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/
Generic mfg.
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26 Diseases
6 Trials
6 Trials
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Vascepa
(icosapent ethyl) /
Amarin
1 every 3 #JPM20 attendees suffer TG levels ≥150 mg/dL . Should attend $AMRN conference , could benefit form Vascepa.
(Twitter) - Dec 18, 2019
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Vascepa
(icosapent ethyl) /
Amarin
Big win for Vascepa! https://t.co/8RgUgkeo2E via @medscape
(Twitter) - Dec 17, 2019
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Zetia as well. You said she does not want to take a statin? Better NNT w Vascepa vs repatha but not a direct comparison. I can usually get LDL down to 30 w high fiber diet and low dose Crestor even weekly
(Twitter) - Dec 17, 2019
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Vascepa
(icosapent ethyl) /
Amarin
.We knew Vascepa works with little or no statin on board. In JELIS, meanLDL- 181, 2gms of EPA reduced CV risk by 19%. This was largely ignored by mainstream medicine. Millions untreated for > 12 years. Vascepa works at the blood vessel directly, not 1°ly by decr. triglycerides.
(Twitter) - Dec 17, 2019
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Vascepa
(icosapent ethyl) /
Amarin
Clinical:
Yes, Vascepa works. No argument there. However, the next step in the scientific understanding of the clinical benefit of omega-3s is to tackle the non-TG mechanisms and the potential unique benefit of EPA vs. other omega-3s.
(Twitter) - Dec 17, 2019
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Vascepa
(icosapent ethyl) /
Amarin
Clinical:
Just like millions will say they won't wait. It's academic now if DHA works in any proportion because V works very well and it's available now. Even if it works after a 6 year redefined trial that doesn't disprove the efficacy of Vascepa.
(Twitter) - Dec 17, 2019
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Vascepa
(icosapent ethyl) /
Amarin
Congrats to @DLBHATTMD on orchestrating a study on a drug that will undoubtedly save many people’s lives! #Vascepa @Amarincorp
(Twitter) - Dec 17, 2019
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Omtryg
(omega-3 acid ethyl esters) /
Aker Biomarine, Trygg Pharma
,
Vascepa
(icosapent ethyl) /
Amarin
,
omega-3 ethylester concentrate
/
Generic mfg.
Furthermore, if STRENGTH shows cardio benefit w/ EPA/DHA free fatty acids, then it is no stretch at all to assume that EPA/DHA ethyl esters (Omtryg, Lovaza), which are generic now, would also show benefit. The latter are cheap & many might just opt for generic over Vascepa. $AMRN
(Twitter) - Dec 17, 2019
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Vascepa
(icosapent ethyl) /
Amarin
beauty of SDM....every pt has different values, preferences and ability to afford out of pocket vary. Having both PCSK9i & Vascepa means at least 300 dollars/month OOP. for someone with no athero, my pt was having difficulty finding 'utility' in considering expensive therapies
(Twitter) - Dec 17, 2019
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Vascepa
(icosapent ethyl) /
Amarin
Clinical:
Why is she a patient? Any symptoms or just the product of routine lipid screening? If it was my mother, I’d want her on vascepa or anti-PCSK9 (even if currently athero negative, tests have zero prognostic value beyond 5yrs and she could live 25+yrs) with CCTA every 5yrs
(Twitter) - Dec 17, 2019
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Head-to-Head:
Even more informative would be to test EPA/DHA ethyl ester (Omtryg/Lovaza) head to head against EPA ethyl ester (Vascepa) at same dose in normal TG pop. If STRENGTH Epanova trial shows cardio benefit, this would be warranted.
(Twitter) - Dec 17, 2019
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Vascepa
(icosapent ethyl) /
Amarin
Clinical:
The obvious way to straighten this out is to run follow up outcomes trial w/ high dose (4g/day) Vascepa in high risk patients w/ normal TG. The current label reflects Amarin's clinical development. To expand label they need to prove efficacy in normal TG pop. @TerraPharma1
(Twitter) - Dec 17, 2019
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Vascepa
(icosapent ethyl) /
Amarin
How can this be straightened? Why should medication of this type be restrictive simply due to trial design-seems like very linear thinking. OTC omegas don't require Statin to be taken. And they are unproven unlike Vascepa.
