precautions are warranted in patients receiving combined therapy. Xylocaine spray is simple to administer, rapid-acting and well tolerated by patients for anaesthesia of the tympanic membrane during minor ear procedures in the out-patient setting.
  • ||||||||||  lidocaine topical / Generic mfg.
    Trial completion date, Trial primary completion date:  To Evaluate Reduction of Pain in Wounds Treatment Previously Applying Lidocaine Topical Solution vs Placebo. (clinicaltrials.gov) -  Aug 5, 2022   
    P3,  N=46, Recruiting, 
    Lidocaine topical system 1.8% demonstrated superior adhesion relative to the three lidocaine-containing OTC products over the 12-hour treatment period. Trial completion date: Apr 2021 --> Oct 2023 | Trial primary completion date: Apr 2021 --> Oct 2023
  • ||||||||||  lidocaine topical / Generic mfg.
    Journal:  Activation of peripheral TRPM8 mitigates ischemic stroke by topically applied menthol. (Pubmed Central) -  Jul 30, 2022   
    Our results suggested that activation of peripheral TRPM8 expressed in the derma tissue of limbs with sufficient concentration of menthol is beneficial to stroke recovery. Topical application of menthol on hands and feet could be a novel and simple-to-use therapeutic strategy for stroke patients.
  • ||||||||||  lidocaine topical / Generic mfg.
    Journal:  Preparation and Optimization of an Ultraflexible Liposomal Gel for Lidocaine Transdermal Delivery. (Pubmed Central) -  Jul 29, 2022   
    The local anesthetic efficacy of the formulation was investigated by an in vivo tail-flick test in rats. Our findings suggested that this topical gel formulated with ultraflexible liposomal lidocaine has enhanced skin permeation ability, as well as an improved local analgesic effect from the lidocaine.
  • ||||||||||  lidocaine topical / Generic mfg.
    Journal:  Local hyperexcitability of C-nociceptors may predict responsiveness to topical lidocaine in neuropathic pain. (Pubmed Central) -  Jul 23, 2022   
    Electrically assessed C-nociceptor excitability identified by slowly depolarizing electrical stimuli might reflect the source of neuropathic pain in some patients and can be useful for patient stratification to predict potential success of topical analgesics. Central neuronal circuitry assessment reflected by increased pain in control skin associated with higher HADS scores suggest central sensitization phenomena in a sub-population of neuropathic pain patients.
  • ||||||||||  lidocaine topical / Generic mfg.
    Journal:  Stevens Johnson Syndrome: Past, Present, and Future Directions Gynecologic Manifestations and Management in SJS/TEN. (Pubmed Central) -  Jul 23, 2022   
    Of the 26 females with vulvar involvement, 31% (n = 8) had no vulvar treatment recommendations with the remaining 69% having some documentation that ranged from gauze placement only (19%) to topical lidocaine, barrier cream, antibiotic or antifungal cream/ ointment, lubricant, or topical steroid ointment (50%)...The role of local estrogen and vaginal laser still needs to be explored. Pelvic floor physical therapy might play a significant role in rehabilitation and has yet to be studied.
  • ||||||||||  lidocaine topical / Generic mfg.
    Trial primary completion date:  Inhibition of Non-histaminergic Pruritus Applied Using 3 Different Pruritogens (clinicaltrials.gov) -  Jul 20, 2022   
    P=N/A,  N=22, Recruiting, 
    Pelvic floor physical therapy might play a significant role in rehabilitation and has yet to be studied. Trial primary completion date: May 2022 --> Aug 2022
  • ||||||||||  lidocaine topical / Generic mfg.
    New P4 trial:  Conservative Management of Cutaneous Abscess (clinicaltrials.gov) -  Jul 15, 2022   
    P4,  N=300, Not yet recruiting, 
  • ||||||||||  Tetralysal (lymecycline) / Galderma
    Maculopapular cutaneous mastocytosis mimicking seborrhoeic folliculitis () -  Jul 15, 2022 - Abstract #BAD2022BAD_756;    
    This had been widely investigated and managed as follicular eruption with long-term antibiotics in the past (lymecycline and doxycycline)...Urgent skin biopsies were carried out using lidocaine without adrenaline...He was started on fexofenadine 180 mg twice daily with topical mometasone furoate 0·1% cream, which resulted in a slight improvement...Gastrointestinal symptoms are second only to pruritus and seen in 60–80% of patients with systemic disease. This case report highlights the importance of re-evaluation, a high degree of clinical suspicion and clinicopathological correlation in arriving at a diagnosis of a rare skin disease with variable presentations as they are often misdiagnosed and underdiagnosed.
