lidocaine topical / Generic mfg. 
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  • ||||||||||  midazolam hydrochloride / Generic mfg.
    Mucopolysaccharidosis type IIIA - anesthesia approach, a case report ([VIRTUAL]) -  Nov 25, 2021 - Abstract #Euroanaesthesia2021Euroanaesthesia_1222;    
    The patient was sedated using 0,5 MAC of sevoflurane and 1 mcg/kg of fentanyl...After confirmation of a secure airway, induction of general anesthesia, guided by Bispectral index and neuromuscular blockade was performed using rocuronium...Preferably, a full diagnosis and comorbidities optimization should occur before an elective procedure. Early recognition of difficult airway allowing for timely planning and management is crucial for patient safety.Learning points: Difficult airway management has been reported so planning and preparation for all possible scenarios is important to assure the safety of our patients.
  • ||||||||||  dexamethasone / Generic mfg., pregabalin / Generic mfg.
    Chronic postoperative inguinal pain: a stepwise approach for pain control ([VIRTUAL]) -  Nov 25, 2021 - Abstract #Euroanaesthesia2021Euroanaesthesia_1181;    
    Pregabalin, topical capsaicin and metamizole SOS was started...Evolution to pulsed radiofrequency (pRF) (38º, 120 sec) of nerve II at the right and left (1st - 1 cycle; 8 months interval; 2nd - 2 cycles; 4 months interval; 3rd - 2 cycles), under ultrasound control, with administration of lidocaine 2% 3mL, ropivacaine 0.2% 10mL and dexamethasone 4mg...Learning points: Invasive techniques for the control of CPIP must be part of the therapeutic weapons available to each patient. A diagnostic and therapeutic approach at levels of increasing complexity / risk must be followed.
  • ||||||||||  fentanyl citrate / Generic mfg., sevoflurane / Generic mfg., lidocaine topical / Generic mfg.
    Anaesthetic management in Apert’s Syndrome ([VIRTUAL]) -  Nov 25, 2021 - Abstract #Euroanaesthesia2021Euroanaesthesia_1099;    
    C-MAC videolaryngoscopy showed partially closed vocal cords; lidocaine 30mg was administered topically, allowing for subsequent insertion of 6mm endotracheal tube...Regional anesthesia is recommended. General anesthesia is an option when difficult airway management equipment is available.
  • ||||||||||  lidocaine topical / Generic mfg.
    Journal:  Oxygen desaturation and time burden during tracheobronchial endoscopy for suspected foreign body in toddlers. (Pubmed Central) -  Nov 21, 2021   
    Initial admission to general hospitals (OR 0.23, 95% CI 0.06-0.86) and airway anaesthesia with topical lidocaine (OR 0.15, 95% CI 0.03-0.62) were associated with a reduced risk of high hypoxic burden...No postoperative neurological sequelae were found. The hypoxic burden approach, when applied in tracheobronchial endoscopy for suspected foreign body aspiration in toddlers, enabled the quantification of hypoxemia and the search for specific risk factors.
  • ||||||||||  lidocaine topical / Generic mfg.
    Journal:  Comparing Vestibule Examination Techniques: Light Touch, Serial Forces, and the Lidocaine Test. (Pubmed Central) -  Nov 21, 2021   
    Light rolling cotton swab touch using the 4-item verbal scale can map vestibulodynia tenderness that can be extinguished by lidocaine, consistent with distinguishing a mucosal condition. Forces by vulvalgesiometer of greater than 100-200 g may evoke pain other than mucosal allodynia.
  • ||||||||||  lidocaine topical / Generic mfg., prochlorperazine maleate / Generic mfg.
    Trial completion date, Trial primary completion date:  SPG Block for Acute Pediatric Migraine (clinicaltrials.gov) -  Nov 17, 2021   
    P3,  N=72, Recruiting, 
    Perianal application for 10 min seems to be optimal. Trial completion date: Dec 2021 --> Dec 2022 | Trial primary completion date: Jun 2021 --> Jun 2022
  • ||||||||||  lidocaine topical / Generic mfg., clonidine / Generic mfg.
