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70 Diseases |  |
70 Trials |
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70 Trials |  |
2588 News |  |
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- || Activase (alteplase) / Roche, Boehringer Ingelheim, Kyowa Kirin, Mitsubishi Tanabe
Enrollment closed: ACCESS PTS: Treatment of Chronic Deep Vein Thrombosis (DVT) and Post-Thrombotic Syndrome (PTS) With the EkoSonic® Endovascular System (clinicaltrials.gov) - Jun 5, 2014
P=N/A, N=200, Active, not recruiting, Sponsor: EKOS Corporation
Not yet recruiting --> Active, not recruiting
- | Activase (alteplase) / Roche, Boehringer Ingelheim, Kyowa Kirin, Mitsubishi Tanabe
Enrollment change: Efficacy and Safety of Actilyse 2 mg/ 2 ml in Comparison to Saline Solution in Patients With Central Venous Access Device Occlusion (clinicaltrials.gov) - May 27, 2014
P3, N=16, Completed, Sponsor: Boehringer Ingelheim
Not yet recruiting --> Active, not recruiting N=88 --> 16
- || Activase (alteplase) / Roche, Boehringer Ingelheim, Kyowa Kirin, Mitsubishi Tanabe
Trial completion: Efficacy and Safety of Actilyse 2 mg/ 2 ml in Comparison to Saline Solution in Patients With Central Venous Access Device Occlusion (clinicaltrials.gov) - May 27, 2014
P3, N=16, Completed, Sponsor: Boehringer Ingelheim
N=88 --> 16 Active, not recruiting --> Completed
- |||| Activase (alteplase) / Roche, Boehringer Ingelheim, Kyowa Kirin, Mitsubishi Tanabe
Trial primary completion date: Efficacy and Safety of Actilyse 2 mg/ 2 ml in Comparison to Saline Solution in Patients With Central Venous Access Device Occlusion (clinicaltrials.gov) - May 11, 2014
P3, N=88, Recruiting, Sponsor: Boehringer Ingelheim
Active, not recruiting --> Completed Trial primary completion date: Apr 2014 --> Jun 2014
- ||| Activase (alteplase) / Roche, Boehringer Ingelheim, Kyowa Kirin, Mitsubishi Tanabe
Trial completion date: Efficacy and Safety of Actilyse 2 mg/ 2 ml in Comparison to Saline Solution in Patients With Central Venous Access Device Occlusion (clinicaltrials.gov) - May 11, 2014
P3, N=88, Recruiting, Sponsor: Boehringer Ingelheim
Trial primary completion date: Apr 2014 --> Jun 2014 Trial completion date: Apr 2014 --> Jun 2014
- |||||| Activase (alteplase) / Roche, Boehringer Ingelheim, Kyowa Kirin, Mitsubishi Tanabe
Enrollment open: Efficacy and Safety of Actilyse 2 mg/ 2 ml in Comparison to Saline Solution in Patients With Central Venous Access Device Occlusion (clinicaltrials.gov) - May 11, 2014
P3, N=88, Recruiting, Sponsor: Boehringer Ingelheim
Trial completion date: Apr 2014 --> Jun 2014 Completed --> Recruiting
- | Activase (alteplase) / Roche, Boehringer Ingelheim, Kyowa Kirin, Mitsubishi Tanabe
New P4 trial: CONTACT-SPE: Comparison of Thrombgolytic and Anticoagulation Therapy in Submassive Pulmonary Embolism (clinicaltrials.gov) - May 5, 2014
P4, N=100, Recruiting, Sponsor: University Hospital Ostrava
- ||||| Activase (alteplase) / Roche, Boehringer Ingelheim, Kyowa Kirin, Mitsubishi Tanabe
Trial initiation date: PRISMS: A Study of the Efficacy and Safety of Alteplase in Participants With Mild Stroke (clinicaltrials.gov) - May 4, 2014
P3, N=948, Recruiting, Sponsor: Genentech
Completed --> Recruiting Initiation date: Apr 2014 --> May 2014
- Activase (alteplase) / Roche, Boehringer Ingelheim, Kyowa Kirin, Mitsubishi Tanabe
Trial termination: TURANDOT: Thrombectomy Under Reopro Versus Alteplase to Treat Stoke (clinicaltrials.gov) - Apr 23, 2014
P4, N=40, Terminated, Sponsor: SOS Attaque Cérébrale
Initiation date: Apr 2014 --> May 2014 Recruiting --> Terminated
- |||||| Activase (alteplase) / Roche, Boehringer Ingelheim, Kyowa Kirin, Mitsubishi Tanabe
