Libtayo (cemiplimab-rwlc) / Regeneron 
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 1 Disease   67 Trials   67 Trials   1555 News 


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  • ||||||||||  Libtayo (cemiplimab-rwlc) / Regeneron
    Trial primary completion date:  EMPOWER-Cervical 1: Study of Cemiplimab in Adults With Cervical Cancer (clinicaltrials.gov) -  Jun 21, 2019   
    P3,  N=436, Recruiting, 
    Not yet recruiting --> Recruiting Trial primary completion date: Jan 2022 --> Apr 2023
  • ||||||||||  Biomarker, Journal, PD(L)-1 Biomarker, IO Biomarker:  What's new in oncodermatology? (Pubmed Central) -  Jun 15, 2019   
    We also have a new anti-BRAF + anti-MEK combination: encorafenib + binimetinib with a good benefit/risk ratio and a particularly favorable safety profile as compared with existing similar combinations. Major steps forward were obtained for locally advanced Merkel cell carcinoma and squamous cell carcinoma with anti-PDL-1 avelumab and anti-PD1 cemiplimab respectively.
  • ||||||||||  Libtayo (cemiplimab) / Sanofi, Regeneron
    Journal:  Cemiplimab effective in cutaneous SCC. (Pubmed Central) -  May 17, 2019   
    Trial primary completion date: Apr 2019 --> Dec 2019 No abstract available
  • ||||||||||  Libtayo (cemiplimab-rwlc) / Regeneron
    Enrollment open:  CASE: CemiplimAb Survivorship Epidemiology (clinicaltrials.gov) -  Apr 16, 2019   
    P=N/A,  N=350, Recruiting, 
    Not yet recruiting --> Recruiting Not yet recruiting --> Recruiting
  • ||||||||||  Libtayo (cemiplimab-rwlc) / Regeneron
    Enrollment closed, Enrollment change, Trial completion date, Trial primary completion date, IO biomarker:  EMPOWER-lung 4: A Study of REGN2810 and Ipilimumab in Patients With Lung Cancer (clinicaltrials.gov) -  Apr 8, 2019   
    P2,  N=28, Active, not recruiting, 
    Trial completion date: Jul 2022 --> Feb 2023 | Trial primary completion date: Jul 2022 --> Feb 2023 Recruiting --> Active, not recruiting | N=252 --> 28 | Trial completion date: Jan 2022 --> Apr 2020 | Trial primary completion date: Jan 2022 --> Apr 2020
  • ||||||||||  Opdivo (nivolumab) / Ono Pharma, BMS, Yervoy (ipilimumab) / Ono Pharma, BMS
    Clinical, Clinical guideline, Review, Journal, Adverse events, Checkpoint inhibition:  Management of Immune-Related Adverse Events Associated with Immune Checkpoint Inhibitor Therapy: a Minireview of Current Clinical Guidelines. (Pubmed Central) -  Apr 2, 2019   
    Herein, we review the mechanisms of irAEs and strategies for management of irAEs and highlight similarities as well as differences among clinical guidelines from the National Comprehensive Cancer Network, American Society of Clinical Oncology, Society for Immunotherapy of Cancer, and European Society for Medical Oncology. Understanding these similarities and key differences will facilitate the development and implementation of a practice site-specific plan for the management of irAEs.
  • ||||||||||  Sarclisa (isatuximab-irfc) / Sanofi
    Trial completion date, Trial primary completion date:  Isatuximab in Combination With REGN2810 (Cemiplimab) in Patients With Advanced Malignancies (clinicaltrials.gov) -  Mar 26, 2019   
    P1/2,  N=134, Recruiting, 
    Trial completion date: Jul 2023 --> Mar 2021 | Trial primary completion date: Jul 2023 --> Mar 2021 Trial completion date: Aug 2022 --> Jul 2021 | Trial primary completion date: Aug 2022 --> Jul 2021
  • ||||||||||  Hiltonol (poly-ICLC) / Oncovir
    Trial completion date, Trial primary completion date:  In Situ, Autologous Therapeutic Vaccination Against Solid Cancers With Intratumoral Hiltonol (clinicaltrials.gov) -  Mar 13, 2019   
    P2,  N=100, Recruiting, 
    Trial completion date: Aug 2022 --> Jul 2021 | Trial primary completion date: Aug 2022 --> Jul 2021 Trial completion date: Dec 2020 --> Dec 2021 | Trial primary completion date: Dec 2018 --> Jun 2021
  • ||||||||||  Sarclisa (isatuximab-irfc) / Sanofi
    Trial completion date, Trial primary completion date:  A Study of Isatuximab-based Therapy in Participants With Lymphoma (clinicaltrials.gov) -  Mar 12, 2019   
    P1/2,  N=130, Recruiting, 
    Trial completion date: Dec 2020 --> Dec 2021 | Trial primary completion date: Dec 2018 --> Jun 2021 Trial completion date: Jun 2022 --> Jan 2023 | Trial primary completion date: Jun 2022 --> Jan 2023
  • ||||||||||  Libtayo (cemiplimab-rwlc) / Regeneron
    New trial:  CASE: CemiplimAb Survivorship Epidemiology (clinicaltrials.gov) -  Feb 10, 2019   
    P,  N=350, Not yet recruiting, 
  • ||||||||||  ISA101 / ISA Pharma
    Enrollment open:  OpcemISA: A Randomized Phase 2 Study of Cemiplimab  (clinicaltrials.gov) -  Dec 17, 2018   
    P2,  N=164, Recruiting, 
    Not yet recruiting --> Recruiting Not yet recruiting --> Recruiting
  • ||||||||||  Sarclisa (isatuximab-irfc) / Sanofi
    Trial completion date, Trial primary completion date:  Isatuximab in Combination With Cemiplimab in Relapsed/Refractory Multiple Myeloma (RRMM) Patients (clinicaltrials.gov) -  Oct 25, 2018   
    P1/2,  N=105, Recruiting, 
    N=300 --> 700 | Trial completion date: Sep 2021 --> Sep 2022 | Trial primary completion date: Sep 2021 --> Sep 2022 Trial completion date: Jan 2021 --> Aug 2022 | Trial primary completion date: Jan 2021 --> Aug 2022