- |||||||||| Chantix (varenicline) / Pfizer
Biomarker, Trial completion, Trial completion date, Trial primary completion date: Pharmacogenetics, Emotional Reactivity and Smoking (clinicaltrials.gov) - Dec 23, 2019 P2/3, N=646, Completed, Phase classification: P=N/A --> P4 Active, not recruiting --> Completed | Trial completion date: Dec 2020 --> Dec 2019 | Trial primary completion date: Dec 2020 --> Dec 2019
- |||||||||| Chantix (varenicline) / Pfizer
Biomarker, Trial primary completion date: Pharmacogenetics, Emotional Reactivity and Smoking (clinicaltrials.gov) - Dec 20, 2019 P2/3, N=646, Active, not recruiting, Active, not recruiting --> Completed | Trial completion date: Dec 2020 --> Dec 2019 | Trial primary completion date: Dec 2020 --> Dec 2019 Trial primary completion date: Dec 2019 --> Dec 2020
- |||||||||| bupropion sustained-release / generics
Journal: Drugs for smoking cessation. (Pubmed Central) - Nov 18, 2019 The proportion of smokers who use smoking cessation medications who benefit from doing so decreases during the course of the first year, but a net benefit still remains at 12 months. No abstract available
- |||||||||| Chantix (varenicline) / Pfizer
Trial completion date, Trial primary completion date: Combining Varenicline and Bupropion for Smoking Cessation (clinicaltrials.gov) - Sep 3, 2019 P3, N=385, Active, not recruiting, It allows for the monitoring of thoughts and feelings associated with increased suicidal risk as well as levels of thoughts about suicide. Trial completion date: May 2020 --> May 2021 | Trial primary completion date: May 2019 --> May 2020
- |||||||||| bupropion sustained-release / Generic mfg.
Enrollment closed, Enrollment change, Trial completion date, Trial primary completion date: Mobile Contingency Management for Concurrent Abstinence From Alcohol and Smoking (clinicaltrials.gov) - Aug 19, 2019 P=N/A, N=45, Active, not recruiting, Its curative effect is close to that of bupropion hydrochloride sustained-release tablets, and it has good clinical compliance and less adverse reactions. Recruiting --> Active, not recruiting | N=10 --> 45 | Trial completion date: Feb 2021 --> Feb 2020 | Trial primary completion date: Nov 2020 --> Feb 2020
- |||||||||| Chantix (varenicline) / Pfizer
Enrollment closed, Enrollment change: Treating Smokeless Tobacco Use in Rural Veterans (clinicaltrials.gov) - Jul 24, 2019 P=N/A, N=123, Active, not recruiting, Recruiting --> Completed | N=60 --> 40 Enrolling by invitation --> Active, not recruiting | N=50 --> 123
- |||||||||| NN1213 / Novo Nordisk
Trial completion, Enrollment change, Trial completion date, Trial primary completion date: Evaluation of CYP450 Activities in Diabetic Patients vs. Non-diabetic Subjects (clinicaltrials.gov) - Jul 23, 2019 P4, N=73, Completed, Enrolling by invitation --> Active, not recruiting | N=50 --> 123 Recruiting --> Completed | N=126 --> 73 | Trial completion date: Oct 2019 --> Jul 2019 | Trial primary completion date: Jan 2019 --> Jul 2019
- |||||||||| NN1213 / Novo Nordisk
Enrollment closed, Enrollment change: Smoking Cessation for People Living With HIV/AIDS (clinicaltrials.gov) - Jul 22, 2019 P=N/A, N=165, Active, not recruiting, Recruiting --> Completed | N=126 --> 73 | Trial completion date: Oct 2019 --> Jul 2019 | Trial primary completion date: Jan 2019 --> Jul 2019 Recruiting --> Active, not recruiting | N=400 --> 165
- |||||||||| NN1213 / Novo Nordisk
Trial completion date, Trial primary completion date: Smoking Cessation for People Living With HIV/AIDS (clinicaltrials.gov) - Jul 11, 2019 P=N/A, N=400, Recruiting, Recruiting --> Active, not recruiting | N=400 --> 165 Trial completion date: Dec 2019 --> Jul 2020 | Trial primary completion date: Dec 2019 --> Jul 2020
