- |||||||||| lidocaine topical / Generic mfg.
Retrospective data, Review, Journal: Topical Anesthetics and Premature Ejaculation: A Systematic Review and Meta-Analysis. (Pubmed Central) - Sep 7, 2023
Additionally, it was found that lidocaine gel was more efficient than paroxetine or sildenafil (P = 0.04; P<0.00001). In conclusion, topical anesthetics increase IELT in men with premature ejaculation more effectively than placebo, sildenafil, tadalafil, paroxetine, and dapoxetine.
- |||||||||| lidocaine topical / Generic mfg.
Trial completion date, Trial initiation date, Trial primary completion date: USTMS: Uddevalla Sk (clinicaltrials.gov) - Sep 1, 2023
P=N/A, N=40, Enrolling by invitation,
Although the average maintenance time of anesthesia was longer in the lidocaine group, there was no difference in the associated complications and pain control. Trial completion date: Mar 2025 --> Sep 2025 | Initiation date: Jan 2023 --> Sep 2023 | Trial primary completion date: Mar 2025 --> Sep 2025
- |||||||||| lidocaine topical / Generic mfg., carvedilol / Generic mfg., pregabalin / Generic mfg.
Red scrotum syndrome: A clinical and therapeutic challenge (e-Poster Hall) - Aug 30, 2023 - Abstract #EADV2023EADV_4306;
The exact etiopathogeneis of RSS is still unknown. The suggested mechanisms are rebound vasodilation after prolonged topical corticosteroid use and localized erythromelalgia.
- |||||||||| lidocaine topical / Generic mfg.
vulvar syringomas - common lesions at an unusual site (e-Poster Hall) - Aug 30, 2023 - Abstract #EADV2023EADV_4136;
They are usually asociated with pruritus, being the main complaint of the patients. Differential diagnosis of vulvar syringomas should include Fox-Fordyce disease, multiple epidermal cysts, condyloma acuminata and senile angiomas.
- |||||||||| lidocaine topical / Generic mfg.
The Efficacy of Topical Lidocaine Treatment in Postherpetic Neuropathic Itch -A Case Study (Exhibit Hall) - Aug 23, 2023 - Abstract #ASA2023ASA_5384;
Two months after treatment, the patient no longer complained of an intractable itching sensation or pain. Although their effectiveness can vary depending on the underlying etiology and individual response, the positive effect of local anesthetics can aid the management of subsequent neuropathic itch symptoms.
- |||||||||| lidocaine topical / Generic mfg.
Awake Intubation in Patient With Ankylosing Spondylitis and Unstable C-Spine Fracture (South: Hall F) - Aug 23, 2023 - Abstract #ASA2023ASA_5165;
Glycopyrrolate, oxymetazoline, and lidocaine nebulizer were administered prior to arrival to the OR...An endotracheal tube was placed and secured using a fiberoptic bronchoscope. Patient demonstrated intact motor function prior to induction.
- |||||||||| lidocaine topical / Generic mfg.
Severe Erythromelalgia Complicated by Bilateral Leg Ulceration and Severe Pain Requiring Epidural Placement (Exhibit Hall) - Aug 23, 2023 - Abstract #ASA2023ASA_4761;
The only alleviating/effective therapies were cold water soaks and air conditioning which led to severe ulceration to his lower extremities complicated by infection and osteomyelitis requiring surgical debridement. He was admitted for an IV Lidocaine trial which was ineffective and ultimately required lumbar epidural to control his pain in addition to continued oral/IV pain regimen.
- |||||||||| lidocaine topical / Generic mfg.
Massive Multinodular Goiter With Diverse Presentation Concerning The Anesthesiologist (Exhibit Hall) - Aug 23, 2023 - Abstract #ASA2023ASA_3947;
Patient underwent left hemithyroidectomy and, despite challenges with patient cooperation, successful awake flexible fiberoptic intubation with lidocaine topicalization in sitting position was confirmed with NIMS tube 6.0. Extubation occurred in the OR uneventfully.
- |||||||||| A Novel Method for Intracavitary Cervical HDR Brachytherapy: Express Finger-Guided Implant Insertion at Simulation Table without Speculum, Cervical Dilatation, Sleeve, Anesthesia, or Sedation (Hall B2; In Person Only; Screen: 1) - Aug 22, 2023 - Abstract #ASTRO2023ASTRO_1837;
Express finger-guided intracavitary brachytherapy implant insertion at the simulation table without speculum, cervical dilatation, sleeve, anesthesia, or sedation is fast, effective, and an independent method that can be used in most cervical cancer patients to complete their planned brachytherapy treatment regardless of limited resources. Practice and dissemination of this innovative method is important especially when operative rooms and anesthesia support are limited (e.g. epidemics and closures) and in centers lacking such support.
