- |||||||||| LidoPain (lidocaine) / Immune Pharma
Clinical, Journal: Is burning mouth syndrome a neuropathic pain condition? (Pubmed Central) - Apr 3, 2019 The central type does not respond to local treatments and associates often with psychiatric comorbidity (depression or anxiety), whereas the peripheral type responds to peripheral lidocaine blocks and topical clonazepam. Burning mouth syndrome is most prevalent in postmenopausal women, having led to a hypothesis that BMS is triggered as a consequence of nervous system damage caused by neurotoxic factors affecting especially vulnerable small fibers and basal ganglia in a setting of decrease in neuroprotective gonadal hormones and increase in stress hormone levels, typical for menopause.
- |||||||||| LidoPain (lidocaine) / Immune Pharma
Preclinical, Journal: Menthol reduces phototoxicity pain in a mouse model of photodynamic therapy. (Pubmed Central) - Mar 23, 2019 ...Inhibition of fatty acid amide hydrolase, selective antagonism of TRPV1 or the application of lidocaine or its quaternary derivative QX-314, reduced AP frequency, whereas antagonism of TRPA1 had no effect...Menthol inhibited phototoxicity-evoked APs and reduced pain behavior when applied topically to mice. These findings suggest that menthol might provide pain relief in patients experiencing PpIX-phototoxicity pain caused by photodynamic therapy or erythropoietic protoporphyria.
- |||||||||| lidocaine topical / Generic mfg.
Trial initiation date: Occipital Blocks for Acute Migraine (clinicaltrials.gov) - Feb 6, 2019 P3, N=58, Not yet recruiting, No abstract available Initiation date: Jan 2019 --> Apr 2019
- |||||||||| NN1213 / Novo Nordisk
Enrollment change, Trial completion date, Trial initiation date, Trial termination, Trial primary completion date, Surgery: Optimal Method for Mydriasis in Cataract Surgery (clinicaltrials.gov) - Jan 11, 2019 P=N/A, N=3, Terminated, Trial completion date: Dec 2018 --> Dec 2019 | Trial primary completion date: Sep 2018 --> Sep 2019 N=210 --> 3 | Trial completion date: Aug 2019 --> Aug 2018 | Initiation date: Dec 2016 --> Sep 2016 | Recruiting --> Terminated | Trial primary completion date: May 2019 --> Aug 2018; insufficient patient recruitment
- |||||||||| lidocaine topical / Generic mfg., nitroglycerin / Generic mfg.
Trial completion date, Trial primary completion date: TNT-RASP: Topical Nitroglycerine Treatment for Radial Artery Spasm Prevention (clinicaltrials.gov) - Jan 8, 2019 P4, N=300, Recruiting, N=210 --> 3 | Trial completion date: Aug 2019 --> Aug 2018 | Initiation date: Dec 2016 --> Sep 2016 | Recruiting --> Terminated | Trial primary completion date: May 2019 --> Aug 2018; insufficient patient recruitment Trial completion date: Dec 2018 --> Jun 2019 | Trial primary completion date: Jun 2018 --> Jun 2019
- |||||||||| Emla-cream / Akorn, AstraZeneca
Enrollment open, Biopsy: Pain Perception During Vulvar Biopsy (clinicaltrials.gov) - Oct 22, 2018 P4, N=120, Recruiting, Enrolling by invitation --> Completed Not yet recruiting --> Recruiting
- |||||||||| meloxicam / Generic mfg., lidocaine topical / Generic mfg.
Trial completion, Trial completion date: Lidocaine-prilocaine Cream Versus Rectal Meloxicam on Relief of Post-episiotomy Pain (clinicaltrials.gov) - Aug 3, 2018 P3, N=190, Completed, Phase classification: P4 --> P=N/A | N=224 --> 108 | Trial primary completion date: Jul 2018 --> Mar 2018 Recruiting --> Completed | Trial completion date: Oct 2018 --> Jul 2018
- |||||||||| meloxicam / Generic mfg., lidocaine topical / Generic mfg.