Enrollment open: PRISMS: A Study of the Efficacy and Safety of Alteplase in Participants With Mild Stroke (clinicaltrials.gov) - Apr 13, 2014
P3, N=948, Recruiting, Sponsor: Genentech
Recruiting --> Terminated Not yet recruiting --> Recruiting
- | Lucentis (ranibizumab) / Roche, Novartis, Activase (alteplase) / Roche, Boehringer Ingelheim, Kyowa Kirin, Mitsubishi Tanabe
Trial initiation date: TAPAS: Intravitreal tPA and C3F8 for the Treatment of Submacular Haemorrhage as a Complication of Neovascular AMD (clinicaltrials.gov) - Mar 19, 2014
P2/3, N=55, Recruiting, Sponsor: King's College Hospital NHS Trust
Not yet recruiting --> Recruiting Initiation date: May 2013 --> Sep 2013
- | Lucentis (ranibizumab) / Roche, Novartis, Activase (alteplase) / Roche, Boehringer Ingelheim, Kyowa Kirin, Mitsubishi Tanabe
Enrollment open: TAPAS: Intravitreal tPA and C3F8 for the Treatment of Submacular Haemorrhage as a Complication of Neovascular AMD (clinicaltrials.gov) - Mar 19, 2014
P2/3, N=55, Recruiting, Sponsor: King's College Hospital NHS Trust
Initiation date: May 2013 --> Sep 2013 Not yet recruiting --> Recruiting
- |||||||||| Activase (alteplase) / Roche, Boehringer Ingelheim, Kyowa Kirin, Mitsubishi Tanabe
New P3 trial: PRISMS: A Study of the Efficacy and Safety of Alteplase in Participants With Mild Stroke (clinicaltrials.gov) - Feb 24, 2014
P3, N=948, Recruiting, Sponsor: Genentech
- Activase (alteplase) / Roche, Boehringer Ingelheim, Kyowa Kirin, Mitsubishi Tanabe
Trial initiation date: Effect of Intraventricular tPA Following Aneurysmal Subarachnoid Hemorrhage (clinicaltrials.gov) - Jan 23, 2014
P1/2, N=50, Not yet recruiting, Sponsor: Rush University Medical Center
Not yet recruiting --> Recruiting Initiation date: Jul 2013 --> Jun 2014
- | Activase (alteplase) / Roche, Boehringer Ingelheim, Kyowa Kirin, Mitsubishi Tanabe
Enrollment open, Surgery: MISTIE III: Minimally Invasive Surgery Plus Rt-PA for ICH Evacuation Phase III (clinicaltrials.gov) - Jan 14, 2014
P3, N=500, Recruiting, Sponsor: Daniel Hanley
Initiation date: Jul 2013 --> Jun 2014 Not yet recruiting --> Recruiting
- Activase (alteplase) / Roche, Boehringer Ingelheim, Kyowa Kirin, Mitsubishi Tanabe
New P4 trial: Low Dose Prolonged Infusion of Tissue Type Plasminogen Activator Therapy in Massive Pulmonary Embolism (clinicaltrials.gov) - Jan 6, 2014
P4, N=30, Recruiting, Sponsor: Ahi Evren Chest and Cardiovascular Surgery Education and Research Hospital
- Activase (alteplase) / Roche, Boehringer Ingelheim, Kyowa Kirin, Mitsubishi Tanabe
New P4 trial: TURANDOT: Thrombectomy Under Reopro Versus Alteplase to Treat Stoke (clinicaltrials.gov) - Dec 18, 2013
P4, N=40, Terminated, Sponsor: SOS Attaque Cérébrale
- | Activase (alteplase) / Roche, Boehringer Ingelheim, Kyowa Kirin, Mitsubishi Tanabe
Trial initiation date, Surgery: MISTIE III: Minimally Invasive Surgery Plus Rt-PA for ICH Evacuation Phase III (clinicaltrials.gov) - Dec 11, 2013
P3, N=500, Recruiting, Sponsor: Daniel Hanley
Not yet recruiting --> Recruiting Initiation date: Sep 2013 --> Dec 2013
- || Activase (alteplase) / Roche, Boehringer Ingelheim, Kyowa Kirin, Mitsubishi Tanabe
New P3 trial: THrombolysis for Acute Wake-up and Unclear-onset Strokes With Alteplase at 0.6 mg/kg Trial (THAWS) (clinicaltrials.gov) - Dec 3, 2013
P3, N=300, Not yet recruiting, Sponsor: National Cerebral and Cardiovascular Center
- Activase (alteplase) / Roche, Boehringer Ingelheim, Kyowa Kirin, Mitsubishi Tanabe
Trial termination: IMSIII: Interventional Management of Stroke (IMS) III Trial (clinicaltrials.gov) - Nov 18, 2013
P3, N=656, Terminated, Sponsor: Joseph Broderick
Initiation date: Sep 2013 --> Dec 2013 Active, not recruiting --> Terminated; NINDS/NIH-DSMB recommended halting trial due to futility, no safety concerns.
