leucovorin calcium / Generic mfg. 
Welcome,         Profile    Billing    Logout  
 424 Diseases   807 Trials   807 Trials   14372 News 


«12...188189190191192193194195196197198...235236»
  • ||||||||||  saridegib oral (IPI 926 oral) / Infinity Pharma
    Trial completion, Enrollment change, Trial initiation date, Trial primary completion date, Metastases:  FOLFIRINOX Plus IPI-926 for Advanced Pancreatic Adenocarcinoma (clinicaltrials.gov) -  Aug 8, 2017   
    P1,  N=15, Completed, 
    Trial primary completion date: Jul 2017 --> Jan 2021 Recruiting --> Completed | N=21 --> 15 | Initiation date: Nov 2014 --> Aug 2011 | Trial primary completion date: Nov 2017 --> Dec 2012
  • ||||||||||  Avastin (bevacizumab) / Roche
    Journal:  Phase II Study of Modified FOLFOX6 With Bevacizumab in Metastatic Gastroesophageal Adenocarcinoma. (Pubmed Central) -  Aug 3, 2017   
    First-line mFOLFOX6 with bevacizumab for metastatic gastroesophageal adenocarcinoma was well tolerated and associated with longer PFS and OS compared with historical data from similar populations treated without bevacizumab. Our results suggest that the addition of bevacizumab to mFOLFOX6 may provide clinical benefit in American patients with metastatic gastroesophageal adenocarcinoma, a finding consistent with previous studies of first-line bevacizumab in combination with chemotherapy for this disease.
  • ||||||||||  conatumumab (AMG 655) / Amgen
    Trial primary completion date:  Open Label Extension Study of Conatumumab and Ganitumab (AMG 479) (clinicaltrials.gov) -  Jul 31, 2017   
    P2,  N=12, Active, not recruiting, 
    Trial primary completion date: Jan 2018 --> Nov 2018 Trial primary completion date: Jul 2017 --> Jan 2018
  • ||||||||||  Stivarga (regorafenib) / Bayer
    Trial initiation date, Monotherapy, Metastases:  Regorafenib Plus 5-Fluorouracil/Leucovorin Beyond Progression in mCRC (clinicaltrials.gov) -  Jul 31, 2017   
    P2,  N=15, Not yet recruiting, 
    Trial primary completion date: Jul 2017 --> Jan 2018 Initiation date: Jun 2017 --> Oct 2017
  • ||||||||||  erlotinib / Generic mfg., Onivyde (nanoliposomal irinotecan) / Servier, Ipsen, Takeda, Abraxane (albumin-bound paclitaxel) / BMS, Otsuka
    Journal:  Metastatic Pancreatic Cancer: American Society of Clinical Oncology Clinical Practice Guideline. (Pubmed Central) -  Jul 29, 2017   
    For second-line therapy, gemcitabine plus NAB-paclitaxel should be offered to patients with first-line treatment with FOLFIRINOX, an ECOG PS 0 to 1, and a favorable comorbidity profile; fluorouracil plus oxaliplatin, irinotecan, or nanoliposomal irinotecan should be offered to patients with first-line treatment with gemcitabine plus NAB-paclitaxel, ECOG PS 0 to 1, and favorable comorbidity profile, and gemcitabine or fluorouracil should be offered to patients with either an ECOG PS 2 or a comorbidity profile that precludes other regimens. Additional information is available at www.asco.org/guidelines/MetPC and www.asco.org/guidelineswiki.
  • ||||||||||  Decadron (dexamethasone) / Merck (MSD), Oncaspar liquid (pegaspargase) / Servier
    Enrollment open, Trial primary completion date:  DFCI 16-001: Treatment of Newly Diagnosed Acute Lymphoblastic Leukemia in Children and Adolescents (clinicaltrials.gov) -  Jul 28, 2017   
    P3,  N=400, Recruiting, 
    Although differences were nonsignificant, IC plus cetuximab seemed to be the least effective and most toxic of the three regimens tested. Not yet recruiting --> Recruiting | Trial primary completion date: May 2021 --> Dec 2021
  • ||||||||||  Avastin (bevacizumab) / Roche
    Trial primary completion date, Metastases:  AXEPT: A Phase III Study of 2nd-line XELIRI  (clinicaltrials.gov) -  Jul 27, 2017   
    P3,  N=650, Active, not recruiting, 
    Not yet recruiting --> Recruiting | Trial primary completion date: May 2021 --> Dec 2021 Trial primary completion date: Jan 2017 --> Nov 2017
  • ||||||||||  Otrexup (methotrexate) / Halozyme, Rituxan (rituximab) / Roche
    Trial primary completion date:  Chemotherapy and HAART to Treat AIDS-related Primary Brain Lymphoma (clinicaltrials.gov) -  Jul 21, 2017   
    P2,  N=28, Recruiting, 
    Trial primary completion date: Jan 2017 --> Nov 2017 Trial primary completion date: Jul 2018 --> Jul 2019
  • ||||||||||  5-fluorouracil / Generic mfg., metformin / Generic mfg., leucovorin calcium / Generic mfg.
    Trial primary completion date, Metastases:  Metformin Plus Modified FOLFOX 6 in Metastatic Pancreatic Cancer (clinicaltrials.gov) -  Jul 19, 2017   
    P2,  N=43, Recruiting, 
    Trial primary completion date: Jul 2018 --> Jul 2019 Trial primary completion date: Apr 2017 --> Oct 2017
  • ||||||||||  locnartecan (PEN-866) - Tarveda Therap, National Cancer Institute / Bethesda
    New P1/2 trial, Metastases:  PEN-866 in Patients With Advanced Solid Malignancies (clinicaltrials.gov) -  Jul 18, 2017   
    P1/2,  N=150, Recruiting, 
  • ||||||||||  Arzerra (ofatumumab) / Novartis, Genmab, Rituxan (rituximab) / Roche
    Trial completion, Trial primary completion date:  Ofatumumab With IVAC Salvage Chemotherapy in Diffuse Large B Cell Lymphoma Patients (clinicaltrials.gov) -  Jul 17, 2017   
    P2,  N=77, Completed, 
    Not yet recruiting --> Enrolling by invitation Recruiting --> Completed | Trial primary completion date: Oct 2017 --> Jul 2017
  • ||||||||||  dilpacimab (ABT-165) / AbbVie
    Enrollment closed, Trial primary completion date, Metastases:  A Study of ABT-165 in Subjects With Solid Tumors (clinicaltrials.gov) -  Jul 13, 2017   
    P1,  N=90, Active, not recruiting, 
    N=204 --> 257 | Trial primary completion date: Jun 2017 --> Nov 2015 Recruiting --> Active, not recruiting | Trial primary completion date: Jun 2018 --> Feb 2018