  • ||||||||||  lidocaine topical / Generic mfg.
    Journal:  Preparation and Characterization of Lidocaine-Loaded, Microemulsion-Based Topical Gels. (Pubmed Central) -  Jun 30, 2022   
    In-vitro release and ex-vivo permeation studies on MBGs showed significantly higher drug release and permeation in comparison to the marketed topical gel. Developed MBG formulations demonstrated greater potential for transdermal delivery of lidocaine and advantage over the commercially available gel product, and therefore, they may be considered as potential vehicles for the topical delivery of lidocaine.
  • ||||||||||  lidocaine topical / Generic mfg.
    Retrospective data, Review:  Acupuncture to Improve Patient Discomfort During Upper Gastrointestinal Endoscopy: Systematic Review and Meta-Analysis. (Pubmed Central) -  Jun 22, 2022   
    It was found that acupuncture plus topical pharyngeal anesthesia with lidocaine hydrochloride (TPALH) resulted in greater improvements regarding visual analog scale (VAS) scores and the incidence of nausea and vomiting (INV) when compared with TPALH alone...More rigorously designed RCTs are needed to inform clinical decision-making. PROSPERO [CRD42014008966].
  • ||||||||||  lidocaine topical / Generic mfg.
    Trigeminal Neuralgia (Plenary Hall) -  Jun 20, 2022 - Abstract #WIP2022WIP_167;    
    Beside these three approaches, Gamma Knife, Siber Knife, Cryotherapy, Peripheric blocks, %10 lidocaine injection, Peripheric glycerol injection may also be used...However, treatment selection remains an inexact science in the absence of high quality outcomes data. In addition to incorporating these technical advances, future studies must overcome the patient heterogeneity, procedural variation, and nonstandard outcomes that limit interpretation of the existing literature.
  • ||||||||||  lidocaine topical / Generic mfg.
    Topical Analgesic Drug Therapies: Trpv1 Receptor Modulators and Beyond (Plenary Hall) -  Jun 20, 2022 - Abstract #WIP2022WIP_146;    
    Treatment options for neuropathic pain range from therapeutic desensitization, topical medication management (lidocaine, capsaicin, compounded creams), oral medication management (antiepileptics, tricyclic antidepressants, NSAIDs, opioids, cannabinoids, etc), interventional injections (nerve blocks, radiofrequency ablation, hydrodissection), and neuromodulation (peripheral nerve stimulation, SCS, TMS, etc)...There still remains significant risk factors with the utilization of oral anti-neuropathic agents as well as more invasive interventional procedures. As such, looking to follow the stepwise and multimodal approach to the treatment of neuropathic pain, it is suggested that trial of topical anti-neuropathic agents such as, concentrated 8% capsaicin, in conjunction with minimally invasive peripheral nerve stimulation strongly be considered as a first line options combatting the allodynia associated most Chronic Pain Syndromes.
  • ||||||||||  lidocaine topical / Generic mfg.
    Journal:  Endometrial Biopsy: Tips and Pitfalls. (Pubmed Central) -  Jun 19, 2022   
    Nonsteroidal anti-inflammatory drugs can be administered orally before the procedure, and topical lidocaine can be applied to the cervix before starting the procedure to reduce procedure-associated pain...Patients should be referred for further evaluation if the procedure fails or an insufficient sample is obtained. Postmenopausal women and women with persistent or recurrent symptoms should receive further evaluation even when biopsy results are normal because blind sampling may miss focal lesions.
  • ||||||||||  remifentanil / Generic mfg., lidocaine topical / Generic mfg.
    Mucopolysaccharidosis, when the first plan doesn’t work: a case report (Virtual Platform - Poster section) -  Jun 17, 2022 - Abstract #Euroanaesthesia2022Euroanaesthesia_658;    
    Secondly, a TCI- based sedation with remifentanil was started and a first airway approach was attempted by nasal fiberscopic intubation, maintaining spontaneous ventilation...Preoperative evaluation and knowledge of the MPS pathophysiology are essential to anticipate any obstacles and achieve the best outcome. Although awake intubation using flexible fiberscope is usually the first choice, alternative methods should be anticipated for the best outcome.
