lidocaine topical / Generic mfg. 
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  • ||||||||||  LidoPain (lidocaine) / Immune Pharma
    Clinical, Journal:  Is burning mouth syndrome a neuropathic pain condition? (Pubmed Central) -  Apr 3, 2019   
    The central type does not respond to local treatments and associates often with psychiatric comorbidity (depression or anxiety), whereas the peripheral type responds to peripheral lidocaine blocks and topical clonazepam. Burning mouth syndrome is most prevalent in postmenopausal women, having led to a hypothesis that BMS is triggered as a consequence of nervous system damage caused by neurotoxic factors affecting especially vulnerable small fibers and basal ganglia in a setting of decrease in neuroprotective gonadal hormones and increase in stress hormone levels, typical for menopause.
  • ||||||||||  Avastin (bevacizumab) / Roche, Lucentis (ranibizumab) / Roche, Novartis
    Journal:  Lid splinting eyelid retraction technique: a minimised sterile approach for intravitreal injections. (Pubmed Central) -  Mar 29, 2019   
    This is beneficial for both the physician and the patient as it minimises patient discomfort as well as the duration of the procedure. To our knowledge, this is one of the largest studies performed to date evaluating intravitreal injection-related endophthalmitis.
  • ||||||||||  LidoPain (lidocaine) / Immune Pharma
    Preclinical, Journal:  Menthol reduces phototoxicity pain in a mouse model of photodynamic therapy. (Pubmed Central) -  Mar 23, 2019   
    ...Inhibition of fatty acid amide hydrolase, selective antagonism of TRPV1 or the application of lidocaine or its quaternary derivative QX-314, reduced AP frequency, whereas antagonism of TRPA1 had no effect...Menthol inhibited phototoxicity-evoked APs and reduced pain behavior when applied topically to mice. These findings suggest that menthol might provide pain relief in patients experiencing PpIX-phototoxicity pain caused by photodynamic therapy or erythropoietic protoporphyria.
  • ||||||||||  lidocaine topical / Generic mfg.
    Trial completion date, Trial primary completion date:  Comparison of Two Induction Regimens Using Topical Lidocaine or Muscle Relaxant on Sore Throat and Hemodynamics (clinicaltrials.gov) -  Mar 13, 2019   
    P4,  N=100, Recruiting, 
    These findings suggest that menthol might provide pain relief in patients experiencing PpIX-phototoxicity pain caused by photodynamic therapy or erythropoietic protoporphyria. Trial completion date: Jun 2019 --> Dec 2020 | Trial primary completion date: Dec 2018 --> Dec 2020
  • ||||||||||  lidocaine topical / Generic mfg.
    Trial initiation date:  Occipital Blocks for Acute Migraine (clinicaltrials.gov) -  Feb 6, 2019   
    P3,  N=58, Not yet recruiting, 
    No abstract available Initiation date: Jan 2019 --> Apr 2019
  • ||||||||||  NN1213 / Novo Nordisk
    Enrollment change, Trial completion date, Trial initiation date, Trial termination, Trial primary completion date, Surgery:  Optimal Method for Mydriasis in Cataract Surgery (clinicaltrials.gov) -  Jan 11, 2019   
    P=N/A,  N=3, Terminated, 
    Trial completion date: Dec 2018 --> Dec 2019 | Trial primary completion date: Sep 2018 --> Sep 2019 N=210 --> 3 | Trial completion date: Aug 2019 --> Aug 2018 | Initiation date: Dec 2016 --> Sep 2016 | Recruiting --> Terminated | Trial primary completion date: May 2019 --> Aug 2018; insufficient patient recruitment
  • ||||||||||  lidocaine topical / Generic mfg., nitroglycerin / Generic mfg.
