 |
0 Diseases |  |
1 Trial |
|
1 Trial |  |
3 News |  |
- || Preclinical, Review, Journal: Kallikrein inhibitors for angioedema: the progress of preclinical and early phase studies. (Pubmed Central) - Mar 11, 2024
The targeted treatment of the dysregulated kinin-kallikrein system with specific inhibitors is promising for the prevention of angioedema attacks. Ongoing phase III studies will provide further insight into the efficacy and long-term safety of these novel therapies, potentially expanding treatment options for HAE treatment.
- ||| IONIS-PKKRx / Ionis
Enrollment change: Efficacy and Safety of IONIS-PKKRx for Preventive Treatment of Chronic Migraine (clinicaltrials.gov) - Feb 5, 2020
P2, N=30, Completed, Sponsor: Smith, Timothy R., M.D.
Ongoing phase III studies will provide further insight into the efficacy and long-term safety of these novel therapies, potentially expanding treatment options for HAE treatment. N=43 --> 30
- || IONIS-PKKRx / Ionis
Trial completion: Efficacy and Safety of IONIS-PKKRx for Preventive Treatment of Chronic Migraine (clinicaltrials.gov) - May 1, 2019
P2, N=43, Completed, Sponsor: Smith, Timothy R., M.D.
N=43 --> 30 Active, not recruiting --> Completed
- | IONIS-PKKRx / Ionis
Trial completion date, Trial primary completion date: Efficacy and Safety of IONIS-PKKRx for Preventive Treatment of Chronic Migraine (clinicaltrials.gov) - Apr 4, 2019
P2, N=43, Active, not recruiting, Sponsor: Smith, Timothy R., M.D.
Active, not recruiting --> Completed Trial completion date: Dec 2018 --> Jun 2019 | Trial primary completion date: Dec 2018 --> Jun 2019
- | IONIS-PKKRx / Ionis
Enrollment closed, Enrollment change: Efficacy and Safety of IONIS-PKKRx for Preventive Treatment of Chronic Migraine (clinicaltrials.gov) - Sep 5, 2018
P2, N=43, Active, not recruiting, Sponsor: Smith, Timothy R., M.D.
Trial completion date: Dec 2018 --> Jun 2019 | Trial primary completion date: Dec 2018 --> Jun 2019 Recruiting --> Active, not recruiting | N=30 --> 43
- IONIS-PKKRx / Ionis
Trial completion date, Trial primary completion date: Efficacy and Safety of IONIS-PKKRx for Preventive Treatment of Chronic Migraine (clinicaltrials.gov) - Apr 18, 2018
P2, N=30, Recruiting, Sponsor: Smith, Timothy R., M.D.
Recruiting --> Active, not recruiting | N=30 --> 43 Trial completion date: Dec 2017 --> Dec 2018 | Trial primary completion date: Dec 2017 --> Dec 2018
- | IONIS-PKKRx / Ionis
Enrollment open: Efficacy and Safety of IONIS-PKKRx for Preventive Treatment of Chronic Migraine (clinicaltrials.gov) - Oct 5, 2017
P2, N=30, Recruiting, Sponsor: Smith, Timothy R., M.D.
Trial completion date: Dec 2017 --> Dec 2018 | Trial primary completion date: Dec 2017 --> Dec 2018 Not yet recruiting --> Recruiting
- | IONIS-PKKRx / Ionis
Trial initiation date: Efficacy and Safety of IONIS-PKKRx for Preventive Treatment of Chronic Migraine (clinicaltrials.gov) - Jun 16, 2017
P2, N=30, Not yet recruiting, Sponsor: Smith, Timothy R., M.D.
Not yet recruiting --> Recruiting Initiation date: May 2017 --> Jul 2017
- | IONIS-PKKRx / Ionis
New P2 trial: Efficacy and Safety of IONIS-PKKRx for Preventive Treatment of Chronic Migraine (clinicaltrials.gov) - Apr 10, 2017
P2, N=30, Not yet recruiting, Sponsor: Smith, Timothy R., M.D.