- |||||||||| lidocaine topical / Generic mfg.
Journal: Anesthetic Effect of 2% Amitriptyline Versus 2% Lidocaine: A Comparative Evaluation. (Pubmed Central) - Aug 15, 2023
However, the VAS scores of anesthetic and analgesic pharmacodynamics properties of amitriptyline were statistically significantly lower than lidocaine, particularly at 25 and 35 minutes. Additionally, amitriptyline-induced anesthetic and analgesic pharmacology, especially pharmacokinetics properties, depends on the location and pattern of pain.
- |||||||||| lidocaine topical / Generic mfg.
Trial completion, Trial completion date, Trial primary completion date: Lidocaine Patch for Neck Pain (clinicaltrials.gov) - Aug 8, 2023
P=N/A, N=76, Completed,
Additionally, amitriptyline-induced anesthetic and analgesic pharmacology, especially pharmacokinetics properties, depends on the location and pattern of pain. Recruiting --> Completed | Trial completion date: Dec 2023 --> Jun 2023 | Trial primary completion date: Aug 2023 --> Jun 2023
- |||||||||| lidocaine topical / Generic mfg.
Trial completion: LULU: Lessons on Urethral Lidocaine in Urodynamics (clinicaltrials.gov) - Aug 1, 2023
P4, N=63, Completed,
Lidocaine may be preferable in clinical settings due to its large, multi-use vials and similar effects to ropivacaine. Recruiting --> Completed
- |||||||||| Journal: A Case Report of Refractory Postherpetic Neuralgia After Ramsay Hunt Syndrome Treated With Tympanic Nerve Neurectomy. (Pubmed Central) - Jul 31, 2023
Pain management to address postherpetic neuralgia includes facial nerve blocks, medications such as gabapentin, carbamazepine and botulinum toxin injections, and pulsed radiofrequency...The patient underwent a diagnostic myringotomy with topical application of lidocaine to the tympanic nerve...Chronic postherpetic neuralgia following Ramsay Hunt syndrome can cause significant impairment in a patient's quality of life. For patients with ear pain refractory to conservative management, a tympanic neurectomy can be considered.
- |||||||||| Traumatic Uvulitis: A Rare Complication of a Common Procedure (Exhibit Hall) - Jul 29, 2023 - Abstract #ACG2023ACG_2478;
While preprocedural EGD consents rarely discuss the risk of local trauma to the oropharynx, endoscopists should be aware of this potential post-procedural complication. Figure: Figure 1A: Elongated, edematous and hyperemic uvula 6 days after EGD Figure 1B: Persistently elongated uvula with resolved edematous uvula 14 days after EGD
- |||||||||| lidocaine topical / Generic mfg., midazolam hydrochloride / Generic mfg.
Journal: Topical Lidocaine And Or/ Intravenous Midazolam Before Radial Coronary Angiography To Prevent Radial Artery Spasm. (Pubmed Central) - Jul 28, 2023
Figure: Figure 1A: Elongated, edematous and hyperemic uvula 6 days after EGD Figure 1B: Persistently elongated uvula with resolved edematous uvula 14 days after EGD Cutaneous analgesia and procedural sedation before transradial access for coronary interventions were found to be associated with a substantial reduction in radial artery spasm and procedure-related discomfort.
- |||||||||| lidocaine topical / Generic mfg.
Journal, PD(L)-1 Biomarker, IO biomarker: Topical application of local anesthetics to melanoma increases the efficacy of anti-PD-1 therapy. (Pubmed Central) - Jul 27, 2023
Our data suggest that Pliaglis reduces melanoma growth through a direct effect on melanoma cells as well as through modulation of the immune response. The involvement of nervous system-related signaling in the inhibitory effect of Pliaglis on melanoma is inconclusive from our data.
- |||||||||| lidocaine topical / Generic mfg.
Journal: Flammability of Ocular Surface Lubricants. (Pubmed Central) - Jul 24, 2023
Certain lubricants could potentially become a fuel source when used in combination with hand-held high temperature battery cautery. Bipolar cautery was not associated with either increased conductivity or flammability with any of the lubricants tested.
- |||||||||| Peri-operative Pain Medicine In Multi-specialty Anesthesiology Practice For Patient With Long Covid Pain Syndrome (South: Hall D-7) - Jul 20, 2023 - Abstract #ASA2023ASA_2628;
Patient was on duloxetine daily and used muscle relaxant only as needed to relieve muscle tightness, spasms, diffuse body, joints, neck, and back pain.4.Patient reported inadequate pain control despite various IV opioids in PACU and had to stay overnight for observation and treatment...What are the options of oral pain medicine for acute postoperative pain in addition to worsening chronic diffuse body and joints pain?Patient failed previous tramadol, acetaminophen with codeine due to nausea and constipation with marginal pain relief...Perioperative patient care needs to minimize escalating opioids doses and minimize duration of opioid therapy for acute postoperative pain. It is crucial to advise patient compliance with COVID protective measures with goals to improve clinical postoperative outcomes and reduce overall healthcare cost.