(Twitter) - Dec 17, 2019
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Vascepa
(icosapent ethyl) /
Amarin
With FDA expanded indication for use of Vascepa how will your use be affected? PlsVT/RT @DLBHATTMD @HeartOTXHeartMD @DrMarthaGulati @iamritu @MinnowWalsh @DrToniyaSingh @ErinMichos @gina_lundberg @lipiddoc @DocSavageTJU @SharonneHayes @purviparwani @Pooh_Velagapudi #cardiotwitter
(Twitter) - Dec 17, 2019
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Vascepa
(icosapent ethyl) /
Amarin
why Vascepa? or anything else?
(Twitter) - Dec 16, 2019
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Vascepa
(icosapent ethyl) /
Amarin
High fiber diet and Vascepa
(Twitter) - Dec 16, 2019
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Vascepa
(icosapent ethyl) /
Amarin
@DLBHATTMD Some are still missing the point. 1. Triglycerides are blood markers and a number. If reduction in trigs doesn't improve CV risk then it's mute effort e.g. OTC omegas. 2. Seriously, you don't need Statin for Vascepa to work. Just that the trial posed V as an adjunct.
(Twitter) - Dec 16, 2019
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Vascepa
(icosapent ethyl) /
Amarin
Clinical:
Dr. do you have an estimation of the population in the US that #vascepa can treat?
(Twitter) - Dec 16, 2019
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Vascepa
(icosapent ethyl) /
Amarin
FDA event:
FDA approves icosapent ethyl to reduce CV risk https://t.co/SkMklBd5be
(Twitter) - Dec 16, 2019
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Vascepa
(icosapent ethyl) /
Amarin
Clinical:
FDA Expands Vascepa to Reduce Cardiovascular Events in Elevated Triglyceride Patients https://t.co/eGGkJ1EWei
(Twitter) - Dec 16, 2019
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Vascepa
(icosapent ethyl) /
Amarin
FDA event:
FDA approves omega-3 fish-oil medication Vascepa to reduce risk of death in people with high cholesterol. "I believe this is the biggest thing since statins," @DLBHATTMD prof @harvardmed @BrighamWomens. by @BlairChanceMD1 https://t.co/6DlaXqHCAY
(Twitter) - Dec 16, 2019
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Vascepa
(icosapent ethyl) /
Amarin
FDA event:
FDA approves CV event risk reduction indication for icosapent ethyl https://t.co/PjXAe4rhsA
(Twitter) - Dec 16, 2019
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Vascepa
(icosapent ethyl) /
Amarin
Clinical, FDA event:
FDA Approval of Icosapent Ethyl (Vascepa) https://t.co/SSVSf9tk3s via @drmarthagulati @WomenHeartOrg @MendedHearts @TheFHFoundation @ASPCardio @ABCardio1 @advcardiohealth @HeartNurses @NbnaInc @TheAACE @HealthyWomen @AmDiabetesAssn @mmillermd1 @ErinMichos @lipiddoc @KimPcna
(Twitter) - Dec 16, 2019
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Vascepa
(icosapent ethyl) /
Amarin
#IcosapentEthyl may act on plaque. Commentary from @ThomasMDas @DocVakil @rblument1 and @SethShayMartin https://t.co/HL66bCVLrB
(Twitter) - Dec 16, 2019
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Vascepa
(icosapent ethyl) /
Amarin
New standard of care!!! Millions will benefit, 25% lives saved. PPS is great, but saving lives is what $AMRN #Vascepa is all about. TY JT @DLBHATTMD all AMRN CREW.
(Twitter) - Dec 16, 2019
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Vascepa
(icosapent ethyl) /
Amarin
Clinical:
Questions. 1- Do you need high triglycerides or will every patient benefit from Vascepa? 2- If every patient, is the mechanism inflammation? 3- Will pure DHA also accomplish same reduction in CVS mortality? 4- Are pure forms of EPA or DHA better than the combo? 5- Is more better?