    Review, Journal:  Novel treatment modalities for painful diabetic neuropathy. (Pubmed Central) -  Nov 7, 2021   
    Novel MONRI, SNRI and cannabinoid receptor agonists have shown some promise for neuropathic pain relief in human trials, but await regulatory approvals. However, most of the novel pharmacological agents (systemic or topical) require appropriately powered placebo-controlled studies for clinical usage in painful diabetic neuropathy.
  • ||||||||||  lidocaine topical / Generic mfg.
    Review, Journal:  A Substantive Narrative Review on the Usage of Lidocaine in Cataract Surgery. (Pubmed Central) -  Nov 7, 2021   
    Perhaps this standard could change over time as it is generally known that using intracameral injections in conjunction with topical anesthesia produces better patient outcomes. The authors find that although anesthetics and surgical treatment for cataracts are generally beneficial for patients, there are still many adjustments that could be implemented to enhance patient outcomes.
  • ||||||||||  ketamine / Generic mfg.
    Awake fibreoptic intubation in a difficult airway with tracheal stenosis – is “Ketodex” a player? ([VIRTUAL]) -  Oct 31, 2021 - Abstract #Euroanaesthesia2021Euroanaesthesia_806;    
    Many sedation regimens for AFOI including combination of dexmedetomidine and ketamine infusions (“Ketodex”) have been published...Upper airway topicalization was achieved with 2% lidocaine...Learning points: Ketodex plus topical anaesthesia provided good conditions for AFOI with minimal side effects making it a safe and effective strategy in patients with difficult airway predictors. Further studies are needed to support this hypothesis and identify the best dosage regimen.
  • ||||||||||  lidocaine topical / Generic mfg.
    Lidocaine patch for localized neuropathic pain: a single center audit. ([VIRTUAL]) -  Oct 31, 2021 - Abstract #Euroanaesthesia2021Euroanaesthesia_757;    
    There were no serious adverse events. This retrospective study demonstrated that a topical the Versatis patch can be considered for patients with peripheral neuropathic pain.
  • ||||||||||  lidocaine topical / Generic mfg.
    Awake fiberoptic intubation in Morbihan syndrome: a case report ([VIRTUAL]) -  Oct 31, 2021 - Abstract #Euroanaesthesia2021Euroanaesthesia_694;    
    Following adequate Covid-19 precautions and standard monitoring, topical anesthesia with 10% lidocaine was performed for upper airway and combined with spray-asyou-go technique for vocal cords...Alternative plans for failure of ATI should be discussed with the whole team before starting (2). MS patients with expected difficult airway can be a striking example of inevitable ATI requirement during covid-19.
  • ||||||||||  lidocaine topical / Generic mfg.
    Review, Journal:  Comprehensive Review of Topical Analgesics for Chronic Pain. (Pubmed Central) -  Oct 27, 2021   
    Topical analgesics are a relatively benign treatment for chronic pain conditions including neuropathic pain, musculoskeletal, and myofascial pain. There is evidence to support the use of topical NSAIDs, high concentration topical capsaicin, and topical lidocaine for various painful conditions.
  • ||||||||||  lidocaine topical / Generic mfg.
    Journal:  Effect of sensory blockade and rate of sensory stimulation on local heating induced axon reflex response in facial skin. (Pubmed Central) -  Oct 27, 2021   
    We assessed CVC during fast (1 °C/30s) and slow (1 °C/10 min) local heating to 43 °C in both NaV inhibition (topical 2.5% lidocaine/prilocaine) and control conditions...Slower sensory afferent activation rate eliminated the axon reflex response in facial and non-glabrous skin, but topical sensory blockade did not block axon reflex responses in flushing-prone cheek skin. Thus, slower heating protocols are needed to abate facial, particularly cheek, axon reflex responses.
  • ||||||||||  lidocaine topical / Generic mfg.
    Clinical, Journal:  Efficacy of Intra-Operative Topical Wound Anaesthesia to Mitigate Piglet Castration Pain-A Large, Multi-Centred Field Trial. (Pubmed Central) -  Oct 25, 2021   
    There was a significant reduction in nociceptive motor and vocal response during castration and in the post-operative pain-related behaviour response in Tri-Solfen-treated compared to untreated piglets, in the first 30 min following castration. Although not addressing pain of skin incision, Tri-Solfen is effective to mitigate subsequent acute castration-related pain in piglets under commercial production conditions.