- |||||||||| Incorporating Enhanced Recovery And Best Practices For Spine Surgery (South: Hall D-7) - Jul 20, 2023 - Abstract #ASA2023ASA_2322;
Would you order pregabalin or gabapentin for this patient?26...Could there be associated complications with the use of these medications?As you take the patient back to the operating room, a colleague suggests using lidocaine, ketamine, and dexmedetomidine intraoperatively.28...The surgeon asks if the patient is fine to go to the floor.30. Should the patient be admitted to the ICU, step-down unit or the ward?
- |||||||||| Anesthetic Induction For Pyloric Stenosis. A Functioning Peripheral Intravenous Catheter: Olive You But Do I Need You? (South: Hall D-7) - Jul 20, 2023 - Abstract #ASA2023ASA_2088;
Discuss the risks and benefits of each.You plan to induce anesthesia with propofol and rocuronium...Would you perform a spinal anesthetic?You decide to proceed with an inhalational induction with 100% Oxygen and 8% Sevoflurane. Intubation is facilitated with topical atomized lidocaine...Upon further investigation, you discover that during the operation, your resident gave morphine 0.1 mg/kgIV...The infant
- |||||||||| Here We Go Again: Acromegalic Patient For Repeat Pituitary Tumor Resection (South: Hall D-7) - Jul 20, 2023 - Abstract #ASA2023ASA_1530;
Current medications include metformin, insulin, lisinopril, metoprolol and PRN lorazepam for anxiety, which he admits to using for sleep on occasion.1...Should the patient receive perioperative dexamethasone for PONV prophylaxis?The surgeon begins topicalization of the nasal mucosa using injected lidocaine 1% with epinephrine...What additional labs would you request to determine the diagnosis?15. How would you treat this condition?
- |||||||||| Here We Go Again: Acromegalic Patient For Repeat Pituitary Tumor Resection (South: Hall D-7) - Jul 20, 2023 - Abstract #ASA2023ASA_1182;
Current medications include metformin, insulin, lisinopril, metoprolol and PRN lorazepam for anxiety, which he admits to using for sleep on occasion.1...Should the patient receive perioperative dexamethasone for PONV prophylaxis?The surgeon begins topicalization of the nasal mucosa using injected lidocaine 1% with epinephrine...What additional labs would you request to determine the diagnosis?15. How would you treat this condition?
- |||||||||| Incorporating Enhanced Recovery And Best Practices For Spine Surgery (South: Hall D-7) - Jul 20, 2023 - Abstract #ASA2023ASA_959;
Would you order pregabalin or gabapentin for this patient?26...Could there be associated complications with the use of these medications?As you take the patient back to the operating room, a colleague suggests using lidocaine, ketamine, and dexmedetomidine intraoperatively.28...The surgeon asks if the patient is fine to go to the floor.30. Should the patient be admitted to the ICU, step-down unit or the ward?
- |||||||||| Anesthetic Induction For Pyloric Stenosis. A Functioning Peripheral Intravenous Catheter: Olive You But Do I Need You? (South: Hall D-7) - Jul 20, 2023 - Abstract #ASA2023ASA_604;
Discuss the risks and benefits of each.You plan to induce anesthesia with propofol and rocuronium...Would you perform a spinal anesthetic?You decide to proceed with an inhalational induction with 100% Oxygen and 8% Sevoflurane. Intubation is facilitated with topical atomized lidocaine...Upon further investigation, you discover that during the operation, your resident gave morphine 0.1 mg/kgIV...The infant
- |||||||||| Peri-operative Pain Medicine In Multi-specialty Anesthesiology Practice For Patient With Long Covid Pain Syndrome (South: Hall D-7) - Jul 20, 2023 - Abstract #ASA2023ASA_64;
Patient was on duloxetine daily and used muscle relaxant only as needed to relieve muscle tightness, spasms, diffuse body, joints, neck, and back pain.4.Patient reported inadequate pain control despite various IV opioids in PACU and had to stay overnight for observation and treatment...What are the options of oral pain medicine for acute postoperative pain in addition to worsening chronic diffuse body and joints pain?Patient failed previous tramadol, acetaminophen with codeine due to nausea and constipation with marginal pain relief...Perioperative patient care needs to minimize escalating opioids doses and minimize duration of opioid therapy for acute postoperative pain. It is crucial to advise patient compliance with COVID protective measures with goals to improve clinical postoperative outcomes and reduce overall healthcare cost.