    Trial completion date, Trial primary completion date:  TNT-RASP: Topical Nitroglycerine Treatment for Radial Artery Spasm Prevention (clinicaltrials.gov) -  Jan 8, 2019   
    P4,  N=300, Recruiting, 
    N=210 --> 3 | Trial completion date: Aug 2019 --> Aug 2018 | Initiation date: Dec 2016 --> Sep 2016 | Recruiting --> Terminated | Trial primary completion date: May 2019 --> Aug 2018; insufficient patient recruitment Trial completion date: Dec 2018 --> Jun 2019 | Trial primary completion date: Jun 2018 --> Jun 2019
  • ||||||||||  Emla-cream / Akorn, AstraZeneca
    Enrollment open, Biopsy:  Pain Perception During Vulvar Biopsy (clinicaltrials.gov) -  Oct 22, 2018   
    P4,  N=120, Recruiting, 
    Enrolling by invitation --> Completed Not yet recruiting --> Recruiting
  • ||||||||||  lidocaine topical / Generic mfg.
    Trial completion, Trial completion date, Trial primary completion date:  A Study of the Use of Microneedle Patches to Deliver Topical Lidocaine in the Oral Cavity (clinicaltrials.gov) -  Sep 20, 2018   
    P1,  N=16, Completed, 
    Not yet recruiting --> Recruiting Recruiting --> Completed | Trial completion date: Dec 2018 --> Aug 2018 | Trial primary completion date: Dec 2018 --> Aug 2018
  • ||||||||||  lidocaine topical / Generic mfg.
    Phase classification, Enrollment change, Trial primary completion date:  Study to Compare the Efficacy of Cognitive-behavioral Couple Therapy and Lidocaine for Provoked Vestibulodynia (clinicaltrials.gov) -  Sep 13, 2018   
    P=N/A,  N=108, Active, not recruiting, 
    Recruiting --> Completed | Trial completion date: Dec 2018 --> Aug 2018 | Trial primary completion date: Dec 2018 --> Aug 2018 Phase classification: P4 --> P=N/A | N=224 --> 108 | Trial primary completion date: Jul 2018 --> Mar 2018
  • ||||||||||  Emla-cream / Akorn, AstraZeneca
    New P4 trial, Biopsy:  Pain Perception During Vulvar Biopsy (clinicaltrials.gov) -  Aug 31, 2018   
    P4,  N=120, Not yet recruiting, 
  • ||||||||||  meloxicam / Generic mfg., lidocaine topical / Generic mfg.
    Trial completion, Trial completion date:  Lidocaine-prilocaine Cream Versus Rectal Meloxicam on Relief of Post-episiotomy Pain (clinicaltrials.gov) -  Aug 3, 2018   
    P3,  N=190, Completed, 
    Phase classification: P4 --> P=N/A | N=224 --> 108 | Trial primary completion date: Jul 2018 --> Mar 2018 Recruiting --> Completed | Trial completion date: Oct 2018 --> Jul 2018
  • ||||||||||  meloxicam / Generic mfg., lidocaine topical / Generic mfg.
    Trial completion date, Trial primary completion date:  Lidocaine-prilocaine Cream Versus Rectal Meloxicam on Relief of Post-episiotomy Pain (clinicaltrials.gov) -  Jun 27, 2018   
    P3,  N=190, Recruiting, 
    Recruiting --> Completed | Trial completion date: Oct 2018 --> Jul 2018 Trial completion date: Feb 2018 --> Oct 2018 | Trial primary completion date: Dec 2017 --> Aug 2018
  • ||||||||||  lidocaine topical / Generic mfg.
    New P3 trial:  Occipital Blocks for Acute Migraine (clinicaltrials.gov) -  May 18, 2018   
    P3,  N=58, Not yet recruiting, 
  • ||||||||||  Pliaglis (lidocaine and tetracaine topical cream 7%/7%) / Galderma
    Trial completion date, Trial primary completion date:  The Effect of Topical Anesthetics on Patients' Pain and Operative Experience During Treatment With QSwitched Laser (clinicaltrials.gov) -  Apr 26, 2018   
    P=N/A,  N=48, Active, not recruiting, 
    Trial completion date: Feb 2018 --> Oct 2018 | Trial primary completion date: Dec 2017 --> Aug 2018 Trial completion date: Mar 2018 --> Dec 2018 | Trial primary completion date: Mar 2018 --> Dec 2018
  • ||||||||||  lidocaine topical / Generic mfg.
    New P4 trial:  Post-Op Lidocaine Patch (clinicaltrials.gov) -  Apr 18, 2018   
    P4,  N=50, Recruiting, 
  • ||||||||||  lidocaine topical / Generic mfg.
