MEDI5083 / AstraZeneca 
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  • ||||||||||  Imjudo (tremelimumab) / AstraZeneca, Pfizer, MEDI5083 / AstraZeneca, Imfinzi (durvalumab) / AstraZeneca
    Trial completion date, Trial primary completion date, Combination therapy, Metastases:  MEDI5083 Alone and in Combination With Durvalumab, Tremelimumab, and/or Docetaxel. (clinicaltrials.gov) -  Feb 17, 2020   
    P1,  N=38, Active, not recruiting, 
    In vivo, this translates to enhanced control of both poorly- and well-infiltrated syngeneic tumors and generation of durable memory in mice with complete tumor regression. Trial completion date: Jan 2020 --> May 2020 | Trial primary completion date: Jan 2020 --> May 2020
  • ||||||||||  Imjudo (tremelimumab) / AstraZeneca, Pfizer, MEDI5083 / AstraZeneca, Imfinzi (durvalumab) / AstraZeneca
    Enrollment change, Trial completion date, Trial primary completion date, Combination therapy, Metastases:  MEDI5083 Alone and in Combination With Durvalumab, Tremelimumab, and/or Docetaxel. (clinicaltrials.gov) -  Aug 8, 2019   
    P1,  N=38, Active, not recruiting, 
    The toxicity profile does not support further development of the subcutaneous formulation of this drug. N=495 --> 38 | Trial completion date: Aug 2022 --> Dec 2019 | Trial primary completion date: Aug 2022 --> Dec 2019
  • ||||||||||  Imjudo (tremelimumab) / AstraZeneca, Pfizer, MEDI5083 / AstraZeneca, Imfinzi (durvalumab) / AstraZeneca
    Enrollment closed, Enrollment change, Combination therapy, Metastases:  MEDI5083 Alone and in Combination With Durvalumab, Tremelimumab, and/or Docetaxel. (clinicaltrials.gov) -  May 13, 2019   
    P1,  N=495, Active, not recruiting, 
    N=495 --> 38 | Trial completion date: Aug 2022 --> Dec 2019 | Trial primary completion date: Aug 2022 --> Dec 2019 Recruiting --> Active, not recruiting | N=204 --> 495
  • ||||||||||  Imjudo (tremelimumab) / AstraZeneca, Pfizer, MEDI5083 / AstraZeneca, Imfinzi (durvalumab) / AstraZeneca
    Enrollment open, Combination therapy, Metastases:  MEDI5083 Alone and in Combination With Durvalumab, Tremelimumab, and/or Docetaxel. (clinicaltrials.gov) -  Apr 22, 2017   
    P1,  N=204, Recruiting, 
    Recruiting --> Active, not recruiting | N=204 --> 495 Not yet recruiting --> Recruiting