- |||||||||| Auvelity (bupropion/dextromethorphan) / Axsome Therap
Trial completion: AXS-05 Phase II Trial on Smoking Behavior (clinicaltrials.gov) - Jun 12, 2019 P2, N=58, Completed, Trial completion date: Dec 2019 --> Jul 2020 | Trial primary completion date: Dec 2019 --> Jul 2020 Active, not recruiting --> Completed
- |||||||||| Auvelity (bupropion/dextromethorphan) / Axsome Therap
Enrollment closed: AXS-05 Phase II Trial on Smoking Behavior (clinicaltrials.gov) - May 13, 2019 P2, N=60, Active, not recruiting, Trial completion date: May 2019 --> May 2020 Recruiting --> Active, not recruiting
- |||||||||| Auvelity (bupropion/dextromethorphan) / Axsome Therap
Trial completion date, Trial primary completion date: AXS-05 Phase II Trial on Smoking Behavior (clinicaltrials.gov) - Jan 14, 2019 P2, N=60, Recruiting, Initiation date: Jan 2019 --> Aug 2019 Trial completion date: Jan 2019 --> May 2019 | Trial primary completion date: Dec 2018 --> Mar 2019
- |||||||||| Chantix (varenicline) / Pfizer, NN1213 / Novo Nordisk
Enrollment closed, Trial primary completion date: Web-based Smoking Cessation Program for Tribal College Students (clinicaltrials.gov) - Oct 12, 2018 P3, N=300, Active, not recruiting, These findings indicate the important roles of varenicline in negative affect processing and negative emotional reactivity in the course of smoking cessation. Recruiting --> Active, not recruiting | Trial primary completion date: Jun 2018 --> Mar 2019
- |||||||||| NN1213 / Novo Nordisk
Trial completion date, Trial primary completion date: Smoking Cessation for People Living With HIV/AIDS (clinicaltrials.gov) - Oct 4, 2018 P=N/A, N=400, Recruiting, Recruiting --> Active, not recruiting Trial completion date: Jun 2019 --> Dec 2019 | Trial primary completion date: Jun 2019 --> Dec 2019
- |||||||||| bupropion sustained-release / Generic mfg.
Trial completion, Phase classification, Enrollment change: Combined Pharmaco/Behavior Therapy in Adolescent Smokers (clinicaltrials.gov) - Oct 2, 2018 P2, N=134, Completed, Trial completion date: Jun 2019 --> Dec 2019 | Trial primary completion date: Jun 2019 --> Dec 2019 Recruiting --> Completed | Phase classification: PN/A --> P2 | N=216 --> 134
- |||||||||| bupropion sustained-release / Generic mfg.
Journal: Step Care treatment for smoking cessation. (Pubmed Central) - Jul 18, 2018 Recruiting --> Completed | Phase classification: PN/A --> P2 | N=216 --> 134 For smokers not achieving tobacco abstinence 6 months after randomization with Step 1, the intensity of the intervention increased to four counseling sessions, bupropion sustained-release, nine telephone calls and three mailings (Step 2)...No abstract available
- |||||||||| NN1213 / Novo Nordisk
Enrollment change, Trial completion date, Trial termination, Trial primary completion date: Bupropion for Depression in ESRD Patients on Hemodialysis (clinicaltrials.gov) - Jul 17, 2018 P4, N=1, Terminated, For smokers not achieving tobacco abstinence 6 months after randomization with Step 1, the intensity of the intervention increased to four counseling sessions, bupropion sustained-release, nine telephone calls and three mailings (Step 2)...No abstract available N=40 --> 1 | Trial completion date: Dec 2018 --> Mar 2018 | Recruiting --> Terminated | Trial primary completion date: Sep 2018 --> Mar 2018; Study stopped due to difficulty recruiting
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