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linrodostat
(BMS-986205) /
BMS, Ono Pharma
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0 Diseases
12 Trials
12 Trials
153 News
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linrodostat
(BMS-986205) /
BMS, Ono Pharma
New P1 trial:
A Study to Evaluate the Bioavailability of BMS-986205
(clinicaltrials.gov) - Dec 14, 2017
P1
, N=8, Not yet recruiting,
Sponsor: Bristol-Myers Squibb
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linrodostat
(BMS-986205) /
BMS, Ono Pharma
New P1 trial:
A Study to Assess the Absorption of a Single Dose of BMS-986205 in Healthy Volunteers When Administered as a Crushed Tablet Orally or Crushed Tablet Suspension Via Nasogastric Tube, as Compared to a Tablet
(clinicaltrials.gov) - Dec 5, 2017
P1
, N=40, Recruiting,
Sponsor: Bristol-Myers Squibb
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linrodostat
(BMS-986205) /
BMS, Ono Pharma
New P1 trial:
A Study to Evaluate the Effect of 2 Drugs on the Pharmacokinetics of BMS-986205 in Healthy Subjects
(clinicaltrials.gov) - Nov 17, 2017
P1
, N=56, Not yet recruiting,
Sponsor: Bristol-Myers Squibb
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Biomarker, New P1 trial, PD(L)-1 Biomarker, IO biomarker:
ADVISE: An Adaptive Study to Match Patients With Solid Tumors to Various Immunotherapy Combinations Based Upon a Broad Biomarker Assessment
(clinicaltrials.gov) - Nov 7, 2017
P1
, N=50, Not yet recruiting,
Sponsor: Bristol-Myers Squibb
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linrodostat
(BMS-986205) /
BMS, Ono Pharma
,
Opdivo
(nivolumab) /
BMS
New P3 trial, PD(L)-1 Biomarker:
An Investigational Immuno-therapy Study of BMS-986205 Combined With Nivolumab, Compared to Nivolumab by Itself, in Patients With Advanced Melanoma
(clinicaltrials.gov) - Nov 6, 2017
P3
, N=700, Not yet recruiting,
Sponsor: Bristol-Myers Squibb
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linrodostat
(BMS-986205) /
BMS, Ono Pharma
Trial completion:
Pharmacokinetics and Metabolism Study in Healthy Male Participants
(clinicaltrials.gov) - Nov 6, 2017
P1
, N=9, Completed,
Sponsor: Bristol-Myers Squibb
Recruiting --> Completed
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linrodostat
(BMS-986205) /
BMS, Ono Pharma
New P1 trial:
An Investigational Study to Assess the Effect of a Light Meal and a High-Fat Meal on the Absorption of BMS-986205 in Healthy Participants
(clinicaltrials.gov) - Oct 17, 2017
P1
, N=32, Recruiting,
Sponsor: Bristol-Myers Squibb
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linrodostat
(BMS-986205) /
BMS, Ono Pharma
New P1 trial:
Pharmacokinetics and Metabolism Study in Healthy Male Participants
(clinicaltrials.gov) - Aug 11, 2017
P1
, N=9, Recruiting,
Sponsor: Bristol-Myers Squibb
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linrodostat
(BMS-986205) /
BMS, Ono Pharma
,
Opdivo
(nivolumab) /
BMS
Enrollment open, PD(L)-1 Biomarker:
A Study of BMS-986205 Given in Combination With Nivolumab in Patients With Advanced Tumors
(clinicaltrials.gov) - Aug 1, 2017
P1
, N=18, Recruiting,
Sponsor: Bristol-Myers Squibb
Recruiting --> Completed Not yet recruiting --> Recruiting
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Enrollment change:
FRACTION-RCC: A Study to Test Combination Treatments in People With Advanced Renal Cell Carcinoma
(clinicaltrials.gov) - Jul 2, 2017
P2
, N=200, Recruiting,
Sponsor: Bristol-Myers Squibb
Not yet recruiting --> Recruiting N=650 --> 200
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linrodostat
(BMS-986205) /
BMS, Ono Pharma
,
Opdivo
(nivolumab) /
BMS
New P1 trial, PD(L)-1 Biomarker:
A Study of BMS-986205 Given in Combination With Nivolumab in Patients With Advanced Tumors
(clinicaltrials.gov) - Jun 20, 2017
P1
, N=18, Not yet recruiting,
Sponsor: Bristol-Myers Squibb
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Enrollment change:
FRACTION-GC: A Study to Test Combination Treatments in Participants With Advanced Gastric Cancer
(clinicaltrials.gov) - Jun 1, 2017
P2
, N=300, Recruiting,
Sponsor: Bristol-Myers Squibb
N=650 --> 200 N=910 --> 300
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linrodostat
(BMS-986205) /
