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8 Diseases |  |
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0 Trials |  |
7 News |  |
- | GSK2981710 / GSK
Clinical, Journal: The effects of GSK2981710, a medium-chain triglyceride, on cognitive function in healthy older participants: A randomised, placebo-controlled study. (Pubmed Central) - Apr 1, 2020
Over a duration of 14 days, increasing plasma BHB levels with daily administration of GSK2981710 had no effects on neuronal activity or cognitive function. This result indicates that modulating plasma ketone levels with GSK2981710 may be ineffective in improving cognitive function in healthy older adults, or the lack of observed effect could be related to several factors including study population, plasma BHB concentrations, MCT composition, or treatment duration.
- || GSK2981710 / GSK
Enrollment change: Effects of Triglycerides on Age-Related Cognitive Function Decline in Older Subjects (clinicaltrials.gov) - May 9, 2017
P1, N=116, Completed, Sponsor: GlaxoSmithKline
This result indicates that modulating plasma ketone levels with GSK2981710 may be ineffective in improving cognitive function in healthy older adults, or the lack of observed effect could be related to several factors including study population, plasma BHB concentrations, MCT composition, or treatment duration. N=96 --> 116
- || GSK2981710 / GSK
Enrollment change: Effects of Triglycerides on Age-Related Cognitive Function Decline in Older Subjects (clinicaltrials.gov) - Dec 14, 2015
P1, N=107, Completed, Sponsor: GlaxoSmithKline
N=96 --> 116 N=33 --> 107
- GSK2981710 / GSK
Trial completion, Enrollment change, Trial primary completion date: Effects of Triglycerides on Age-Related Cognitive Function Decline in Older Subjects (clinicaltrials.gov) - Jul 13, 2015
P1, N=33, Completed, Sponsor: GlaxoSmithKline
N=33 --> 107 Recruiting --> Completed | N=88 --> 33 | Trial primary completion date: Oct 2015 --> Jul 2015
- || GSK2981710 / GSK
Trial primary completion date: Effects of Triglycerides on Age-Related Cognitive Function Decline in Older Subjects (clinicaltrials.gov) - Jul 30, 2014
P1, N=88, Recruiting, Sponsor: GlaxoSmithKline
Recruiting --> Completed | N=88 --> 33 | Trial primary completion date: Oct 2015 --> Jul 2015 Trial primary completion date: Apr 2014 --> Oct 2015
- ||| GSK2981710 / GSK
Enrollment open: Effects of Triglycerides on Age-Related Cognitive Function Decline in Older Subjects (clinicaltrials.gov) - Dec 5, 2012
P1, N=88, Recruiting, Sponsor: GlaxoSmithKline
Trial primary completion date: Apr 2014 --> Oct 2015 Not yet recruiting --> Recruiting
- ||| GSK2981710 / GSK
New P1 trial: Effects of Triglycerides on Age-Related Cognitive Function Decline in Older Subjects (clinicaltrials.gov) - Oct 4, 2012
P1, N=88, Recruiting, Sponsor: GlaxoSmithKline