  • ||||||||||  lidocaine topical / Generic mfg., docetaxel / Generic mfg.
    Journal:  Docetaxel and Lidocaine Co-Loaded (NLC-in-Hydrogel) Hybrid System Designed for the Treatment of Melanoma. (Pubmed Central) -  Oct 25, 2021   
    No adverse effects were observed in cell survival, weight/feed-consumption or serum biochemical markers (ALT, AST, creatinine, urea) of animals treated with NLC or the hybrid system. These results confirm the adjuvant antitumor effect of lidocaine and endorse HGel-NLC-LDC as a promising formulation for the topical treatment of melanoma.
  • ||||||||||  lidocaine topical / Generic mfg.
    Trial initiation date, Trial primary completion date:  Inhibition of Non-histaminergic Pruritus Applied Using 3 Different Pruritogens (clinicaltrials.gov) -  Oct 15, 2021   
    P=N/A,  N=22, Not yet recruiting, 
    Continued efforts must be made to find means to relieve pain by using simple, effective analgesia or adjusting the technique, and not using a tenaculum whenever possible. Initiation date: Sep 2021 --> Dec 2021 | Trial primary completion date: Oct 2021 --> May 2022
  • ||||||||||  dapsone / Generic mfg., lidocaine topical / Generic mfg.
    [VIRTUAL] A RARE CASE OF IDIOPATHIC METHEMOGLOBINEMIA () -  Oct 13, 2021 - Abstract #CHEST2021CHEST_490;    
    Multiple agents have been associated with acquired methemoglobinemia including dapsone, topical anesthetics, and inhaled nitric oxide...There are case reports for methemoglobinemia associated with topical anesthetics in the literature, but what is unique about our patient is the previous exposure to lidocaine without any complications which is not typically seen in acquired methemoglobinemia. Methemoglobinemia should be considered in patients with cyanosis and discordant oxygen saturation and PaO2 results.
  • ||||||||||  lidocaine topical / Generic mfg.
    Clinical, Observational data, Journal:  Cross-sectional study of pediatric pain prevalence, assessment, and treatment at a Canadian tertiary hospital. (Pubmed Central) -  Oct 8, 2021   
    A total 29% (6/21) of infants with heel lance or injection received breastfeeding or sucrose, and 29% (7/24) of participants receiving other needle procedures had documented or reported topical lidocaine use...An institution-wide quality improvement approach is required to address pain care. Pain assessment and needle pain prevention and treatment should be prioritized in these pediatric acute care and newborn care settings.
  • ||||||||||  ketamine / Generic mfg.
    Awake Fiberoptic Intubation In A Patient With A Large Obstructing Tongue Mass (Exhibit Hall) -  Sep 25, 2021 - Abstract #ASA2021ASA_4645;    
    Ketamine was administered followed by fiberoptic bronchoscope insertion through an ovassapian airway...Propofol and succinylcholine were bolused, and upon resolution of laryngospasm, the bronchoscope was advanced. A 7.0mm endotracheal tube was placed and confirmed with capnography.
  • ||||||||||  lidocaine topical / Generic mfg.
    Unanticipated Finding Of Posterior Laryngeal Web During Stat Intubation - Preparation And Management (Exhibit Hall) -  Sep 25, 2021 - Abstract #ASA2021ASA_4617;    
    Inability to advance the ETT over the scope led to concurrent Glidescope use demonstrating a posterior laryngeal web previously unseen, presumed secondary to a previous traumatic intubation. A 5.0 mm microlaryngeal ETT was successfully placed with subsequent web excision and tracheostomy.
  • ||||||||||  midazolam hydrochloride / Generic mfg.
    Airway Management In A Patient With Submassive Hemoptysis (Exhibit Hall) -  Sep 25, 2021 - Abstract #ASA2021ASA_4270;    
    Awake fiberoptic intubation successfully performed utilizing glycopyrrolate, dexmedetomidine, and midazolam with topical lidocaine. Bronchoscopy was unable to identify a clear source lesion.