    Enrollment open, Trial initiation date:  Pharmacokinetics of Lidocaine in Healthy Adults (clinicaltrials.gov) -  Mar 21, 2018   
    P4,  N=24, Recruiting, 
    Not yet recruiting --> Recruiting | Initiation date: Oct 2017 --> Mar 2018 Not yet recruiting --> Recruiting | Initiation date: Nov 2017 --> Mar 2018
  • ||||||||||  lidocaine topical / Generic mfg.
    Enrollment open:  Lidocaine for Pain After Urodynamic Testing (clinicaltrials.gov) -  Mar 14, 2018   
    P4,  N=128, Recruiting, 
    Not yet recruiting --> Recruiting | Initiation date: Nov 2017 --> Mar 2018 Not yet recruiting --> Recruiting
  • ||||||||||  Pliaglis (lidocaine and tetracaine topical cream 7%/7%) / Galderma
    Trial completion date, Trial primary completion date:  The Effect of Topical Anesthetics on Patients' Pain and Operative Experience During Treatment With QSwitched Laser (clinicaltrials.gov) -  Mar 3, 2018   
    P=N/A,  N=48, Active, not recruiting, 
    Not yet recruiting --> Recruiting | Trial completion date: Dec 2017 --> Jun 2019 | Trial primary completion date: Dec 2017 --> Dec 2018 Trial completion date: Jan 2018 --> Mar 2018 | Trial primary completion date: Jan 2018 --> Mar 2018
  • ||||||||||  lidocaine topical / Generic mfg.
    Enrollment closed, Trial completion date, Trial primary completion date:  Pain Relief for Birth Control Implants Insertion (clinicaltrials.gov) -  Feb 27, 2018   
    P3,  N=144, Active, not recruiting, 
    Recruiting --> Completed | Trial completion date: Jan 2018 --> Jan 2018 Recruiting --> Active, not recruiting | Trial primary completion date: Sep 2017 --> Sep 2018 | Trial completion date: Sep 2017 --> Sep 2018
  • ||||||||||  lidocaine topical / Generic mfg., nitroglycerin / Generic mfg.
    Trial primary completion date:  TNT-RASP: Topical Nitroglycerine Treatment for Radial Artery Spasm Prevention (clinicaltrials.gov) -  Jan 9, 2018   
    P4,  N=300, Recruiting, 
    Recruiting --> Active, not recruiting | Trial primary completion date: Sep 2017 --> Sep 2018 | Trial completion date: Sep 2017 --> Sep 2018 Trial primary completion date: Jun 2017 --> Jun 2018
  • ||||||||||  lidocaine topical / Generic mfg.
    New P4 trial:  Lidocaine for Pain After Urodynamic Testing (clinicaltrials.gov) -  Jan 8, 2018   
    P4,  N=128, Not yet recruiting, 
  • ||||||||||  lidocaine topical / Generic mfg., cyclopentolate hydrochloride / Generic mfg., epinephrine / Generic mfg.
    Trial primary completion date, Surgery:  Optimal Method for Mydriasis in Cataract Surgery (clinicaltrials.gov) -  Dec 26, 2017   
    P=N/A,  N=210, Recruiting, 
    Not yet recruiting --> Recruiting | Trial primary completion date: Mar 2018 --> Sep 2018 Trial primary completion date: May 2017 --> May 2019
  • ||||||||||  lidocaine topical / Generic mfg.
    Trial completion, Phase classification, Trial primary completion date:  Pain Relief During Repair of Postpartum Perineal Tears (clinicaltrials.gov) -  Dec 13, 2017   
    P4,  N=144, Completed, 
    Trial primary completion date: May 2017 --> May 2019 Recruiting --> Completed | Phase classification: P2/3 --> P4 | Trial primary completion date: Dec 2017 --> May 2017
  • ||||||||||  lidocaine topical / Generic mfg.
    Trial primary completion date:  Pain Relief During Repair of Postpartum Perineal Tears (clinicaltrials.gov) -  Nov 14, 2017   
    P2/3,  N=144, Recruiting, 
    Recruiting --> Completed | Phase classification: P2/3 --> P4 | Trial primary completion date: Dec 2017 --> May 2017 Trial primary completion date: Sep 2017 --> Dec 2017