Trial completion date, Trial primary completion date: Lidocaine-prilocaine Cream Versus Rectal Meloxicam on Relief of Post-episiotomy Pain (clinicaltrials.gov) - Jun 27, 2018 P3, N=190, Recruiting, Recruiting --> Completed | Trial completion date: Oct 2018 --> Jul 2018 Trial completion date: Feb 2018 --> Oct 2018 | Trial primary completion date: Dec 2017 --> Aug 2018
- |||||||||| lidocaine topical / Generic mfg.
New P4 trial: Post-Op Lidocaine Patch (clinicaltrials.gov) - Apr 18, 2018 P4, N=50, Recruiting,
- |||||||||| lidocaine topical / Generic mfg.
Enrollment open, Trial initiation date: Pharmacokinetics of Lidocaine in Healthy Adults (clinicaltrials.gov) - Mar 21, 2018 P4, N=24, Recruiting, Not yet recruiting --> Recruiting | Initiation date: Oct 2017 --> Mar 2018 Not yet recruiting --> Recruiting | Initiation date: Nov 2017 --> Mar 2018
- |||||||||| lidocaine topical / Generic mfg.
Enrollment open: Lidocaine for Pain After Urodynamic Testing (clinicaltrials.gov) - Mar 14, 2018 P4, N=128, Recruiting, Not yet recruiting --> Recruiting | Initiation date: Nov 2017 --> Mar 2018 Not yet recruiting --> Recruiting
- |||||||||| lidocaine topical / Generic mfg.
Enrollment closed, Trial completion date, Trial primary completion date: Pain Relief for Birth Control Implants Insertion (clinicaltrials.gov) - Feb 27, 2018 P3, N=144, Active, not recruiting, Recruiting --> Completed | Trial completion date: Jan 2018 --> Jan 2018 Recruiting --> Active, not recruiting | Trial primary completion date: Sep 2017 --> Sep 2018 | Trial completion date: Sep 2017 --> Sep 2018
- |||||||||| lidocaine topical / Generic mfg., nitroglycerin / Generic mfg.
Trial primary completion date: TNT-RASP: Topical Nitroglycerine Treatment for Radial Artery Spasm Prevention (clinicaltrials.gov) - Jan 9, 2018 P4, N=300, Recruiting, Recruiting --> Active, not recruiting | Trial primary completion date: Sep 2017 --> Sep 2018 | Trial completion date: Sep 2017 --> Sep 2018 Trial primary completion date: Jun 2017 --> Jun 2018
- |||||||||| lidocaine topical / Generic mfg., cyclopentolate hydrochloride / Generic mfg., epinephrine / Generic mfg.
Trial primary completion date, Surgery: Optimal Method for Mydriasis in Cataract Surgery (clinicaltrials.gov) - Dec 26, 2017 P=N/A, N=210, Recruiting, Not yet recruiting --> Recruiting | Trial primary completion date: Mar 2018 --> Sep 2018 Trial primary completion date: May 2017 --> May 2019
- |||||||||| lidocaine topical / Generic mfg.
Trial completion, Phase classification, Trial primary completion date: Pain Relief During Repair of Postpartum Perineal Tears (clinicaltrials.gov) - Dec 13, 2017 P4, N=144, Completed, Trial primary completion date: May 2017 --> May 2019 Recruiting --> Completed | Phase classification: P2/3 --> P4 | Trial primary completion date: Dec 2017 --> May 2017
- |||||||||| lidocaine topical / Generic mfg.
Trial primary completion date: Pain Relief During Repair of Postpartum Perineal Tears (clinicaltrials.gov) - Nov 14, 2017 P2/3, N=144, Recruiting, Recruiting --> Completed | Phase classification: P2/3 --> P4 | Trial primary completion date: Dec 2017 --> May 2017 Trial primary completion date: Sep 2017 --> Dec 2017
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