- |||||||||| metamizole / Generic mfg., lidocaine topical / Generic mfg., tramadol hydrochloride / Generic mfg.
A Simple Treatment For Pain Relief Of Envenomations By Caterpillars () - Jul 3, 2023 - Abstract #WCD2023WCD_7357;
Based on our past experience, we suggest using serial application of topical commercial anesthetics with 0.25% lidocaine and 0.25% prilocaine in order to greatly decrease or eliminate the pain, these drugs take effect in about half an hour and last for several hours. KEY MESSAGE: the method is easy to apply, does not interfere with the approach adopted for this kind of injury, and it is especially useful for children and patients whose lesion sites do not allow blockades
- |||||||||| lidocaine topical / Generic mfg., minoxidil / Generic mfg.
Regenerative Medidicne In Treating Androgenetic Alopecia () - Jul 3, 2023 - Abstract #WCD2023WCD_5863;
As for the subjective assessment of satisfaction, of the 50 patients treated, 39 were very satisfied, 6 patients were somewhat satisfied and five were unsatisfied. None of the patients reported any pain during the treatment.
- |||||||||| lidocaine topical / Generic mfg.
Periorbital rejuvenation with fractional ultrapulse carbon dioxide (CO2) laser in Asians () - Jul 3, 2023 - Abstract #WCD2023WCD_4773;
A topical eutectic mixture of 2.5% lidocaine hydrochloric acid and 2.5% prilocaine applied to the lesions under occlusion 1 hour before the laser treatment was used as a local anesthetic...The patients was very satisfied with the outcome of the treatment, and the treatment was well tolerated with no major adverse effects. KEY MESSAGE: Periorbital rejuvenation with fractional ultrapulse CO2 laser can be used effectively and safely in Asian patients with Fitzpatrick skintype III or IV
- |||||||||| 5-fluorouracil / Generic mfg.
Microneedling with derma pen along with 5-fluorouracil solution in the treatment of stable vitiligo () - Jul 3, 2023 - Abstract #WCD2023WCD_4228;
Using the derma pen and topical 5-fluorouracil solution is a comparatively fast, safe, effective and reproducible technique for the management of stable vitiligo without the need of extensive surgeries and minimal side effects, in our patient none was observed. The re-pigmentation observed is uniform.5-fluorouracil solution, derma pen and insulin syringe are easily available everywhere and the procedure does not need much expertise or expense, providing a clinically as well cost effective treatment modality to the patient.
- |||||||||| lidocaine topical / Generic mfg., mupirocin / Generic mfg.
Full Ablative Erbium YAG laser resurfacing in the management of Pearly Penile Papules or Hirsutoid Papillomas in a Filipino patient () - Jul 3, 2023 - Abstract #WCD2023WCD_3818;
After sanitizing the area and the application of topical lidocaine with prilocaine cream for 45 minutes...Post laser care included saline compress and application of topical mupirocin ointment and aquaphor ointment...KEY MESSAGE: Erbium YAG laser resurfacing is a safe and effective treatment modality for patients with pearly penile papules. More than one session may be needed to safely and completely ablate the lesions
- |||||||||| lidocaine topical / Generic mfg.
Journal: Metamorphosis of Topical Semisolid Products-Understanding the Role of Rheological Properties in Drug Permeation under the "in Use" Condition. (Pubmed Central) - Jun 28, 2023
This was believed to be the result of increasing viscosity and crystallization of lidocaine instead of depletion of API from the applied dose, which was confirmed by formulation F2 with a higher content of API (5% lidocaine) showing a similar pattern, i.e., a 49.7% reduction of permeability after 4 h of study. To the best of our knowledge, this is the first study to simultaneously demonstrate the rheological change of a topical semisolid formulation during volatile solvent evaporation, resulting in a concurrent decrease in the permeability of API, which provides mathematical modelers with the necessary background to build complex models that incorporate evaporation, viscosity, and drug permeation in the simulation once at a time.
- |||||||||| lidocaine topical / Generic mfg.
Trial completion: Action of Intra-auricular Topical Lidocaine on Tinnitus (clinicaltrials.gov) - Jun 27, 2023
P=N/A, N=32, Completed,
To the best of our knowledge, this is the first study to simultaneously demonstrate the rheological change of a topical semisolid formulation during volatile solvent evaporation, resulting in a concurrent decrease in the permeability of API, which provides mathematical modelers with the necessary background to build complex models that incorporate evaporation, viscosity, and drug permeation in the simulation once at a time. Active, not recruiting --> Completed
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