BMS, Ono Pharma
,
Opdivo
(nivolumab) /
BMS
,
Yervoy
(ipilimumab) /
BMS
Enrollment change, Trial primary completion date:
An Investigational Immuno-therapy Study of BMS-986205 Given in Combination With Nivolumab and in Combination With Both Nivolumab and Ipilimumab in Cancers That Are Advanced or Have Spread
(clinicaltrials.gov) - May 30, 2017
P1/2
, N=907, Recruiting,
Sponsor: Bristol-Myers Squibb
N=910 --> 300 N=252 --> 907 | Trial primary completion date: Dec 2018 --> Apr 2019 | N=252 --> 907 | Trial primary completion date: Dec 2018 --> Apr 2019
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Enrollment open:
FRACTION-RCC: A Study to Test Combination Treatments in People With Advanced Renal Cell Carcinoma
(clinicaltrials.gov) - Feb 8, 2017
P2
, N=650, Recruiting,
Sponsor: Bristol-Myers Squibb
N=252 --> 907 | Trial primary completion date: Dec 2018 --> Apr 2019 | N=252 --> 907 | Trial primary completion date: Dec 2018 --> Apr 2019 Not yet recruiting --> Recruiting
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New P2 trial:
FRACTION-RCC: A Study to Test Combination Treatments in People With Advanced Renal Cell Carcinoma
(clinicaltrials.gov) - Dec 19, 2016
P2
, N=650, Not yet recruiting,
Sponsor: Bristol-Myers Squibb
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Enrollment open:
FRACTION-GC: A Study to Test Combination Treatments in Participants With Advanced Gastric Cancer
(clinicaltrials.gov) - Dec 1, 2016
P2
, N=910, Recruiting,
Sponsor: Bristol-Myers Squibb
Not yet recruiting --> Recruiting Not yet recruiting --> Recruiting
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New P2 trial:
FRACTION-GC: A Study to Test Combination Treatments in Participants With Advanced Gastric Cancer
(clinicaltrials.gov) - Oct 16, 2016
P2
, N=910, Not yet recruiting,
Sponsor: Bristol-Myers Squibb
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Trial primary completion date:
FRACTION-Lung: An Investigational Immuno-therapy Study to Test Combination Treatments in Patients With Advanced Non-Small Cell Lung Cancer
(clinicaltrials.gov) - Aug 9, 2016
P2
, N=504, Recruiting,
Sponsor: Bristol-Myers Squibb
Not yet recruiting --> Recruiting Trial primary completion date: Apr 2020 --> Apr 2021
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Enrollment change:
FRACTION-Lung: An Investigational Immuno-therapy Study to Test Combination Treatments in Patients With Advanced Non-Small Cell Lung Cancer
(clinicaltrials.gov) - Jun 13, 2016
P2
, N=504, Recruiting,
Sponsor: Bristol-Myers Squibb
Trial primary completion date: Apr 2020 --> Apr 2021 N=685 --> 504
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Enrollment open:
FRACTION-Lung: An Investigational Immuno-therapy Study to Test Combination Treatments in Patients With Advanced Non-Small Cell Lung Cancer
(clinicaltrials.gov) - May 22, 2016
P2
, N=685, Recruiting,
Sponsor: Bristol-Myers Squibb
N=685 --> 504 Not yet recruiting --> Recruiting
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New P2 trial:
FRACTION-Lung: An Investigational Immuno-therapy Study to Test Combination Treatments in Patients With Advanced Non-Small Cell Lung Cancer
(clinicaltrials.gov) - Apr 25, 2016
P2
, N=685, Not yet recruiting,
Sponsor: Bristol-Myers Squibb
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linrodostat
(BMS-986205) /
BMS, Ono Pharma
,
Opdivo
(nivolumab) /
BMS
,
Yervoy
(ipilimumab) /
BMS
Enrollment open:
An Investigational Immuno-therapy Study of BMS-986205 Given in Combination With Nivolumab and in Combination With Both Nivolumab and Ipilimumab in Cancers That Are Advanced or Have Spread
(clinicaltrials.gov) - Feb 26, 2016
P1/2
, N=252, Recruiting,
Sponsor: Bristol-Myers Squibb
Not yet recruiting --> Recruiting Not yet recruiting --> Recruiting
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linrodostat
(BMS-986205) /
BMS, Ono Pharma
,
Opdivo
(nivolumab) /
BMS
,
Yervoy
(ipilimumab) /
BMS
New P1/2 trial:
An Investigational Immuno-therapy Study of BMS-986205 Given in Combination With Nivolumab and in Combination With Both Nivolumab and Ipilimumab in Cancers That Are Advanced or Have Spread
(clinicaltrials.gov) - Jan 20, 2016
P1/2
, N=252, Not yet recruiting,
Sponsor: Bristol-Myers Squibb