- |||||||||| Neupogen (filgrastim) / Kyowa Kirin, Amgen, peripheral blood stem cell transplantation / National Cancer Institute
Trial completion date, Trial primary completion date: Chemotherapy and Stem Cell Transplantation in Treating Patients With Stage IIIB Breast Cancer (clinicaltrials.gov) - Oct 10, 2018 P2, N=60, Active, not recruiting, Active, not recruiting --> Recruiting Trial completion date: Sep 2018 --> Mar 2019 | Trial primary completion date: Sep 2018 --> Mar 2019
- |||||||||| Lartruvo (olaratumab) / Eli Lilly
Enrollment closed, Enrollment change, Trial completion date, Combination therapy, Monotherapy: A Study of Olaratumab (LY3012207) in Participants With Soft Tissue Sarcoma (clinicaltrials.gov) - Oct 5, 2018 P1b, N=61, Active, not recruiting, Recruiting --> Active, not recruiting Completed --> Active, not recruiting | N=40 --> 61 | Trial completion date: Jul 2018 --> Jun 2019
- |||||||||| Trial completion date: TAC Versus TC for Adjuvant Breast Cancer (clinicaltrials.gov) - Oct 1, 2018
P3, N=1296, Active, not recruiting, Recruiting --> Active, not recruiting Trial completion date: May 2017 --> May 2019
- |||||||||| Rituxan (rituximab) / Roche
Enrollment change, Trial completion date, Trial termination, Trial primary completion date, Metastases: Combination Chemotherapy With or Without Rituximab in Treating Participants With Stage III-IV Classic Hodgkin Lymphoma (clinicaltrials.gov) - Sep 28, 2018 P2, N=58, Terminated, N=50 --> 11 | Trial completion date: Apr 2020 --> Sep 2018 | Recruiting --> Terminated | Trial primary completion date: Jun 2019 --> Sep 2018; Sponsor withdrew funding N=120 --> 58 | Trial completion date: Mar 2020 --> Sep 2018 | Active, not recruiting --> Terminated | Trial primary completion date: Mar 2019 --> Sep 2018
- |||||||||| tamoxifen / Generic mfg.
Clinical, Journal: Rare case of metaplastic breast cancer in a man. (Pubmed Central) - Sep 28, 2018 Two years after treatment, he is currently living with no signs of recurrence. This case will serve as a useful addition to the current literature discussing successful diagnosis, treatment and prognosis of a man with MBC.
- |||||||||| doxorubicin hydrochloride / Generic mfg.
Journal: Tumor-targeting and pH-responsive nanoparticles from hyaluronic acid for the enhanced delivery of doxorubicin. (Pubmed Central) - Sep 27, 2018 Furthermore, confocal laser scanning microscopy (CLSM) images and flow cytometric profiles of HeLa cells showed an efficiently cellular uptake due to the receptor-mediated affinity of CD44 for HA with high specificity. These results suggest that this pH dependent drug delivery system based on HA will provide insights into the design of potential prodrugs for the cancer therapy.
- |||||||||| Rituxan (rituximab) / Biogen, Zenyaku Kogyo, Roche
Journal: Computerized Approach to Creating a Systematic Ontology of Hematology/Oncology Regimens. (Pubmed Central) - Sep 23, 2018 These capabilities may be particularly valuable in the implementation of rapid-learning health systems on the basis of real-world evidence. The derived Web Ontology Language ontology is freely available for noncommercial use through the Creative Commons 4.0 Attribution-NonCommercial-ShareAlike license.
- |||||||||| bortezomib / Generic mfg., melphalan / Generic mfg., thalidomide / Generic mfg.
Trial completion date, Trial primary completion date: UARK 2006-66, Total Therapy 3B: An Extension of UARK 2003-33 Total Therapy (clinicaltrials.gov) - Sep 19, 2018 P3, N=177, Active, not recruiting, N=18 --> 25 Trial completion date: Aug 2018 --> Aug 2019 | Trial primary completion date: Aug 2018 --> Aug 2019
- |||||||||| Polivy (polatuzumab vedotin-piiq) / Roche, Lunsumio (mosunetuzumab-axgb) / Roche, Biogen
New P1/2 trial, Combination therapy: GO40515: A Phase Ib/II Study Investigating the Safety, Tolerability, Pharmacokinetics, and Efficacy of Mosunetuzumab (BTCT4465A) in Combination With CHOP or CHP-Polatuzumab Vedotin in Participants With B-Cell Non-Hodgkin Lymphoma (clinicaltrials.gov) - Sep 19, 2018 P1/2, N=160, Not yet recruiting,
- |||||||||| doxorubicin hydrochloride / Generic mfg.
Enrollment change, Trial completion date, Trial withdrawal, Trial primary completion date: Cardiac Fibrosis by CMR in Patients With Cancer (clinicaltrials.gov) - Sep 14, 2018 P=N/A, N=0, Withdrawn, Trial completion date: Dec 2020 --> Jul 2020 | Trial primary completion date: Dec 2018 --> Jul 2019 N=12 --> 0 | Trial completion date: Feb 2019 --> Aug 2018 | Recruiting --> Withdrawn | Trial primary completion date: Jan 2019 --> Aug 2018
- |||||||||| plinabulin (BPI 2358) / BeyondSpring
Enrollment closed, Enrollment change, Trial completion date, Trial primary completion date: PROTECTIVE-2: Plinabulin vs. Pegfilgrastim in Prevention of TAC Induced Neutropenia (clinicaltrials.gov) - Sep 12, 2018 P2/3, N=237, Active, not recruiting, Trial primary completion date: Jun 2019 --> Feb 2020 Recruiting --> Active, not recruiting | N=180 --> 237 | Trial completion date: Dec 2018 --> Apr 2019 | Trial primary completion date: Jul 2018 --> Oct 2018
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