- Activase (alteplase) / Roche, Boehringer Ingelheim, Kyowa Kirin, Mitsubishi Tanabe
Enrollment change: IMSIII: Interventional Management of Stroke (IMS) III Trial (clinicaltrials.gov) - Nov 18, 2013
P3, N=656, Terminated, Sponsor: Joseph Broderick
Active, not recruiting --> Terminated; NINDS/NIH-DSMB recommended halting trial due to futility, no safety concerns. N=900 --> 656
- ||| Activase (alteplase) / Roche, Boehringer Ingelheim, Kyowa Kirin, Mitsubishi Tanabe
New P3 trial: Efficacy and Safety of Actilyse 2 mg/ 2 ml in Comparison to Saline Solution in Patients With Central Venous Access Device Occlusion (clinicaltrials.gov) - Oct 7, 2013
P3, N=16, Completed, Sponsor: Boehringer Ingelheim
- | Activase (alteplase) / Roche, Boehringer Ingelheim, Kyowa Kirin, Mitsubishi Tanabe
New P4 trial, Combination therapy: Comparison of Low-Molecular-Weight Heparin (LMWH) and Unfractionated Heparin (UFH) in Combination With Thrombolytic Treatment of Acute Massive Pulmonary Thromboembolism (clinicaltrials.gov) - Oct 6, 2013
P4, N=150, Recruiting, Sponsor: Ataturk University
- || TNKASE (tenecteplase) / Roche, Boehringer Ingelheim, Activase (alteplase) / Roche, Boehringer Ingelheim, Kyowa Kirin, Mitsubishi Tanabe
New P3 trial: THE NOR-TEST STUDY: Study of Tenecteplase Versus Alteplase for Thrombolysis (Clot Dissolving) in Acute Ischemic Stroke (clinicaltrials.gov) - Sep 23, 2013
P3, N=954, Recruiting, Sponsor: Lars Thomassen
- Activase (alteplase) / Roche, Boehringer Ingelheim, Kyowa Kirin, Mitsubishi Tanabe
Trial withdrawal: AWOKE: Study for the Use of Alteplase in Patients Who Awaken With Stroke (clinicaltrials.gov) - Sep 10, 2013
P1, N=0, Withdrawn, Sponsor: University of California, San Diego
N=900 --> 656 Recruiting --> Withdrawn
- Activase (alteplase) / Roche, Boehringer Ingelheim, Kyowa Kirin, Mitsubishi Tanabe
Enrollment change: AWOKE: Study for the Use of Alteplase in Patients Who Awaken With Stroke (clinicaltrials.gov) - Sep 10, 2013
P1, N=0, Withdrawn, Sponsor: University of California, San Diego
Recruiting --> Withdrawn N=20 --> 0
- | Activase (alteplase) / Roche, Boehringer Ingelheim, Kyowa Kirin, Mitsubishi Tanabe
New P4 trial: EARLY-MYO: EARLY Routine Catheterization After Alteplase Fibrinolysis vs. PPCI in ST-Segment-Elevation MYOcardial Infarction (clinicaltrials.gov) - Aug 18, 2013
P4, N=350, Not yet recruiting, Sponsor: RenJi Hospital
- ||| Activase (alteplase) / Roche, Boehringer Ingelheim, Kyowa Kirin, Mitsubishi Tanabe
Trial initiation date: Assess the Penumbra System in the Treatment of Acute Stroke (clinicaltrials.gov) - Aug 18, 2013
P4, N=692, Recruiting, Sponsor: Penumbra Inc.