(Twitter) - Dec 16, 2019
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Vascepa
(icosapent ethyl) /
Amarin
Clinical, FDA event:
Please share my blog with your patients: Martha Moments- FDA Approval of Icosapent Ethyl (#Vascepa)- All fish oils are not created equal. @CardioSmart @DLBHATTMD @AnumSaeedMD @cshekarMD @mmamas1973 @hvanspall @cardioPCImom @mpob @HeartOTXHeartMD https://t.co/Yq69yxIE3W
(Twitter) - Dec 16, 2019
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Vascepa
(icosapent ethyl) /
Amarin
I think there are lots of us not on a statin, no cardiac event but high triglycerides and family history of heart problems and I don’t want to be like the rest of the family. $amrn. I have been on Vascepa for a year and all blood panels show it works.
(Twitter) - Dec 15, 2019
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Vascepa
(icosapent ethyl) /
Amarin
By 2029, AMRN could make Vascepa OTC or lower price to compete while bringing online vascepa 2.0. Working with Mochida on new epa products. One contender is MND-2119 or similar. Once daily, self emulsifying, greater bioavailability, not meal specific.
(Twitter) - Dec 15, 2019
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Vascepa
(icosapent ethyl) /
Amarin
Clinical:
Lifestyle is ALWAYS recommended if one lives an unhealthy one. ON TOP OF THAT, now doctors have VASCEPA to add to their recommendations.
(Twitter) - Dec 15, 2019
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Vascepa
(icosapent ethyl) /
Amarin
Clinical, FDA event:
Amarin's fish oil-based VASCEPA wins "a blockbuster approval" by FDA to lower the risks of heart attack, stroke, & CV death in patients of high triglyceride (TG) level. @US_FDA #lipids #triglycerides #heart @DLBHATTMD @LindaJ_onPharma @CBallantyneMD https://t.co/22756JEe4Z
(Twitter) - Dec 15, 2019
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Vascepa
(icosapent ethyl) /
Amarin
My goodness, if Prime Minister Modi’s team knew about Vascepa, things would likely get facilitated in a jiff. V could be transformative there, potentially impacting most Indian families in India. No joke. CVD, high TG & T2D abound, sadly, as well as premature CV death
(Twitter) - Dec 15, 2019
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Vascepa
(icosapent ethyl) /
Amarin
China has a similar program. Eddingpharm has already run their PK and ethnicity studies for Vascepa and once the MARINE-style study there completes (successfully), they *might* be able to apply to have the R-IT results allowed.
(Twitter) - Dec 15, 2019
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Vascepa
(icosapent ethyl) /
Amarin
,
Repatha
(evolocumab) /
Amgen, Astellas
Clinical:
Also, Reddy's could help speed up the registration and marketing process there. India does have a p3 clinical trial waiver for certain drugs approved elsewhere but not sure if Vascepa qualifies. Even Repatha had trouble at first. Something to keep an eye on though.
