samuraciclib (CT7001) / Carrick Therap 
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 0 Diseases   1 Trial   1 Trial   3 News 
9 Trials

   

 
Trial + Data / EventsStatusPhNRegionInterventionsSponsorConditionsPrimary complStudy compl
samuraciclib (CT7001) / Carrick Therap
SUMIT-BC, NCT05963984 / 2023-503903-27-00: A Study of Samuraciclib in Combination With Fulvestrant in Metastatic or Locally Advanced Breast Cancer in Adult Participants

Completed
2
60
Europe, US, RoW
Samuraciclib, Fulvestrant, Faslodex
Carrick Therapeutics Limited, Pfizer
metastatic or locally advanced Hormone Receptor positive and Human Epidermal Growth Factor Receptor 2 negative breast cancer
03/25
08/25
SUMIT-ELA, NCT05963997 / 2023-503846-30-00: A Study of Samuraciclib and Elacestrant in Participants With Metastatic or Locally Advanced HR+/HER2-negative Breast Cancer

Completed
1/2
49
Europe, US
Samuraciclib, Elacestrant Dihydrochloride, ORSERDU
Carrick Therapeutics Limited, Berlin-Chemie AG Menarini Group
Metastatic Breast Cancer, Locally Advanced Breast Cancer, Breast Cancer
03/26
03/26
CT7001_003, 2023-503846-30-00: A study to test the effect of Samuraciclib in Combination with Elacestrant in Participants with Hormone Receptor-positive (HR+) and Human Epidermal Growth Factor Receptor 2-negative (HER2-) breast cancer

Active, not recruiting
1/2
48
Europe
CT7001, ORSERDU 345 mg film-coated tablets, ORSERDU 86 mg film-coated tablets
Carrick Therapeutics Limited
Breast Cancer
 
 
2023-503903-27-00: A Study of Samuraciclib in Combination With Fulvestrant in Metastatic or Locally Advanced HR Positive and HER2-Negative BC

Completed
1/2
24
Europe
Faslodex 250 mg solution for injection., CT7001 Tablet
Carrick Therapeutics Limited, Carrick Therapeutics Limited
metastatic or locally advanced Hormone Receptor positive and Human Epidermal Growth Factor Receptor 2 negative breast cancer
 
 
MORPHEUS BC, NCT04802759: A Study Evaluating the Efficacy and Safety of Multiple Treatment Combinations in Participants With Breast Cancer

Recruiting
1/2
316
Europe, US, RoW
Giredestrant, GDC-9545, RO7197597, RG6171, Abemaciclib, Verzenio?, Ipatasertib, GDC-0068, RO5532961, RG7440, Inavolisib, ITOVEBI?, GDC-0077, RO7113755, RG6114, Ribociclib, Kisqali?, Everolimus, Afinitor?, Samuraciclib, ICEC0942, CT7001, PH FDC SC, Pertuzumab, Trastuzumab, and Hyaluronidase-zzxf, PHESGO?, RO7198574, RG6264, Palbociclib, Ibrance?, Atezolizumab, Tecentriq?, RO5541267, RG7446
Hoffmann-La Roche
Inoperable, Locally Advanced or Metastatic, ER-positive Breast Cancer
05/29
05/29
SONIC, NCT07665684: Samuraciclib in Combination With Gemcitabine/Nab-Paclitaxel in Patients With Metastatic Basal-Like Pancreatic Cancer

Not yet recruiting
1/2
67
Canada
Samuraciclib + Gemcitabine & Nab-Paclitaxel
University Health Network, Toronto
Pancreas Ductal Adenocarcinoma, Pancreas Cancer, Metastatic, Pancreatic Adenocarcinoma Metastatic, Adenosquamous Carcinoma of the Pancreas, Mucinous Adenocarcinoma
05/29
05/30
C4891024, NCT06125522 / 2023-507125-41-00: TACTIVE-U: A Study to Learn About the Study Medicine (Vepdegestrant) When Given With Other Medicines in People With Advanced or Metastatic Breast Cancer. (Sub-Study C)

Terminated
1/2
11
Europe, US
vepdegestrant, ARV-471 / PF-07850327, Samuraciclib
Pfizer, Arvinas Estrogen Receptor, Inc., Carrick Therapeutics Limited, Rigel Pharmaceuticals,Inc.
Breast Cancer
09/26
09/26
C4891024, 2023-507125-41-00: TACTIVE-U: An Umbrella Study to Investigate the Safety and Antitumor Activity of vepdegestrant (ARV-471) in Combination With Other Medicines in Adults With ER+ Advanced or Metastatic Breast Cancer, Sub-study C (ARV-471 and Samuraciclib)

Completed
1/2
48
Europe
CT7001, PF-07850327 round
Pfizer Inc., Pfizer Inc
Advanced or Metastatic Breast Cancer
 
 
NCT07645651: Samuraciclib for the Treatment of Patients With Resectable, Borderline Resectable, or Locally Advanced Basal Pancreatic Cancer

Recruiting
1
15
US
Samuraciclib, CDK7 Inhibitor CT7001, CT 7001, CT-7001, CT7001, Computed Tomography, CAT, CAT Scan, Computed Axial Tomography, Computerized Axial Tomography, Computerized axial tomography (procedure), Computerized Tomography, Computerized Tomography (CT) scan, CT, CT Scan, Diagnostic CAT Scan, Diagnostic CAT Scan Service Type, tomography, Endoscopic Ultrasound Biopsy, Biospecimen Collection, Biological Sample Collection, Biospecimen Collected, Specimen Collection
University of Washington, Lopker Family Foundation, Carrick Therapeutics Limited, The V Foundation for Cancer Research
Resectable Pancreatic Ductal Adenocarcinoma, Borderline Resectable Pancreatic Ductal Adenocarcinoma, Locally Advanced Pancreatic Ductal Adenocarcinoma
07/27
11/27

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