N=20 --> 0 Initiation date: Jan 2012 --> May 2012
- || Activase (alteplase) / Roche, Boehringer Ingelheim, Kyowa Kirin, Mitsubishi Tanabe
New P3 trial: Extending the time for thrombolytic treatment after stroke. (EUDRACT) - Jun 17, 2013
P3, N=264, Ongoing, Sponsor: Ruprecht-Karls-University Heidelberg, Medical Faculty
- Activase (alteplase) / Roche, Boehringer Ingelheim, Kyowa Kirin, Mitsubishi Tanabe
New P1/2 trial: Effect of Intraventricular tPA Following Aneurysmal Subarachnoid Hemorrhage (clinicaltrials.gov) - Jun 12, 2013
P1/2, N=50, Not yet recruiting, Sponsor: Rush University Medical Center
- ||||| Activase (alteplase) / Roche, Boehringer Ingelheim, Kyowa Kirin, Mitsubishi Tanabe
Enrollment change: SEATTLE II: Submassive and Massive Pulmonary Embolism Treatment With Ultrasound Accelerated Thrombolysis Therapy (clinicaltrials.gov) - Jun 10, 2013
P3, N=150, Completed, Sponsor: EKOS Corporation
Initiation date: Jan 2012 --> May 2012 N=120 --> 150
- ||||||| Activase (alteplase) / Roche, Boehringer Ingelheim, Kyowa Kirin, Mitsubishi Tanabe
Trial completion: SEATTLE II: Submassive and Massive Pulmonary Embolism Treatment With Ultrasound Accelerated Thrombolysis Therapy (clinicaltrials.gov) - Jun 10, 2013
P3, N=150, Completed, Sponsor: EKOS Corporation
N=120 --> 150 Recruiting --> Completed
- Activase (alteplase) / Roche, Boehringer Ingelheim, Kyowa Kirin, Mitsubishi Tanabe
Trial completion, Surgery: MISTIE: Minimally Invasive Surgery and rtPA for Intracerebral Hemorrhage Evacuation (clinicaltrials.gov) - Jun 4, 2013
P2, N=143, Completed, Sponsor: Daniel Hanley
Recruiting --> Completed Active, not recruiting --> Completed
- || Activase (alteplase) / Roche, Boehringer Ingelheim, Kyowa Kirin, Mitsubishi Tanabe
New P3 trial: Prevention of narrowing of the biliary tree tract after liver transplantation by flushing the donor liver with a clot-dissolving agent Het voorkomen van vernauwingen van de galwegen na levertransplantatie door de donorlever te spoelen met een stolseloplossend medicijn (EUDRACT) - Jun 3, 2013
P3, N=194, Ongoing, Sponsor: Leiden University Medical Center
- |||| Activase (alteplase) / Roche, Boehringer Ingelheim, Kyowa Kirin, Mitsubishi Tanabe
Trial completion: Echoplanar Imaging Thrombolysis Evaluation Trial (EPITHET) (clinicaltrials.gov) - May 27, 2013
P2, N=100, Completed, Sponsor: Melbourne Health
Active, not recruiting --> Completed Active, not recruiting --> Completed
- | Activase (alteplase) / Roche, Boehringer Ingelheim, Kyowa Kirin, Mitsubishi Tanabe
Enrollment open: EXTEND (International): Extending the Time for Thrombolysis in Emergency Neurological Deficits (International) (clinicaltrials.gov) - Apr 29, 2013
P3, N=200, Recruiting, Sponsor: National Stroke Research Institute, Australia
Active, not recruiting --> Completed Not yet recruiting --> Recruiting
- || Lucentis (ranibizumab) / Roche, Novartis, Activase (alteplase) / Roche, Boehringer Ingelheim, Kyowa Kirin, Mitsubishi Tanabe
New P2/3 trial: TAPAS: Intravitreal tPA and C3F8 for the Treatment of Submacular Haemorrhage as a Complication of Neovascular AMD (clinicaltrials.gov) - Apr 16, 2013
P2/3, N=55, Recruiting, Sponsor: King's College Hospital NHS Trust
- || Activase (alteplase) / Roche, Boehringer Ingelheim, Kyowa Kirin, Mitsubishi Tanabe
New P3 trial, Surgery: MISTIE III: Minimally Invasive Surgery Plus Rt-PA for ICH Evacuation Phase III (clinicaltrials.gov) - Apr 7, 2013
P3, N=500, Recruiting, Sponsor: Daniel Hanley
- | Activase (alteplase) / Roche, Boehringer Ingelheim, Kyowa Kirin, Mitsubishi Tanabe
Trial initiation date: SAIL-ON: Safety of Intravenous Thrombolytics in Stroke on Awakening (clinicaltrials.gov) - Jan 27, 2013
P2, N=20, Recruiting, Sponsor: Johns Hopkins University
