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Clinical, Journal: Discovery of LY3325656: A GPR142 agonist suitable for clinical testing in human. (Pubmed Central) - Apr 22, 2021 These led to the identification of compound 21 (LY3325656), which demonstrated anti-diabetic benefits in pre-clinical studies and ADME/PK properties suitable for human dosing. Compound 21 is the first GPR142 agonist molecule advancing to phase 1 clinic trials for the treatment of Type 2 diabetes.
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