  • ||||||||||  fentanyl citrate / Generic mfg., lidocaine topical / Generic mfg., midazolam hydrochloride / Generic mfg.
    Goldenhar syndrome - a case report of a difficult airway approach (Virtual Platform - Poster section) -  Jun 17, 2022 - Abstract #Euroanaesthesia2022Euroanaesthesia_657;    
    The patient was sedated using 1 mcg/kg of fentanyl and 0.5mg/Kg of propofol, ensuring effective spontaneous ventilation...A full diagnosis and comorbidities optimization should occur before an elective procedure. Early recognition of difficult airway allowing for timely planning and management is crucial for patient safety.
  • ||||||||||  remifentanil / Generic mfg., lidocaine topical / Generic mfg.
    Perioperative management of a patient with Madelung’s disease and undiagnosed obstructive sleep apnoea syndrome – a case report (Virtual Platform - Poster section) -  Jun 17, 2022 - Abstract #Euroanaesthesia2022Euroanaesthesia_641;    
    Topical anaesthesia with lidocaine 1% was performed while preoxygenation was initiated...After checking the correct tube positioning, induction of general anaesthesia was performed with propofol and remifentanil...However, given the OSA signs presented, our patient needed CPAP treatment.Learning points: This case highlights the importance of a detailed assessment of airway deformities and compression symptoms in patients with MD. Even though anaesthetic plan should minimize factors that contribute to postoperative respiratory complications, the typical localization of fat tissue masses constitutes a serious concern to anaesthetic practice.
  • ||||||||||  Analgesia and sedation concepts for the placements of peripheral regional anesthesia: pilot-RCT (Virtual Platform - Poster section) -  Jun 17, 2022 - Abstract #Euroanaesthesia2022Euroanaesthesia_490;    
    It is also questionable whether the patient has to be completely awake during the placement of regional anaesthesia.Analgosedation with remifentanil seems to lead to the lowest pain while best ensuring patients’ wellbeing for pre-operative regional anaesthesia. Optimal approach has to be adjusted according to the patient needs, medical personnel and their expertise and a hospital’s logistics.
  • ||||||||||  Subtotal mandibulectomy for ameloblastoma resection and reconstruction using a free fibula flap: anesthetic approach case report (Virtual Platform - Poster section) -  Jun 17, 2022 - Abstract #Euroanaesthesia2022Euroanaesthesia_474;    
    An awake intubation approach using dexmedetomidine, ketamine and laryngotracheal topical anesthesia with nebulized lidocaine was performed...Anesthesia was maintained with remifentanil and propofol infusion combined with epidural block...When infused alone at the end of surgery, it led to a smooth emergence, which is imperative in these cases. Pain control is also of great importance, with regional analgesic techniques assuming a relevant role.
  • ||||||||||  Airway management of a paediatric patient with Goldenhar syndrome (Poster eBoard 5) -  Jun 17, 2022 - Abstract #Euroanaesthesia2022Euroanaesthesia_36;    
    A ketamine bolus was also administered...Scoliosis, micrognathia and cervical extension restriction are risk factors for a difficult intubation. Reduction of functional, residual capacity and total lung capacity can also lead to ventilation problems.(2)
  • ||||||||||  lidocaine topical / Generic mfg.
    Journal:  Where does postmenopausal dyspareunia hurt? A cross-sectional report. (Pubmed Central) -  Jun 11, 2022   
    Participants described their pain as "burning" and "dry." Tenderness was most severe and most consistently located at the vulvar vestibule. Correlating the symptom of dyspareunia with genital examination findings may further our understanding of treatment outcomes for GSM.
  • ||||||||||  lidocaine topical / Generic mfg.
    Journal:  Changing the paradigm in postherpetic neuralgia treatment: lidocaine 700 mg medicated plaster. (Pubmed Central) -  Jun 11, 2022   
    Correlating the symptom of dyspareunia with genital examination findings may further our understanding of treatment outcomes for GSM. LMP is one of the best currently available treatment options for PHN patients balancing good efficacy with an excellent tolerability profile and can therefore be considered for use as a first-line treatment for PHN.