Not yet recruiting --> Recruiting Initiation date: Sep 2012 --> Jan 2013
- | Activase (alteplase) / Roche, Boehringer Ingelheim, Kyowa Kirin, Mitsubishi Tanabe
Enrollment open: SAIL-ON: Safety of Intravenous Thrombolytics in Stroke on Awakening (clinicaltrials.gov) - Jan 27, 2013
P2, N=20, Recruiting, Sponsor: Johns Hopkins University
Initiation date: Sep 2012 --> Jan 2013 Not yet recruiting --> Recruiting
- | Pulmozyme (dornase alfa) / Roche, Activase (alteplase) / Roche, Boehringer Ingelheim, Kyowa Kirin, Mitsubishi Tanabe
Enrollment open: Intrapleural DNase and Tissue Plasminogen Activator in Pediatric Empyema (DTPA Trial) (clinicaltrials.gov) - Jan 6, 2013
P3, N=98, Recruiting, Sponsor: The Hospital for Sick Children
Not yet recruiting --> Recruiting Not yet recruiting --> Recruiting
- Activase (alteplase) / Roche, Boehringer Ingelheim, Kyowa Kirin, Mitsubishi Tanabe
Enrollment change, Combination therapy: A pilot study of Argatroban combined with TPA (alteplase) for the treatment of acute stroke. (EUDRACT) - Dec 4, 2012
P2, N=105, Ongoing, Sponsor: University of Texas Health Science Center
Not yet recruiting --> Recruiting N=50 --> 105
- | Activase (alteplase) / Roche, Boehringer Ingelheim, Kyowa Kirin, Mitsubishi Tanabe
New P4 trial: Vienna Interventional Management of Stroke Study (EUDRACT) - Nov 21, 2012
P4, N=120, Ongoing, Sponsor: Med. Uni. Wien, UK für Neurologie
- | Activase (alteplase) / Roche, Boehringer Ingelheim, Kyowa Kirin, Mitsubishi Tanabe
Trial initiation date: Efficacy and Safety of MRI-based Thrombolysis in Wake-up Stroke (clinicaltrials.gov) - Nov 1, 2012
P3, N=800, Recruiting, Sponsor: Universitätsklinikum Hamburg-Eppendorf
N=50 --> 105 Initiation date: Jun 2012 --> Sep 2012
- | Activase (alteplase) / Roche, Boehringer Ingelheim, Kyowa Kirin, Mitsubishi Tanabe
Enrollment open: Efficacy and Safety of MRI-based Thrombolysis in Wake-up Stroke (clinicaltrials.gov) - Nov 1, 2012
P3, N=800, Recruiting, Sponsor: Universitätsklinikum Hamburg-Eppendorf
Initiation date: Jun 2012 --> Sep 2012 Not yet recruiting --> Recruiting
- || Pulmozyme (dornase alfa) / Roche, Activase (alteplase) / Roche, Boehringer Ingelheim, Kyowa Kirin, Mitsubishi Tanabe
New P3 trial: Intrapleural DNase and Tissue Plasminogen Activator in Pediatric Empyema (DTPA Trial) (clinicaltrials.gov) - Oct 28, 2012
P3, N=98, Recruiting, Sponsor: The Hospital for Sick Children
- | Activase (alteplase) / Roche, Boehringer Ingelheim, Kyowa Kirin, Mitsubishi Tanabe
New P2 trial, Combination therapy: A pilot study of Argatroban combined with TPA (alteplase) for the treatment of acute stroke. (EUDRACT) - Oct 15, 2012
P2, N=105, Ongoing, Sponsor: University of Texas Health Science Center
- Activase (alteplase) / Roche, Boehringer Ingelheim, Kyowa Kirin, Mitsubishi Tanabe
Enrollment change, Surgery: MISTIE: Minimally Invasive Surgery and rtPA for Intracerebral Hemorrhage Evacuation (clinicaltrials.gov) - Sep 18, 2012
P2, N=143, Completed, Sponsor: Daniel Hanley
Not yet recruiting --> Recruiting N=110 --> 143
- | Activase (alteplase) / Roche, Boehringer Ingelheim, Kyowa Kirin, Mitsubishi Tanabe
Trial completion: SYNTHESIS EXP: Intra-arterial Versus Systemic Thrombolysis for Acute Ischemic Stroke (clinicaltrials.gov) - Sep 10, 2012
P3, N=350, Completed, Sponsor: Niguarda Hospital
N=110 --> 143 Recruiting --> Completed
- TNKASE (tenecteplase) / Roche, Boehringer Ingelheim, Activase (alteplase) / Roche, Boehringer Ingelheim, Kyowa Kirin, Mitsubishi Tanabe
Enrollment open: Alteplase-Tenecteplase Trial Evaluation for Stroke Thrombolysis- (ATTEST) (clinicaltrials.gov) - Aug 8, 2012
P2, N=104, Recruiting, Sponsor: NHS Greater Glasgow and Clyde
Recruiting --> Completed Not yet recruiting --> Recruiting