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Trial + Data / Events	Status	Ph	N	Region	Interventions	Sponsor	Conditions	Primary compl	Study compl
Orladeyo (berotralstat) / BioCryst
APeX-P, NCT05453968 / 2021-005932-50: Berotralstat Treatment in Children With Hereditary Angioedema	Active, not recruiting	3	29	Europe, Canada, RoW	Berotralstat, BCX7353, Orladeyo®	BioCryst Pharmaceuticals	Hereditary Angioedema, Pediatric	07/25	07/27
APeX-A, NCT04933721 / 2020-004230-37: Open-label Berotralstat Access to HAE Patients Previously Enrolled in Berotralstat Studies	Active, not recruiting	3	110	Europe, RoW	berotralstat, Orladeyo	BioCryst Pharmaceuticals	Hereditary Angioedema, HAE	08/26	08/26
2015-003923-74: A placebo controlled trial of of three doses of BCX7353 to evaluate the safety and efficacy in the prevention of attacks in patients with HAE	Ongoing	2	24	Europe	BC7353, BCX7353, Capsule, hard	BioCryst Pharmaceuticals Inc, BioCryst Pharmaceutical Inc	Hereditary Angioedema, Hereditary Angioedema, Diseases [C] - Blood and lymphatic diseases [C15]