icosapent ethyl / Generic mfg. 
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  • ||||||||||  icosapent ethyl / Generic mfg.
    Review, Journal:  EPA's pleiotropic mechanisms of action: a narrative review. (Pubmed Central) -  Aug 13, 2021   
    Treatment with icosapent ethyl 4 g/day, a highly purified and stable ethyl ester of eicosapentaenoic acid (EPA), demonstrated a significant reduction in atherosclerotic cardiovascular disease (ASCVD) events and death in REDUCE-IT...Clinically, this may translate into improved vascular health, including regression of atherosclerotic plaque. Overall, EPA has a range of pleiotropic effects that contribute to a reduction in ASCVD.
  • ||||||||||  icosapent ethyl / Generic mfg.
    Journal:  When to lower triglycerides? (Pubmed Central) -  Aug 4, 2021   
    There is evidence for the benefits of IPE in preventing ASCVD events. A novel fibrate is in clinical trials.
  • ||||||||||  icosapent ethyl / Generic mfg.
    Enrollment closed, Preclinical, Trial completion date, Trial primary completion date:  BRAVE-EPA: Brain Amyloid and Vascular Effects of Eicosapentaenoic Acid (clinicaltrials.gov) -  Jul 26, 2021   
    P2/3,  N=150, Active, not recruiting, 
    Consequently, purified EPA appears to be the treatment of choice for high-risk patients with hypertriglyceridemia. Recruiting --> Active, not recruiting | Trial completion date: Nov 2021 --> Jan 2023 | Trial primary completion date: Nov 2021 --> Jan 2023
  • ||||||||||  icosapent ethyl / Generic mfg.
    VASCEPA! (Twitter) -  Jul 24, 2021