(Twitter) - Dec 15, 2019
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Vascepa
(icosapent ethyl) /
Amarin
This would be a really meaningful development in the CVD space; I would love for Vascepa to be available in India! Such a huge burden of CVD in India. A topic near and dear to my heart. Hope it happens @Amarincorp ... @alka_kanaya @PowellJose @purviparwani @iamritu
(Twitter) - Dec 14, 2019
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Vascepa
(icosapent ethyl) /
Amarin
Great coverage by @DrJAshton of the REDUCE-IT trial results which led to the FDA expanding the label for icosapent ethyl to include cardiovascular risk reduction! @gabrielsteg @mmillermd1 @CBallantyneMD @BrighamWomens
(Twitter) - Dec 14, 2019
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Vascepa
(icosapent ethyl) /
Amarin
Clinical:
One of the biggest criticism on the REDUCE It study that proved Vascepa provide 25% Cardiovascular mortality benefit was the use of minral oil placebo. Thanks @DLBHATTMD #endotwitter #medtwitter #Endocrine
(Twitter) - Dec 14, 2019
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Vascepa
(icosapent ethyl) /
Amarin
Clinical:
After showing 20% MACE risk reduction in #REDUCEIT, icosapent ethyl has been approved as an add-on CV therapy in patients on #statins. #CardioTwitter #MedTwitter @DLBHATTMD https://t.co/0R4H8XebwA
(Twitter) - Dec 14, 2019
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Vascepa
(icosapent ethyl) /
Amarin
Clinical, Reimbursement:
I would take Vascepa (or other Rx purified omega-3 mix) in a heartbeat (no pun intended). But I'm probably too healthy (no diabetes or prior CVD event, normal triglycerides) for insurance to cover. How healthy people can get insurance to cover for primary prevention? @DLBHATTMD
(Twitter) - Dec 14, 2019
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Vascepa
(icosapent ethyl) /
Amarin
HEOR:
congrats. curious if folks are looking at Vascepa's potential impact on health care cost savings from public health perspective in terms of decreased mortality and morbidity.
(Twitter) - Dec 14, 2019
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Vascepa
(icosapent ethyl) /
Amarin
FDA event:
"Nothing this significant has happened in the world of #cardiovascular prevention since the introduction of statins nearly 3 decades ago," says @DLBHATTMD on FDA approval of #CV indication for #Vascepa $AMRN https://t.co/t5TpA6YHlT via @AJMC_Journal
(Twitter) - Dec 14, 2019
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Vascepa
(icosapent ethyl) /
Amarin
Agree! Pierre🧣 @SABOURETCardio you can get the French 🇫🇷 on board with icosapent ethyl & its’ tremendous benefits
(Twitter) - Dec 14, 2019
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Vascepa
(icosapent ethyl) /
Amarin
Clinical:
Having spent a wonderful summer in Paris learning about structural intervention and cardiology in general from French physicians, I sincerely hope French patients will be able to benefit from icosapent ethyl. Perhaps you and other French leaders can make it happen. @gabrielsteg
(Twitter) - Dec 14, 2019
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Vascepa
(icosapent ethyl) /
Amarin
Yes. An important message that will need to get out to neurologists (especially stroke neurologists). A significant 28% reduction in fatal or nonfatal stroke with icosapent ethyl, as published in @NEJM : https://t.co/PIOpLnU4Fd
(Twitter) - Dec 14, 2019
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Vascepa
(icosapent ethyl) /
Amarin
Clinical:
A late-stage study showed that Vascepa can reduce the risk of cardiovascular-disease events in patients with elevated triglyceride levels who are high risk and on cholesterol-lowering drugs https://t.co/znbcqxm5oJ via @WSJ
(Twitter) - Dec 14, 2019
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Vascepa
(icosapent ethyl) /
Amarin
Clinical:
Since Vascepa benefit was observed regardless of baseline TG or change in TG, seems that best next trial to expand label even more would be to prove benefit in at risk patients with absolutely no TG requirement. @matthewherper @adamfeuerstein @DLBHATTMD @TerraPharma1 @Amarincorp
(Twitter) - Dec 14, 2019
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Vascepa
(icosapent ethyl) /
Amarin
Vascepa for everyone!!!
(Twitter) - Dec 14, 2019
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Vascepa
(icosapent ethyl) /
Amarin
FDA event:
Deepak - you are nice to say so, and I’ll say it for you as well - evidence today’s FDA approval of eicosapent ethyl!
(Twitter) - Dec 13, 2019
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Vascepa
(icosapent ethyl) /
Amarin
thanks for your diligent pursuit for Vascepa approval. I took it; noticed results 'before' recommending Amarin stock by the way (I do ingerletter. com and started financial TV years ago). I admire your work and await good results from EVAPORATE, NASH and BRAVE..maybe all help.
(Twitter) - Dec 13, 2019
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Vascepa
(icosapent ethyl) /
Amarin
Would stick with Vascepa as it’s a purified a fish-oil preparation that only contains EPA
(Twitter) - Dec 13, 2019